alprostadil and butaprost

alprostadil has been researched along with butaprost* in 1 studies

Other Studies

1 other study(ies) available for alprostadil and butaprost

Article	Year
Design and synthesis of a highly selective EP2-receptor agonist. Bioorganic & medicinal chemistry letters, 2001, Aug-06, Volume: 11, Issue:15 EP2-receptor selective agonist 3 was identified by the structural hybridization of butaprost 1a and PGE(2) 2a. Based on this information, a chemically more stabilized 4 was discovered as another highly selective EP2-receptor agonist, iv administration of which to anesthetized rats suppressed uterine motility, while PGE(2) 2a stimulated uterine motility. Topics: Alprostadil; Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Cyclobutanes; Cyclopentanes; Dinoprostone; Drug Design; Female; Humans; Ligands; Mice; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Sensitivity and Specificity; Uterine Contraction	2001

Article

Year

Design and synthesis of a highly selective EP2-receptor agonist.

Bioorganic & medicinal chemistry letters, 2001, Aug-06, Volume: 11, Issue:15

EP2-receptor selective agonist 3 was identified by the structural hybridization of butaprost 1a and PGE(2) 2a. Based on this information, a chemically more stabilized 4 was discovered as another highly selective EP2-receptor agonist, iv administration of which to anesthetized rats suppressed uterine motility, while PGE(2) 2a stimulated uterine motility.

Topics: Alprostadil; Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Cyclobutanes; Cyclopentanes; Dinoprostone; Drug Design; Female; Humans; Ligands; Mice; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; Sensitivity and Specificity; Uterine Contraction

2001