Compounds > amantadine

amantadine and dimyristoylphosphatidylcholine

amantadine has been researched along with dimyristoylphosphatidylcholine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's4 (50.00)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Broadhurst, RW; Hansen, RK; Kolocouris, A1
Cross, TA; Hu, J; Li, C; Yi, M; Zhou, HX1
Cady, SD; Degrado, WF; Hong, M; Schmidt-Rohr, K; Soto, CS; Wang, J1
Altamirano, M; Dukes, N; Jemiola-Rzeminska, M; Strzalka, K; Suwalsky, M; Villena, F1
Gauglitz, G; Gohlke, H; Homeyer, N; Ioannidis, H; Kolarov, F; Kolocouris, A; Zikos, C1
Amentisch, H; Chountoulesi, M; Demetzos, C; Kiriakidi, S; Kolocouris, A; Kolokouris, D; Konstantinidi, A; Mali, G; Mavromoustakos, T; Naziris, N; Ntountaniotis, D; Sartori, B1
Amenitsch, H; Busath, DD; Čendak, T; Chountoulesi, M; Demetzos, C; Kolocouris, A; Konstantinidi, A; Mali, G; Mavromoustakos, T; Naziris, N; Plakantonaki, M; Sartori, B; Triantafyllakou, I; Tselios, T1
Dregni, AJ; Hong, M; Kolocouris, A; Mandala, VS; McKay, MJ; Shcherbakov, AA1

Other Studies

8 other study(ies) available for amantadine and dimyristoylphosphatidylcholine

ArticleYear
Interaction between an amantadine analogue and the transmembrane portion of the influenza A M2 protein in liposomes probed by 1H NMR spectroscopy of the ligand.
    Journal of medicinal chemistry, 2004, Sep-23, Volume: 47, Issue:20

    Topics: Amantadine; Amino Acid Sequence; Antiviral Agents; Cell Membrane; Dimyristoylphosphatidylcholine; Hydrogen-Ion Concentration; Ligands; Liposomes; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Protein Structure, Tertiary; Viral Matrix Proteins

2004
Solid-state NMR and MD simulations of the antiviral drug amantadine solubilized in DMPC bilayers.
    Biophysical journal, 2008, Feb-15, Volume: 94, Issue:4

    Topics: Amantadine; Antiviral Agents; Computer Simulation; Dimyristoylphosphatidylcholine; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Fluidity; Models, Chemical; Models, Molecular; Molecular Conformation; Porosity; Solubility

2008
Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers.
    Nature, 2010, Feb-04, Volume: 463, Issue:7281

    Topics: Amantadine; Amino Acid Sequence; Antiviral Agents; Binding Sites; Crystallography, X-Ray; Dimyristoylphosphatidylcholine; Hydrogen-Ion Concentration; Influenza A virus; Lipid Bilayers; Models, Molecular; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Protein Conformation; Structure-Activity Relationship; Temperature; Viral Matrix Proteins

2010
Interactions of the antiviral and antiparkinson agent amantadine with lipid membranes and human erythrocytes.
    Biophysical chemistry, 2015, Volume: 202

    Topics: Amantadine; Antiparkinson Agents; Antiviral Agents; Cell Membrane; Cell Shape; Dimyristoylphosphatidylcholine; Dose-Response Relationship, Drug; Erythrocytes; Humans; Lipid Bilayers; Microscopy, Electron, Scanning; Models, Molecular; Molecular Structure; Phosphatidylethanolamines; Structure-Activity Relationship

2015
Interpreting Thermodynamic Profiles of Aminoadamantane Compounds Inhibiting the M2 Proton Channel of Influenza A by Free Energy Calculations.
    Journal of chemical information and modeling, 2016, Jan-25, Volume: 56, Issue:1

    Topics: Amantadine; Amino Acid Sequence; Antiviral Agents; Apoproteins; Biological Transport; Cell Membrane; Dimyristoylphosphatidylcholine; Drug Design; Hydrogen-Ion Concentration; Influenza A virus; Ligands; Lipid Bilayers; Membrane Proteins; Molecular Dynamics Simulation; Molecular Sequence Data; Protein Multimerization; Protein Stability; Protein Structure, Quaternary; Protein Structure, Tertiary; Protons; Thermodynamics; Viral Proteins

2016
Comparative Perturbation Effects Exerted by the Influenza A M2 WT Protein Inhibitors Amantadine and the Spiro[pyrrolidine-2,2'-adamantane] Variant AK13 to Membrane Bilayers Studied Using Biophysical Experiments and Molecular Dynamics Simulations.
    The journal of physical chemistry. B, 2018, 11-01, Volume: 122, Issue:43

    Topics: Adamantane; Amantadine; Binding Sites; Calorimetry, Differential Scanning; Dimyristoylphosphatidylcholine; Influenza A virus; Lipid Bilayers; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Scattering, Small Angle; Viral Matrix Proteins; X-Ray Diffraction

2018
The boundary lipid around DMPC-spanning influenza A M2 transmembrane domain channels: Its structure and potential for drug accommodation.
    Biochimica et biophysica acta. Biomembranes, 2020, 03-01, Volume: 1862, Issue:3

    Topics: Amantadine; Antiviral Agents; Binding Sites; Dimyristoylphosphatidylcholine; Humans; Influenza A virus; Influenza, Human; Ligands; Lipid Bilayers; Molecular Dynamics Simulation; Protein Domains; Scattering, Small Angle; Viral Matrix Proteins; X-Ray Diffraction

2020
Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers.
    Nature structural & molecular biology, 2020, Volume: 27, Issue:12

    Topics: Amantadine; Amiloride; Antiviral Agents; Coronavirus Envelope Proteins; Dimyristoylphosphatidylcholine; Hydrogen-Ion Concentration; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylalanine; Phospholipids; Protein Conformation; Protein Domains; SARS-CoV-2

2020