amantadine and benztropine

amantadine has been researched along with benztropine in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	30 (81.08)	18.7374
1990's	1 (2.70)	18.2507
2000's	3 (8.11)	29.6817
2010's	3 (8.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Bernardo, DL; DiMascio, A; Greenblatt, DJ; Marder, JE	2
Carroll, BJ; Curtis, GC; Kokmen, E	1
Daniel Falcón, H	1
Postma, JU; Van Tilburg, W	1
Ananth, J; Noonan, JP; Sangani, H	1
Taylor, J	1
Butzer, JF; Sahs, AL; Silver, DE	1
Bergen, D; Goetz, C; Klawans, HL	1
Barnett, A; Goldstein, J	1
Barnett, A; Goldstein, JM; Malick, JB	1
Dandiya, PC; Kulkarni, SK	1
Parkenberg, H	1
Brotman, AW; Falk, WE; Galvin-Nadeau, M; Gelenberg, AJ; Lavori, PW; Marder, S; Mohs, RC; Spring, B; Van Putten, T; Wojcik, JD	1
Dougan, DF; Duffield, P; Wade, DN	1
Craft, RB; Fallon, J; Hitri, A; Sethi, R; Sinha, D	1
Freter, S; McCue, M; McEvoy, JP	1
McEvoy, JP	1
Craft, RB; Hitri, A; Sethi, R; Sinha, D	1
Brotman, AW; Falk, WE; Gelenberg, AJ; Lavori, PW; Marder, SR; Mohs, RC; Spring, B; Van Putten, T	1
Merrick, EM; Schmitt, PP	1
Wanger, SL	1
Benesová, O	1
Abuzzahab, FS; Kelly, JT; Schiele, BC; Zimmermann, RL	1
Barnett, A; Fiore, JW	1
Cashin, CH; Sutton, S	1
Chase, TN; Glaubiger, GA; Woods, AC	1
Borison, RL; Diamond, BI	1
Ang, L; Borison, RL; Davis, JM; Diamond, BI; Hamilton, WJ	1
Ang, L; Borison, RL; Chang, S; Comaty, JE; Davis, JM; Dysken, M	1
Gordon, I; Rehavi, M; Weizman, R	1

Reviews

3 review(s) available for amantadine and benztropine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The management of Parkinson's syndrome. The Medical clinics of North America, 1972, Volume: 56, Issue:3 Topics: Adult; Aged; Amantadine; Benztropine; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Middle Aged; Parasympatholytics; Parkinson Disease; Physical Therapy Modalities; Psychotherapy; Stereotaxic Techniques; Thalamus; Thinking	1972
[Review of current pharmacotherapy of Parkinsonism. Comprehensive review]. Ceskoslovenska neurologie, 1973, Volume: 36, Issue:3 Topics: 5-Hydroxytryptophan; Amantadine; Anticonvulsants; Apomorphine; Benztropine; Carboxy-Lyases; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Humans; Parasympatholytics; Parkinson Disease; Procyclidine; Trihexyphenidyl	1973

Trials

14 trial(s) available for amantadine and benztropine

Article	Year
A controlled trial of amantadine in drug-induced extrapyramidal disorders. Archives of general psychiatry, 1976, Volume: 33, Issue:5 Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Drug Evaluation; Humans; Schizophrenia	1976
A controlled trial of amantadine in drug-induced extrapyramidal disorders. Psychopharmacology bulletin, 1977, Volume: 13, Issue:3 Topics: Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male	1977
Amantadine in drug-induced extrapyramidal signs: a comparative study. International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:4 Topics: Adult; Aged; Amantadine; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Phenothiazines; Tranquilizing Agents	1975
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up. Neurology, 1975, Volume: 25, Issue:7 Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Female; Follow-Up Studies; Humans; Locomotion; Long-Term Care; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Procyclidine; Time Factors; Tremor; Trihexyphenidyl	1975
Anticholinergic effects on memory: benztropine versus amantadine. Journal of clinical psychopharmacology, 1989, Volume: 9, Issue:3 Topics: Adolescent; Adult; Affect; Amantadine; Arousal; Attention; Benztropine; Brain; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Memory; Mental Recall; Middle Aged; Random Allocation; Receptors, Cholinergic; Retention, Psychology; Salivation; Serial Learning; Tropanes	1989
Serum neuroleptic and anticholinergic activity in relationship to cognitive toxicity of antiparkinsonian agents in schizophrenic patients. Psychopharmacology bulletin, 1987, Volume: 23, Issue:1 Topics: Adult; Amantadine; Antipsychotic Agents; Benztropine; Drug Interactions; Humans; Male; Memory; Middle Aged; Schizophrenia; Trihexyphenidyl; Tropanes	1987
Replacement of chronically administered anticholinergic drugs by amantadine in outpatient management of chronic schizophrenia. Clinical therapeutics, 1987, Volume: 9, Issue:4 Topics: Adult; Amantadine; Antipsychotic Agents; Benztropine; Chronic Disease; Dyskinesia, Drug-Induced; Female; Humans; Male; Memory; Mental Recall; Middle Aged; Schizophrenia; Schizophrenic Psychology; Tropanes; Verbal Learning	1987
A double-blind crossover comparison of antiparkinson drug therapy: amantadine versus anticholinergics in 90 normal volunteers, with an emphasis on differential effects on memory function. The Journal of clinical psychiatry, 1987, Volume: 48 Suppl Topics: Adult; Age Factors; Aged; Amantadine; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Double-Blind Method; Emotions; Female; Humans; Male; Memory; Memory Disorders; Middle Aged; Trihexyphenidyl; Tropanes	1987
Anticholinergic effects on memory: benztropine vs. amantadine. Psychopharmacology bulletin, 1987, Volume: 23, Issue:1 Topics: Adult; Amantadine; Benztropine; Emotions; Female; Humans; Male; Memory; Time Perception; Tropanes	1987
A controlled study of the clinical effects of amantadine hydrochloride (Symmetrel). Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:8 Topics: Adult; Amantadine; Basal Ganglia Diseases; Benztropine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease; Placebos	1973
A double-blind study of amantadine hydrochloride versus benztropine mesylate in drug-induced parkinsonism. Pharmacology, 1974, Volume: 12, Issue:2 Topics: Administration, Oral; Amantadine; Antiparkinson Agents; Benztropine; Capsules; Chlorpromazine; Clinical Trials as Topic; Humans; Parkinson Disease; Parkinson Disease, Secondary; Placebos; Schizophrenia; Time Factors	1974
Parkinson disease treated with a suspected dopamine receptor agonist. Archives of neurology, 1974, Volume: 30, Issue:5 Topics: Adult; Aged; Amantadine; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Piperazines; Placebos; Probenecid; Pyrimidines; Receptors, Cholinergic; Tremor; Trihexyphenidyl	1974
Treatment approaches in Gilles de la Tourette syndrome. Brain research bulletin, 1983, Volume: 11, Issue:2 Topics: Amantadine; Benztropine; Clonidine; Fluphenazine; Haloperidol; Humans; Lithium; Tourette Syndrome; Trifluoperazine	1983
New pharmacological approaches in the treatment of Tourette syndrome. Advances in neurology, 1982, Volume: 35 Topics: Adolescent; Adult; Amantadine; Benztropine; Child; Clinical Trials as Topic; Clonidine; Female; Fluphenazine; Haloperidol; Humans; Lithium; Male; Tourette Syndrome; Trifluoperazine	1982

Other Studies

20 other study(ies) available for amantadine and benztropine

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Paradoxical response to dopamine agonists in tardive dyskinesia. The American journal of psychiatry, 1977, Volume: 134, Issue:7 Topics: Adrenergic alpha-Agonists; Adult; Amantadine; Apomorphine; Benztropine; Clozapine; Deanol; Dextroamphetamine; Dose-Response Relationship, Drug; Drug Antagonism; Drug Tolerance; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Levodopa; Physostigmine; Receptors, Dopamine; Reserpine; Stimulation, Chemical; Thioridazine	1977
[Collateral effects of antiparkinsonian agents used in psychiatry]. Neurologia, neurocirugia, psiquiatria, 1976, Volume: 17, Issue:1 Topics: Amantadine; Antiparkinson Agents; Atropine; Atropine Derivatives; Benztropine; Brain; Histamine H1 Antagonists; Humans; Phenothiazines; Respiration; Scopolamine	1976
Visual hallucinations and delirium during treatment with amantadine (Symmetrel). Journal of the American Geriatrics Society, 1975, Volume: 23, Issue:5 Topics: Aged; Amantadine; Benztropine; Biperiden; Delirium; Drug Eruptions; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Orphenadrine; Parkinson Disease	1975
Parkinson's disease. The Australian nurses' journal. Royal Australian Nursing Federation, 1977, Volume: 7, Issue:5 Topics: Amantadine; Benztropine; Humans; Levodopa; Parkinson Disease; Procyclidine; Trihexyphenidyl	1977
Levodopa-induced myoclonus. Archives of neurology, 1975, Volume: 32, Issue:5 Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; Levodopa; Male; Methysergide; Middle Aged; Movement Disorders; Myoclonus; Parkinson Disease; Propranolol; Serotonin; Serotonin Antagonists; Sleep; Trihexyphenidyl	1975
Head-turning induced by electrical stimulation of the caudate nucleus and its antagonism by anti-parkinson drugs. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 194, Issue:2 Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Behavior, Animal; Benztropine; Caudate Nucleus; Depression, Chemical; Electric Stimulation; Humans; Levodopa; Male; Rats; Stereotyped Behavior; Trihexyphenidyl	1975
The evaluation of anti-parkinson drugs on reserpine-induced rigidity in rats. European journal of pharmacology, 1975, Volume: 33, Issue:1 Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Carbidopa; Hindlimb; Levodopa; Male; Methamphetamine; Muscle Rigidity; Rats; Reserpine; Scopolamine; Time Factors; Trihexyphenidyl	1975
Influence of chemical stimulation of central dopaminergic system on the open field behaviour of rats. Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1975, Volume: 8, Issue:1 Topics: Amantadine; Amphetamine; Animals; Apomorphine; Behavior, Animal; Benztropine; Brain; Dopamine; Levodopa; Male; Rats; Stimulation, Chemical	1975
[Treatment of parkinsonism]. Ugeskrift for laeger, 1976, Apr-26, Volume: 138, Issue:18 Topics: Amantadine; Benztropine; Biperiden; Humans; Levodopa; Orphenadrine; Parkinson Disease; Procyclidine; Trihexyphenidyl	1976
Modulation of dopamine receptors in the Tapes clam by dextroamphetamine and phenylethanolamine. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1987, Volume: 86, Issue:2 Topics: Adenosine Monophosphate; Amantadine; Animals; Benztropine; Bivalvia; Chlorphenamidine; Clozapine; Cocaine; Dextroamphetamine; Dopamine; Ethanolamines; Heart Rate; Myocardial Contraction; Receptors, Dopamine; Serotonin; Tetrahydronaphthalenes	1987
Drug levels and antiparkinsonian drugs in neuroleptic-treated schizophrenic patients. Clinical neuropharmacology, 1987, Volume: 10, Issue:3 Topics: Adult; Amantadine; Antiparkinson Agents; Antipsychotic Agents; Basal Ganglia Diseases; Benztropine; Drug Therapy, Combination; Humans; Intestinal Absorption; Male; Middle Aged; Radioligand Assay; Schizophrenia; Trihexyphenidyl	1987
The effect of antiparkinson drugs on the liguomandibular reflex in cats. European journal of pharmacology, 1973, Volume: 21, Issue:2 Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Benztropine; Cats; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Haloperidol; Lingual Nerve; Mandibular Nerve; Phenoxybenzamine; Receptors, Drug; Reflex	1973
The effect of anti-Parkinson drugs on catalepsy induced by -methyl-p-tyrosine in rats pretreated with intraventricular 6-hydroxydopamine. British journal of pharmacology, 1973, Volume: 47, Issue:3 Topics: Amantadine; Amphetamine; Animals; Antiparkinson Agents; Apomorphine; Benserazide; Benztropine; Brain Chemistry; Catalepsy; Dextroamphetamine; Dihydroxyphenylalanine; Humans; Hydroxydopamines; Methylphenidate; Methyltyrosines; Rats; Reserpine; Scopolamine	1973
Anticholinergics promote neuroleptic-induced tardive dyskinesia. Advances in biochemical psychopharmacology, 1980, Volume: 24 Topics: Amantadine; Animals; Antipsychotic Agents; Benztropine; Dextroamphetamine; Drug Synergism; Dyskinesia, Drug-Induced; Haloperidol; Humans; Male; Motor Activity; Parasympatholytics; Rats; Stereotyped Behavior	1980
Modulatory effect of agents active in the presynaptic dopaminergic system on the striatal dopamine transporter. European journal of pharmacology, 1996, Feb-29, Volume: 298, Issue:1 Topics: Amantadine; Animals; Benztropine; Carrier Proteins; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Levodopa; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Reserpine	1996