amantadine and methadone

amantadine has been researched along with methadone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's5 (27.78)18.2507
2000's6 (33.33)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brown, BS; Haertzen, CC; Jaffe, JH; Kolar, AF; Michaelson, BS; Weddington, WW1
Falcione, J; Kosten, TR; Morgan, CM; Schottenfeld, RS1
Kosten, TR; Morgan, CH; Schottenfeld, RS1
Chordia, PL; Escovar, IL; Handelsman, L; Lowinson, JH; Marion, IJ1
Ahtee, L; Kääriäinen, I; Paasonen, MK1
Kosten, T; Leal, J; Ziedonis, D1
Handelsman, L; Limpitlaw, L; Paris, P; Schmeidler, J; Stimmel, B; Williams, D1
Batlle, F; Casas, M; Duro, P; Pérez de los Cobos, J; Ribalta, E; Tejero, A; Trujols, J1
Anderson, CA; Arciniegas, DB; Brousseau, KM; Frey, KL; Harris, SN1
Amato, L; Amin-Esmaeili, M; Gholami, J; Hoseinie, L; Rahimi-Movaghar, A; Yousefi-Nooraie, R1

Reviews

2 review(s) available for amantadine and methadone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacological therapies for management of opium withdrawal.
    The Cochrane database of systematic reviews, 2018, 06-21, Volume: 6

    Topics: Amantadine; Amines; Baclofen; Buprenorphine; Clonidine; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Humans; Methadone; Opioid-Related Disorders; Opium; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome; Tramadol

2018

Trials

6 trial(s) available for amantadine and methadone

ArticleYear
Treatment of cocaine dependence in methadone maintenance clients: a pilot study comparing the efficacy of desipramine and amantadine.
    The International journal of the addictions, 1992, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Amantadine; Baltimore; Cocaine; Desipramine; Female; Follow-Up Studies; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Pilot Projects; Placebos; Research Design; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders; United States

1992
Pharmacotherapy for cocaine-abusing methadone-maintained patients using amantadine or desipramine.
    Archives of general psychiatry, 1992, Volume: 49, Issue:11

    Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioid-Related Disorders; Placebos; Substance Abuse Detection; Substance-Related Disorders; Treatment Outcome

1992
Amantadine and desipramine in the treatment of cocaine abusing methadone maintained patients.
    NIDA research monograph, 1990, Volume: 105

    Topics: Adult; Amantadine; Cocaine; Desipramine; Double-Blind Method; Female; Humans; Male; Methadone; Opioid-Related Disorders; Substance-Related Disorders

1990
Antisocial personality disorder as a prognostic factor for pharmacotherapy of cocaine dependence.
    Drug and alcohol dependence, 1994, Volume: 35, Issue:1

    Topics: Adult; Amantadine; Antisocial Personality Disorder; Cocaine; Combined Modality Therapy; Comorbidity; Depressive Disorder; Desipramine; Double-Blind Method; Female; Follow-Up Studies; Heroin Dependence; Humans; Male; Methadone; Patient Dropouts; Substance Abuse Detection; Substance-Related Disorders

1994
Amantadine does not reduce cocaine use or craving in cocaine-dependent methadone maintenance patients.
    Drug and alcohol dependence, 1995, Volume: 39, Issue:3

    Topics: Adult; Amantadine; Cocaine; Dopamine Agonists; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders

1995
Methadone tapering plus amantadine to detoxify heroin-dependent inpatients with or without an active cocaine use disorder: two randomised controlled trials.
    Drug and alcohol dependence, 2001, Jul-01, Volume: 63, Issue:2

    Topics: Adolescent; Adult; Amantadine; Cocaine-Related Disorders; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Neurologic Examination; Patient Admission; Substance Withdrawal Syndrome; Treatment Outcome

2001

Other Studies

10 other study(ies) available for amantadine and methadone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Amantadine for treatment of cocaine dependence in methadone-maintained patients.
    The American journal of psychiatry, 1988, Volume: 145, Issue:4

    Topics: Adult; Amantadine; Cocaine; Female; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Substance-Related Disorders

1988
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
    Annales medicinae experimentalis et biologiae Fenniae, 1972, Volume: 50, Issue:4

    Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methadone; Muscle Rigidity; Muscle Tonus; Nalorphine; Parasympatholytics; Phenylacetates; Rats; Serotonin; Spectrometry, Fluorescence; Trihexyphenidyl

1972
Amantadine for neurobehavioural deficits following delayed post-hypoxic encephalopathy.
    Brain injury, 2004, Volume: 18, Issue:12

    Topics: Adult; Amantadine; Brain; Brain Injuries; Cognition Disorders; Demyelinating Diseases; Diazepam; Dopamine Agents; Humans; Hypnotics and Sedatives; Hypoxia-Ischemia, Brain; Magnetic Resonance Imaging; Male; Mental Disorders; Methadone; Narcotics

2004