am 251 and anandamide
am 251 has been researched along with anandamide in 151 studies
Research
Studies (151)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.66) | 18.2507 |
| 2000's | 69 (45.70) | 29.6817 |
| 2010's | 79 (52.32) | 24.3611 |
| 2020's | 2 (1.32) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Drmota, T; Elebring, T; Greasley, PJ; Hermansson, NO; Hjorth, S; Larsson, N; Leonova, J; Nilsson, K; Ryberg, E; Sjögren, S | 1 |
| Bradshaw, HB; Dunn, E; McHugh, D; Page, J | 1 |
| Andrenyak, DM; Deng, H; Dey, SK; Ma, W; Makriyannis, A; Moody, DE; Paria, BC; Schmid, HH; Schmid, PC | 1 |
| Gitlin, JM; Mitchell, JA; Stanford, SJ | 1 |
| Bottrill, FE; Ford, WR; Hiley, CR; Ho, WS; White, R | 1 |
| Kato, H; Kurihara, J; Nakane, S; Nishigaki, M; Okubo, Y; Sugiura, T; Suzuki, S; Takata, Y; Waku, K | 1 |
| Bennett, T; Gardiner, SM; Kemp, PA; March, JE | 1 |
| Breuer, A; Järvinen, K; Järvinen, T; Laine, K; Mechoulam, R | 1 |
| Fowler, CJ; Jacobsson, SO; Nilsson, O | 2 |
| Dougalis, A; Lees, G | 1 |
| Akerman, S; Goadsby, PJ; Kaube, H | 1 |
| Engler, C; Feuerstein, TJ; Steffens, M; Zentner, J | 1 |
| Caraballo, I; El Banoua, F; Fernandez-Espejo, E; Ferrer, B; Flores, JA; Galan-Rodriguez, B; Rodriguez de Fonseca, F | 1 |
| Hayashi, M; Ichihara, A; Kaneshiro, Y; Koura, Y; Okada, H; Saruta, T; Tada, Y; Temm, CJ | 1 |
| Mendiguren, A; Pineda, J | 2 |
| Alger, BE; Kim, J | 2 |
| Bátkai, S; Bukoski, RD; Harvey-White, J; Kunos, G; Liu, J; Mackie, K; Offertáler, L; Osei-Hyiaman, D; Pacher, P; Radaeva, S; Rudd, MA | 1 |
| Bianchi, R; Borsani, E; Buffoli, B; Rezzani, R; Ricci, F; Rodella, LF | 1 |
| Chen, P; Fang, X; Hu, S; Moore, SA; Spector, AA; Yao, J | 1 |
| Kendall, DA; O'Sullivan, SE; Randall, MD | 1 |
| Brotchie, JM; Brown, TM; Venderova, K | 1 |
| Gamber, KM; Macarthur, H; Westfall, TC | 1 |
| Baik, SK; Gaskari, SA; Lee, SS; Li, Y; Liu, H; Moezi, L | 1 |
| Egawa, S; Fukuyama, S; Maruyama, I; Matsuda, K; Matsuno, S; Mikami, Y; Sunamura, M; Takeda, K | 1 |
| Barun, S; Dileköz, E; Ercan, ZS; Sarioglu, Y; Vural, IM | 1 |
| Bazan, NG; Boudaba, C; Di, S; Harris, C; Marcheselli, VL; Popescu, IR; Tasker, JG; Weng, FJ | 1 |
| Bermúdez-Siva, FJ; Diaz-Molina, FJ; Fuentes, E; Juan-Pico, P; Nadal, A; Rodríguez de Fonseca, F; Sánchez Vera, I; Serrano, A | 1 |
| Beaulieu, P; De Léan, A; Guindon, J | 1 |
| Abesser, M; Ertl, G; Harvey-White, J; Wagner, JA | 1 |
| de la Cal, C; Elverdin, JC; Fernández-Solari, J; Iribarne, M; McCann, SM; Prestifilippo, JP; Rettori, V; Suburo, AM | 1 |
| Baik, SK; Dehpour, AR; Gaskari, SA; Lee, SS; Liu, H; Moezi, L | 1 |
| Cross-Mellor, SK; Ossenkopp, KP; Parker, LA; Piomelli, D | 1 |
| Aguiar, DC; Guimarães, FS; Moreira, FA | 1 |
| Ceranowicz, P; Cieszkowski, J; Dembiński, A; Dembiński, M; Hładki, W; Konturek, PC; Konturek, SJ; Pawlik, WW; Tomaszewska, R; Warzecha, Z | 1 |
| Ali, N; Chapman, V; Chimenti, M; de Lago, E; Fernandez-Ruiz, J; Kendall, DA; Millns, PJ; Ryland, E | 1 |
| Bennett, T; Gardiner, SM; Randall, MD; Wheal, AJ | 2 |
| Cameron-Smith, D; Cavuoto, P; Hatzinikolas, G; McAinch, AJ; Wittert, GA | 1 |
| Cristino, L; Davison, JS; Di Marzo, V; Guglielmotti, V; Oland, LD; Pittman, QJ; Sharkey, KA; Starowicz, K; Van Sickle, MD | 1 |
| Bianchi, R; Borsani, E; Labanca, M; Rodella, LF | 1 |
| Cisneros, M; Di Marzo, V; Matias, I; Navarro, L; Petrosino, S; Prospéro-García, O; Rueda-Orozco, PE; Soria-Gómez, E | 1 |
| Ali, AB | 1 |
| Gorzalka, BB; Hill, MN; Morrish, AC | 1 |
| Allescher, HD; Broedl, UC; Göke, B; Lutz, B; Marsicano, G; Sibaev, A; Storr, M; Yuece, B | 1 |
| Galicia, O; Martínez-Vargas, M; Montes-Rodriguez, CJ; Navarro, L; Prospero-García, O; Rueda-Orozco, PE; Soria-Gomez, E | 1 |
| Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lin, HC; Wang, YW; Yang, YY | 1 |
| Greenwood, R; Jayamanne, A; Mitchell, VA; Vaughan, CW | 1 |
| Balaban, PM; Bezuglov, VV; Bobrov, MY; Bravarenko, NI; Ierusalimsky, VN; Lemak, MS; Malyshev, AY; Storozhuk, MV | 1 |
| Adermark, L; Lovinger, DM | 1 |
| Carnevali, O; Migliarini, B | 1 |
| De Oliveira Alvares, L; Diehl, F; Genro, BP; Quillfeldt, JA | 1 |
| Araújo, JR; Azevedo, I; Gonçalves, P; Martel, F | 1 |
| Aguiar, DC; Corrêa, FM; Guimarães, FS; Lisboa, SF; Resstel, LB | 1 |
| Méndez-Díaz, M; Montes-Rodriguez, CJ; Prospéro-García, O; Rueda-Orozco, PE; Soria-Gomez, E | 1 |
| de Oliveira Alvares, L; Diehl, F; Molina, VA; Pasqualini Genro, B; Quillfeldt, JA | 1 |
| Almeida, NA; Costa-E-Sousa, RH; da Veiga, MA; Fonseca Bloise, F; Oliveira, KJ; Pazos-Moura, CC; Souza, LL | 1 |
| Billi, S; Farina, M; Franchi, AM; Gervasi, MG; Perez Martinez, S; Rapanelli, M; Ribeiro, ML | 1 |
| Han, ZH; He, B; Hu, LH; Jiang, LS; Pu, J | 1 |
| Adermark, L; Lovinger, DM; Talani, G | 1 |
| Gardiner, SM; Ho, WS | 1 |
| Araújo, JR; Gonçalves, P; Martel, F | 1 |
| Cendejas-Trejo, NM; Cruz-Martínez, AM; Escartín-Pérez, RE; Florán-Garduño, B; González-Hernández, B; Mancilla-Díaz, JM | 1 |
| Campantico, E; Cottone, E; Di Marzo, V; Franzoni, M; Guastalla, A; Pomatto, V | 1 |
| Chen, L; Li, F; Li, M; Li, YH; Pan, HL; Qiu, Y; Shi, J; Wang, L; Zhang, J | 1 |
| Correia-da-Silva, G; Fonseca, BM; Teixeira, NA | 1 |
| Jain, NS; Manna, SS; Umathe, SN; Utturwar, KS | 1 |
| Grider, JR; Kuemmerle, JF; Li, Y; Mahavadi, S; Martin, BR; Murthy, KS; Qiao, LY | 1 |
| Fraga, D; Parada, CA; Rae, GA; Souza, GE; Zanoni, CI | 1 |
| Floresco, SB; Gorzalka, BB; Hill, MN; Hillard, CJ; McLaughlin, RJ; Morrish, AC; Viau, V | 1 |
| Carnevali, O; Di Marzo, V; Migliarini, B; Petrosino, S; Piccinetti, CC | 1 |
| Horne, EA; Kreitzer, AC; Lerner, TN; Stella, N | 1 |
| Biwasa, KK; Hashiguchi, T; Kadomatsu, H; Kawahara, K; Kozono, S; Maruyama, I; Matsuyama, T; Nakajima, Y; Noguchi, K; Tancharoen, S; Yonamine, Y; Yoshimoto, T | 1 |
| Ali, AB; Todorova, M | 1 |
| Bingham, B; Gorzalka, BB; Gray, JM; Hill, MN; Hillard, CJ; Lee, TT; McLaughlin, RJ; Shrestha, L; Viau, V | 1 |
| Elverdin, JC; Fernandez-Solari, J; Ossola, CA; Prestifilippo, JP; Rettori, V | 1 |
| Corrêa, FM; da Silva, AL; Guimarães, FS; Lisboa, SF; Reis, DG; Resstel, LB | 1 |
| Alter, BJ; Burston, JJ; Cravatt, BF; Fowler, CJ; Gereau, RW; McKinney, MK; Pertwee, RG; Ross, RA; Thors, L; Wiley, JL | 1 |
| Alexander, SP; Randall, MD; Wheal, AJ | 1 |
| Barrett, DA; Colado, MI; Feng, S; Gutierrez-Lopez, MD; Llopis, N; O'Shea, E | 1 |
| Casarotto, PC; Gomes, FV; Guimarães, FS; Resstel, LB | 1 |
| Méndez-Díaz, M; Prospéro-García, O; Rueda-Orozco, PE; Ruiz-Contreras, AE | 1 |
| Grinfeld, E; Hryciw, DH; Jenkin, KA; McAinch, AJ | 1 |
| Barbosa, FF; Cabral, A; Izídio, GS; Leão, AH; Munguba, H; Ribeiro, AM; Silva, RH | 1 |
| Jain, NS; Manna, SS; Umathe, SN | 1 |
| Bhatia, C; Frazier, CJ; Hofmann, ME | 1 |
| Hayase, T | 1 |
| Altinsoy, A; Bagriacik, EU; Dileköz, E; Ercan, ZS; Ilhan, SÖ; Kul, O; Or, M; Sarioglu, Y; Seven, I; Tunccan, OG | 1 |
| Campbell, WB; Gomez-Granados, AD; Nithipatikom, K; Pfeiffer, AW; Tang, AT; Williams, CL | 1 |
| Li, DP; Li, Q; Ma, HJ; Shi, M; Song, SL; Zhang, Y | 1 |
| Ikegaya, Y; Matsuki, N; Norimoto, H; Pu, XP; Sun, Y | 1 |
| Bambico, FR; Gobbi, G; Gorzalka, BB; Hill, MN; Hillard, CJ; McLaughlin, RJ; Stuhr, KL | 1 |
| Guimarães, FS; Lisboa, SF | 1 |
| Chapman, CD; Currie, PJ; Dono, LM; French, MC; Schuette, LM; Weinberg, ZY | 1 |
| Bánki, B; Kenessey, I; Ladányi, A; Márk, A; Rásó, E; Tímár, J; Tóvári, J; Varga, N | 1 |
| Baranowska-Kuczko, M; Kozłowska, H; MacLean, MR; Malinowska, B | 1 |
| Heinbockel, T; Sun, L; Wang, ZJ | 1 |
| De Laurentiis, A; Elverdin, JC; Rettori, E; Rettori, V; Zorrilla Zubilete, M | 1 |
| Bermúdez-Silva, FJ; Blanco, E; Cifuentes, M; Crespillo, A; de Fonseca, FR; de la Torre, R; Grondona, JM; Luque-Rojas, MJ; Pastor, A; Pavón, FJ; Rivera, P; Serrano, A; Suárez, J; Vida, M | 1 |
| Ali, AB; De-May, CL | 1 |
| Duarte, ID; Pacheco, Dda F; Romero, TR | 1 |
| Lograno, MD; Romano, MR | 1 |
| Giuffrida, A; Martinez, AA; Seillier, A | 1 |
| Aguilar-Roblero, R; Arteaga Santacruz, V; Caynas-Rojas, S; Méndez-Díaz, M; Prospéro-García, O; Ruiz-Contreras, AE | 1 |
| Li, Q; Wang, SY; Wei, Y; Yang, J; Zhang, J; Zhang, Y; Zhou, JJ | 1 |
| Di Marzo, V; Piscitelli, F; Shinjyo, N; Verde, R | 1 |
| Cui, N; Du, Y; Li, Q; Ma, H; Zhang, Y | 1 |
| Antunes-Rodrigues, J; Elias, LL; Ruginsk, SG; Uchoa, ET | 1 |
| Aguiar, JC; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB | 1 |
| Farah, H; Gackiere, F; Khlaifia, A; Tell, F | 1 |
| Beaulieu, P; Bouchard, JF; Charron, S; Desroches, J | 1 |
| Camargo, LH; Guimarães, FS; Lisboa, SF; Magesto, AC; Resstel, LB | 1 |
| Al Kury, LT; Ali, RM; Galadari, S; Howarth, FC; Oz, M; Shuba, YM; Voitychuk, OI; Yang, KH | 1 |
| Cudeiro, J; Dasilva, M; Grieve, KL; Rivadulla, C | 1 |
| Canseco-Alba, A; Rodríguez-Manzo, G | 2 |
| Chen, MY; Shi, YG; Sun, LJ; Wan, L; Yu, JW; Zhang, XY | 1 |
| Chen, J; Chen, SL; Chen, X; Fang, JY; Feng, CC; Liu, Q; Wang, EM; Yan, XJ; Zhang, LY | 1 |
| Fišar, Z; Hroudová, J; Singh, N | 1 |
| Aguiar, DC; Hott, SC; Moreira, FA; Resstel, LB; Viana, TG | 1 |
| Liu, J; Pope, C | 1 |
| Aliczki, M; Balogh, Z; Haller, J; Varga, ZK | 1 |
| Bastos, JR; Batista, LA; Moreira, FA | 1 |
| D'Mello, C; Gaskari, SA; Kunos, G; Lee, SS; Liu, H | 1 |
| Binkowski, M; Czaja, M; Di Marzo, V; Kolosowska, N; Makuch, W; Malek, N; Morera, E; Mrugala, M; Przewlocka, B; Starowicz, K | 1 |
| Krych, L; Moulton, K; Qin, M; Smith, CB; Xia, Z; Zeidler, Z | 1 |
| Baranowska-Kuczko, M; Grzeda, E; Harasim, E; Luczaj, W; Malinowska, B; Schlicker, E | 1 |
| Nistri, A; Veeraraghavan, P | 1 |
| Fraga, D; Parada, CA; Rae, GA; Souza, GEP; Zampronio, AR; Zanoni, CIS | 1 |
| Kregiel, J; Malek, N; Popik, P; Rygula, R; Starowicz, K | 1 |
| Cox, CD; Gall, CM; Geschwind, DH; Karsten, CA; Lee, D; Peñagarikano, O; Piomelli, D; Wei, D | 1 |
| Gao, F; Ji, M; Li, F; Li, Q; Miao, Y; Qian, WJ; Sun, XH; Wang, SY; Wang, Z; Yang, W | 1 |
| Egan, JM; González-Mariscal, I; Kim, W; Krzysik-Walker, SM; Rouse, M | 1 |
| Guimarães, FS; Joca, SR; Sartim, AG | 1 |
| Coimbra, NC; Dos Anjos-Garcia, T; Falconi-Sobrinho, LL; Ullah, F | 1 |
| Chancellor, MB; Hikita, K; Honda, M; Kawamoto, B; Muraoka, K; Saito, M; Shimizu, S; Takenaka, A; Yoshimura, N | 1 |
| Dekanic, A; Nistri, A; Veeraraghavan, P | 1 |
| Baggio, CH; Bertoglio, LJ; Cristina de Carvalho, M; Cunha, JM; da Silva, LM; da Silva-Santos, JE; de Morais, H; de Souza, CP; Ferreira, DM; Vanvossen, AC; Zanoveli, JM | 1 |
| Matsuda, H; Taketo, M | 1 |
| Ferreirós, N; Geisslinger, G; King-Himmelreich, TS; Möser, CV; Niederberger, E; Russe, OQ; Schmetzer, J; Schreiber, Y; Wolters, MC | 1 |
| Cheng, J; Jiang, C; Wu, J; Yu, J; Zhou, X; Zong, Y | 1 |
| Akirav, I; Fidelman, S; Hillard, CJ; Lange, R; Mizrachi Zer-Aviv, T | 1 |
| Babinska, Z; Bari, M; D'Addario, C; Di Bartolomeo, M; Di Marco, R; Di Marzo, V; Drago, F; Drazanova, E; Giurdanella, G; Iannotti, FA; Maccarrone, M; Mechoulam, R; Micale, V; Pekarik, V; Piscitelli, F; Ruda-Kucerova, J; Salomone, S; Starcuk, Z; Stark, T; Sulcova, A; Wotjak, CT | 1 |
| Aguilera-Portillo, G; Colonnello, A; Galván-Arzate, S; Kotlar, I; Pedraza-Chaverri, J; Rangel-López, E; Santamaría, A; Serratos, IN; Túnez, I; Wajner, M | 1 |
| Coimbra, NC; Dos Anjos-Garcia, T | 1 |
| Correa, FM; Fassini, A; Guimarães, FS; Hartmann, A; Lisboa, SF; Resstel, LB; Scopinho, A | 1 |
| Luchtenburg, FJ; Richardson, MK; Schaaf, MJM | 1 |
| Liu, S; Liu, X; Lu, Y; Wu, Y; Xie, Y; Yang, R; Zhou, D; Zhou, Y | 1 |
| Almada, RC; Coimbra, NC; da Silva, JA; Dos Anjos-Garcia, T; Pigatto, GR; Wotjak, CT | 1 |
Other Studies
151 other study(ies) available for am 251 and anandamide
| Article | Year |
|---|---|
The orphan receptor GPR55 is a novel cannabinoid receptor.
Topics: Amino Acid Sequence; Animals; Arachidonic Acids; Binding Sites; Binding, Competitive; Cannabidiol; Cannabinoids; Cell Line; Cloning, Molecular; Cyclohexanols; Down-Regulation; Endocannabinoids; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Mice; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Polyunsaturated Alkamides; Rats; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Structure-Activity Relationship | 2007 |
Δ(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells.
Topics: Arachidonic Acids; Cell Line, Tumor; Cell Movement; Dronabinol; Endometrium; Female; Glycine; HEK293 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Receptors, G-Protein-Coupled; RNA, Messenger; Transfection | 2012 |
Effects of cannabinoids on preimplantation mouse embryo development and implantation are mediated by brain-type cannabinoid receptors.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoids; Cytochrome P-450 Enzyme Inhibitors; Dronabinol; Embryo Implantation; Embryo, Mammalian; Embryonic and Fetal Development; Embryonic Development; Endocannabinoids; Enzyme Inhibitors; Female; Glycerides; Male; Mice; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1998 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
Mechanisms of anandamide-induced vasorelaxation in rat isolated coronary arteries.
Topics: Amides; Animals; Arachidonic Acids; Capsaicin; Coronary Vessels; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Ethanolamines; Gap Junctions; Glycyrrhetinic Acid; In Vitro Techniques; Indoles; Indomethacin; Male; Palmitic Acids; Peptides; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Serotonin; Tetraethylammonium; Vasodilation | 2001 |
2-Arachidonoylglycerol and anandamide oppositely modulate norepinephrine release from the rat heart sympathetic nerves.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Dronabinol; Endocannabinoids; Glycerides; Male; Myocardium; Neurotransmitter Agents; Norepinephrine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Drug; Sympathetic Nervous System | 2001 |
Complex regional haemodynamic effects of anandamide in conscious rats.
Topics: Adrenergic beta-Agonists; Animals; Arachidonic Acids; Atropine; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Consciousness; Dose-Response Relationship, Drug; Endocannabinoids; Hemodynamics; Hindlimb; Male; Oxazines; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyrazoles; Rats; Rats, Sprague-Dawley; Renal Circulation; Serotonin; Serotonin Antagonists; Sodium Chloride; Splanchnic Circulation; Wakefulness | 2002 |
Comparison of the enzymatic stability and intraocular pressure effects of 2-arachidonylglycerol and noladin ether, a novel putative endocannabinoid.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cattle; Ciliary Body; Cornea; Endocannabinoids; Enzyme Stability; Female; Glycerides; Intraocular Pressure; Iris; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Cannabinoid; Receptors, Drug | 2002 |
Cannabinoid CB1 receptor activation does not prevent the toxicity of glutamate towards embryonic chick telencephalon primary cultures.
Topics: Animals; Arachidonic Acids; Cannabinoids; Cells, Cultured; Chick Embryo; Colforsin; Cyclic AMP; Cyclohexanols; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Endocannabinoids; Excitatory Amino Acid Antagonists; Glutamic Acid; L-Lactate Dehydrogenase; Models, Animal; Neurons; Pipecolic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Telencephalon | 2003 |
Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro.
Topics: Amidohydrolases; Analysis of Variance; Animals; Animals, Newborn; Arachidonic Acids; Benzoxazines; Cannabinoids; Capsaicin; Drug Interactions; Electric Stimulation; Electrophysiology; Endocannabinoids; Excitatory Postsynaptic Potentials; Hippocampus; Hypnotics and Sedatives; In Vitro Techniques; Long-Term Potentiation; Male; Morpholines; Naphthalenes; Neurons; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rimonabant; Sleep | 2004 |
Anandamide is able to inhibit trigeminal neurons using an in vivo model of trigeminovascular-mediated nociception.
Topics: Animals; Arachidonic Acids; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Endocannabinoids; Hypotension; Male; Neurons; Nitroprusside; Pain; Peptide Fragments; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Trigeminal Caudal Nucleus; Vasodilation | 2004 |
Cannabinoid CB1 receptor-mediated modulation of evoked dopamine release and of adenylyl cyclase activity in the human neocortex.
Topics: Adenylyl Cyclases; Amygdala; Animals; Arachidonic Acids; Benzoxazines; Binding Sites; Colforsin; Cyclic AMP; Cyclohexanols; Dopamine; Dronabinol; Electric Stimulation; Endocannabinoids; Female; Humans; Ligands; Male; Morpholines; Naphthalenes; Neocortex; Piperidines; Polyunsaturated Alkamides; Potassium; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Synaptosomes; Tetrodotoxin; Tritium | 2004 |
Experimental parkinsonism alters anandamide precursor synthesis, and functional deficits are improved by AM404: a modulator of endocannabinoid function.
Topics: Acyltransferases; Amidohydrolases; Amphetamine; Analysis of Variance; Animals; Antiparkinson Agents; Arachidonic Acids; Behavior, Animal; Brain Chemistry; Cell Count; Central Nervous System Stimulants; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Endocannabinoids; Functional Laterality; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Rotation; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Nigra; Tyrosine 3-Monooxygenase | 2004 |
Anandamide decreases glomerular filtration rate through predominant vasodilation of efferent arterioles in rat kidneys.
Topics: Animals; Arachidonic Acids; Arterioles; Blood Pressure; Cannabinoid Receptor Modulators; Dose-Response Relationship, Drug; Endocannabinoids; Glomerular Filtration Rate; Immunohistochemistry; Kidney; Kidney Glomerulus; Male; Microscopy, Fluorescence; Nephrons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2004 |
Cannabinoids enhance N-methyl-D-aspartate-induced excitation of locus coeruleus neurons by CB1 receptors in rat brain slices.
Topics: Action Potentials; Analgesics; Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Cyclohexanols; Drug Interactions; Electrophysiology; Endocannabinoids; Excitatory Amino Acid Agonists; In Vitro Techniques; Locus Coeruleus; Male; Morpholines; N-Methylaspartate; Naphthalenes; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant | 2004 |
Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Synergism; Endocannabinoids; Enzyme Inhibitors; Glycerides; Hippocampus; In Vitro Techniques; Isoenzymes; Male; Meloxicam; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Prostaglandin-Endoperoxide Synthases; Pyramidal Cells; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazines; Thiazoles | 2004 |
Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension.
Topics: Amidohydrolases; Angiotensin II; Animals; Arachidonic Acids; Benzamides; Benzyl Compounds; Blood Pressure; Camphanes; Carbamates; Dronabinol; Endocannabinoids; Endothelium, Vascular; Hypertension; Male; Models, Cardiovascular; Myocardial Contraction; Myocardium; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred Dahl; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Up-Regulation; Vascular Resistance; Vasodilation; Ventricular Function, Left | 2004 |
AM404, an inhibitor of anandamide reuptake decreases Fos-immunoreactivity in the spinal cord of neuropathic rats after non-noxious stimulation.
Topics: Animals; Arachidonic Acids; Capsaicin; Constriction; Dose-Response Relationship, Drug; Endocannabinoids; Immunohistochemistry; Indoles; Male; Physical Stimulation; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord | 2005 |
Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Modulators; Cell Culture Techniques; Cells, Cultured; Cyclooxygenase 2; Endocannabinoids; Endothelium, Vascular; Enzyme Induction; Kinetics; Mice; Piperidines; Polyunsaturated Alkamides; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Telencephalon; Thymidine | 2005 |
The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.
Topics: Animals; Apamin; Arachidonic Acids; Azepines; Barium Compounds; Biological Factors; Calcium; Cannabinoid Receptor Modulators; Capsaicin; Charybdotoxin; Chlorides; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Drug Interactions; Endocannabinoids; Endothelium, Vascular; Female; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Rimonabant; Vasodilation; Verapamil | 2005 |
Differential effects of endocannabinoids on [(3)H]-GABA uptake in the rat globus pallidus.
Topics: Animals; Arachidonic Acids; Binding, Competitive; Cannabinoid Receptor Modulators; Endocannabinoids; gamma-Aminobutyric Acid; Globus Pallidus; Glycerides; In Vitro Techniques; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Tritium | 2005 |
Cannabinoids augment the release of neuropeptide Y in the rat hypothalamus.
Topics: Analgesics; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Hypothalamus; Male; Neuropeptide Y; Organ Culture Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley | 2005 |
Role of endocannabinoids in the pathogenesis of cirrhotic cardiomyopathy in bile duct-ligated rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Bile Ducts; Cardiomyopathies; Endocannabinoids; Gene Expression; Liver Cirrhosis, Experimental; Male; Myocardial Contraction; Papillary Muscles; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrodotoxin; Ventricular Function, Left | 2005 |
The cannabinoid 1 receptor antagonist, AM251, prolongs the survival of rats with severe acute pancreatitis.
Topics: Acute Disease; Animals; Arachidonic Acids; Blood Pressure; Disease Models, Animal; Endocannabinoids; Fluorescent Antibody Technique, Indirect; Immunohistochemistry; Male; Pancreatitis, Acute Necrotizing; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Random Allocation; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Survival Rate; Taurocholic Acid; Time Factors | 2005 |
Effects of cannabinoid receptor activation on rabbit bisected vas deferens strips.
Topics: Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Agonists; Dose-Response Relationship, Drug; Endocannabinoids; In Vitro Techniques; Indoles; Male; Morpholines; Muscle Contraction; Muscle, Smooth; Naloxone; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptors, Cannabinoid; Sympathetic Nervous System; Vas Deferens | 2005 |
Activity-dependent release and actions of endocannabinoids in the rat hypothalamic supraoptic nucleus.
Topics: Animals; Arachidonic Acids; Benzoxazines; Benzyl Compounds; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycerides; In Vitro Techniques; Male; Morpholines; Naphthalenes; Neurons; Piperidines; Polyunsaturated Alkamides; Presynaptic Terminals; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptors, Presynaptic; Supraoptic Nucleus; Synaptic Transmission | 2005 |
Activation of cannabinoid CB1 receptors induces glucose intolerance in rats.
Topics: Animals; Arachidonic Acids; Blood Glucose; Cannabinoid Receptor Modulators; Endocannabinoids; Glucose Intolerance; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2006 |
Local interactions between anandamide, an endocannabinoid, and ibuprofen, a nonsteroidal anti-inflammatory drug, in acute and inflammatory pain.
Topics: Acute Disease; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Area Under Curve; Cannabinoid Receptor Modulators; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Endocannabinoids; Ibuprofen; Indoles; Inflammation; Male; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Random Allocation; Rats | 2006 |
2-Arachidonylglycerol acting on CB1 cannabinoid receptors mediates delayed cardioprotection induced by nitric oxide in rat isolated hearts.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cannabinoid Receptor Modulators; Coronary Vessels; Endocannabinoids; Glycerides; Heart; Heart Rate; Indoles; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Regional Blood Flow | 2006 |
The cannabinoid agonist WIN 55,212-2 inhibits TNF-alpha-induced neutrophil transmigration across ECV304 cells.
Topics: Analysis of Variance; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Line; Cell Movement; Chemotaxis; Cyclohexanols; Dose-Response Relationship, Drug; Dronabinol; Endocannabinoids; Endothelial Cells; Flow Cytometry; Humans; Indoles; Interleukin-8; L-Lactate Dehydrogenase; Morpholines; Naphthalenes; Neutrophils; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Receptors, Interleukin-8A; Receptors, Interleukin-8B; Thapsigargin; Tumor Necrosis Factor-alpha | 2006 |
Inhibition of salivary secretion by activation of cannabinoid receptors.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Colforsin; Cyclic AMP; Endocannabinoids; Immunohistochemistry; Indoles; Male; Methacholine Chloride; Norepinephrine; Parasympathomimetics; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Saliva; Submandibular Gland; Sympathomimetics | 2006 |
Anandamide mediates hyperdynamic circulation in cirrhotic rats via CB(1) and VR(1) receptors.
Topics: Animals; Arachidonic Acids; Bile Ducts; Blood Flow Velocity; Blood Pressure; Blotting, Western; Capsaicin; Cardiac Output; Disease Models, Animal; Endocannabinoids; Hyperemia; Indoles; Liver Circulation; Liver Cirrhosis, Biliary; Male; Mesenteric Artery, Superior; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Splanchnic Circulation; Time Factors; TRPV Cation Channels; Vascular Resistance; Vasodilation; Vasodilator Agents | 2006 |
Effects of the FAAH inhibitor, URB597, and anandamide on lithium-induced taste reactivity responses: a measure of nausea in the rat.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Association Learning; Avoidance Learning; Benzamides; Carbamates; Conditioning, Classical; Dose-Response Relationship, Drug; Endocannabinoids; Injections, Intraperitoneal; Lithium Chloride; Male; Nausea; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Vomiting | 2007 |
Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray.
Topics: Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Male; Maze Learning; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2007 |
Cannabinoids in acute gastric damage and pancreatitis.
Topics: Acute Disease; Animals; Arachidonic Acids; Cannabinoids; Ceruletide; DNA; Endocannabinoids; Gastric Mucosa; Interleukin-1beta; Male; Pancreas; Pancreatitis; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Restraint, Physical; Stomach Ulcer; Stress, Physiological | 2006 |
Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Calcium; Capsaicin; Carbamates; Cells, Cultured; Dopamine; Drug Interactions; Endocannabinoids; Fura-2; Furans; Ganglia, Spinal; Male; Membrane Potentials; Membrane Transport Proteins; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; TRPV Cation Channels | 2006 |
Effects of chronic nitric oxide synthase inhibition on the cardiovascular responses to cannabinoids in vivo and in vitro.
Topics: Animals; Arachidonic Acids; Benzoxazines; Blood Pressure; Cannabinoids; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Heart Rate; Hypertension; Male; Mesenteric Arteries; Morpholines; Muscle, Skeletal; Naphthalenes; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Renal Circulation; Splanchnic Circulation; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents | 2007 |
Effects of cannabinoid receptors on skeletal muscle oxidative pathways.
Topics: Adult; AMP-Activated Protein Kinases; Arachidonic Acids; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Female; Gene Expression Regulation; Gene Expression Regulation, Enzymologic; Heat-Shock Proteins; Humans; Male; Multienzyme Complexes; Muscle Fibers, Skeletal; Muscle, Skeletal; Obesity; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Piperidines; Polyunsaturated Alkamides; Protein Kinases; Protein Serine-Threonine Kinases; Pyrazoles; Receptor, Cannabinoid, CB1; RNA, Messenger; Thinness; Transcription Factors | 2007 |
Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.
Topics: Acrylamides; Animals; Antiemetics; Arachidonic Acids; Area Postrema; Autonomic Pathways; Brain Stem; Bridged Bicyclo Compounds, Heterocyclic; Cannabinoids; Capsaicin; Dopamine; Emetics; Endocannabinoids; Ferrets; Male; Mice; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Solitary Nucleus; TRPV Cation Channels; Vagus Nerve; Vomiting | 2007 |
AM404 decreases Fos-immunoreactivity in the spinal cord in a model of inflammatory pain.
Topics: Animals; Arachidonic Acids; Capsaicin; Endocannabinoids; Immunohistochemistry; Indoles; Inflammation; Male; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Spinal Cord; TRPV Cation Channels | 2007 |
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Arcuate Nucleus of Hypothalamus; Benzyl Compounds; Cannabinoid Receptor Modulators; Eating; Endocannabinoids; Glycerides; Hypothalamus; Immunohistochemistry; Male; Nucleus Accumbens; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Serotonin; Time Factors | 2007 |
Presynaptic Inhibition of GABAA receptor-mediated unitary IPSPs by cannabinoid receptors at synapses between CCK-positive interneurons in rat hippocampus.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Cannabinoid Receptor Modulators; Cholecystokinin; Dose-Response Relationship, Radiation; Electric Stimulation; Endocannabinoids; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Male; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Presynaptic Terminals; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, GABA-A; Synapses | 2007 |
Endocannabinoid modulation of male rat sexual behavior.
Topics: Amidohydrolases; Animals; Appetitive Behavior; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Consummatory Behavior; Dose-Response Relationship, Drug; Ejaculation; Endocannabinoids; Enzyme Inhibitors; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Long-Evans; Receptor, Cannabinoid, CB1; Sexual Behavior, Animal | 2008 |
Cardiovascular effects of cannabinoids in conscious spontaneously hypertensive rats.
Topics: Animals; Arachidonic Acids; Benzoxazines; Blood Pressure; Cannabinoids; Cardiovascular System; Consciousness; Endocannabinoids; Heart Rate; Hindlimb; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Cannabinoid, CB1; Renal Circulation; Species Specificity; Splanchnic Circulation; Vascular Resistance; Vasodilation | 2007 |
Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Electric Stimulation; Endocannabinoids; Intestinal Mucosa; Intestines; Male; Membrane Potentials; Mice; Mice, Knockout; Muscle, Smooth; Myoelectric Complex, Migrating; Neuromuscular Junction; Organ Culture Techniques; Peristalsis; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reflex; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
A potential function of endocannabinoids in the selection of a navigation strategy by rats.
Topics: Animals; Arachidonic Acids; Blotting, Western; Cannabinoid Receptor Modulators; Circadian Rhythm; Darkness; Endocannabinoids; Hippocampus; Immunohistochemistry; Light; Male; Maze Learning; Microinjections; Neostriatum; Orientation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reverse Transcriptase Polymerase Chain Reaction; RNA | 2008 |
Role of Ca2+-dependent potassium channels in in vitro anandamide-mediated mesenteric vasorelaxation in rats with biliary cirrhosis.
Topics: Acetylcholine; Animals; Apamin; Arachidonic Acids; Cannabinoid Receptor Modulators; Charybdotoxin; Common Bile Duct; Dose-Response Relationship, Drug; Endocannabinoids; Glyburide; Ligation; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Mesenteric Artery, Superior; Nitroprusside; Peptides; Phenylephrine; Piperidines; Polyunsaturated Alkamides; Potassium; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Potassium Chloride; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Actions of the endocannabinoid transport inhibitor AM404 in neuropathic and inflammatory pain models.
Topics: Analgesics; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Carrier Proteins; Disease Models, Animal; Endocannabinoids; Freund's Adjuvant; Inflammation; Ligation; Male; Motor Activity; Pain; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Sciatic Nerve; Sciatic Neuropathy; Time Factors | 2007 |
Cannabinoid regulation in identified synapse of terrestrial snail.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Cyclohexanols; Dose-Response Relationship, Radiation; Electric Stimulation; Endocannabinoids; Excitatory Postsynaptic Potentials; Nervous System; Neurons; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Snails; Synapses; Tritium | 2007 |
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release step.
Topics: Animals; Arachidonic Acids; Benzoxazines; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Corpus Striatum; Endocannabinoids; Furans; gamma-Aminobutyric Acid; Glutamic Acid; Glycerides; Long-Term Synaptic Depression; Membrane Potentials; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Synapses; Synaptic Transmission | 2007 |
Anandamide modulates growth and lipid metabolism in the zebrafish Danio rerio.
Topics: Animals; Arachidonic Acids; Endocannabinoids; Gene Expression Regulation, Developmental; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Larva; Lipid Metabolism; Liver; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Sterol Regulatory Element Binding Proteins; Zebrafish | 2008 |
Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms.
Topics: Animals; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Modulators; Endocannabinoids; gamma-Aminobutyric Acid; Hippocampus; Male; Memory; Motor Activity; Neural Inhibition; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2008 |
Lack of a significant effect of cannabinoids upon the uptake of 2-deoxy-D-glucose by Caco-2 cells.
Topics: Arachidonic Acids; Caco-2 Cells; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Cyclohexanols; Deoxyglucose; Dronabinol; Endocannabinoids; Humans; Indoles; Intestinal Absorption; Piperidines; Polyunsaturated Alkamides; Pyrazoles | 2008 |
Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats.
Topics: Animals; Arachidonic Acids; Blood Pressure; Conditioning, Operant; Endocannabinoids; Fear; Heart Rate; Male; Microinjections; Neurotransmitter Uptake Inhibitors; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2008 |
Impairment of endocannabinoids activity in the dorsolateral striatum delays extinction of behavior in a procedural memory task in rats.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Modulators; Corpus Striatum; Drug Administration Schedule; Endocannabinoids; Extinction, Psychological; Male; Maze Learning; Piperidines; Polyunsaturated Alkamides; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Wistar; Statistics as Topic | 2008 |
Opposite action of hippocampal CB1 receptors in memory reconsolidation and extinction.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Conditioning, Operant; Endocannabinoids; Extinction, Psychological; Hippocampus; Male; Memory; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2008 |
Acute effects of endocannabinoid anandamide and CB1 receptor antagonist, AM251 in the regulation of thyrotropin secretion.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Endocannabinoids; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Piperidines; Pituitary Gland; Polyunsaturated Alkamides; Pyrazoles; Radioimmunoassay; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Thyrotropin; Thyroxine; Triiodothyronine | 2008 |
The endocannabinoid system in bull sperm and bovine oviductal epithelium: role of anandamide in sperm-oviduct interaction.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Blotting, Western; Camphanes; Carbamates; Cattle; Endocannabinoids; Epithelium; Fallopian Tubes; Female; Immunohistochemistry; Male; Microscopy, Fluorescence; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa | 2009 |
Role of activated endocannabinoid system in regulation of cellular cholesterol metabolism in macrophages.
Topics: Animals; Arachidonic Acids; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Benzoxazines; Cannabinoid Receptor Modulators; CD36 Antigens; Cell Survival; Cells, Cultured; Cholesterol; Dose-Response Relationship, Drug; Endocannabinoids; Glycerides; Lipoproteins, LDL; Macrophages, Peritoneal; Mice; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; PPAR gamma; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Signal Transduction | 2009 |
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activity.
Topics: Action Potentials; Animals; Arachidonic Acids; Calcium Channel Agonists; Calcium Channels, L-Type; Cannabinoid Receptor Modulators; Endocannabinoids; Female; gamma-Aminobutyric Acid; Glutamic Acid; Male; Neostriatum; Neuronal Plasticity; Neurons; Organ Culture Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Synapses; Synaptic Transmission | 2009 |
Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats.
Topics: Acute Disease; Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Benzoxazines; Blood Pressure; Cannabinoids; Carbamates; Consciousness; Endocannabinoids; Hindlimb; Hypertension; Infusions, Intravenous; Injections, Intravenous; Male; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Renal Circulation; Splanchnic Circulation; Vascular Resistance; Vasodilation | 2009 |
Effect of cannabinoids upon the uptake of folic acid by BeWo cells.
Topics: Arachidonic Acids; Carrier Proteins; Cell Culture Techniques; Cell Line, Tumor; Cyclohexanols; Dronabinol; Drug Administration Schedule; Endocannabinoids; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hydrogen-Ion Concentration; Indoles; Membrane Transport Proteins; Piperidines; Placenta; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cell Surface | 2009 |
Role of cannabinoid CB1 receptors on macronutrient selection and satiety in rats.
Topics: Analysis of Variance; Animals; Appetite Regulation; Arachidonic Acids; Cannabinoid Receptor Modulators; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Eating; Endocannabinoids; Food Preferences; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Satiation | 2009 |
Goldfish CB1 mRNA expression is affected by fasting and anandamide administration.
Topics: Actins; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Endocannabinoids; Fasting; Female; Gene Expression; Goldfish; Male; Piperidines; Polymerase Chain Reaction; Polyunsaturated Alkamides; Prosencephalon; Pyrazoles; Receptor, Cannabinoid, CB1; Rhombencephalon; RNA, Messenger; Time Factors | 2009 |
Endogenous anandamide and cannabinoid receptor-2 contribute to electroacupuncture analgesia in rats.
Topics: Animals; Arachidonic Acids; Chromatography, High Pressure Liquid; Electroacupuncture; Endocannabinoids; Freund's Adjuvant; Hindlimb; Hot Temperature; Hyperalgesia; Indoles; Male; Pain; Pain Management; Physical Stimulation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Skin | 2009 |
Anandamide-induced cell death: dual effects in primary rat decidual cell cultures.
Topics: Animals; Apoptosis; Arachidonic Acids; beta-Cyclodextrins; Cannabinoid Receptor Modulators; Cell Death; Cells, Cultured; Cholesterol; Decidua; Dose-Response Relationship, Drug; Endocannabinoids; Female; Membrane Lipids; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pyrazoles; Rats; Receptor, Cannabinoid, CB1 | 2009 |
Endocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptors.
Topics: Acetaminophen; Animals; Anti-Anxiety Agents; Anxiety; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Modulators; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Endocannabinoids; Injections, Intraventricular; Interpersonal Relations; Male; Mice; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1 | 2009 |
Modulation of motor and sensory pathways of the peristaltic reflex by cannabinoids.
Topics: Animals; Arachidonic Acids; Calcitonin Gene-Related Peptide; Cannabinoid Receptor Modulators; Colon; Dose-Response Relationship, Drug; Endocannabinoids; Guinea Pigs; In Vitro Techniques; Indoles; Motor Neurons; Neural Inhibition; Peristalsis; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reflex; Sensory Receptor Cells; Substance P; Vasoactive Intestinal Peptide | 2009 |
Endogenous cannabinoids induce fever through the activation of CB1 receptors.
Topics: Animals; Arachidonic Acids; Body Temperature; Body Temperature Regulation; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; Fever; Lipopolysaccharides; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2009 |
Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis.
Topics: Amidohydrolases; Amygdala; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Corticosterone; Dronabinol; Drug Interactions; Endocannabinoids; Hypothalamo-Hypophyseal System; Male; Microinjections; Piperidines; Pituitary-Adrenal System; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Restraint, Physical; Signal Transduction; Stress, Psychological | 2009 |
Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish.
Topics: Animals; Arachidonic Acids; Brain Chemistry; Cannabinoid Receptor Modulators; Eating; Endocannabinoids; Food Deprivation; Glycerides; Liver; Neuropeptide Y; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; RNA, Messenger; Sea Bream; Water | 2010 |
Effect of the CB(1) receptor antagonists rimonabant and AM251 on the firing rate of dorsal raphe nucleus neurons in rat brain slices.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cannabinoids; Endocannabinoids; gamma-Aminobutyric Acid; Male; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin | 2009 |
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.
Topics: Adenosine A2 Receptor Antagonists; Afferent Pathways; Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Central Nervous System Stimulants; Cerebral Cortex; Corpus Striatum; Endocannabinoids; Glutamic Acid; Glycerides; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Pyrimidines; Receptor, Cannabinoid, CB1; Signal Transduction | 2010 |
Involvement of the endocannabinoid system in periodontal healing.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Cell Proliferation; Endocannabinoids; Fibroblasts; Gingival Crevicular Fluid; Glycerides; Humans; Indoles; p38 Mitogen-Activated Protein Kinases; Periodontium; Phosphatidylinositol 3-Kinases; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Wound Healing | 2010 |
Asynchronous release of GABA via tonic cannabinoid receptor activation at identified interneuron synapses in rat CA1.
Topics: Animals; Animals, Newborn; Arachidonic Acids; CA1 Region, Hippocampal; Cannabinoid Receptor Modulators; Chelating Agents; Cholecystokinin; Dendrites; Egtazic Acid; Endocannabinoids; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Lysine; Male; Neural Inhibition; Neural Pathways; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synapses | 2010 |
Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapses.
Topics: Agatoxins; Animals; Arachidonic Acids; Benzamides; Benzoxazines; Biophysics; Calcium; Calcium Channel Blockers; Cannabinoid Receptor Modulators; Carbamates; Conotoxins; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycerides; Hippocampus; Homeostasis; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Morpholines; Naphthalenes; Nerve Net; Neural Inhibition; Neurons; Patch-Clamp Techniques; Piperidines; Polyamines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rimonabant; Sodium Channel Blockers; Synapses; Tetrodotoxin | 2010 |
Endogenous cannabinoid signaling is essential for stress adaptation.
Topics: Adaptation, Physiological; Analysis of Variance; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Corticosterone; Endocannabinoids; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Signal Transduction; Stress, Physiological | 2010 |
Participation of the endocannabinoid system in lipopolysaccharide-induced inhibition of salivary secretion.
Topics: Amidohydrolases; Animals; Arachidonic Acid; Arachidonic Acids; Cannabinoid Receptor Modulators; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Endocannabinoids; Etanercept; Immunoglobulin G; Immunologic Factors; In Vitro Techniques; Indoles; Lipopolysaccharides; Male; Methacholine Chloride; Muscarinic Agonists; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Saliva; Salivation; Secretory Rate; Submandibular Gland; Tumor Necrosis Factor-alpha | 2010 |
Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Blood Pressure; Cannabinoid Receptor Modulators; Carbolines; Conditioning, Classical; Electroshock; Endocannabinoids; Fear; Freezing Reaction, Cataleptic; GABA Antagonists; Heart Rate; Male; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synaptic Transmission | 2010 |
Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Behavior, Animal; Benzamides; Brain; Cannabinoid Receptor Antagonists; Carbamates; Cell Line, Transformed; Chlorocebus aethiops; COS Cells; Drug Interactions; Endocannabinoids; Extracellular Signal-Regulated MAP Kinases; Formaldehyde; Genistein; Humans; Isoflavones; Liver; Mice; Mice, Inbred ICR; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats | 2010 |
Vasorelaxation to N-oleoylethanolamine in rat isolated arteries: mechanisms of action and modulation via cyclooxygenase activity.
Topics: Animals; Aorta, Thoracic; Arachidonic Acids; Caffeine; Capsaicin; Chloride Channels; Endocannabinoids; Endothelium, Vascular; Ethanolamines; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Nitric Oxide; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Sensory Receptor Cells; Vasodilation | 2010 |
Involvement of 2-arachidonoyl glycerol in the increased consumption of and preference for ethanol of mice treated with neurotoxic doses of methamphetamine.
Topics: Alcohol Drinking; Amidohydrolases; Animals; Arachidonic Acids; Central Nervous System Stimulants; Choice Behavior; Dopamine; Dopamine Plasma Membrane Transport Proteins; Endocannabinoids; Glycerides; Limbic System; Male; Methamphetamine; Mice; Mice, Inbred C57BL; Monoacylglycerol Lipases; Neurotoxicity Syndromes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1 | 2010 |
Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Behavior, Animal; Benzamides; Benzoxazines; Calcium Channel Blockers; Cannabinoids; Carbamates; Drug Interactions; Endocannabinoids; Male; Mice; Mice, Inbred C57BL; Morpholines; Motor Activity; Naphthalenes; Obsessive-Compulsive Disorder; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Synaptic Transmission | 2011 |
The endocannabinoid system modulates the valence of the emotion associated to food ingestion.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Eating; Emotions; Endocannabinoids; Oleic Acids; Piperidines; Polyunsaturated Alkamides; Psychomotor Performance; Pyrazoles; Rats; Rats, Wistar | 2012 |
Role for cannabinoid receptors in human proximal tubular hypertrophy.
Topics: Animals; Arachidonic Acids; Cell Enlargement; Cell Line; Endocannabinoids; Humans; Indoles; Kidney Tubules, Proximal; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, G-Protein-Coupled; TRPV Cation Channels | 2010 |
Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats.
Topics: Amygdala; Analysis of Variance; Animals; Anxiety; Arachidonic Acids; Avoidance Learning; Cannabinoid Receptor Modulators; Discrimination Learning; Endocannabinoids; Male; Maze Learning; Memory; Microinjections; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2011 |
Involvement of endocannabinoids in antidepressant and anti-compulsive effect of fluoxetine in mice.
Topics: Animals; Antidepressive Agents; Arachidonic Acids; Benzamides; Cannabinoid Receptor Modulators; Carbamates; Compulsive Behavior; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Endocannabinoids; Fluoxetine; Injections, Intraventricular; Male; Mice; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles | 2011 |
Cannabinoid receptor agonists potentiate action potential-independent release of GABA in the dentate gyrus through a CB1 receptor-independent mechanism.
Topics: Action Potentials; Animals; Arachidonic Acids; Benzoxazines; Calcium; Cannabinoids; Endocannabinoids; Exocytosis; GABAergic Neurons; gamma-Aminobutyric Acid; Glycerides; Male; Morpholines; Mossy Fibers, Hippocampal; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Synaptic Transmission | 2011 |
Differential effects of TRPV1 receptor ligands against nicotine-induced depression-like behaviors.
Topics: Animals; Antidepressive Agents; Arachidonic Acids; Capsaicin; Depression; Dopamine; Endocannabinoids; Hindlimb Suspension; Ligands; Male; Mice; Mice, Inbred ICR; Nicotine; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Stress, Psychological; Swimming; TRPV Cation Channels | 2011 |
A cannabinoid ligand, anandamide, exacerbates endotoxin-induced uveitis in rabbits.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Disease Models, Animal; Drug Synergism; Endocannabinoids; Intravitreal Injections; Leukocyte Count; Lipopolysaccharides; Male; Neutrophil Infiltration; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rabbits; Receptor, Cannabinoid, CB1; Severity of Illness Index; Uveitis | 2011 |
Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells.
Topics: Actins; Arachidonic Acids; Benzoxazines; Biological Transport, Active; cdc42 GTP-Binding Protein; Cell Line, Tumor; Cell Membrane; Cell Movement; Endocannabinoids; Glycerides; Humans; Male; Morpholines; Myosins; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Prostatic Neoplasms; Pyrazoles; rac1 GTP-Binding Protein; Receptor, Cannabinoid, CB1; rhoA GTP-Binding Protein | 2012 |
Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels.
Topics: Animals; Anti-Arrhythmia Agents; Arachidonic Acids; Arrhythmias, Cardiac; Cardiac Electrophysiology; Dose-Response Relationship, Drug; Endocannabinoids; Heart Ventricles; Indoles; KATP Channels; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2012 |
Cannabinoid receptor activation disrupts the internal structure of hippocampal sharp wave-ripple complexes.
Topics: Animals; Arachidonic Acids; Calcium; Cannabinoid Receptor Modulators; Endocannabinoids; Hippocampus; Male; Memory; Mice; Mice, Inbred C57BL; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Sleep | 2012 |
Prefrontal cortical anandamide signaling coordinates coping responses to stress through a serotonergic pathway.
Topics: Action Potentials; Adaptation, Psychological; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Endocannabinoids; Enzyme Inhibitors; Fenclonine; Glycerides; Male; Microinjections; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pyrazoles; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Serotonergic Neurons; Signal Transduction; Stress, Psychological | 2012 |
Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Modulators; Endocannabinoids; Escape Reaction; Male; Nitric Oxide; Nitric Oxide Donors; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2012 |
Paraventricular nucleus anandamide signaling alters eating and substrate oxidation.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Eating; Endocannabinoids; Energy Metabolism; Male; Oxidation-Reduction; Paraventricular Hypothalamic Nucleus; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid | 2012 |
Revisiting CB1 receptor as drug target in human melanoma.
Topics: Animals; Apoptosis; Arachidonic Acids; Base Sequence; Cannabinoids; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Endocannabinoids; Humans; Ligands; Liver Neoplasms; Melanoma; Mice; Mice, SCID; Microscopy, Fluorescence; Molecular Sequence Data; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Xenograft Model Antitumor Assays | 2012 |
Endothelium-dependent mechanisms of the vasodilatory effect of the endocannabinoid, anandamide, in the rat pulmonary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amidohydrolases; Animals; Anisoles; Apamin; Arachidonic Acids; Benzamides; Benzyl Compounds; Cannabinoid Receptor Antagonists; Capsaicin; Carbamates; Charybdotoxin; Cyclohexanes; Endocannabinoids; Endothelium, Vascular; Imidazoles; Indoles; Indomethacin; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Pulmonary Artery; Pyrazoles; Rats; Rats, Wistar; Receptors, Cannabinoid; Receptors, Epoprostenol; Tetraethylammonium; TRPV Cation Channels; Vasodilation | 2012 |
Cannabinoid receptor-mediated regulation of neuronal activity and signaling in glomeruli of the main olfactory bulb.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cannabinoids; Data Interpretation, Statistical; Endocannabinoids; Excitatory Amino Acid Antagonists; Female; Male; Mice; Mice, Inbred C57BL; Morpholines; Naphthalenes; Nerve Net; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Signal Transduction; Synapses; Synaptic Transmission | 2012 |
Anti-inflammatory effect of the endocannabinoid anandamide in experimental periodontitis and stress in the rat.
Topics: Alveolar Bone Loss; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Body Weight; Cannabinoid Receptor Agonists; Corticosterone; Disease Models, Animal; Endocannabinoids; Enzyme-Linked Immunosorbent Assay; Exploratory Behavior; Indoles; Interleukin-1beta; Male; Nitric Oxide Synthase; Periodontitis; Piperidines; Polyunsaturated Alkamides; Prostaglandins E; Pyrazoles; Rats; Rats, Wistar; Statistics, Nonparametric; Stress, Psychological; Tumor Necrosis Factor-alpha | 2012 |
Diet-dependent modulation of hippocampal expression of endocannabinoid signaling-related proteins in cannabinoid antagonist-treated obese rats.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Diet, High-Fat; Dietary Carbohydrates; Dietary Fats; Endocannabinoids; Hippocampus; Lipoprotein Lipase; Male; Monoacylglycerol Lipases; Obesity; Phospholipase D; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Weight Gain | 2013 |
Cell type-specific regulation of inhibition via cannabinoid type 1 receptors in rat neocortex.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Endocannabinoids; Inhibitory Postsynaptic Potentials; Interneurons; Male; Neocortex; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Pyramidal Cells; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Synaptic Transmission | 2013 |
Probable involvement of Ca(2+)-activated Cl(-) channels (CaCCs) in the activation of CB1 cannabinoid receptors.
Topics: Amides; Analysis of Variance; Animals; Arachidonic Acids; Calcium Channel Blockers; Cannabinoid Receptor Agonists; Chloride Channels; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Ethanolamines; Hyperalgesia; Indoles; Male; Niflumic Acid; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2013 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Endocannabinoids; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Polyunsaturated Alkamides; Protein Kinase C; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Muscarinic M3; rho-Associated Kinases | 2013 |
Phencyclidine-induced social withdrawal results from deficient stimulation of cannabinoid CB₁ receptors: implications for schizophrenia.
Topics: Amidohydrolases; Amygdala; Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbamates; Cyclohexanols; Dose-Response Relationship, Drug; Endocannabinoids; Male; Phencyclidine; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pyrazoles; Quinazolinones; Rats; Receptor, Cannabinoid, CB1; Receptor, Cholecystokinin B; Rimonabant; Schizophrenia; Social Behavior | 2013 |
Entopeduncular nucleus endocannabinoid system modulates sleep-waking cycle and mood in rats.
Topics: Affect; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Endocannabinoids; Entopeduncular Nucleus; Immobility Response, Tonic; Male; Maze Learning; Microinjections; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Rotarod Performance Test; Sleep; Sleep Stages; Wakefulness | 2013 |
Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits.
Topics: Action Potentials; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Endocannabinoids; Indoles; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Polyunsaturated Alkamides; Potassium Channel Blockers; Pyrazoles; Rabbits; Sinoatrial Node | 2013 |
Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system.
Topics: Acetyltransferases; Analysis of Variance; Animals; Arachidonic Acids; Astrocytes; Cell Differentiation; Cells, Cultured; Endocannabinoids; gamma-Aminobutyric Acid; Glial Fibrillary Acidic Protein; Glycerides; Linoleic Acid; Mass Spectrometry; Mice; Neural Stem Cells; Piperidines; Polyunsaturated Alkamides; Pyrazoles; RNA, Messenger; Up-Regulation | 2013 |
Anandamide reduces intracellular Ca2+ concentration through suppression of Na+/Ca2+ exchanger current in rat cardiac myocytes.
Topics: Aniline Compounds; Animals; Arachidonic Acids; Calcium; Cannabinoids; Cell Separation; Endocannabinoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heart Ventricles; Indoles; Intracellular Space; Ion Channel Gating; Male; Myocardial Ischemia; Myocytes, Cardiac; Pertussis Toxin; Phenyl Ethers; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Sodium-Calcium Exchanger; Solutions | 2013 |
Anandamide modulates the neuroendocrine responses induced by extracellular volume expansion.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Benzamides; Carbamates; Endocannabinoids; Gene Expression Regulation; Infusions, Intraventricular; Male; Median Eminence; Neuroprotective Agents; Nitrates; Oxytocin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; RNA, Messenger; Saline Solution, Hypertonic; Vasopressins | 2013 |
Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats.
Topics: Animals; Anxiety; Apomorphine; Arachidonic Acids; Bicuculline; Cannabinoid Receptor Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; GABA-A Receptor Antagonists; Male; Maze Learning; Nitric Oxide Synthase; Oxadiazoles; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2013 |
Anandamide, cannabinoid type 1 receptor, and NMDA receptor activation mediate non-Hebbian presynaptically expressed long-term depression at the first central synapse for visceral afferent fibers.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; In Vitro Techniques; Long-Term Synaptic Depression; Male; Medulla Oblongata; Neurons; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Presynaptic Terminals; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, N-Methyl-D-Aspartate; Visceral Afferents | 2013 |
Endocannabinoids decrease neuropathic pain-related behavior in mice through the activation of one or both peripheral CB₁ and CB₂ receptors.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Endocannabinoids; Glycerides; Hyperalgesia; Male; Mice; Mice, Knockout; Neuralgia; Pain Measurement; Pain Threshold; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2 | 2014 |
Cannabinoid modulation of predator fear: involvement of the dorsolateral periaqueductal gray.
Topics: Animals; Arachidonic Acids; Benzoxazines; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cats; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Fear; Male; Microinjections; Morpholines; Naphthalenes; Nitric Oxide Synthase Type I; Ornithine; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Predatory Behavior; Pyrazoles; Rats; Receptor, Cannabinoid, CB1 | 2014 |
Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes.
Topics: Action Potentials; Animals; Arachidonic Acids; Caffeine; Calcium; Calcium Signaling; Endocannabinoids; Fura-2; Heart Ventricles; In Vitro Techniques; Indoles; Male; Myocardial Contraction; Myocytes, Cardiac; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Sarcoplasmic Reticulum; Transport Vesicles | 2014 |
Anandamide activation of CB1 receptors increases spontaneous bursting and oscillatory activity in the thalamus.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Electroencephalography; Endocannabinoids; Geniculate Bodies; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Visual Cortex | 2014 |
Low anandamide doses facilitate male rat sexual behaviour through the activation of CB1 receptors.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Copulation; Endocannabinoids; Male; Motor Activity; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Sexual Behavior, Animal | 2014 |
Endocannabinoid system activation contributes to glucose metabolism disorders of hepatocytes and promotes hepatitis C virus replication.
Topics: AMP-Activated Protein Kinases; Arachidonic Acids; Cell Line; Cell Survival; Coculture Techniques; Cyclic AMP Response Element-Binding Protein; Endocannabinoids; Genome, Viral; Glucose Metabolism Disorders; Glucose Transporter Type 2; Glucose-6-Phosphatase; Glycerides; Hepacivirus; Hepatic Stellate Cells; Hepatitis C, Chronic; Hepatocytes; Humans; Phosphorylation; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Real-Time Polymerase Chain Reaction; Receptor, Cannabinoid, CB1; RNA, Messenger; RNA, Viral; Signal Transduction; Up-Regulation; Virus Replication | 2014 |
Vagal anandamide signaling via cannabinoid receptor 1 contributes to luminal 5-HT modulation of visceral nociception in rats.
Topics: Adult; Animals; Arachidonic Acids; Cannabinoid Receptor Antagonists; Endocannabinoids; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Male; Middle Aged; Nociception; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Serotonin; Vagus Nerve; Visceral Pain | 2014 |
Cannabinoid-induced changes in respiration of brain mitochondria.
Topics: Animals; Arachidonic Acids; Benzoxazines; Brain; Cannabidiol; Cannabinoid Receptor Agonists; Cannabinoids; Cell Respiration; Dose-Response Relationship, Drug; Dronabinol; Drug Inverse Agonism; Endocannabinoids; Energy Metabolism; Mitochondria; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Signal Transduction; Swine | 2014 |
Anti-aversive role of the endocannabinoid system in the periaqueductal gray stimulation model of panic attacks in rats.
Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Behavior, Animal; Benzamides; Carbamates; Disease Models, Animal; Endocannabinoids; Enzyme Inhibitors; Male; N-Methylaspartate; Panic Disorder; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2015 |
The cannabinoid receptor antagonist AM251 increases paraoxon and chlorpyrifos oxon toxicity in rats.
Topics: Amidohydrolases; Analysis of Variance; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chlorpyrifos; Cholinesterase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Endocannabinoids; Insecticides; Male; Monoacylglycerol Lipases; Neurotoxicity Syndromes; Paraoxon; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Time Factors; Tritium | 2015 |
Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice.
Topics: Aggression; Agonistic Behavior; Animals; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Agonists; Corticosterone; Dose-Response Relationship, Drug; Endocannabinoids; Enzyme Inhibitors; Glycerides; Male; Metyrapone; Mice; Monoacylglycerol Lipases; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Signal Transduction | 2015 |
Role of endocannabinoid signalling in the dorsolateral periaqueductal grey in the modulation of distinct panic-like responses.
Topics: Animals; Arachidonic Acids; Benzamides; Carbamates; Disease Models, Animal; Dose-Response Relationship, Drug; Endocannabinoids; Escape Reaction; Male; Maze Learning; Panic Disorder; Periaqueductal Gray; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Signal Transduction | 2015 |
Blunted cardiac response to hemorrhage in cirrhotic rats is mediated by local macrophage-released endocannabinoids.
Topics: Animals; Arachidonic Acids; Blood Pressure; Cardiac Output; Endocannabinoids; Gadolinium; Glycerides; Hemorrhage; Liver Cirrhosis; Macrophages; Male; Monocytes; Myocardial Contraction; Myocardium; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Ventricular Function, Left | 2015 |
A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis.
Topics: Activating Transcription Factor 3; Amidohydrolases; Anilides; Animals; Arachidonic Acids; Benzamides; Capsaicin; Carbamates; Cinnamates; Disease Models, Animal; Endocannabinoids; Ganglia, Spinal; Gene Expression; Hyperalgesia; Inflammation; Interleukin-6; Lumbar Vertebrae; Male; Osteoarthritis; Pain; Pain Management; Pain Measurement; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2015 |
Endocannabinoid-mediated improvement on a test of aversive memory in a mouse model of fragile X syndrome.
Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Avoidance Learning; Benzamides; Cannabinoid Receptor Antagonists; Carbamates; Disease Models, Animal; Endocannabinoids; Enzyme Inhibitors; Fragile X Mental Retardation Protein; Fragile X Syndrome; Male; Memory; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Polyunsaturated Alkamides; Propofol; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, GABA-A; Social Behavior | 2015 |
Bi-directional CB1 receptor-mediated cardiovascular effects of cannabinoids in anaesthetized rats: role of the paraventricular nucleus.
Topics: Amidohydrolases; Anesthesia; Animals; Arachidonic Acids; Blood Pressure; Cannabinoids; Cerebral Cortex; Cyclohexanols; Endocannabinoids; Heart Rate; Male; Microinjections; Morpholines; Paraventricular Hypothalamic Nucleus; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2015 |
Modulatory effects by CB1 receptors on rat spinal locomotor networks after sustained application of agonists or antagonists.
Topics: Action Potentials; Animals; Arachidonic Acids; Endocannabinoids; gamma-Aminobutyric Acid; Locomotion; Nerve Net; Neural Inhibition; Neurons; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Reflex; Spinal Cord; Synaptic Transmission | 2015 |
Endocannabinoids, through opioids and prostaglandins, contribute to fever induced by key pyrogenic mediators.
Topics: Animals; Arachidonic Acids; beta-Endorphin; Body Temperature; Corticotropin-Releasing Hormone; Cytokines; Endocannabinoids; Endothelin-1; Fever; Interleukin-1beta; Interleukin-6; Male; Naloxone; Narcotic Antagonists; Piperidines; Polyunsaturated Alkamides; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Tumor Necrosis Factor-alpha | 2016 |
Anandamide mediates cognitive judgement bias in rats.
Topics: Acoustic Stimulation; Analysis of Variance; Animals; Arachidonic Acids; Benzamides; Bias; Calcium Channel Blockers; Carbamates; Cognition; Conditioning, Psychological; Cues; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Endocannabinoids; Judgment; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats | 2016 |
Endocannabinoid signaling mediates oxytocin-driven social reward.
Topics: Analysis of Variance; Animals; Arachidonic Acids; Autism Spectrum Disorder; Benzamides; Benzodiazepines; Camphanes; Carbamates; Clozapine; Cocaine; Endocannabinoids; Immunohistochemistry; Infusions, Intraventricular; Lipids; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Oxytocin; Piperazines; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Cannabinoid; Reward; Signal Transduction; Social Behavior | 2015 |
Cannabinoid receptor agonists modulate calcium channels in rat retinal Müller cells.
Topics: Animals; Arachidonic Acids; Benzoxazines; Calcium; Calcium Channels; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cells, Cultured; Dose-Response Relationship, Drug; Endocannabinoids; Ependymoglial Cells; Glycerides; Indoles; Male; Membrane Potentials; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant | 2016 |
Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Cell Line, Tumor; Cyclic AMP; Endocannabinoids; Genetic Predisposition to Disease; Glucagon-Like Peptide-1 Receptor; Glycerides; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice, Inbred C57BL; Mice, Knockout; Obesity; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1 | 2016 |
Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex-Possible involvement of 5-HT1A and CB1 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Arachidonic Acids; Behavior, Animal; Cannabidiol; Endocannabinoids; Male; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists | 2016 |
CB
Topics: Animals; Arachidonic Acids; Bicuculline; Disease Models, Animal; Endocannabinoids; Escape Reaction; GABA-A Receptor Antagonists; Male; Panic Disorder; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, GABA-A; TRPV Cation Channels; Ventromedial Hypothalamic Nucleus | 2017 |
Anandamide transporter-mediated regulation of the micturition reflex in urethane-anesthetized rats.
Topics: Administration, Intravenous; Anesthetics, Intravenous; Animals; Arachidonic Acids; Endocannabinoids; Female; Indoles; Membrane Transport Modulators; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reflex; Urethane; Urination; Urodynamics | 2016 |
A study of cannabinoid-1 receptors during the early phase of excitotoxic damage to rat spinal locomotor networks in vitro.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Disease Models, Animal; Endocannabinoids; Glycerides; Kainic Acid; Locomotion; Motor Neurons; Neural Pathways; Neuroprotection; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Spinal Cord; Spinal Cord Injuries; Tissue Culture Techniques | 2016 |
Anandamide reverses depressive-like behavior, neurochemical abnormalities and oxidative-stress parameters in streptozotocin-diabetic rats: Role of CB1 receptors.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Brain Chemistry; Calcium Channel Blockers; Depression; Diabetes Mellitus, Experimental; Endocannabinoids; Indoles; Male; Norepinephrine; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Serotonin; Swimming | 2016 |
Short-term inhibition of GABAergic IPSCs induced by association of pre- and postsynaptic activation in the neonatal hippocampus.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Calcium; Endocannabinoids; Excitatory Amino Acid Agents; Female; GABAergic Neurons; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Polyunsaturated Alkamides; Potassium; Presynaptic Terminals; Pyramidal Cells; Pyrazoles; Rats; Statistics, Nonparametric | 2017 |
AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids.
Topics: Amidohydrolases; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Arachidonic Acids; Cells, Cultured; Endocannabinoids; Female; Male; Mice; Mice, Knockout; Neurons; Nociception; Pain Measurement; Physical Conditioning, Animal; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Ribonucleotides | 2017 |
Cannabinoids Regulate the Diameter of Pericyte-Containing Retinal Capillaries in Rats.
Topics: Animals; Arachidonic Acids; Blotting, Western; Camphanes; Cannabinoid Receptor Antagonists; Cannabinoids; Capillaries; Endocannabinoids; Guanylate Cyclase; Immunohistochemistry; Male; Nitric Oxide Synthase; Pericytes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Cannabinoid; Retina; Rimonabant | 2017 |
Chronic treatment with URB597 ameliorates post-stress symptoms in a rat model of PTSD.
Topics: Amidohydrolases; Animals; Arachidonic Acids; Basolateral Nuclear Complex; Benzamides; Benzoxazines; CA1 Region, Hippocampal; Cannabinoid Receptor Antagonists; Carbamates; Dose-Response Relationship, Drug; Electric Stimulation; Endocannabinoids; Extinction, Psychological; Glycerides; Male; Morpholines; Naphthalenes; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Reflex, Startle; Stress Disorders, Post-Traumatic | 2018 |
Sexual interaction is essential for the transformation of non-copulating rats into sexually active animals by the endocannabinoid anandamide.
Topics: Animals; Arachidonic Acids; Brain; Cannabinoid Receptor Modulators; Dose-Response Relationship, Drug; Endocannabinoids; Male; Naloxone; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1; Sexual Behavior, Animal | 2019 |
Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia.
Topics: Amides; Animals; Arachidonic Acids; Cannabidiol; Disease Models, Animal; Endocannabinoids; Ethanolamines; Female; Glycerides; Hippocampus; Interpersonal Relations; Male; Methylazoxymethanol Acetate; Motor Activity; Oleic Acids; Palmitic Acids; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pregnancy; Prenatal Exposure Delayed Effects; Puberty; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Recognition, Psychology; RNA, Messenger; Schizophrenia | 2019 |
Anandamide Reduces the Toxic Synergism Exerted by Quinolinic Acid and Glutaric Acid in Rat Brain Neuronal Cells.
Topics: Animals; Arachidonic Acids; Benzamides; Cannabinoid Receptor Agonists; Carbamates; Cell Survival; Cells, Cultured; Cerebral Cortex; Drug Synergism; Endocannabinoids; Female; Glutarates; Male; Neurons; Piperidines; Polyunsaturated Alkamides; Pregnancy; Pyrazoles; Quinolinic Acid; Rats; Rats, Inbred WF; Receptors, Cannabinoid | 2019 |
Opposing roles of dorsomedial hypothalamic CB1 and TRPV1 receptors in anandamide signaling during the panic-like response elicited in mice by Brazilian rainbow Boidae snakes.
Topics: Animals; Arachidonic Acids; Boidae; Brazil; Cannabinoid Receptor Agonists; Dorsomedial Hypothalamic Nucleus; Dose-Response Relationship, Drug; Endocannabinoids; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Panic; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; TRPV Cation Channels | 2019 |
Role of the endocannabinoid system in the dorsal hippocampus in the cardiovascular changes and delayed anxiety-like effect induced by acute restraint stress in rats.
Topics: Amidohydrolases; Animals; Anxiety; Arachidonic Acids; Arterial Pressure; Behavior, Animal; Benzamides; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbamates; Disease Models, Animal; Endocannabinoids; Heart Rate; Hippocampus; Male; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Restraint, Physical; Skin Temperature; Stress, Psychological | 2019 |
Functional characterization of the cannabinoid receptors 1 and 2 in zebrafish larvae using behavioral analysis.
Topics: Animals; Arachidonic Acids; Cannabinoids; Dark Adaptation; Dose-Response Relationship, Drug; Endocannabinoids; Glycerides; Larva; Locomotion; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Zebrafish; Zebrafish Proteins | 2019 |
N‑linoleyltyrosine protects PC12 cells against oxidative damage via autophagy: Possible involvement of CB1 receptor regulation.
Topics: Adenine; Animals; Arachidonic Acids; Autophagy; Cell Survival; Endocannabinoids; Hydrogen Peroxide; Indoles; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Rats; Reactive Oxygen Species; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Tyrosine | 2020 |
The modulation of striatonigral and nigrotectal pathways by CB1 signalling in the substantia nigra pars reticulata regulates panic elicited in mice by urutu-cruzeiro lancehead pit vipers.
Topics: Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Corpus Striatum; Crotalinae; Endocannabinoids; Food Chain; Male; Mice; Mice, Inbred C57BL; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Panic; Pars Reticulata; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptor, Cannabinoid, CB1; Staining and Labeling; Superior Colliculi; Vesicular Inhibitory Amino Acid Transport Proteins | 2021 |