amantadine and ketamine

amantadine has been researched along with ketamine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's4 (15.38)18.2507
2000's13 (50.00)29.6817
2010's4 (15.38)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Topliss, JG; Yoshida, F1
Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA1
Almonte, A; Balster, R; Barber, J; Dravid, SM; Erreger, K; French, A; Le, P; Lyuboslavsky, P; Mosely, C; Murray, E; Murray, TF; Nicholson, K; Traynelis, SF; Yuan, H1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brea, JM; Companys-Alemany, J; Griñán-Ferré, C; Johnson, JW; Kurnikova, MG; Loza, MI; Pallàs, M; Patel, DS; Pérez, B; Phillips, MB; Soto, D; Sureda, FX; Turcu, AL; Vázquez, S1
Bonezzi, C; Mapelli, A; Pagani, I1
DeDonato, A; Lucca, GP; Montanari, C1
Carbonera, D; Domenichini, E; Pagnin, A; Scherini, A1
Feuerstein, TJ1
Krishtal, OA; Panchenko, VA; Parsons, CG; Pinchenko, VO; Tsyndrenko, AY1
Karge, E; Kerst, S; Klinger, W; Lupp, A; Quack, G1
Krisztin-Péva, B; Mihály, A; Szakács, R; Weiczner, R; Zádor, E; Zádor, Z1
Block, F; Habermeyer, B1
Amlie-Lefond, CM; Chusid, MJ; Ghanayem, NS; Hoffman, GM; Rupprecht, CE; Schwabe, MJ; Tieves, KS; Willoughby, RE1
Jackson, AC2
Inomata, S; Kakiuchi, Y; Kohda, Y; Miyabe, M; Ohara, Y; Osaka, Y; Sukegawa, I; Toyooka, H1
Howland, RH1
Maeng, S; Zarate, CA1
David, D; Garcia, C; Guarda, DC; Rubin, J; Rupprecht, CE; Stamler, A; Willoughby, RE; Zohar, Z1
Mamie, C1
Fouilhé Sam-Laï, N; Jouanjus, E; Lapeyre-Mestre, M; Revol, B1

Reviews

5 review(s) available for amantadine and ketamine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Glutamate antagonists for treatment of neuropathic pain].
    Schmerz (Berlin, Germany), 2003, Volume: 17, Issue:4

    Topics: Amantadine; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Humans; Ketamine; Memantine; Neuralgia

2003
Glutamate-modulating drugs & the treatment of mental disorders.
    Journal of psychosocial nursing and mental health services, 2007, Volume: 45, Issue:1

    Topics: Acamprosate; Amantadine; Cycloserine; Glutamic Acid; Humans; Ketamine; Lamotrigine; Memantine; Mental Disorders; Psychotropic Drugs; Riluzole; Taurine; Triazines

2007
The role of glutamate in mood disorders: results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects.
    Current psychiatry reports, 2007, Volume: 9, Issue:6

    Topics: Amantadine; Depressive Disorder, Major; Dopamine Agents; Excitatory Amino Acid Antagonists; Humans; Ketamine; Memantine; Mood Disorders; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate

2007
[Prevention of postoperative hyperalgesia].
    Annales francaises d'anesthesie et de reanimation, 2012, Volume: 31, Issue:1

    Topics: Amantadine; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Ketamine; Magnesium Compounds; Pain Management; Pain, Postoperative; Receptors, N-Methyl-D-Aspartate; Risk Assessment

2012

Trials

2 trial(s) available for amantadine and ketamine

ArticleYear
Ketamine induction and amantadine.
    The British journal of clinical practice, 1975, Volume: 29, Issue:1

    Topics: Adult; Amantadine; Anesthesia, General; Blood Pressure; Clinical Trials as Topic; Diazepam; Female; Humans; Ketamine; Male; Middle Aged; Psychophysiology; Respiration

1975
Sequential trial upon the awakening effect of amantadine after ketamine anaesthesia.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:11

    Topics: Adult; Amantadine; Anesthesia, Intravenous; Anesthetics, Dissociative; Clinical Trials as Topic; Humans; Injections, Intravenous; Ketamine; Male; Middle Aged; Placebos; Postoperative Care; Wakefulness

1972

Other Studies

19 other study(ies) available for amantadine and ketamine

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations

2002
Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.
    The Journal of physiology, 2007, May-15, Volume: 581, Issue:Pt 1

    Topics: Animals; Cell Line; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Xenopus laevis

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.
    European journal of medicinal chemistry, 2022, Jun-05, Volume: 236

    Topics: Alzheimer Disease; Animals; Caenorhabditis elegans; Disease Models, Animal; Memantine; Mice; Receptors, N-Methyl-D-Aspartate

2022
[Action of amantadine on arousal from balanced diazepam-ketamine anesthesia in patients undergoing angiographic examinations].
    Minerva anestesiologica, 1976, Volume: 42, Issue:9

    Topics: Amantadine; Anesthesia, General; Angiography; Aortography; Diazepam; Humans; Ketamine

1976
[Ketamine inhibits n-methyl-d-aspartate (NMDA) receptor mediated acetylcholine release from rabbit caudate nucleus slices].
    Der Anaesthesist, 1994, Volume: 43 Suppl 2

    Topics: Acetylcholine; Action Potentials; Amantadine; Animals; Caudate Nucleus; Choline; Dizocilpine Maleate; In Vitro Techniques; Ketamine; Memantine; Rabbits; Receptors, N-Methyl-D-Aspartate; Valine

1994
Comparative patch-clamp studies with freshly dissociated rat hippocampal and striatal neurons on the NMDA receptor antagonistic effects of amantadine and memantine.
    The European journal of neuroscience, 1996, Volume: 8, Issue:3

    Topics: Amantadine; Animals; Dose-Response Relationship, Drug; Hippocampus; Ketamine; Memantine; Membrane Potentials; N-Methylaspartate; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1996
Investigation on possible antioxidative properties of the NMDA-receptor antagonists ketamine, memantine, and amantadine in comparison to nicanartine in vitro.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1998, Volume: 50, Issue:4-6

    Topics: 7-Alkoxycoumarin O-Dealkylase; Amantadine; Animals; Antioxidants; Antiparkinson Agents; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hydrogen Peroxide; Ketamine; Lipid Peroxidation; Male; Memantine; Microsomes, Liver; Pyridines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Thiobarbituric Acid Reactive Substances

1998
Non-competitive NMDA receptor antagonists moderate seizure-induced c-fos expression in the rat cerebral cortex.
    Brain research bulletin, 2003, Feb-15, Volume: 59, Issue:6

    Topics: 4-Aminopyridine; Amantadine; Animals; Behavior, Animal; Cerebral Cortex; Dizocilpine Maleate; Dopamine Agents; Epilepsy; Excitatory Amino Acid Antagonists; Gene Expression; Hippocampus; Immunohistochemistry; Ketamine; Male; Potassium Channel Blockers; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger

2003
Survival after treatment of rabies with induction of coma.
    The New England journal of medicine, 2005, Jun-16, Volume: 352, Issue:24

    Topics: Adolescent; Amantadine; Anesthetics; Animals; Antiviral Agents; Athetosis; Benzodiazepines; Bites and Stings; Chiroptera; Chorea; Coma; Dysarthria; Female; Gait Disorders, Neurologic; Humans; Ketamine; Midazolam; Rabies; Rabies virus; Ribavirin

2005
Recovery from rabies.
    The New England journal of medicine, 2005, Jun-16, Volume: 352, Issue:24

    Topics: Amantadine; Anesthetics; Animals; Antiviral Agents; Bites and Stings; Chiroptera; Coma; Excitatory Amino Acid Antagonists; Humans; Ketamine; Midazolam; Rabies; Rabies Vaccines; Survivors

2005
Combined therapy with clonidine and amantadine may act in two stages of glutamate-mediated neuropathic pain caused by a needle puncture in an upper extremity.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Analgesics, Non-Narcotic; Calcium Channel Blockers; Catheterization, Peripheral; Clonidine; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Ketamine; Median Nerve; Pain; Peripheral Nervous System Diseases; Receptors, N-Methyl-D-Aspartate

2005
Applying the Milwaukee protocol to treat canine rabies in Equatorial Guinea.
    Scandinavian journal of infectious diseases, 2009, Volume: 41, Issue:5

    Topics: Amantadine; Anesthetics, Dissociative; Animals; Antiviral Agents; Child, Preschool; Combined Modality Therapy; Dogs; Drug Therapy, Combination; Equatorial Guinea; Fatal Outcome; Humans; Ketamine; Male; Midazolam; Rabies; Rabies virus; Ribavirin; Treatment Outcome; Ubiquinone

2009
Therapy of rabies encephalitis.
    Biomedica : revista del Instituto Nacional de Salud, 2009, Volume: 29, Issue:2

    Topics: Adolescent; Amantadine; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Chiroptera; Clinical Protocols; Combined Modality Therapy; Deep Sedation; Electroencephalography; Encephalitis, Viral; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Midazolam; Phenobarbital; Rabies; Rabies virus; Ribavirin

2009
Association between NMDAR antagonists, drug abuse and dependence: A disproportionality analysis from the WHO pharmacovigilance database.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:11

    Topics: Amantadine; Analgesics; Bayes Theorem; Dextromethorphan; Humans; Ketamine; Memantine; Pharmacovigilance; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders; World Health Organization

2022