amantadine and dextromethorphan

amantadine has been researched along with dextromethorphan in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's6 (46.15)29.6817
2010's4 (30.77)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Almonte, A; Balster, R; Barber, J; Dravid, SM; Erreger, K; French, A; Le, P; Lyuboslavsky, P; Mosely, C; Murray, E; Murray, TF; Nicholson, K; Traynelis, SF; Yuan, H1
Baudy, RB; Childers, WE1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blanchet, PJ; Chase, TN; Del Dotto, P; van den Munckhof, P; Verhagen Metman, L1
Balster, RL; Harvey, SA; Nicholson, KL; Wiley, JL1
Bujak-Gizycka, B; Korbut, R; Madej, J; Olszanecki, R; Suski, M1
Berger, SP; Giuffrida, A; Johnson, SW; Macheda, T; Martinez, AA; Meshul, CK; Paquette, MA1
Fouilhé Sam-Laï, N; Jouanjus, E; Lapeyre-Mestre, M; Revol, B1

Reviews

2 review(s) available for amantadine and dextromethorphan

ArticleYear
N-methyl-D-aspartate antagonists and neuropathic pain: the search for relief.
    Journal of medicinal chemistry, 2007, May-31, Volume: 50, Issue:11

    Topics: Analgesics; Analgesics, Opioid; Animals; Binding Sites; Glycine; Humans; Ion Channel Gating; Pain; Peripheral Nervous System Diseases; Protein Subunits; Receptors, N-Methyl-D-Aspartate

2007
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

11 other study(ies) available for amantadine and dextromethorphan

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.
    The Journal of physiology, 2007, May-15, Volume: 581, Issue:Pt 1

    Topics: Animals; Cell Line; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Xenopus laevis

2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Blockade of glutamatergic transmission as treatment for dyskinesias and motor fluctuations in Parkinson's disease.
    Amino acids, 1998, Volume: 14, Issue:1-3

    Topics: Amantadine; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Dextromethorphan; Dextrorphan; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Levodopa; Movement Disorders; Parkinson Disease; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate

1998
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats.
    Psychopharmacology, 2003, Volume: 165, Issue:4

    Topics: Acoustic Stimulation; Adrenergic Uptake Inhibitors; Alanine; Amantadine; Animals; Binding Sites; Desipramine; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ibogaine; Loudness Perception; Male; Memantine; Muscarinic Antagonists; Neural Inhibition; Orphenadrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Selective Serotonin Reuptake Inhibitors

2003
[Evaluation of morphine metabolism in presence of amantadine and dextromethorphan in human serum by high performance liquid chromatography coupled with mass spectrometry (LC/MS) method].
    Folia medica Cracoviensia, 2008, Volume: 49, Issue:3-4

    Topics: Amantadine; Analgesics, Non-Narcotic; Analgesics, Opioid; Chromatography, High Pressure Liquid; Dextromethorphan; Dose-Response Relationship, Drug; Drug Interactions; Humans; Mass Spectrometry; Morphine; Pain; Pain Threshold

2008
Anti-dyskinetic mechanisms of amantadine and dextromethorphan in the 6-OHDA rat model of Parkinson's disease: role of NMDA vs. 5-HT1A receptors.
    The European journal of neuroscience, 2012, Volume: 36, Issue:9

    Topics: Amantadine; Animals; Antiparkinson Agents; Cycloserine; Dextromethorphan; Dopamine Agents; Dyskinesias; Levodopa; Male; Oxidopamine; Parkinsonian Disorders; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists

2012
Association between NMDAR antagonists, drug abuse and dependence: A disproportionality analysis from the WHO pharmacovigilance database.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:11

    Topics: Amantadine; Analgesics; Bayes Theorem; Dextromethorphan; Humans; Ketamine; Memantine; Pharmacovigilance; Receptors, N-Methyl-D-Aspartate; Substance-Related Disorders; World Health Organization

2022