amantadine and methylphenidate

amantadine has been researched along with methylphenidate in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19906 (17.14)18.7374
1990's1 (2.86)18.2507
2000's14 (40.00)29.6817
2010's12 (34.29)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jeste, DV; Wyatt, RJ1
Costall, B; Naylor, RJ3
Ananth, J; Ruskin, R1
Cashin, CH; Sutton, S1
Morris, K1
Rosati, DL1
Christodoulou, C; Krupp, LB1
Fleminger, S; Greenwood, RJ; Oliver, DL2
Collins, L; Silver, BV; Zidek, KA1
Blackman, JA; Buck, ML; Conaway, MR; Patrick, PD1
Elovic, EP; Napolitano, E; Qureshi, AI1
Pachler, M; Scahill, L1
Barrett, AM; Gonzalez Rothi, LJ; Levy, CE1
Lombardi, F1
Elsner, F; Krumm, N; Peuckmann, V; Radbruch, L; Trottenberg, P1
Meehan, WP1
Akhondzadeh, S; Kazemi, MR; Mohammadi, MR; Rezazadeh, SA; Tabrizi, M; Zia, E1
Li, R; Mao, S; Yang, R; Zhao, Z1
Callaway, CW; Reynolds, JC; Rittenberger, JC1
Cossu, G1
Cuhls, H; Minton, O; Mücke, M; Peuckmann-Post, V; Radbruch, L; Stone, P1
Canning, SD; Wang, XP; Zhang, LL1
Luauté, J; Plantier, D; Tell, L; Wiart, L1
Nourbakhsh, B; Revirajan, N; Waubant, E1
Aljarallah, S; Auvray, C; Cordano, C; Creasman, J; Jin, C; Krysko, K; Manguinao, M; McCulloch, C; Morris, B; Mowry, E; Nourbakhsh, B; Revirajan, N; Rutatangwa, A; Waubant, E1
Bourdette, D1

Reviews

13 review(s) available for amantadine and methylphenidate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
In search of treatment for tardive dyskinesia: review of the literature.
    Schizophrenia bulletin, 1979, Volume: 5, Issue:2

    Topics: Amantadine; Antipsychotic Agents; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Levodopa; Lithium; Methylphenidate; Parasympatholytics; Parasympathomimetics; Patient Dropouts; Research Design

1979
Fatigue in multiple sclerosis.
    Current neurology and neuroscience reports, 2001, Volume: 1, Issue:3

    Topics: Amantadine; Autoimmune Diseases; Benzhydryl Compounds; Brain; Case Management; Central Nervous System Stimulants; Combined Modality Therapy; Cross-Over Studies; Depression; Double-Blind Method; Fatigue; Hot Temperature; Humans; Hypothalamus; Methylphenidate; Modafinil; Multiple Sclerosis; Patient Care Team; Pemoline; Physical Therapy Modalities; Pilot Projects; Randomized Controlled Trials as Topic; Self-Assessment; Severity of Illness Index; Tomography, Emission-Computed

2001
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2003, Issue:1

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidate; Neuroprotective Agents; Pindolol; Propranolol; Randomized Controlled Trials as Topic

2003
Pharmacological stimulant treatment of neurocognitive and functional deficits after traumatic and non-traumatic brain injury.
    Medical science monitor : international medical journal of experimental and clinical research, 2005, Volume: 11, Issue:6

    Topics: Amantadine; Animals; Brain Injuries; Bromocriptine; Cognition Disorders; Dextroamphetamine; Humans; Levodopa; Methylphenidate

2005
Pharmacological management for agitation and aggression in people with acquired brain injury.
    The Cochrane database of systematic reviews, 2006, Oct-18, Issue:4

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anxiety; Brain Injuries; Humans; Methylphenidate; Neuroprotective Agents; Pindolol; Propranolol; Psychomotor Agitation; Randomized Controlled Trials as Topic

2006
Treatment of hyperactivity in children with pervasive developmental disorders.
    Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc, 2007, Volume: 20, Issue:1

    Topics: Adrenergic alpha-Agonists; Amantadine; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child Development Disorders, Pervasive; Child Psychiatry; Dopamine Agents; Guanfacine; Humans; Methylphenidate; Naltrexone; Narcotic Antagonists; Patient Selection; Treatment Outcome

2007
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2010, Nov-10, Issue:11

    Topics: Adult; Amantadine; Benzhydryl Compounds; Central Nervous System Stimulants; Fatigue; Humans; Kidney Failure, Chronic; Methylphenidate; Modafinil; Multiple Sclerosis; Neoplasms; Palliative Care; Pemoline; Randomized Controlled Trials as Topic

2010
Medical therapies for concussion.
    Clinics in sports medicine, 2011, Volume: 30, Issue:1

    Topics: Amantadine; Analgesics, Non-Narcotic; Antiparkinson Agents; Athletic Injuries; Brain Concussion; Brain Injuries; Central Nervous System Stimulants; Cognition; Cognition Disorders; Humans; Methylphenidate; Sleep Wake Disorders; Sports Medicine; Trauma Severity Indices

2011
Therapeutic options to enhance coma arousal after traumatic brain injury: state of the art of current treatments to improve coma recovery.
    British journal of neurosurgery, 2014, Volume: 28, Issue:2

    Topics: Amantadine; Arousal; Brain Injuries; Cell Transplantation; Central Nervous System Stimulants; Coma; Deep Brain Stimulation; Dopamine Agents; Drug Therapy; Electric Stimulation Therapy; Glasgow Coma Scale; Humans; Hyperbaric Oxygenation; Median Nerve; Methylphenidate; Recovery of Function; Spinal Cord; Transcranial Magnetic Stimulation; Treatment Outcome

2014
Pharmacological treatments for fatigue associated with palliative care.
    The Cochrane database of systematic reviews, 2015, May-30, Issue:5

    Topics: Adult; Amantadine; Benzhydryl Compounds; Carnitine; Central Nervous System Stimulants; Chronic Disease; Fatigue; Humans; Kidney Failure, Chronic; Methylphenidate; Modafinil; Multiple Sclerosis; Neoplasms; Palliative Care; Pemoline; Randomized Controlled Trials as Topic

2015
Freezing of Gait in Parkinsonism and its Potential Drug Treatment.
    Current neuropharmacology, 2016, Volume: 14, Issue:4

    Topics: Aged; Aged, 80 and over; Amantadine; Antiparkinson Agents; Botulinum Toxins; Droxidopa; Gait Disorders, Neurologic; Humans; Indans; Levodopa; Methylphenidate; Middle Aged; Monoamine Oxidase Inhibitors; Parkinsonian Disorders; Selegiline; Treatment Outcome

2016
Care management of the agitation or aggressiveness crisis in patients with TBI. Systematic review of the literature and practice recommendations.
    Annals of physical and rehabilitation medicine, 2016, Volume: 59, Issue:1

    Topics: Adrenergic beta-Antagonists; Aggression; Amantadine; Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Brain Injuries; Buspirone; Central Nervous System Stimulants; Dopamine Agents; Humans; Methylphenidate; Psychomotor Agitation; Restraint, Physical

2016

Trials

3 trial(s) available for amantadine and methylphenidate

ArticleYear
Amantadine versus methylphenidate in children and adolescents with attention deficit/hyperactivity disorder: a randomized, double-blind trial.
    Human psychopharmacology, 2010, Volume: 25, Issue:7-8

    Topics: Adolescent; Amantadine; Attention Deficit Disorder with Hyperactivity; Child; Dopamine Agents; Dopamine Uptake Inhibitors; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Methylphenidate; Psychiatric Status Rating Scales; Treatment Outcome

2010
Treatment of fatigue with methylphenidate, modafinil and amantadine in multiple sclerosis (TRIUMPHANT-MS): Study design for a pragmatic, randomized, double-blind, crossover clinical trial.
    Contemporary clinical trials, 2018, Volume: 64

    Topics: Amantadine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Fatigue; Humans; Methylphenidate; Modafinil; Multiple Sclerosis; Research Design

2018
Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial.
    The Lancet. Neurology, 2021, Volume: 20, Issue:1

    Topics: Adult; Amantadine; Central Nervous System Stimulants; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug-Related Side Effects and Adverse Reactions; Fatigue; Female; Humans; Male; Methylphenidate; Middle Aged; Modafinil; Multiple Sclerosis; Outcome Assessment, Health Care; Severity of Illness Index

2021

Other Studies

19 other study(ies) available for amantadine and methylphenidate

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A comparison of circling models for the detection of antiparkinson activity.
    Psychopharmacologia, 1975, Volume: 41, Issue:1

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Behavior; Brain; Dextroamphetamine; Dopamine; Haloperidol; Humans; Isoquinolines; Levodopa; Male; Methylphenidate; Methyltyrosines; Piperazines; Rats; Reserpine; Rotation; Stereotaxic Techniques; Stereotyped Behavior; Substantia Nigra; Thalamic Nuclei

1975
Actions of dopaminergic agonists on motor function.
    Advances in neurology, 1975, Volume: 9

    Topics: Amantadine; Animals; Apomorphine; Behavior; Dextroamphetamine; Disease Models, Animal; Dopamine Antagonists; Humans; Hyperkinesis; Levodopa; Methylphenidate; Motor Activity; Movement Disorders; Phenethylamines; Piribedil; Rats; Stereotyped Behavior; Tyrosine

1975
Dopamine agonist and antagonist activities of piribedil (ET495)and its metabolites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:1

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Caudate Nucleus; Dextroamphetamine; Dioxoles; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Humans; Injections; Male; Methylphenidate; Motor Activity; Nialamide; Piperazines; Pyrimidines; Rats; Stereotyped Behavior; Sulfites

1974
Treatment of intractable depression.
    International pharmacopsychiatry, 1974, Volume: 9, Issue:4

    Topics: Amantadine; Antidepressive Agents; Depression; Dextroamphetamine; Drug Therapy, Combination; Hormones; Humans; Lithium; Methylphenidate; Monoamine Oxidase Inhibitors; Reserpine; Sleep Deprivation; Tryptophan; Vitamins

1974
The effect of anti-Parkinson drugs on catalepsy induced by -methyl-p-tyrosine in rats pretreated with intraventricular 6-hydroxydopamine.
    British journal of pharmacology, 1973, Volume: 47, Issue:3

    Topics: Amantadine; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Benztropine; Brain Chemistry; Catalepsy; Dextroamphetamine; Dihydroxyphenylalanine; Humans; Hydroxydopamines; Methylphenidate; Methyltyrosines; Rats; Reserpine; Scopolamine

1973
Seeking ways to crack cocaine addiction.
    Lancet (London, England), 1998, Oct-17, Volume: 352, Issue:9136

    Topics: Amantadine; Clinical Trials as Topic; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Humans; Ibogaine; Methylphenidate; Selegiline

1998
Early polyneuropharmacologic intervention in brain injury agitation.
    American journal of physical medicine & rehabilitation, 2002, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Amantadine; Antipsychotic Agents; Brain Injuries; Dextroamphetamine; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypnotics and Sedatives; Injury Severity Score; Longitudinal Studies; Male; Methylphenidate; Middle Aged; Neuropharmacology; Psychomotor Agitation; Trauma Centers; Trazodone; Treatment Outcome

2002
Risperidone treatment of motor restlessness following anoxic brain injury.
    Brain injury, 2003, Volume: 17, Issue:3

    Topics: Adolescent; Amantadine; Brain Injuries; Dopamine Agents; Drug Therapy, Combination; Humans; Hypoxia, Brain; Male; Methylphenidate; Psychomotor Agitation; Risperidone; Serotonin Antagonists; Treatment Outcome

2003
The use of dopamine enhancing medications with children in low response states following brain injury.
    Brain injury, 2003, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Amantadine; Arousal; Awareness; Benzothiazoles; Brain Injuries; Bromocriptine; Child; Dopamine Agents; Dopamine Agonists; Female; Humans; Levodopa; Male; Methylphenidate; Neuropsychological Tests; Pramipexole; Retrospective Studies; Thiazoles; Treatment Outcome; Unconsciousness

2003
Pharmaceuticals for poststroke and brain injury rehabilitation.
    American journal of physical medicine & rehabilitation, 2007, Volume: 86, Issue:8

    Topics: Amantadine; Aphasia, Broca; Brain Injuries; Dopamine Agents; Humans; Methylphenidate; Persistent Vegetative State; Stroke; Stroke Rehabilitation

2007
Pharmacological treatment of neurobehavioural sequelae of traumatic brain injury.
    European journal of anaesthesiology. Supplement, 2008, Volume: 42

    Topics: Amantadine; Animals; Antidepressive Agents; Antipsychotic Agents; Brain Injuries; Cognition; Cognition Disorders; Guidelines as Topic; Humans; Methylphenidate; Nervous System Diseases; Neurology; Psychomotor Agitation; Selective Serotonin Reuptake Inhibitors

2008
Several concerns arise when the results are interpreted.
    Human psychopharmacology, 2011, Volume: 26, Issue:1

    Topics: Amantadine; Attention Deficit Disorder with Hyperactivity; Dopamine Agents; Dopamine Uptake Inhibitors; Female; Humans; Male; Methylphenidate

2011
Methylphenidate and amantadine to stimulate reawakening in comatose patients resuscitated from cardiac arrest.
    Resuscitation, 2013, Volume: 84, Issue:6

    Topics: Adult; Aged; Amantadine; Cardiopulmonary Resuscitation; Central Nervous System Stimulants; Cohort Studies; Coma; Female; Heart Arrest; Humans; Male; Methylphenidate; Middle Aged; Patient Discharge; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult

2013
Are drugs for multiple sclerosis fatigue just placebos?
    The Lancet. Neurology, 2021, Volume: 20, Issue:1

    Topics: Amantadine; Double-Blind Method; Fatigue; Humans; Methylphenidate; Modafinil; Multiple Sclerosis; Pharmaceutical Preparations

2021