alrestatin and tolrestat

alrestatin has been researched along with tolrestat in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abraham, N; Bellini, F; Dvornik, D; Fung, S; Humber, L; Sestanj, K; Simard-Duquesne, N; Treasurywala, A1
Ansari, NH; Bhatnagar, A; Das, B; Liu, SQ; Srivastava, SK1
Humber, LG1
Burnakis, TG; Tsai, SC1
Gelber, DA; Pfeifer, MA; Schumer, MP1

Reviews

3 review(s) available for alrestatin and tolrestat

ArticleYear
The medicinal chemistry of aldose reductase inhibitors.
    Progress in medicinal chemistry, 1987, Volume: 24

    Topics: Aldehyde Reductase; Animals; Flavonoids; Humans; Hydantoins; Isoquinolines; Naphthalenes; Sugar Alcohol Dehydrogenases

1987
Aldose reductase inhibitors: an update.
    The Annals of pharmacotherapy, 1993, Volume: 27, Issue:6

    Topics: Aldehyde Reductase; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines

1993
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
    Diabetes, 1997, Volume: 46 Suppl 2

    Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines; Time Factors

1997

Trials

1 trial(s) available for alrestatin and tolrestat

ArticleYear
Aldose reductase inhibitors: the end of an era or the need for different trial designs?
    Diabetes, 1997, Volume: 46 Suppl 2

    Topics: Aldehyde Reductase; Autonomic Nervous System; Diabetic Neuropathies; Enzyme Inhibitors; Humans; Imidazoles; Imidazolidines; Isoquinolines; Naphthalenes; Phthalazines; Time Factors

1997

Other Studies

2 other study(ies) available for alrestatin and tolrestat

ArticleYear
N-[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]thioxomethyl]- N-methylglycine (Tolrestat), a potent, orally active aldose reductase inhibitor.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:3

    Topics: Aldehyde Reductase; Animals; Cattle; Diabetes Mellitus, Experimental; Galactitol; Isoquinolines; Lens, Crystalline; Naphthalenes; Rats; Sorbitol; Sugar Alcohol Dehydrogenases

1984
Inhibition kinetics of human kidney aldose and aldehyde reductases by aldose reductase inhibitors.
    Biochemical pharmacology, 1990, Mar-15, Volume: 39, Issue:6

    Topics: Aldehyde Reductase; Aldehydes; Carbohydrate Dehydrogenases; Chromones; Humans; Imidazoles; Imidazolidines; Isoquinolines; Kidney; Kinetics; Naphthalenes; Phenobarbital; Phthalazines; Quercetin; Quinolones; Substrate Specificity; Sugar Alcohol Dehydrogenases

1990