amantadine and atropine

amantadine has been researched along with atropine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199017 (45.95)18.7374
1990's3 (8.11)18.2507
2000's9 (24.32)29.6817
2010's7 (18.92)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Dekker, TG; Fourie, TG; Oliver, DW; Snyckers, FO1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Daniel Falcón, H1
Borsy, J; Dunai-Kovács, Z; Székely, JI1
Bermanzohn, PC; Lipper, S1
Onodera, K; Shinoda, H1
Gupta, RC; Kadel, WL1
Bianchi, C; Tomasi, L1
Gressier, H; Malecot, E; Poignant, JC1
Costall, B; Naylor, RJ1
Shibasaki, H1
Dulska, E; Lacki, M; Wolfarth, S1
Grossmann, W; Jurna, I; Nell, T; Ruzdić, N1
Ahtee, L; Kääriäinen, I; Paasonen, MK1
Cates, LA; Cramer, MB; Gallio, RL1
Florio, V; Longo, VG1
Clark, R; Grelak, RP; Stump, JM; Vernier, VG1
Link, F1
Manten, A1
Fincke, M; Gothóni, P; Lehtinen, M1
Ferraz, MR; Santos, R1
Adotevi, N; Dabrowska, N; Joshi, S; Kapur, J; Lewczuk, E; Shan, S; Sun, H; Williamson, J1

Reviews

2 review(s) available for amantadine and atropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Parkinson's syndrome. Recent progress in the medical treatment and its pharmacological basis.
    Minnesota medicine, 1971, Volume: 54, Issue:10

    Topics: Amantadine; Atropine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parkinson Disease; Tryptophan

1971

Other Studies

35 other study(ies) available for amantadine and atropine

ArticleYear
Synthesis and biological activity of D3-trishomocubyl-4-amines.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:2

    Topics: Animals; Antiparkinson Agents; Bridged-Ring Compounds; Catalepsy; Chemical Phenomena; Chemistry; Male; Mice; Stereoisomerism; Structure-Activity Relationship

1991
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Collateral effects of antiparkinsonian agents used in psychiatry].
    Neurologia, neurocirugia, psiquiatria, 1976, Volume: 17, Issue:1

    Topics: Amantadine; Antiparkinson Agents; Atropine; Atropine Derivatives; Benztropine; Brain; Histamine H1 Antagonists; Humans; Phenothiazines; Respiration; Scopolamine

1976
The effect of anti-parkinsonian drugs on chlorpromazine-induced depression of operant behaviour.
    Pharmacology, 1976, Volume: 14, Issue:3

    Topics: Amantadine; Animals; Antiparkinson Agents; Apomorphine; Atropine; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Phenothiazines; Rats; Trihexyphenidyl

1976
Letter: Electroconvulsive therapy in patients with parkinsonism.
    The American journal of psychiatry, 1975, Volume: 132, Issue:4

    Topics: Amantadine; Atropine; Depression; Diphenhydramine; Electroconvulsive Therapy; Female; Humans; Levodopa; Methohexital; Middle Aged; Parkinson Disease; Succinylcholine; Suicide

1975
Pharmacological characteristics of catalepsy induced by intracerebroventricular administration of histamine in mice: the importance of muscarinic step in central cholinergic neurons.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Amantadine; Animals; Atropine; Biperiden; Bromocriptine; Catalepsy; Histamine; Injections, Intraventricular; Levodopa; Male; Mice; Neurons; Promethazine; Receptors, Muscarinic; Scopolamine; Trihexyphenidyl

1991
Prevention and antagonism of acute carbofuran intoxication by memantine and atropine.
    Journal of toxicology and environmental health, 1989, Volume: 28, Issue:1

    Topics: Acetylcholinesterase; Amantadine; Animals; Atropine; Carbofuran; Carboxylesterase; Carboxylic Ester Hydrolases; Chemical Phenomena; Chemistry; Cholinesterase Inhibitors; Drug Antagonism; Drug Synergism; Insecticides; Male; Memantine; Rats; Rats, Inbred Strains

1989
Central nervous system and autonomic nervous system effects of amantadine and of some standard anti-Parkinson drugs.
    Pharmacology, 1973, Volume: 10, Issue:4

    Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Autonomic Nervous System; Body Temperature; Carbachol; Central Nervous System; Dihydroxyphenylalanine; Drug Interactions; Gastrointestinal Motility; Male; Mecamylamine; Mice; Mydriatics; Nicotine; Oxotremorine; Phenothiazines; Pupil; Rats; Trihexyphenidyl

1973
Comparative effects of apomorphine, piribedil and other neurotropic agents on central analgesic-induced catatonia in the rat.
    European journal of pharmacology, 1974, Volume: 29, Issue:1

    Topics: Amantadine; Analgesics, Opioid; Animals; Antiparkinson Agents; Apomorphine; Atropine; Benserazide; Benzyl Compounds; Catatonia; Dextroamphetamine; Dextromoramide; Dihydroxyphenylalanine; Dioxoles; Dose-Response Relationship, Drug; Humans; Male; Morphine; Piperazines; Pyrimidines; Rats; Time Factors; Trihexyphenidyl

1974
Dopamine agonist and antagonist activities of piribedil (ET495)and its metabolites.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:1

    Topics: Amantadine; Amphetamine; Animals; Apomorphine; Atropine; Behavior, Animal; Caudate Nucleus; Dextroamphetamine; Dioxoles; Dopamine; Dopamine Antagonists; Drug Synergism; Haloperidol; Humans; Injections; Male; Methylphenidate; Motor Activity; Nialamide; Piperazines; Pyrimidines; Rats; Stereotyped Behavior; Sulfites

1974
Comparison of the effects of the intranigral injections of cholinomimetics with systemic injections of the dopamine receptor stimulating and blocking agents in the rabbit.
    Neuropharmacology, 1974, Volume: 13, Issue:9

    Topics: Acetylcholine; Amantadine; Animals; Apomorphine; Atropine; Caudate Nucleus; Cerebral Cortex; Depression, Chemical; Electrodes, Implanted; Electroencephalography; Hippocampus; Humans; Injections; Locomotion; Methacholine Compounds; Neostigmine; Parasympathomimetics; Rabbits; Receptors, Cholinergic; Spirostans; Stereotyped Behavior; Stimulation, Chemical; Substantia Nigra; Time Factors

1974
The effect of -methyl-p-tyrosine and substantia nigra lesions on spinal motor activity in the rat.
    European journal of pharmacology, 1972, Volume: 20, Issue:3

    Topics: Action Potentials; Amantadine; Animals; Atropine; Dihydroxyphenylalanine; Electrocoagulation; Electromyography; Hydroxydopamines; Methamphetamine; Methyltyrosines; Microinjections; Motor Activity; Motor Neurons; Rats; Reflex; Spinal Nerves; Substantia Nigra

1972
Effect of nalorphine and antiparkinsonian drugs on methadone-induced rigidity; relation to homovanillic acid content of nucleus caudatus.
    Annales medicinae experimentalis et biologiae Fenniae, 1972, Volume: 50, Issue:4

    Topics: Amantadine; Animals; Atropine; Body Temperature; Brain; Caudate Nucleus; Depression, Chemical; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methadone; Muscle Rigidity; Muscle Tonus; Nalorphine; Parasympatholytics; Phenylacetates; Rats; Serotonin; Spectrometry, Fluorescence; Trihexyphenidyl

1972
Phosphorus--nitrogen compounds. XV. N-1-adamantylphosphoramidic dichloride and dimethyl and diphenyl N-1-adamantylphosphoramidate.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:10

    Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Guinea Pigs; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Motor Activity; Organophosphorus Compounds; Oxotremorine; Perphenazine; Spectrophotometry, Infrared; Tremorine

1973
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
    Physiology & behavior, 1971, Volume: 6, Issue:4

    Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl

1971
Amantadine-dopamine interaction: possible mode of action in Parkinsonism.
    Science (New York, N.Y.), 1970, Jul-10, Volume: 169, Issue:3941

    Topics: Acetylcholine; Amantadine; Animals; Atropine; Dogs; Dopamine; Neurons; Parkinson Disease; Stimulation, Chemical; Vagotomy

1970
[Chemotherapy of viral diseases].
    Schweizerische medizinische Wochenschrift, 1967, Jul-01, Volume: 97, Issue:26

    Topics: Amantadine; Antiviral Agents; Atropine; Biguanides; Humans; Idoxuridine; Scopolamine; Thiosemicarbazones; Virus Diseases

1967
[Chemoprofylaxis of influenza].
    Nederlands tijdschrift voor geneeskunde, 1968, Jun-22, Volume: 112, Issue:25

    Topics: Amantadine; Animals; Antiviral Agents; Atropine; Biguanides; Humans; Influenza, Human; Mice; Scopolamine

1968
Drugs for Parkinson's disease reduce tremor induced by physostigmine.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 323, Issue:3

    Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Biperiden; Bromocriptine; Male; Physostigmine; Pimozide; Rats; Rats, Inbred Strains; Tremor

1983
Amantadine stimulates sexual behavior in male rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 51, Issue:4

    Topics: Amantadine; Animals; Atropine; Copulation; Cordotomy; Ejaculation; Haloperidol; Male; Penile Erection; Rats; Rats, Wistar; Sexual Behavior, Animal; Stimulation, Chemical

1995
α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid Receptor Plasticity Sustains Severe, Fatal Status Epilepticus.
    Annals of neurology, 2020, Volume: 87, Issue:1

    Topics: Adamantane; Amantadine; Animals; Atropine; CA1 Region, Hippocampal; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gene Knockdown Techniques; Hippocampus; Male; Mice; Mice, Knockout; Neuronal Plasticity; Receptors, AMPA; Status Epilepticus; Synaptic Transmission

2020