am 251 and mk 8245

am 251 has been researched along with mk 8245 in 1 studies

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belair, L; Black, WC; Bleasby, K; Chan, CC; Desroches, C; Du, X; Gordon, R; Guay, J; Guiral, S; Hafey, MJ; Hamelin, E; Huang, Z; Kennedy, B; Lachance, N; Landry, F; Li, CS; Mancini, J; Normandin, D; Oballa, RM; Pocai, A; Powell, DA; Ramtohul, YK; Skorey, K; Sturkenboom, W; Styhler, A; Sørensen, D; Waddleton, DM; Wang, H; Wong, S; Xu, L; Zhang, L1

Other Studies

1 other study(ies) available for am 251 and mk 8245

ArticleYear
Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Acetates; Animals; Cell Line; Diffusion; Dogs; Female; Harderian Gland; Hep G2 Cells; Hepatocytes; Humans; Hypoglycemic Agents; Hypolipidemic Agents; In Vitro Techniques; Liver; Liver-Specific Organic Anion Transporter 1; Macaca mulatta; Male; Mice; Mice, Inbred C57BL; Microsomes; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Skin; Solute Carrier Organic Anion Transporter Family Member 1B3; Species Specificity; Stearoyl-CoA Desaturase; Structure-Activity Relationship; Tetrazoles; Tissue Distribution

2011
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