aluminum-magnesium-silicate and calcium-phosphate--dibasic--anhydrous

To investigate the tubule occlusion and remineralization potential of a novel toothpaste with active tetracalcium phosphate/monetite mixtures under de/remineralization cycling.. Dentin de/remineralization cycling protocol consisted of demineralization in 1% citric acid at pH 4.6 with following remineralization with toothpastes and soaking in artificial saliva. Effectiveness of toothpastes to promote remineralization was evaluated by measurement of microhardness recovery, analysis of surface roughness, thickness of coating and scanning electron microscopy.. The novel tetracalcium phosphate/monetite dentifrice had comparable remineralization potential as commercial calcium silicate/phosphate (SENSODYNE. The new fluoride toothpaste formulation with bioactive tetracalcium phosphate/monetite calcium phosphate mixture effectively occluded dentin tubules and showed good dentin remineralization potential under de/remineralization cycling. It could replace professional powder preparation based on this mixture. It was demonstrated that prepared dentifrice had comparable properties with commercial fluoride calcium silicate/phosphate or magnesium aluminum silicate dentifrices.

Topics: Aluminum Compounds; Calcium Phosphates; Dentin; Drug Combinations; Fluorides; Hardness Tests; Humans; In Vitro Techniques; Magnesium Compounds; Microscopy, Electron, Scanning; Nitrates; Phosphates; Saliva, Artificial; Silicates; Surface Properties; Tooth Remineralization; Toothpastes