altretamine and methotrexate

altretamine has been researched along with methotrexate in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199049 (74.24)18.7374
1990's9 (13.64)18.2507
2000's4 (6.06)29.6817
2010's4 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Carter, SK; Wasserman, TH1
Bitran, JD; Cooksey, JA; DeMeester, TR; Desser, RK; Golomb, HM; Mintz, U1
Anderson, T; Bender, RA; Canellos, GP; Chabner, BA; DeVita, VT; Fisher, RI; Hubbard, SP; Simon, RM; Young, RC1
Costa, J; Garvin, AJ; Ozols, RF; Simon, RM; Young, RC1
Blom, J; Heim, WJ; Miller, CF; Weltz, MD1
Weiss, RB1
Bruntsch, U; Gallmeier, WM2
Cunningham, T; Donavan, M; Longacre, D; Paladine, W; Sponzo, R1
Assekritova, IV; Gorbunova, VA; Lichinitser, MR1
Holoye, PY1
Fisher, RI; Young, RC1
DiBella, NJ; Nelson, RA; Norgard, MJ1
Canellos, GP; Chabner, BA; DeVita, VT; Hubbard, SP; Young, RC1
Young, RC2
Aartsen, E; Heintz, AP; Neijt, JP; ten Bokkel Huinink, WW; van der Burg, ME; van Lent, M; van Lindert, AC; van Oosterom, AT; Vermorken, JB; Willemse, PH1
Hansen, LA; Hughes, TE1
Neijt, JP; ten Bokkel Huinink, WW; van der Burg, ME; van der Hoop, RG; van Houwelingen, C1
Abeloff, MD; Aisner, SC; Eggleston, JC; Ettinger, DS; Finkelstein, DM; Ruckdeschel, JC1
Carbone, PP; Davis, TE; Kline, JC; Love, RR; Palta, M; Tormey, DC1
Bielack, S; Delling, G; Knop, J; Winkler, K1
Ihde, DC; Viallet, J1
Chahinian, AP; Comis, RL; Hirsh, V; Holland, JF; Kopel, S; Perry, MC; Propert, KJ; Skarin, A; Ware, JH; Zimmer, B1
Neijt, JP; ten Bokkel Huinink, WW; Van der Burg, ME; van Oosterom, AT1
Abeloff, MD; Berkman, AW; Markman, M; Waterfield, WC1
Livingston, RB1
Albain, KS; Bitran, JD; Desser, R; Golomb, HM; Greenburg, A; Hoffman, PC; Jacobs, RH; Potkul, L1
Ashikaga, T; Belinson, JL; McClure, M; Pretorius, RG1
Blouin, R; de Gramont, A; Dray, C; Drolet, Y; Krulik, M; Lavoie, A; Louvet, C; Painchaud, M; Pigné, A; Tessier, C1
Heintz, AP; Nooy, M; Schaberg, A; Trimbos, JB; Van der Velde, EA; Van Oosterom, AT1
Delgado, G; Edwards, BK; Marantz, AB; Posada, JG; Schein, PS; Smith, FP; Yeung, KY1
Howell, SB; Lucas, WE; Markman, M1
Ballard, WP; Coleman, M; Pasmantier, MW; Silver, RT1
Botts, B; Carlson, JA; Day, TG; Masterson, BJ1
Ozols, RF1
Grönroos, M; Kangas, L; Mäenpää, J1
Hamerlynck, JV; Kooyman, CD; Neijt, JP; ten Bokkel Huinink, WW; van der Burg, ME; van Houwelingen, JC; van Lent, M; van Lindert, AC; van Oosterom, AT; Vriesendorp, R1
Bertrand, M; Chang, FF; Kendregan, B; Klein, L; Mackie, A; Metter, GE; Multhauf, P; Presant, CA; Rappaport, D1
Carmo-Pereira, J; Costa, FO; Henriques, E; Ricardo, JA1
Kaplan, RS; Wiernik, PH1
Dillman, RO; Green, MR; Lea, JW; Lehar, TJ; Mendelsohn, J; Rentschler, RE; Royston, I; Seagren, SL; Stanton, W; Taetle, R; Young, JA1
Brissaud, P; de Gramont, A; Debray, J; Hubert, D; Krulik, M; Pigne, A; Sirinelli, A; Zylberait, D1
Bruckner, HW; Cohen, CJ; Goldberg, JD; Holland, JF1
Bruning, PF; Hamerlynck, JV; Schellekens, PT; ten Berge, RJ1
Berenberg, J; Comis, R; Green, M; Horton, C; Kennedy, BJ; Pajak, TF; Silver, RT; Spaulding, M1
Ozols, RF; Young, RC1
Davis, TE; Gilchrist, KW; Neville, AJ1
Chahinian, AP; Green, G; Holland, JF1
Barlow, JJ; Lele, SB1
Braun, DP; Harris, JE1
Grigorova, TM; Marenich, AF; Vartanian, LG1
De Lena, M; De Palo, G; Demicheli, R; Valagussa, P; Villa, E1
Postmus, PE; Smit, EF1
Heinonen, E; Hinkka, SM; Karnani, P; Klemi, PJ; Korpijaakko, TA; Kuoppala, TA; Lähde, MA; Laine, AM; Mäenpää, JU; Nuoranne, EK1
Broder, LE; Charyulu, KN; Donnelly, EJ; Rao, RK; Raub, WA; Saldana, MJ; Selawry, OS; Sridhar, KS1
Gray, RJ1
Green, MR1

Reviews

10 review(s) available for altretamine and methotrexate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The integration of chemotherapy into combined modality treatment of solid tumors. VIII. Cervical cancer.
    Cancer treatment reviews, 1977, Volume: 4, Issue:1

    Topics: Alkylating Agents; Altretamine; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Lymphatic Metastasis; Methotrexate; Radiotherapy, High-Energy; Radium; Uterine Cervical Neoplasms; Vaginal Smears

1977
Small-cell carcinoma of the lung: therapeutic management.
    Annals of internal medicine, 1978, Volume: 88, Issue:4

    Topics: Alkylating Agents; Altretamine; Antineoplastic Agents; Brain; Carcinoma, Small Cell; Doxorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Lung Neoplasms; Methotrexate; Nitrosourea Compounds; Podophyllotoxin; Procarbazine; Vinblastine; Vincristine

1978
Chemotherapy of ovarian cancer.
    The Surgical clinics of North America, 1978, Volume: 58, Issue:1

    Topics: Alkylating Agents; Altretamine; Cisplatin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms

1978
Chemotherapy of ovarian cancer: past and present.
    Seminars in oncology, 1975, Volume: 2, Issue:3

    Topics: Acrylates; Alkylating Agents; Altretamine; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Maryland; Methotrexate; Ovarian Neoplasms; Porfiromycin; Procarbazine; Progestins

1975
Hexamethylmelamine (altretamine): early National Cancer Institute trials.
    Cancer treatment reviews, 1991, Volume: 18 Suppl A

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; National Institutes of Health (U.S.); Neoplasm Staging; Ovarian Neoplasms; United States

1991
Altretamine.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Interactions; Female; Fluorouracil; Humans; Lung Neoplasms; Methotrexate; Ovarian Neoplasms

1991
Current chemotherapy of small cell lung cancer.
    Chest, 1986, Volume: 89, Issue:4 Suppl

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Combined Modality Therapy; Complement Membrane Attack Complex; Complement System Proteins; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mitomycin; Mitomycins; Podophyllotoxin; Procarbazine; Prognosis; Time Factors; Vincristine

1986
Chemotherapy of ovarian cancer.
    Seminars in oncology, 1984, Volume: 11, Issue:3

    Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Estrogen Antagonists; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Progestins; Tamoxifen

1984
Oral therapy for small cell lung cancer.
    Lung cancer (Amsterdam, Netherlands), 1995, Volume: 12 Suppl 3

    Topics: Administration, Oral; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Etoposide; Humans; Ifosfamide; Infusions, Intravenous; Lomustine; Lung Neoplasms; Methotrexate; Procarbazine

1995

Trials

24 trial(s) available for altretamine and methotrexate

ArticleYear
Hexamethylmelamine, bleomycin, and CCNU chemotherapy for patients with squamous cell carcinoma, large cell carcinoma, and adenocarcinoma of the lung unresponsive to cyclophosphamide, adriamycin, methotrexate, and procarbazine.
    Cancer treatment reports, 1978, Volume: 62, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Altretamine; Bleomycin; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Procarbazine; Triazines

1978
Advanced ovarian adenocarcinoma. A prospective clinical trial of melphalan (L-PAM) versus combination chemotherapy.
    The New England journal of medicine, 1978, Dec-07, Volume: 299, Issue:23

    Topics: Adenocarcinoma; Adult; Aged; Altretamine; Antineoplastic Agents; Cyclophosphamide; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Middle Aged; Ovarian Neoplasms; Prospective Studies

1978
Histologic grade in advanced ovarian cancer.
    Cancer treatment reports, 1979, Volume: 63, Issue:2

    Topics: Altretamine; Cell Differentiation; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Melphalan; Methotrexate; Ovarian Neoplasms; Prognosis

1979
Hexamethylmelamine, vincristine, and methotrexate chemotherapy in advanced neoplasms.
    Cancer treatment reports, 1977, Volume: 61, Issue:5

    Topics: Adult; Aged; Altretamine; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Neoplasms; Time Factors; Triazines; Vincristine

1977
Preliminary Results of trials of chemotherapy in advanced ovarian carcinoma.
    National Cancer Institute monograph, 1975, Volume: 42

    Topics: Altretamine; Antineoplastic Agents; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Maryland; Melphalan; Methotrexate; National Institutes of Health (U.S.); Ovarian Neoplasms; Prospective Studies; United States

1975
Long-term survival in ovarian cancer. Mature data from The Netherlands Joint Study Group for Ovarian Cancer.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:11

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Netherlands; Ovarian Neoplasms; Prognosis; Time Factors

1991
Hexamethylmelamine (altretamine): early National Cancer Institute trials.
    Cancer treatment reviews, 1991, Volume: 18 Suppl A

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cyclophosphamide; Female; Fluorouracil; Humans; Methotrexate; National Institutes of Health (U.S.); Neoplasm Staging; Ovarian Neoplasms; United States

1991
Incidence of neuropathy in 395 patients with ovarian cancer treated with or without cisplatin.
    Cancer, 1990, Oct-15, Volume: 66, Issue:8

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Nervous System Diseases; Ovarian Neoplasms; Prospective Studies

1990
A randomized comparison of standard chemotherapy versus alternating chemotherapy and maintenance versus no maintenance therapy for extensive-stage small-cell lung cancer: a phase III study of the Eastern Cooperative Oncology Group.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2

    Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Random Allocation; Remission Induction; Survival Rate; Vincristine

1990
[Scintigraphic follow-up of osteosarcoma during neoadjuvant chemotherapy. Results of the cooperative osteosarcoma study of the Society for Pediatric Oncology].
    Nuklearmedizin. Nuclear medicine, 1988, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Bone Neoplasms; Child; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Dactinomycin; Doxorubicin; Follow-Up Studies; Humans; Methotrexate; Multicenter Studies as Topic; Osteosarcoma; Radionuclide Imaging; Technetium Tc 99m Medronate

1988
A randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the Cancer and Leukemia Group B.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:8

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Prognosis; Random Allocation; Remission Induction; Warfarin

1989
Complete remission at laparotomy: still a gold standard in ovarian cancer?
    Lancet (London, England), 1986, May-03, Volume: 1, Issue:8488

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Laparotomy; Methotrexate; Ovarian Neoplasms; Random Allocation

1986
The case for combination chemotherapy in the treatment of advanced ovarian cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:11

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms

1985
Randomised trial comparing two combination chemotherapy regimens (Hexa-CAF vs CHAP-5) in advanced ovarian carcinoma.
    Lancet (London, England), 1984, Sep-15, Volume: 2, Issue:8403

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Paresthesia; Prognosis; Random Allocation; Reoperation; Time Factors

1984
Effects of amphotericin B with combination chemotherapy on response rates and on survival in non-small cell carcinoma of the lung.
    Cancer treatment reports, 1984, Volume: 68, Issue:4

    Topics: Altretamine; Amphotericin B; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Doxorubicin; Drug Evaluation; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Palliative Care; Random Allocation; Time Factors

1984
Advanced ovarian carcinoma: a prospective and randomized clinical trial of cyclophosphamide versus combination cytotoxic chemotherapy (Hexa-CAF).
    Cancer, 1981, Nov-01, Volume: 48, Issue:9

    Topics: Adenocarcinoma, Mucinous; Adult; Aged; Altretamine; Antineoplastic Agents; Carcinoma; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Prognosis; Prospective Studies

1981
Improved therapy with cisplatin regimens for patients with ovarian carcinoma (FIGO III and IV) as measured by surgical end-staging (second-look surgery)--the mount sinai experience.
    Clinics in obstetrics and gynaecology, 1983, Volume: 10, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Random Allocation; Reoperation; Thiotepa

1983
Combination chemotherapy and immune capacity in advanced ovarian carcinoma.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:1

    Topics: Adult; Aged; Altretamine; Antibody Formation; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Cytotoxicity, Immunologic; Doxorubicin; Female; Fluorouracil; Humans; Immunity, Cellular; Leukocyte Count; Lymphocyte Activation; Methotrexate; Middle Aged; Ovarian Neoplasms

1984
Four-drug combination chemotherapy (methotrexate, cyclophosphamide, hexamethylmelamine, and CCNU) for non-small cell bronchogenic carcinoma: a Cancer and Leukemia Group B study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1983, Volume: 1, Issue:9

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate

1983
Mitomycin-C, etoposide, cisplatin, and hexamethylmelamine (MEPH) as a second-line regimen in lung cancer.
    American journal of clinical oncology, 1984, Volume: 7, Issue:5

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Leukopenia; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Mitomycins; Neoplasm Metastasis; Thrombocytopenia; Vomiting

1984
Cisplatin-MECY (methotrexate-leucovorin rescue plus cyclophosphamide) versus cisplatin-CHAD (cyclophosphamide, hexamethylmelamine, doxorubicin, and cisplatin) as initial chemotherapy in stage III-IV ovarian adenocarcinoma.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Adenocarcinoma; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Humans; Leucovorin; Methotrexate; Neoplasm Staging; Ovarian Neoplasms

1984
Medical Research Council study on chemotherapy in advanced ovarian cancer. Medical Research Council's Working Party on ovarian cancer.
    British journal of obstetrics and gynaecology, 1981, Volume: 88, Issue:12

    Topics: Aged; Altretamine; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Random Allocation

1981
The subrenal capsule assay in selecting chemotherapy for ovarian cancer: a prospective randomized trial.
    Gynecologic oncology, 1995, Volume: 57, Issue:3

    Topics: Aged; Altretamine; Animals; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Carboplatin; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Female; Humans; Methotrexate; Mice; Mice, Inbred Strains; Middle Aged; Ovarian Neoplasms; Prospective Studies; Subrenal Capsule Assay; Tegafur

1995
A randomized clinical trial in bronchogenic small-cell carcinoma evaluating alternating maintenance therapy of vincristine, adriamycin, procarbazine, and etoposide (VAPE) with cyclophosphamide, CCNU, and methotrexate (CCM) versus CCM maintenance alone in
    American journal of clinical oncology, 1994, Volume: 17, Issue:6

    Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Mitomycin; Procarbazine; Remission Induction; Vinblastine; Vincristine

1994

Other Studies

33 other study(ies) available for altretamine and methotrexate

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Six-drug combination chemotherapy for nonresectable bronchogenic carcinoma.
    Cancer treatment reports, 1979, Volume: 63, Issue:8

    Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Carcinoma, Bronchogenic; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Procarbazine

1979
[Chemotherapy of the ovarian carcinoma (author's transl)].
    Strahlentherapie, 1977, Volume: 153, Issue:5

    Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxyprogesterones; Mechlorethamine; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Nitrosourea Compounds; Ovarian Neoplasms; Thiotepa; Vinblastine; Vincristine

1977
[Carminomycin in drug combination in breast cancer and soft tissue sarcomas].
    Antibiotiki, 1977, Volume: 22, Issue:10

    Topics: Aged; Altretamine; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cyclophosphamide; Drug Therapy, Combination; Female; Humans; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Metastasis; Sarcoma; Soft Tissue Neoplasms

1977
Management of small-cell bronchogenic carcinoma.
    Comprehensive therapy, 1978, Volume: 4, Issue:2

    Topics: Altretamine; Antibiotics, Antineoplastic; Brain Neoplasms; Carcinoma, Bronchogenic; Cyclophosphamide; Drug Therapy, Combination; Humans; Lung Neoplasms; Mechlorethamine; Methotrexate; Neoplasm Metastasis; Pleural Effusion; Prognosis; Vena Cava, Superior

1978
Combination chemotherapy with CCNU (NSC-79037),hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in advanced bronchogenic carcinoma.
    Oncology, 1975, Volume: 32, Issue:2

    Topics: Aged; Altretamine; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Drug Evaluation; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nitrosourea Compounds; Remission, Spontaneous; Tracheal Neoplasms; Triazines

1975
Short term high density systemic therapy for metastatic breast cancer.
    Breast cancer research and treatment, 1985, Volume: 5, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Bleomycin; Breast Neoplasms; Combined Modality Therapy; Doxorubicin; Drug Administration Schedule; Female; Fluoxymesterone; Humans; Leucovorin; Leukopenia; Lung; Methotrexate; Mitolactol; Neoplasm Metastasis; Prednisone; Receptors, Estrogen; Tamoxifen; Thrombocytopenia; Time Factors; Vincristine

1985
Systemic therapy for small-cell lung cancer: old themes replayed, new ones awaited.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1989, Volume: 7, Issue:8

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Doxorubicin; Etoposide; Humans; Lomustine; Lung Neoplasms; Methotrexate; Mitomycin; Mitomycins

1989
Intensive alternating chemotherapy regimen in small cell carcinoma of the lung.
    Cancer treatment reports, 1985, Volume: 69, Issue:2

    Topics: Actuarial Analysis; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Brain Neoplasms; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Etoposide; Female; Gastrointestinal Hemorrhage; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Thrombocytopenia; Vincristine

1985
A 10-year experience with combined modality therapy for stage III small cell lung carcinoma.
    Cancer, 1986, Nov-15, Volume: 58, Issue:10

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Prognosis; Vincristine

1986
Hexamethylmelamine, methotrexate, 5-fluorouracil as second line chemotherapy after platinum for epithelial ovarian malignancies.
    Gynecologic oncology, 1986, Volume: 23, Issue:3

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Hormones; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Peptichemio

1986
[Chemotherapy in 143 advanced epithelial cancers of the ovary. Experience at the Hôtel-Dieu of Quebec and Hôpital Saint-Antoine (Paris)].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 1986, Volume: 15, Issue:1

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Neoplasm Staging; Ovarian Neoplasms

1986
The treatment of advanced ovarian carcinoma (I): clinical variables associated with prognosis.
    Gynecologic oncology, 1988, Volume: 30, Issue:3

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Cisplatin; Combined Modality Therapy; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Hysterectomy; Methotrexate; Ovarian Neoplasms; Ovariectomy; Postoperative Care; Prognosis; Regression Analysis

1988
The cyclophosphamide, hexamethylmelamine, 5 fluorouracil (CHF) regimen in the treatment of advanced and recurrent ovarian cancer.
    Gynecologic oncology, 1985, Volume: 20, Issue:1

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclophosphamide; Drug Evaluation; Female; Fluorouracil; Humans; Hysterectomy; Lymphatic Metastasis; Methotrexate; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Reoperation

1985
Intraperitoneal chemotherapy for advanced ovarian cancer.
    American journal of obstetrics and gynecology, 1985, Jun-15, Volume: 152, Issue:4

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Administration Schedule; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Peritoneal Cavity; Thiosulfates

1985
Six-drug chemotherapy (hexamethylmelamine, doxorubicin, cisplatin, cyclophosphamide, methotrexate, and 5-FU; CHAMP-5) for ovarian carcinoma: alternating sequences of combination regimens.
    Cancer treatment reports, 1985, Volume: 69, Issue:6

    Topics: Adenocarcinoma; Age Factors; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms

1985
Hexamethylmelamine, methotrexate and 5-fluorouracil (HMF) for progressive ovarian carcinoma during therapy with cis-platinum, cyclophosphamide +/- doxorubicin.
    Gynecologic oncology, 1985, Volume: 22, Issue:2

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Drug Resistance; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Reoperation

1985
Response of ovarian cancer to combined cytotoxic agents in the subrenal capsule assay: Part I.
    Obstetrics and gynecology, 1985, Volume: 66, Issue:5

    Topics: Aclarubicin; Adolescent; Adult; Aged; Altretamine; Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; Cystadenocarcinoma; Doxorubicin; Epirubicin; Etoposide; Female; Humans; Methotrexate; Mice; Middle Aged; Mitomycins; Naphthacenes; Neoplasm Transplantation; Ovarian Neoplasms; Tegafur; Tumor Stem Cell Assay; Vincristine

1985
Neurotoxicity of antineoplastic drugs.
    Seminars in oncology, 1982, Volume: 9, Issue:1

    Topics: Altretamine; Antineoplastic Agents; Asparaginase; Brain; Central Nervous System Diseases; Cisplatin; Cranial Nerves; Humans; Injections, Intraventricular; Injections, Spinal; Methotrexate; Peripheral Nervous System Diseases; Procarbazine; Risk; Tomography, X-Ray Computed; Vinca Alkaloids

1982
Non-cross-resistant chemotherapy and consolidation radiotherapy for small cell carcinoma of the lung.
    Cancer treatment reports, 1982, Volume: 66, Issue:6

    Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Carcinoma, Small Cell; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Humans; Lung Neoplasms; Male; Methotrexate; Middle Aged; Prognosis; Vincristine

1982
[Treatment of advanced ovarian cancer].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1984, Mar-29, Volume: 60, Issue:14

    Topics: Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Follow-Up Studies; Humans; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prognosis

1984
[Chemotherapy of epithelial ovarian carcinoma].
    MMW, Munchener medizinische Wochenschrift, 1983, Nov-04, Volume: 125, Issue:44

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms

1983
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
    Medical and pediatric oncology, 1984, Volume: 12, Issue:6

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Granulosa Cell Tumor; Humans; Melphalan; Methotrexate; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Prednisone; Retrospective Studies; Vincristine

1984
Effects of combination chemotherapy on immunoregulatory cells in peripheral blood of solid tumor cancer patients: correlation with rebound overshoot immune function recovery.
    Clinical immunology and immunopathology, 1981, Volume: 20, Issue:2

    Topics: Adult; Aged; Altretamine; Antineoplastic Agents; Cell Adhesion; Drug Therapy, Combination; Fluorouracil; Humans; Immunity, Cellular; Indomethacin; Leucovorin; Lymphocyte Activation; Methotrexate; Middle Aged; Mitomycins; Monocytes; Neoplasms; Phytohemagglutinins; T-Lymphocytes, Regulatory; Time Factors

1981
[Surgical method and combination chemotherapy in treating stage-III and IV ovarian cancer].
    Voprosy onkologii, 1980, Volume: 26, Issue:2

    Topics: Altretamine; Antineoplastic Agents; Carcinoma; Cyclophosphamide; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Fluorouracil; Humans; Methotrexate; Ovarian Neoplasms; Ovary; Postoperative Care; Tegafur; Time Factors

1980
Prospective study with HEXA-CAF combination in ovarian carcinoma.
    Cancer chemotherapy and pharmacology, 1981, Volume: 5, Issue:3

    Topics: Altretamine; Antineoplastic Agents; Cyclophosphamide; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Ovarian Neoplasms; Ovary

1981
A Bayesian analysis of institutional effects in a multicenter cancer clinical trial.
    Biometrics, 1994, Volume: 50, Issue:1

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Bayes Theorem; Biometry; Carcinoma, Small Cell; Cyclophosphamide; Data Interpretation, Statistical; Doxorubicin; Etoposide; Humans; Lung Neoplasms; Methotrexate; Multicenter Studies as Topic; Probability; Proportional Hazards Models; Randomized Controlled Trials as Topic; Vincristine

1994
Lessons from a time capsule: evolution, not revolution, in therapy for advanced non-small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jul-01, Volume: 26, Issue:19

    Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Bronchogenic; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase II as Topic; Cyclophosphamide; Female; Humans; Lomustine; Lung Neoplasms; Male; Methotrexate; Research Design

2008