am 580 and tretinoin
am 580 has been researched along with tretinoin in 57 studies
Research
Studies (57)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.51) | 18.7374 |
| 1990's | 14 (24.56) | 18.2507 |
| 2000's | 26 (45.61) | 29.6817 |
| 2010's | 15 (26.32) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Himi, T; Kagechika, H; Kawachi, E; Shudo, K | 1 |
| Hashimoto, Y; Himi, T; Kagechika, H; Kawachi, E; Shudo, K | 1 |
| Chandraratna, RA; Duong, TT; Klein, ES; Pino, ME; Teng, M | 1 |
| Beard, RL; Chandraratna, RA; Duong, TT; Klein, ES; Standevan, AM; Teng, M | 1 |
| Brann, MR; Currier, E; Eeg, A; Gauthier, NK; Hacksell, U; Lund, BW; Olsson, R; Piu, F; Sherbukhin, V | 1 |
| Bradley, KA; Damoiseaux, R; Gillespie, EJ; Huang, J; Manchester, M; Rogers, J; Sanchez, AM; Saxe, JP; Thomas, D | 1 |
| Charton, J; Deprez, B; Deprez-Poulain, R; Hennuyer, N; Staels, B; Tailleux, A | 1 |
| Begtrup, M; Gauthier, NK; Hacksell, U; Knapp, AE; Lund, BW; Olsson, R; Piu, F | 1 |
| Adams, DR; Barlow, S; Borthwick, AD; Brown, JT; Clarke, E; Corcoran, JPT; Goncalves, MB; Jarvis, CI; Kalindjian, SB; Miller, I; Ravier, E; Shiers, JJ; Smith, V; Taddei, DMA | 1 |
| Bauer, F; Bluethmann, H; Hoffmann, AS; Landwehr, J; LeMotte, P; Look, J | 1 |
| Hashimoto, Y; Heersche, JN; Von Schroeder, HP | 1 |
| Brooks, SC; Kazmer, S; Levin, AA; Yen, A | 1 |
| Barbui, T; Caccia, S; Garattini, E; Gianní, M; Guiso, G; Li Calzi, M; Rambaldi, A; Terao, M | 1 |
| Adamo, S; Avvisati, G; Benedetti, L; Diverio, D; Gambacorti-Passerini, C; Grignani, F; Jetten, AM; Levin, AA; Lo Coco, F; Nervi, C; Pelicci, PG; Scicchitano, BM | 1 |
| Elmazar, MM; Nau, H; Reichert, U; Shroot, B | 1 |
| Rogers, MB | 1 |
| Dawson, MI; Klaus, M; López-Boado, YS; López-Otín, C | 1 |
| Commes, T; Defacque, H; Marti, J; Piquemal, D; Rochette-Egly, C; Sévilla, C | 1 |
| Cho, Y; Talmage, DA; Tighe, AP | 1 |
| Li, Y; MacLennan, AJ; Rogers, MB | 1 |
| Bernardon, JM; Fésüs, L; Karászi, E; Michel, S; Reichert, U; Szondy, Z; Tóth, R | 1 |
| Kaiser, A; Nicke, B; Riecken, EO; Rosewicz, S; Wiedenmann, B | 1 |
| Démarchez, M; Diaz, BV; Frelin, C; Ladoux, A; Lenoir, MC; Michel, S | 1 |
| Funakoshi, Y; Ichiki, T; Ito, K; Takeda, K; Takeshita, A | 1 |
| Garattini, E; Gianni, M; Mologni, L; Ponzanelli, I; Rambaldi, A; Reichert, U; Terao, M | 1 |
| Habert, R; Livera, G; Rouiller-Fabre, V; Valla, J | 1 |
| Adam-Stitah, S; Haxsen, V; Ritz, E; Wagner, J | 1 |
| Lampen, A; Meyer, S; Nau, H | 1 |
| Devaux, Y; Grosjean, S; Latger-Cannard, V; Longrois, D; Meistelman, C; Mertes, PM; Rochette-Egly, C; Seguin-Devaux, C; Zannad, F | 1 |
| Afonja, O; Das, S; Helmer, E; Huang, A; Juste, D; Raaka, BM; Samuels, HH; Zhao, X | 1 |
| Gabriel, JL; Hutcheson, JM; Poynton, HC; Soprano, DR; Soprano, KJ; Zhang, ZP | 1 |
| Balducci, D; Bani, MR; Barbui, T; Falanga, A; Marchetti, M; Vignoli, A | 1 |
| Blomhoff, HK; Engedal, N; Ertesvag, A | 1 |
| Elmazar, MM; Nau, H | 1 |
| Kanaya, S; Kunii, R; Nemoto, E; Shibuya, N; Shimauchi, H | 1 |
| Dailloux, M; Devaux, Y; Hanriot, D; Latger-Cannard, V; Longrois, D; Mertes, PM; Seguin-Devaux, C; Zannad, F | 1 |
| Inoue, Y; Kawahara, H; Shirahata, S; Sugimoto, Y | 1 |
| Chen, Q; Ross, AC | 1 |
| Chiba, H; Kojima, T; Nishikiori, N; Ohguro, H; Osanai, M; Sawada, N | 1 |
| Chambon, P; Li, H; MacLean, G; Metzger, D; Petkovich, M | 1 |
| Chen, Q; Pai, T; Ross, AC; Zhang, Y; Zolfaghari, R | 1 |
| Hayashi, S; Ito, K; Matsumoto, M; Nagase, S; Niikura, H; Suzuki, T; Takano, T; Tamura, M; Tanabe, K; Utsunomiya, H; Yaegashi, N; Yoshinaga, K | 1 |
| Collins, G; Dawson, HD; Key, M; Pyle, R; Taub, DD | 1 |
| Ross, AC; Wu, L | 1 |
| Sirsjö, A; Törmä, H; Vahlquist, A; Virtanen, M | 1 |
| Hessel, S; Lampen, A | 1 |
| Dezsö, B; Lindstedt, M; Nagy, G; Nagy, L; Pap, A; Póliska, S; Rühl, R; Santegoets, SJ; Szanto, A; Szatmari, I; Széles, L | 1 |
| Bulun, SE; Cheng, YH; Pavone, ME; Utsunomiya, H; Yin, P | 1 |
| Abé, S; Eto, K; Honmyou, A; Kiyonari, H; Nakao, K; Zhang, J | 1 |
| Ayaori, M; Hisada, T; Iizuka, M; Ikewaki, K; Kagechika, H; Komatsu, T; Nakanishi, T; Nakaya, K; Ogura, M; Sasaki, M; Takiguchi, S; Terao, Y; Uehara, Y; Uto-Kondo, H; Yakushiji, E; Yogo, M | 1 |
| Aydemir, G; Blomhoff, R; Carlsen, H; Garcia, J; Gericke, J; Mihály, J; Rühl, R; Weiss, K | 1 |
| Clarke, E; Corcoran, JP; Deacon, R; Goncalves, MB; Hobbs, C; Jack, J; Malmqvist, T | 1 |
| Cione, E; Fletcher, S; Kane, MA; Perri, M; Yap, JL; Yu, J | 1 |
| Alberts, DS; Chen, Y; Di, PYP; Einspahr, J; Guerra, S; Krutzsch, M; Lizarraga, RE; Martinez, FD; Vasquez, MM; Zhu, L | 1 |
| Bridges, LC; Chen, J; Crouch, MJ; DeMarco, SS; Maiorana-Boutilier, AL; Peaks, MS; Phillips, CM; Shaikh, SR; Shewchuk, BM; Wang, L | 1 |
| Kimura, K; Kobayashi, M; Nishida, T; Orita, T; Sonoda, KH; Zhou, H | 1 |
| Browne, PV; Doherty, DG; Ghnewa, YG; McElligott, AM; O'Reilly, VP; Vandenberghe, E | 1 |
Other Studies
57 other study(ies) available for am 580 and tretinoin
| Article | Year |
|---|---|
Retinobenzoic acids. 4. Conformation of aromatic amides with retinoidal activity. Importance of trans-amide structure for the activity.
Topics: Amides; Benzoates; Cell Differentiation; Cell Line; Humans; Leukemia, Promyelocytic, Acute; Magnetic Resonance Spectroscopy; Molecular Structure; Retinoids; Structure-Activity Relationship | 1989 |
Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity.
Topics: Amides; Binding Sites; Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Methylation; Molecular Structure; Retinoids; Structure-Activity Relationship | 1988 |
Identification of a retinoic acid receptor alpha subtype specific agonist.
Topics: Aminobenzoates; Animals; Benzoates; Cell Line; Dose-Response Relationship, Drug; Genes, Reporter; Molecular Structure; Protein Binding; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Transcriptional Activation; Transfection | 1996 |
Synthesis and biological activity of retinoic acid receptor-alpha specific amides.
Topics: Amides; Antineoplastic Agents; Breast Neoplasms; Female; Humans; Hydrogen Bonding; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; Structure-Activity Relationship | 2002 |
Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist.
Topics: Administration, Oral; Animals; Benzoates; Binding Sites; Biological Availability; Biphenyl Compounds; Cells, Cultured; Humans; Models, Molecular; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, Retinoic Acid; Solubility; Structure-Activity Relationship; Thiazoles; Transcription, Genetic | 2005 |
Amiodarone and bepridil inhibit anthrax toxin entry into host cells.
Topics: Amiodarone; Animals; Anthrax; Antigens, Bacterial; Bacterial Toxins; Bepridil; Cell Line; Cell Survival; Chloroquine; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Macrophages, Peritoneal; Male; Mice; Molecular Structure; Rats; Rats, Inbred F344; Time Factors | 2007 |
Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives.
Topics: Carboxylic Acids; Oxadiazoles; Receptors, Retinoic Acid; Retinoids | 2009 |
Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands.
Topics: Cell Line, Tumor; Drug Design; Humans; Ligands; Receptors, Retinoic Acid; Structure-Activity Relationship | 2009 |
Design and synthesis of a potent, highly selective, orally bioavailable, retinoic acid receptor alpha agonist.
Topics: Administration, Oral; Aminobenzoates; Animals; Benzoates; Cell Survival; Chlorocebus aethiops; COS Cells; Drug Design; Half-Life; Hep G2 Cells; Humans; Mice; Microsomes, Liver; Rats; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Structure-Activity Relationship; Tetrahydronaphthalenes | 2018 |
Marked resistance of RAR gamma-deficient mice to the toxic effects of retinoic acid.
Topics: Animals; Base Sequence; Benzoates; Drug Resistance; Mice; Mice, Mutant Strains; Molecular Probes; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Retinoids; Skin; Tetrahydronaphthalenes; Tretinoin | 1995 |
The effects of natural and synthetic retinoids on the differentiation of RCJ C5.18 chondrogenic cells.
Topics: Animals; Benzoates; Cartilage; Cell Differentiation; Cell Line; Chalcone; Chalcones; Dose-Response Relationship, Drug; Glycosaminoglycans; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; Retinoids; Teratogens; Tetrahydronaphthalenes; Transcription Factors; Tretinoin | 1994 |
Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor-selective retinoic acid analogs.
Topics: Benzoates; Cell Differentiation; Chromans; Cyclohexanes; Fatty Acids, Unsaturated; Flow Cytometry; HL-60 Cells; Humans; Ligands; Neoplasm Proteins; Pentanoic Acids; Phosphorylation; Protein Processing, Post-Translational; Receptors, Retinoic Acid; Retinoblastoma Protein; Retinoid X Receptors; Retinoids; Structure-Activity Relationship; Substrate Specificity; Tetrahydronaphthalenes; Transcription Factors; Tretinoin | 1996 |
AM580, a stable benzoic derivative of retinoic acid, has powerful and selective cyto-differentiating effects on acute promyelocytic leukemia cells.
Topics: Alkaline Phosphatase; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antineoplastic Agents; Benzoates; Cell Differentiation; Gene Expression; Gene Expression Regulation, Neoplastic; Granulocyte Colony-Stimulating Factor; Granulocytes; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Macrophage-1 Antigen; Neoplasm Proteins; Oncogene Proteins, Fusion; Receptors, Retinoic Acid; RNA, Messenger; Sialic Acid Binding Ig-like Lectin 3; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin | 1996 |
Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.
Topics: Apoptosis; Benzoates; CD18 Antigens; Cell Differentiation; Chromosomes, Human, Pair 15; Chromosomes, Human, Pair 17; Cytosol; Drug Resistance, Neoplasm; Enzyme Induction; Fenretinide; Gene Expression Regulation, Leukemic; Humans; Isoenzymes; Leukemia, Promyelocytic, Acute; Neoplasm Proteins; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Protein Multimerization; Receptors, Retinoic Acid; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transglutaminases; Translocation, Genetic; Tretinoin; Tumor Cells, Cultured | 1996 |
Pattern of retinoid-induced teratogenic effects: possible relationship with relative selectivity for nuclear retinoid receptors RAR alpha, RAR beta, and RAR gamma.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Administration, Oral; Animals; Benzoates; Bone and Bones; Central Nervous System; Digestive System Abnormalities; Female; Mice; Naphthalenes; Pregnancy; Pregnancy Outcome; Receptors, Retinoic Acid; Retinoids; Tetrahydronaphthalenes; Tretinoin; Urogenital Abnormalities | 1996 |
Receptor-selective retinoids implicate retinoic acid receptor alpha and gamma in the regulation of bmp-2 and bmp-4 in F9 embryonal carcinoma cells.
Topics: Animals; Benzoates; Blotting, Northern; Bone Morphogenetic Proteins; Bucladesine; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Growth Substances; Mice; Neoplastic Stem Cells; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Theophylline; Tretinoin | 1996 |
Retinoic acid-induced expression of apolipoprotein D and concomitant growth arrest in human breast cancer cells are mediated through a retinoic acid receptor RARalpha-dependent signaling pathway.
Topics: Antineoplastic Agents; Apolipoproteins; Apolipoproteins D; Benzoates; Breast Neoplasms; Cell Division; Chromans; Female; Humans; Morpholines; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Signal Transduction; Tetrahydronaphthalenes; Tretinoin | 1996 |
Potentiation of VD-induced monocytic leukemia cell differentiation by retinoids involves both RAR and RXR signaling pathways.
Topics: Alitretinoin; Animals; Benzoates; Bexarotene; Cell Differentiation; Chromans; COS Cells; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Lymphoma, Large B-Cell, Diffuse; Molecular Structure; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured; Vitamin D | 1997 |
Retinoic acid induced growth arrest of human breast carcinoma cells requires protein kinase C alpha expression and activity.
Topics: Benzoates; Blotting, Northern; Blotting, Western; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Neoplasms, Hormone-Dependent; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1997 |
A putative G-protein-coupled receptor, H218, is down-regulated during the retinoic acid-induced differentiation of F9 embryonal carcinoma cells.
Topics: Animals; Benzoates; Bucladesine; Carcinoma, Embryonal; Cell Differentiation; Chromans; Down-Regulation; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; Mice; Naphthalenes; Neoplasm Proteins; Phenotype; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 1998 |
Inhibition of activation-induced apoptosis of thymocytes by all-trans- and 9-cis-retinoic acid is mediated via retinoic acid receptor alpha.
Topics: Alitretinoin; Animals; Antibodies; Antigens, CD; Apoptosis; Benzoates; Cells, Cultured; DNA Fragmentation; Male; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Protein Binding; Receptors, Antigen, T-Cell; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Thymus Gland; Transcription Factors; Tretinoin | 1998 |
Retinoic acid receptor alpha mediates growth inhibition by retinoids in human colon carcinoma HT29 cells.
Topics: Antineoplastic Agents; Benzoates; Cell Differentiation; Cell Division; Gene Expression; HT29 Cells; Humans; Isotretinoin; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin | 1999 |
Regulation of vascular endothelial growth factor expression in human keratinocytes by retinoids.
Topics: Adaptor Protein Complex 1; Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Benzoates; Cells, Cultured; Endothelial Growth Factors; Humans; Keratinocytes; Lymphokines; Membrane Proteins; Mice; Mice, Nude; Naphthalenes; Protein Binding; Receptors, Retinoic Acid; Retinoids; RNA, Messenger; Skin; Skin Transplantation; Tetrahydronaphthalenes; Transcriptional Activation; Tretinoin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Downregulation of angiotensin II type 1 receptor by all-trans retinoic acid in vascular smooth muscle cells.
Topics: Animals; Antineoplastic Agents; Aorta, Thoracic; Benzoates; Binding, Competitive; Cells, Cultured; CREB-Binding Protein; Cycloheximide; Down-Regulation; Gene Expression Regulation; Lac Operon; Luciferases; Muscle, Smooth, Vascular; Nuclear Proteins; Promoter Regions, Genetic; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; RNA, Messenger; Tetrahydronaphthalenes; Trans-Activators; Transcription Factors; Tretinoin | 2000 |
Retinoid-dependent growth inhibition, differentiation and apoptosis in acute promyelocytic leukemia cells. Expression and activation of caspases.
Topics: Alitretinoin; Antineoplastic Agents; Apoptosis; Benzoates; Caspases; Cell Differentiation; Cell Division; Enzyme Activation; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Tumor Cells, Cultured | 2000 |
Effects of retinoids on the meiosis in the fetal rat ovary in culture.
Topics: Animals; Benzoates; Female; Meiosis; Oogenesis; Organ Culture Techniques; Ovary; Rats; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoids; Tetrahydronaphthalenes; Tretinoin | 2000 |
Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells.
Topics: Alitretinoin; Angiotensin II; Animals; Benzoates; Cell Division; Cells, Cultured; COS Cells; DNA; Dose-Response Relationship, Drug; Gene Expression; Gene Expression Regulation; Luciferases; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; RNA, Messenger; Tetrahydronaphthalenes; Transcription Factor AP-1; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tretinoin | 2001 |
Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells.
Topics: Benzoates; Caco-2 Cells; Cytochrome P-450 Enzyme System; Docosahexaenoic Acids; Gene Expression Regulation, Enzymologic; Humans; Phytanic Acid; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid 4-Hydroxylase; Retinoid X Receptors; Signal Transduction; Tetrahydronaphthalenes; Transcription Factors; Tretinoin; Up-Regulation | 2001 |
Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo.
Topics: Animals; Benzoates; Blood Cell Count; DNA-Binding Proteins; Enzyme Activation; Interferon Regulatory Factor-1; Interferon-gamma; Liver; Lung; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphoproteins; Rats; Rats, Inbred WKY; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Spleen; T-Lymphocyte Subsets; Tetrahydronaphthalenes; Transcription Factors; Tretinoin | 2002 |
RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition.
Topics: Animals; Benzoates; Breast Neoplasms; Cell Cycle; Cell Division; Estradiol; Estrogens; Expressed Sequence Tags; Female; Gene Expression Regulation, Neoplastic; Gene Targeting; Genes, Dominant; Growth Substances; High Mobility Group Proteins; Humans; Kidney; Male; Mammary Glands, Animal; Mice; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Organ Specificity; Receptors, Estrogen; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor alpha; Retinoids; SOX9 Transcription Factor; Testis; Tetrahydronaphthalenes; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2002 |
Arginine of retinoic acid receptor beta which coordinates with the carboxyl group of retinoic acid functions independent of the amino acid residues responsible for retinoic acid receptor subtype ligand specificity.
Topics: Alanine; Amino Acid Substitution; Amino Acids; Animals; Arginine; Benzoates; Carbon Dioxide; Ligands; Mice; Models, Molecular; Mutagenesis, Site-Directed; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoic Acid Receptor gamma; Retinoids; Sensitivity and Specificity; Structure-Activity Relationship; Tetrahydronaphthalenes; Tretinoin | 2003 |
All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties.
Topics: Benzoates; Capillaries; Cell Line; Cell Line, Transformed; Dose-Response Relationship, Drug; Down-Regulation; Endothelium, Vascular; Fibrinolysis; Hemostasis; Humans; Plasminogen Activator Inhibitor 1; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Simian virus 40; Skin; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin; Tissue Plasminogen Activator; Tretinoin; Tumor Necrosis Factor-alpha; Umbilical Veins; Up-Regulation | 2003 |
Survival of activated human T lymphocytes is promoted by retinoic acid via induction of IL-2.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Apoptosis; Benzoates; Cell Survival; Cells, Cultured; DNA Fragmentation; Flow Cytometry; Humans; Interleukin-2; Lectins, C-Type; Lymphocyte Activation; Propidium; Receptors, Retinoic Acid; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Tretinoin | 2004 |
Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands.
Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Benzoates; Bexarotene; Dose-Response Relationship, Drug; Drug Synergism; Female; Gestational Age; Ligands; Mice; Mice, Inbred Strains; Phytanic Acid; Phytol; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Teratogens; Tetrahydronaphthalenes; Tretinoin; Vitamin A | 2004 |
Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells.
Topics: Alitretinoin; Alkaline Phosphatase; Ascorbic Acid; Benzoates; Cell Differentiation; Cells, Cultured; Cementogenesis; Dexamethasone; Enzyme Inhibitors; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Glycerophosphates; Humans; Isotretinoin; Periodontal Ligament; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Tetrahydronaphthalenes; Time Factors; Transcription Factors; Tretinoin | 2005 |
Retinoic acid amplifies the host immune response to LPS through increased T lymphocytes number and LPS binding protein expression.
Topics: Acute-Phase Proteins; Animals; Antibodies, Bacterial; Benzoates; Carrier Proteins; Cell Proliferation; Flow Cytometry; Gene Expression Regulation; Immune System; Interferon-gamma; Interleukin-2; Lipopolysaccharides; Listeria monocytogenes; Liver; Lymphocyte Count; Male; Membrane Glycoproteins; Nitric Oxide Synthase Type II; Rats; Rats, Inbred WKY; Receptors, Retinoic Acid; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Tetrahydronaphthalenes; Tretinoin | 2005 |
Retinoic acid improves a hybridoma culture in a fructose-based medium by up-regulation of fructose incorporation via retinoid nuclear receptors.
Topics: Antibodies, Monoclonal; Antibody Formation; Benzoates; Cell Growth Processes; Cell Line; Culture Media; Fructose; Glucose Transporter Type 5; Humans; Hybridomas; Lactic Acid; Methoprene; Receptors, Retinoic Acid; Retinoid X Receptors; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tetrahydronaphthalenes; Tretinoin; Up-Regulation | 2006 |
Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells.
Topics: Animals; Antigen Presentation; Antigens, CD1; Antigens, CD1d; Antineoplastic Agents; Benzoates; Cell Proliferation; Dactinomycin; Galactosylceramides; Gene Expression Regulation; Glycolipids; HL-60 Cells; Humans; Killer Cells, Natural; Lymphocyte Activation; Macrophages, Peritoneal; Male; Mice; Rats; Rats, Sprague-Dawley; Receptors, Retinoic Acid; Response Elements; Retinoic Acid Receptor alpha; RNA, Messenger; Spleen; T-Lymphocytes; Tetrahydronaphthalenes; Transcription, Genetic; Tretinoin; U937 Cells | 2007 |
Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains.
Topics: Animals; Benzoates; Calcium; Calpain; Cataract; Diabetes Mellitus, Experimental; Hydrogen Peroxide; Lens, Crystalline; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin | 2007 |
Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice.
Topics: Animals; Apoptosis; Benzoates; Cytochrome P-450 Enzyme System; Drug Resistance; Embryo, Mammalian; Leydig Cells; Male; Meiosis; Mice; Mice, Knockout; Retinoic Acid 4-Hydroxylase; Retinoids; Sertoli Cells; Spermatozoa; Testis; Tetrahydronaphthalenes; Tretinoin | 2007 |
Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells.
Topics: Benzoates; Cell Line; Galactose; Gene Expression Regulation, Enzymologic; Humans; Isoenzymes; Myeloid Cells; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Tetrahydronaphthalenes; Time Factors; Tretinoin; Up-Regulation | 2007 |
Expression of retinoic acid receptors in human endometrial carcinoma.
Topics: Antineoplastic Agents; Benzoates; Carcinoma; Cell Proliferation; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Gene Expression; Humans; Receptors, Retinoic Acid; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 2008 |
The Retinoic Acid Receptor-alpha mediates human T-cell activation and Th2 cytokine and chemokine production.
Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Agents; Benzoates; Cell Differentiation; Chromans; Cytokines; Dermatologic Agents; Fenretinide; Gene Expression Regulation; Humans; Lectins, C-Type; Lymphocyte Activation; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Tetrahydronaphthalenes; Th2 Cells; Tretinoin; Tumor Cells, Cultured | 2008 |
Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung.
Topics: Absorption; Acyltransferases; Alitretinoin; Animals; Animals, Newborn; Benzoates; Biological Transport; Cytochrome P-450 Enzyme System; Drug Synergism; Esters; Gene Expression Regulation; Homeostasis; Hydrogen-Ion Concentration; Lung; Membrane Proteins; Rats; Rats, Sprague-Dawley; Retinoic Acid 4-Hydroxylase; Retinoids; Tetrahydronaphthalenes; Time Factors; Tretinoin; Vitamin A | 2010 |
Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARalpha.
Topics: Benzoates; Gene Expression Regulation; Humans; In Vitro Techniques; Keratin-13; Keratin-2; Keratin-4; Keratinocytes; Keratins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; RNA, Messenger; Skin; Tetrahydronaphthalenes; Tretinoin | 2010 |
All-trans retinoic acid enhances the transport of phase II metabolites of benzo[a]pyrene by inducing the Breast Cancer Resistance Protein expression in Caco-2 cells.
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Benzoates; Caco-2 Cells; Gene Expression Regulation; Humans; Molecular Sequence Data; Neoplasm Proteins; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoid X Receptors; Retinoids; Signal Transduction; Tetrahydronaphthalenes; Tretinoin | 2010 |
Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells.
Topics: Benzoates; Cell Differentiation; Cell Line; Dendritic Cells; Fatty Acid-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation; Humans; Ligands; Liver X Receptors; Monocytes; Nicotinic Acids; Orphan Nuclear Receptors; Phenotype; PPAR delta; PPAR gamma; Receptors, Calcitriol; Receptors, Retinoic Acid; Signal Transduction; Tetradecanoylphorbol Acetate; Tetrahydronaphthalenes; Tretinoin; Up-Regulation | 2010 |
Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms.
Topics: Antineoplastic Agents; Apoptosis; Benzoates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Endometrial Neoplasms; Endometrium; Female; Gene Expression Profiling; Gene Knockdown Techniques; Genome; Humans; Microarray Analysis; Molecular Sequence Data; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; RNA, Small Interfering; Signal Transduction; Tetrahydronaphthalenes; Tretinoin | 2011 |
Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis.
Topics: Animals; Benzoates; Cell Differentiation; Cell Proliferation; Follicle Stimulating Hormone; Male; Meiosis; Mice; Mice, Inbred C57BL; Mutation; Neuregulins; Oncogene Proteins v-erbB; RNA, Messenger; Spermatogonia; Teratogens; Testis; Tetrahydronaphthalenes; Tissue Culture Techniques; Tretinoin | 2011 |
Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages.
Topics: Animals; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Benzoates; Biological Transport; Blotting, Western; Cell Line; Chlorocebus aethiops; Cholesterol; COS Cells; Gene Expression Regulation; HEK293 Cells; Humans; Liver X Receptors; Macrophages; Models, Genetic; Orphan Nuclear Receptors; Promoter Regions, Genetic; Protein Binding; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; Retinoids; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tetrahydronaphthalenes; Tretinoin | 2012 |
Reduced retinoid signaling in the skin after systemic retinoid-X receptor ligand treatment in mice with potential relevance for skin disorders.
Topics: Administration, Oral; Administration, Topical; Animals; Benzoates; Chromatography, High Pressure Liquid; Female; Ligands; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Organic Chemicals; Real-Time Polymerase Chain Reaction; Receptors, Retinoic Acid; Response Elements; Retinoid X Receptors; RNA, Messenger; Signal Transduction; Skin; Skin Diseases; Tandem Mass Spectrometry; Tetrahydronaphthalenes; Tretinoin; Vitamin A | 2012 |
Amyloid β inhibits retinoic acid synthesis exacerbating Alzheimer disease pathology which can be attenuated by an retinoic acid receptor α agonist.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzoates; Cognition; Down-Regulation; Insulysin; Mice; Microglia; Neprilysin; Neurons; Retinoid X Receptor alpha; Signal Transduction; Tetrahydronaphthalenes; Tretinoin | 2013 |
BCL-xL/MCL-1 inhibition and RARγ antagonism work cooperatively in human HL60 leukemia cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-X Protein; Benzamides; Benzoates; Blotting, Western; Cell Proliferation; Humans; Leukemia, Promyelocytic, Acute; Myeloid Cell Leukemia Sequence 1 Protein; para-Aminobenzoates; Real-Time Polymerase Chain Reaction; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin; Tumor Cells, Cultured | 2014 |
Effects of Retinoids on Augmentation of Club Cell Secretory Protein.
Topics: Aged; Anthracenes; Antioxidants; Benzoates; Bronchi; Diterpenes; Epithelial Cells; Female; Humans; In Vitro Techniques; Male; Middle Aged; Naphthols; Pulmonary Disease, Chronic Obstructive; Randomized Controlled Trials as Topic; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Retinoic Acid Receptor gamma; Retinyl Esters; Skin Diseases; Smoking; Tetrahydronaphthalenes; Thiophenes; Tretinoin; Uteroglobin; Vitamin A | 2017 |
RARα/RXR synergism potentiates retinoid responsiveness in cutaneous T-cell lymphoma cell lines.
Topics: Anticarcinogenic Agents; Antineoplastic Agents; Apoptosis; Benzoates; Bexarotene; Cell Adhesion; Cell Line; Cell Movement; Cell Proliferation; Gene Expression; Humans; Integrin beta Chains; Lymphoma, T-Cell, Cutaneous; Retinoic Acid Receptor alpha; Retinoid X Receptors; RNA, Messenger; Tetrahydronaphthalenes; Tretinoin | 2017 |
Suppression by an RAR-γ Agonist of Collagen Degradation Mediated by Corneal Fibroblasts.
Topics: Animals; Benzoates; Biphenyl Compounds; Cell Proliferation; Cell Survival; Collagen; Cornea; Corneal Keratocytes; Dose-Response Relationship, Drug; Immunoblotting; Interleukin-1beta; Male; Pyrazoles; Rabbits; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma; Tetrahydronaphthalenes; Tretinoin | 2017 |
Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8
Topics: Aged; Aged, 80 and over; Antigen Presentation; Antigens, CD1d; Antineoplastic Agents; B-Lymphocytes; Benzoates; CD8-Positive T-Lymphocytes; Female; Galactosylceramides; Humans; In Vitro Techniques; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Natural Killer T-Cells; Retinoic Acid Receptor alpha; Tetrahydronaphthalenes; Tretinoin | 2017 |