am 580 and tretinoin

am 580 has been researched along with tretinoin in 57 studies

Research

Studies (57)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (3.51)	18.7374
1990's	14 (24.56)	18.2507
2000's	26 (45.61)	29.6817
2010's	15 (26.32)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Himi, T; Kagechika, H; Kawachi, E; Shudo, K	1
Hashimoto, Y; Himi, T; Kagechika, H; Kawachi, E; Shudo, K	1
Chandraratna, RA; Duong, TT; Klein, ES; Pino, ME; Teng, M	1
Beard, RL; Chandraratna, RA; Duong, TT; Klein, ES; Standevan, AM; Teng, M	1
Brann, MR; Currier, E; Eeg, A; Gauthier, NK; Hacksell, U; Lund, BW; Olsson, R; Piu, F; Sherbukhin, V	1
Bradley, KA; Damoiseaux, R; Gillespie, EJ; Huang, J; Manchester, M; Rogers, J; Sanchez, AM; Saxe, JP; Thomas, D	1
Charton, J; Deprez, B; Deprez-Poulain, R; Hennuyer, N; Staels, B; Tailleux, A	1
Begtrup, M; Gauthier, NK; Hacksell, U; Knapp, AE; Lund, BW; Olsson, R; Piu, F	1
Adams, DR; Barlow, S; Borthwick, AD; Brown, JT; Clarke, E; Corcoran, JPT; Goncalves, MB; Jarvis, CI; Kalindjian, SB; Miller, I; Ravier, E; Shiers, JJ; Smith, V; Taddei, DMA	1
Bauer, F; Bluethmann, H; Hoffmann, AS; Landwehr, J; LeMotte, P; Look, J	1
Hashimoto, Y; Heersche, JN; Von Schroeder, HP	1
Brooks, SC; Kazmer, S; Levin, AA; Yen, A	1
Barbui, T; Caccia, S; Garattini, E; Gianní, M; Guiso, G; Li Calzi, M; Rambaldi, A; Terao, M	1
Adamo, S; Avvisati, G; Benedetti, L; Diverio, D; Gambacorti-Passerini, C; Grignani, F; Jetten, AM; Levin, AA; Lo Coco, F; Nervi, C; Pelicci, PG; Scicchitano, BM	1
Elmazar, MM; Nau, H; Reichert, U; Shroot, B	1
Rogers, MB	1
Dawson, MI; Klaus, M; López-Boado, YS; López-Otín, C	1
Commes, T; Defacque, H; Marti, J; Piquemal, D; Rochette-Egly, C; Sévilla, C	1
Cho, Y; Talmage, DA; Tighe, AP	1
Li, Y; MacLennan, AJ; Rogers, MB	1
Bernardon, JM; Fésüs, L; Karászi, E; Michel, S; Reichert, U; Szondy, Z; Tóth, R	1
Kaiser, A; Nicke, B; Riecken, EO; Rosewicz, S; Wiedenmann, B	1
Démarchez, M; Diaz, BV; Frelin, C; Ladoux, A; Lenoir, MC; Michel, S	1
Funakoshi, Y; Ichiki, T; Ito, K; Takeda, K; Takeshita, A	1
Garattini, E; Gianni, M; Mologni, L; Ponzanelli, I; Rambaldi, A; Reichert, U; Terao, M	1
Habert, R; Livera, G; Rouiller-Fabre, V; Valla, J	1
Adam-Stitah, S; Haxsen, V; Ritz, E; Wagner, J	1
Lampen, A; Meyer, S; Nau, H	1
Devaux, Y; Grosjean, S; Latger-Cannard, V; Longrois, D; Meistelman, C; Mertes, PM; Rochette-Egly, C; Seguin-Devaux, C; Zannad, F	1
Afonja, O; Das, S; Helmer, E; Huang, A; Juste, D; Raaka, BM; Samuels, HH; Zhao, X	1
Gabriel, JL; Hutcheson, JM; Poynton, HC; Soprano, DR; Soprano, KJ; Zhang, ZP	1
Balducci, D; Bani, MR; Barbui, T; Falanga, A; Marchetti, M; Vignoli, A	1
Blomhoff, HK; Engedal, N; Ertesvag, A	1
Elmazar, MM; Nau, H	1
Kanaya, S; Kunii, R; Nemoto, E; Shibuya, N; Shimauchi, H	1
Dailloux, M; Devaux, Y; Hanriot, D; Latger-Cannard, V; Longrois, D; Mertes, PM; Seguin-Devaux, C; Zannad, F	1
Inoue, Y; Kawahara, H; Shirahata, S; Sugimoto, Y	1
Chen, Q; Ross, AC	1
Chiba, H; Kojima, T; Nishikiori, N; Ohguro, H; Osanai, M; Sawada, N	1
Chambon, P; Li, H; MacLean, G; Metzger, D; Petkovich, M	1
Chen, Q; Pai, T; Ross, AC; Zhang, Y; Zolfaghari, R	1
Hayashi, S; Ito, K; Matsumoto, M; Nagase, S; Niikura, H; Suzuki, T; Takano, T; Tamura, M; Tanabe, K; Utsunomiya, H; Yaegashi, N; Yoshinaga, K	1
Collins, G; Dawson, HD; Key, M; Pyle, R; Taub, DD	1
Ross, AC; Wu, L	1
Sirsjö, A; Törmä, H; Vahlquist, A; Virtanen, M	1
Hessel, S; Lampen, A	1
Dezsö, B; Lindstedt, M; Nagy, G; Nagy, L; Pap, A; Póliska, S; Rühl, R; Santegoets, SJ; Szanto, A; Szatmari, I; Széles, L	1
Bulun, SE; Cheng, YH; Pavone, ME; Utsunomiya, H; Yin, P	1
Abé, S; Eto, K; Honmyou, A; Kiyonari, H; Nakao, K; Zhang, J	1
Ayaori, M; Hisada, T; Iizuka, M; Ikewaki, K; Kagechika, H; Komatsu, T; Nakanishi, T; Nakaya, K; Ogura, M; Sasaki, M; Takiguchi, S; Terao, Y; Uehara, Y; Uto-Kondo, H; Yakushiji, E; Yogo, M	1
Aydemir, G; Blomhoff, R; Carlsen, H; Garcia, J; Gericke, J; Mihály, J; Rühl, R; Weiss, K	1
Clarke, E; Corcoran, JP; Deacon, R; Goncalves, MB; Hobbs, C; Jack, J; Malmqvist, T	1
Cione, E; Fletcher, S; Kane, MA; Perri, M; Yap, JL; Yu, J	1
Alberts, DS; Chen, Y; Di, PYP; Einspahr, J; Guerra, S; Krutzsch, M; Lizarraga, RE; Martinez, FD; Vasquez, MM; Zhu, L	1
Bridges, LC; Chen, J; Crouch, MJ; DeMarco, SS; Maiorana-Boutilier, AL; Peaks, MS; Phillips, CM; Shaikh, SR; Shewchuk, BM; Wang, L	1
Kimura, K; Kobayashi, M; Nishida, T; Orita, T; Sonoda, KH; Zhou, H	1
Browne, PV; Doherty, DG; Ghnewa, YG; McElligott, AM; O'Reilly, VP; Vandenberghe, E	1

Other Studies

57 other study(ies) available for am 580 and tretinoin

Article	Year
Retinobenzoic acids. 4. Conformation of aromatic amides with retinoidal activity. Importance of trans-amide structure for the activity. Journal of medicinal chemistry, 1989, Volume: 32, Issue:10 Topics: Amides; Benzoates; Cell Differentiation; Cell Line; Humans; Leukemia, Promyelocytic, Acute; Magnetic Resonance Spectroscopy; Molecular Structure; Retinoids; Structure-Activity Relationship	1989
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Amides; Binding Sites; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Molecular Structure; Retinoids; Structure-Activity Relationship	1988
Identification of a retinoic acid receptor alpha subtype specific agonist. Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16 Topics: Aminobenzoates; Animals; Benzoates; Cell Line; Dose-Response Relationship, Drug; Genes, Reporter; Molecular Structure; Protein Binding; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Transcriptional Activation; Transfection	1996
Synthesis and biological activity of retinoic acid receptor-alpha specific amides. Bioorganic & medicinal chemistry letters, 2002, Nov-04, Volume: 12, Issue:21 Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hydrogen Bonding; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; Structure-Activity Relationship	2002
Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. Journal of medicinal chemistry, 2005, Dec-01, Volume: 48, Issue:24 Topics: Administration, Oral; Animals; Benzoates; Binding Sites; Biological Availability; Biphenyl Compounds; Cells, Cultured; Humans; Models, Molecular; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, Retinoic Acid; Solubility; Structure-Activity Relationship; Thiazoles; Transcription, Genetic	2005
Amiodarone and bepridil inhibit anthrax toxin entry into host cells. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:7 Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors	2007
Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives. Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2 Topics: Carboxylic Acids; Oxadiazoles; Receptors, Retinoic Acid; Retinoids	2009
Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Cell Line, Tumor; Drug Design; Humans; Ligands; Receptors, Retinoic Acid; Structure-Activity Relationship	2009
Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist. Bioorganic & medicinal chemistry, 2018, 02-15, Volume: 26, Issue:4 Topics: Administration, Oral; Aminobenzoates; Animals; Benzoates; Cell Survival; Chlorocebus aethiops; COS Cells; Drug Design; Half-Life; Hep G2 Cells; Humans; Mice; Microsomes, Liver; Rats; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Structure-Activity Relationship; Tetrahydronaphthalenes	2018
Marked resistance of RAR gamma-deficient mice to the toxic effects of retinoic acid. The American journal of physiology, 1995, Volume: 269, Issue:1 Pt 1 Topics: Animals; Base Sequence; Benzoates; Drug Resistance; Mice; Mice, Mutant Strains; Molecular Probes; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoids; Skin; Tetrahydronaphthalenes; Tretinoin	1995
The effects of natural and synthetic retinoids on the differentiation of RCJ C5.18 chondrogenic cells. Teratology, 1994, Volume: 50, Issue:1 Topics: Animals; Benzoates; Cartilage; Cell Differentiation; Cell Line; Chalcone; Chalcones; Dose-Response Relationship, Drug; Glycosaminoglycans; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; Retinoids; Teratogens; Tetrahydronaphthalenes; Transcription Factors; Tretinoin	1994
Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor-selective retinoic acid analogs. Blood, 1996, Jan-01, Volume: 87, Issue:1 Topics: Benzoates; Cell Differentiation; Chromans; Cyclohexanes; Fatty Acids, Unsaturated; Flow Cytometry; HL-60 Cells; Humans; Ligands; Neoplasm Proteins; Pentanoic Acids; Phosphorylation; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Retinoblastoma Protein; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Substrate Specificity; Tetrahydronaphthalenes; Transcription Factors; Tretinoin	1996
AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells. Blood, 1996, Feb-15, Volume: 87, Issue:4 Topics: Alkaline Phosphatase; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents; Benzoates; Cell Differentiation; Gene Expression; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Neoplasm Proteins; Oncogene Proteins, Fusion; Receptors, Retinoic Acid; RNA, Messenger; Sialic Acid Binding Ig-like Lectin 3; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin	1996
Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase. Blood, 1996, Mar-01, Volume: 87, Issue:5 Topics: Apoptosis; Benzoates; CD18 Antigens; Cell Differentiation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytosol; Drug Resistance, Neoplasm; Enzyme Induction; Fenretinide; Gene Expression Regulation, Leukemic; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Protein Multimerization; Receptors, Retinoic Acid; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transglutaminases; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured	1996
Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma. Teratology, 1996, Volume: 53, Issue:3 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Administration, Oral; Animals; Benzoates; Bone and Bones; Central Nervous System; Digestive System Abnormalities; Female; Mice; Naphthalenes; Pregnancy; Pregnancy Outcome; Receptors, Retinoic Acid; Retinoids; Tetrahydronaphthalenes; Tretinoin; Urogenital Abnormalities	1996
Receptor-selective retinoids implicate retinoic acid receptor alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1996, Volume: 7, Issue:1 Topics: Animals; Benzoates; Blotting, Northern; Bone Morphogenetic Proteins; Bucladesine; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Growth Substances; Mice; Neoplastic Stem Cells; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Theophylline; Tretinoin	1996
Retinoic acid-induced expression of apolipoprotein D and concomitant growth arrest in human breast cancer cells are mediated through a retinoic acid receptor RARalpha-dependent signaling pathway. The Journal of biological chemistry, 1996, Dec-13, Volume: 271, Issue:50 Topics: Antineoplastic Agents; Apolipoproteins; Apolipoproteins D; Benzoates; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Morpholines; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Tretinoin	1996
Potentiation of VD-induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways. Leukemia, 1997, Volume: 11, Issue:2 Topics: Alitretinoin; Animals; Benzoates; Bexarotene; Cell Differentiation; Chromans; COS Cells; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Molecular Structure; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured; Vitamin D	1997
Retinoic acid induced growth arrest of human breast carcinoma cells requires protein kinase C alpha expression and activity. Journal of cellular physiology, 1997, Volume: 172, Issue:3 Topics: Benzoates; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Neoplasms, Hormone-Dependent; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured	1997
A putative G-protein-coupled receptor, H218, is down-regulated during the retinoic acid-induced differentiation of F9 embryonal carcinoma cells. Experimental cell research, 1998, Mar-15, Volume: 239, Issue:2 Topics: Animals; Benzoates; Bucladesine; Carcinoma, Embryonal; Cell Differentiation; Chromans; Down-Regulation; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Mice; Naphthalenes; Neoplasm Proteins; Phenotype; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured	1998
Inhibition of activation-induced apoptosis of thymocytes by all-trans- and 9-cis-retinoic acid is mediated via retinoic acid receptor alpha. The Biochemical journal, 1998, May-01, Volume: 331 ( Pt 3) Topics: Alitretinoin; Animals; Antibodies; Antigens, CD; Apoptosis; Benzoates; Cells, Cultured; DNA Fragmentation; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Protein Binding; Receptors, Antigen, T-Cell; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Thymus Gland; Transcription Factors; Tretinoin	1998
Retinoic acid receptor alpha mediates growth inhibition by retinoids in human colon carcinoma HT29 cells. Biochemical and biophysical research communications, 1999, Aug-11, Volume: 261, Issue:3 Topics: Antineoplastic Agents; Benzoates; Cell Differentiation; Cell Division; Gene Expression; HT29 Cells; Humans; Isotretinoin; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin	1999
Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids. The Journal of biological chemistry, 2000, Jan-07, Volume: 275, Issue:1 Topics: Adaptor Protein Complex 1; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Benzoates; Cells, Cultured; Endothelial Growth Factors; Humans; Keratinocytes; Lymphokines; Membrane Proteins; Mice; Mice, Nude; Naphthalenes; Protein Binding; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Skin; Skin Transplantation; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Downregulation of angiotensin II type 1 receptor by all-trans retinoic acid in vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; Benzoates; Binding, Competitive; Cells, Cultured; CREB-Binding Protein; Cycloheximide; Down-Regulation; Gene Expression Regulation; Lac Operon; Luciferases; Muscle, Smooth, Vascular; Nuclear Proteins; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Tetrahydronaphthalenes; Trans-Activators; Transcription Factors; Tretinoin	2000
Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases. Cell death and differentiation, 2000, Volume: 7, Issue:5 Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Benzoates; Caspases; Cell Differentiation; Cell Division; Enzyme Activation; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured	2000
Effects of retinoids on the meiosis in the fetal rat ovary in culture. Molecular and cellular endocrinology, 2000, Jul-25, Volume: 165, Issue:1-2 Topics: Animals; Benzoates; Female; Meiosis; Oogenesis; Organ Culture Techniques; Ovary; Rats; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; Tetrahydronaphthalenes; Tretinoin	2000
Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells. Circulation research, 2001, Mar-30, Volume: 88, Issue:6 Topics: Alitretinoin; Angiotensin II; Animals; Benzoates; Cell Division; Cells, Cultured; COS Cells; DNA; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; Luciferases; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Transcription Factor AP-1; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tretinoin	2001
Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. Biochimica et biophysica acta, 2001, Oct-31, Volume: 1521, Issue:1-3 Topics: Benzoates; Caco-2 Cells; Cytochrome P-450 Enzyme System; Docosahexaenoic Acids; Gene Expression Regulation, Enzymologic; Humans; Phytanic Acid; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Retinoid X Receptors; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Up-Regulation	2001
Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo. American journal of physiology. Endocrinology and metabolism, 2002, Volume: 283, Issue:3 Topics: Animals; Benzoates; Blood Cell Count; DNA-Binding Proteins; Enzyme Activation; Interferon Regulatory Factor-1; Interferon-gamma; Liver; Lung; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphoproteins; Rats; Rats, Inbred WKY; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Spleen; T-Lymphocyte Subsets; Tetrahydronaphthalenes; Transcription Factors; Tretinoin	2002
RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition. Oncogene, 2002, Nov-07, Volume: 21, Issue:51 Topics: Animals; Benzoates; Breast Neoplasms; Cell Cycle; Cell Division; Estradiol; Estrogens; Expressed Sequence Tags; Female; Gene Expression Regulation, Neoplastic; Gene Targeting; Genes, Dominant; Growth Substances; High Mobility Group Proteins; Humans; Kidney; Male; Mammary Glands, Animal; Mice; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Organ Specificity; Receptors, Estrogen; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoids; SOX9 Transcription Factor; Testis; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured	2002
Arginine of retinoic acid receptor beta which coordinates with the carboxyl group of retinoic acid functions independent of the amino acid residues responsible for retinoic acid receptor subtype ligand specificity. Archives of biochemistry and biophysics, 2003, Jan-15, Volume: 409, Issue:2 Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Arginine; Benzoates; Carbon Dioxide; Ligands; Mice; Models, Molecular; Mutagenesis, Site-Directed; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor gamma; Retinoids; Sensitivity and Specificity; Structure-Activity Relationship; Tetrahydronaphthalenes; Tretinoin	2003
All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties. Haematologica, 2003, Volume: 88, Issue:8 Topics: Benzoates; Capillaries; Cell Line; Cell Line, Transformed; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Fibrinolysis; Hemostasis; Humans; Plasminogen Activator Inhibitor 1; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Simian virus 40; Skin; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin; Tissue Plasminogen Activator; Tretinoin; Tumor Necrosis Factor-alpha; Umbilical Veins; Up-Regulation	2003
Survival of activated human T lymphocytes is promoted by retinoic acid via induction of IL-2. International immunology, 2004, Volume: 16, Issue:3 Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; Benzoates; Cell Survival; Cells, Cultured; DNA Fragmentation; Flow Cytometry; Humans; Interleukin-2; Lectins, C-Type; Lymphocyte Activation; Propidium; Receptors, Retinoic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Tretinoin	2004
Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands. Archives of toxicology, 2004, Volume: 78, Issue:11 Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Benzoates; Bexarotene; Dose-Response Relationship, Drug; Drug Synergism; Female; Gestational Age; Ligands; Mice; Mice, Inbred Strains; Phytanic Acid; Phytol; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Teratogens; Tetrahydronaphthalenes; Tretinoin; Vitamin A	2004
Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells. Journal of periodontal research, 2005, Volume: 40, Issue:6 Topics: Alitretinoin; Alkaline Phosphatase; Ascorbic Acid; Benzoates; Cell Differentiation; Cells, Cultured; Cementogenesis; Dexamethasone; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glycerophosphates; Humans; Isotretinoin; Periodontal Ligament; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Tretinoin	2005
Retinoic acid amplifies the host immune response to LPS through increased T lymphocytes number and LPS binding protein expression. Molecular and cellular endocrinology, 2005, Dec-21, Volume: 245, Issue:1-2 Topics: Acute-Phase Proteins; Animals; Antibodies, Bacterial; Benzoates; Carrier Proteins; Cell Proliferation; Flow Cytometry; Gene Expression Regulation; Immune System; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Listeria monocytogenes; Liver; Lymphocyte Count; Male; Membrane Glycoproteins; Nitric Oxide Synthase Type II; Rats; Rats, Inbred WKY; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tetrahydronaphthalenes; Tretinoin	2005
Retinoic acid improves a hybridoma culture in a fructose-based medium by up-regulation of fructose incorporation via retinoid nuclear receptors. Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:9 Topics: Antibodies, Monoclonal; Antibody Formation; Benzoates; Cell Growth Processes; Cell Line; Culture Media; Fructose; Glucose Transporter Type 5; Humans; Hybridomas; Lactic Acid; Methoprene; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrahydronaphthalenes; Tretinoin; Up-Regulation	2006
Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells. Experimental biology and medicine (Maywood, N.J.), 2007, Volume: 232, Issue:4 Topics: Animals; Antigen Presentation; Antigens, CD1; Antigens, CD1d; Antineoplastic Agents; Benzoates; Cell Proliferation; Dactinomycin; Galactosylceramides; Gene Expression Regulation; Glycolipids; HL-60 Cells; Humans; Killer Cells, Natural; Lymphocyte Activation; Macrophages, Peritoneal; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Response Elements; Retinoic Acid Receptor alpha; RNA, Messenger; Spleen; T-Lymphocytes; Tetrahydronaphthalenes; Transcription, Genetic; Tretinoin; U937 Cells	2007
Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. Investigative ophthalmology & visual science, 2007, Volume: 48, Issue:5 Topics: Animals; Benzoates; Calcium; Calpain; Cataract; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Lens, Crystalline; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin	2007
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology, 2007, Volume: 148, Issue:10 Topics: Animals; Apoptosis; Benzoates; Cytochrome P-450 Enzyme System; Drug Resistance; Embryo, Mammalian; Leydig Cells; Male; Meiosis; Mice; Mice, Knockout; Retinoic Acid 4-Hydroxylase; Retinoids; Sertoli Cells; Spermatozoa; Testis; Tetrahydronaphthalenes; Tretinoin	2007
Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells. Biochemistry, 2007, Dec-25, Volume: 46, Issue:51 Topics: Benzoates; Cell Line; Galactose; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Myeloid Cells; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Tetrahydronaphthalenes; Time Factors; Tretinoin; Up-Regulation	2007
Expression of retinoic acid receptors in human endometrial carcinoma. Cancer science, 2008, Volume: 99, Issue:2 Topics: Antineoplastic Agents; Benzoates; Carcinoma; Cell Proliferation; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Gene Expression; Humans; Receptors, Retinoic Acid; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured	2008
The Retinoic Acid Receptor-alpha mediates human T-cell activation and Th2 cytokine and chemokine production. BMC immunology, 2008, Apr-16, Volume: 9 Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Agents; Benzoates; Cell Differentiation; Chromans; Cytokines; Dermatologic Agents; Fenretinide; Gene Expression Regulation; Humans; Lectins, C-Type; Lymphocyte Activation; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tetrahydronaphthalenes; Th2 Cells; Tretinoin; Tumor Cells, Cultured	2008
Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung. Journal of lipid research, 2010, Volume: 51, Issue:2 Topics: Absorption; Acyltransferases; Alitretinoin; Animals; Animals, Newborn; Benzoates; Biological Transport; Cytochrome P-450 Enzyme System; Drug Synergism; Esters; Gene Expression Regulation; Homeostasis; Hydrogen-Ion Concentration; Lung; Membrane Proteins; Rats; Rats, Sprague-Dawley; Retinoic Acid 4-Hydroxylase; Retinoids; Tetrahydronaphthalenes; Time Factors; Tretinoin; Vitamin A	2010
Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARalpha. Experimental dermatology, 2010, Jul-01, Volume: 19, Issue:7 Topics: Benzoates; Gene Expression Regulation; Humans; In Vitro Techniques; Keratin-13; Keratin-2; Keratin-4; Keratinocytes; Keratins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; RNA, Messenger; Skin; Tetrahydronaphthalenes; Tretinoin	2010
All-trans retinoic acid enhances the transport of phase II metabolites of benzo[a]pyrene by inducing the Breast Cancer Resistance Protein expression in Caco-2 cells. Toxicology letters, 2010, Aug-16, Volume: 197, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Benzoates; Caco-2 Cells; Gene Expression Regulation; Humans; Molecular Sequence Data; Neoplasm Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Tretinoin	2010
Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells. Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:11 Topics: Benzoates; Cell Differentiation; Cell Line; Dendritic Cells; Fatty Acid-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Ligands; Liver X Receptors; Monocytes; Nicotinic Acids; Orphan Nuclear Receptors; Phenotype; PPAR delta; PPAR gamma; Receptors, Calcitriol; Receptors, Retinoic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Tretinoin; Up-Regulation	2010
Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms. Journal of molecular endocrinology, 2011, Volume: 46, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Endometrium; Female; Gene Expression Profiling; Gene Knockdown Techniques; Genome; Humans; Microarray Analysis; Molecular Sequence Data; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Small Interfering; Signal Transduction; Tetrahydronaphthalenes; Tretinoin	2011
Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis. Development (Cambridge, England), 2011, Volume: 138, Issue:15 Topics: Animals; Benzoates; Cell Differentiation; Cell Proliferation; Follicle Stimulating Hormone; Male; Meiosis; Mice; Mice, Inbred C57BL; Mutation; Neuregulins; Oncogene Proteins v-erbB; RNA, Messenger; Spermatogonia; Teratogens; Testis; Tetrahydronaphthalenes; Tissue Culture Techniques; Tretinoin	2011
Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages. Biochimica et biophysica acta, 2012, Volume: 1821, Issue:4 Topics: Animals; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Benzoates; Biological Transport; Blotting, Western; Cell Line; Chlorocebus aethiops; Cholesterol; COS Cells; Gene Expression Regulation; HEK293 Cells; Humans; Liver X Receptors; Macrophages; Models, Genetic; Orphan Nuclear Receptors; Promoter Regions, Genetic; Protein Binding; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrahydronaphthalenes; Tretinoin	2012
Reduced retinoid signaling in the skin after systemic retinoid-X receptor ligand treatment in mice with potential relevance for skin disorders. Dermatology (Basel, Switzerland), 2012, Volume: 225, Issue:4 Topics: Administration, Oral; Administration, Topical; Animals; Benzoates; Chromatography, High Pressure Liquid; Female; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Organic Chemicals; Real-Time Polymerase Chain Reaction; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; RNA, Messenger; Signal Transduction; Skin; Skin Diseases; Tandem Mass Spectrometry; Tetrahydronaphthalenes; Tretinoin; Vitamin A	2012
Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist. The European journal of neuroscience, 2013, Volume: 37, Issue:7 Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzoates; Cognition; Down-Regulation; Insulysin; Mice; Microglia; Neprilysin; Neurons; Retinoid X Receptor alpha; Signal Transduction; Tetrahydronaphthalenes; Tretinoin	2013
BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells. Experimental cell research, 2014, Oct-01, Volume: 327, Issue:2 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Benzamides; Benzoates; Blotting, Western; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Myeloid Cell Leukemia Sequence 1 Protein; para-Aminobenzoates; Real-Time Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured	2014
Effects of Retinoids on Augmentation of Club Cell Secretory Protein. American journal of respiratory and critical care medicine, 2017, 10-01, Volume: 196, Issue:7 Topics: Aged; Anthracenes; Antioxidants; Benzoates; Bronchi; Diterpenes; Epithelial Cells; Female; Humans; In Vitro Techniques; Male; Middle Aged; Naphthols; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinyl Esters; Skin Diseases; Smoking; Tetrahydronaphthalenes; Thiophenes; Tretinoin; Uteroglobin; Vitamin A	2017
RARα/RXR synergism potentiates retinoid responsiveness in cutaneous T-cell lymphoma cell lines. Experimental dermatology, 2017, Volume: 26, Issue:11 Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzoates; Bexarotene; Cell Adhesion; Cell Line; Cell Movement; Cell Proliferation; Gene Expression; Humans; Integrin beta Chains; Lymphoma, T-Cell, Cutaneous; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin	2017
Suppression by an RAR-γ Agonist of Collagen Degradation Mediated by Corneal Fibroblasts. Investigative ophthalmology & visual science, 2017, 04-01, Volume: 58, Issue:4 Topics: Animals; Benzoates; Biphenyl Compounds; Cell Proliferation; Cell Survival; Collagen; Cornea; Corneal Keratocytes; Dose-Response Relationship, Drug; Immunoblotting; Interleukin-1beta; Male; Pyrazoles; Rabbits; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Tetrahydronaphthalenes; Tretinoin	2017
Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8 Clinical immunology (Orlando, Fla.), 2017, Volume: 183 Topics: Aged; Aged, 80 and over; Antigen Presentation; Antigens, CD1d; Antineoplastic Agents; B-Lymphocytes; Benzoates; CD8-Positive T-Lymphocytes; Female; Galactosylceramides; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Natural Killer T-Cells; Retinoic Acid Receptor alpha; Tetrahydronaphthalenes; Tretinoin	2017