alprenolol has been researched along with practolol in 102 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 86 (84.31) | 18.7374 |
1990's | 4 (3.92) | 18.2507 |
2000's | 7 (6.86) | 29.6817 |
2010's | 5 (4.90) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Eckelman, WC; Gibson, RE; Reba, RC; Rzeszotarski, WJ | 1 |
Bultsma, T; Donné-Op den Kelder, GM; Rademaker, B; Timmerman, H | 1 |
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H | 1 |
Artursson, P; Beigi, F; Lundahl, P; Luthman, K; Palm, K; Strandlund, G; Ungell, AL | 1 |
Ghuloum, AM; Jain, AN; Sage, CR | 1 |
Ertl, P; Rohde, B; Selzer, P | 1 |
Artursson, P; Luthman, K; Norinder, U; Stenberg, P | 1 |
Baker, JG | 1 |
Caron, G; Ermondi, G | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Akamatsu, M | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
Pfeifer, S; Zimmer, C | 1 |
Maekawa, H; Sekiya, A; Yamamoto, J | 1 |
Miesch, F; Schwartz, J; Spach, MO | 1 |
Norris, RM | 1 |
Levy, JV | 1 |
Harry, JD | 1 |
Fitzgerald, JD | 1 |
Hansson, L; Werkö, L | 1 |
Frisk-Holmberg, M; Ostman, J | 1 |
Himori, N; Hiramatsu, Y; Ishimori, T; Izumi, A | 1 |
Meier, J | 1 |
Darabi, MK; Hague, MA; Khalighi, MR | 1 |
Pöntinen, PJ | 1 |
Eckelman, WC; Gibson, RE; Jiang, VW; Reba, RC; Rzeszotarski, WJ | 1 |
Day, MD; Roach, AG | 2 |
Chamberlain, DA | 1 |
Wilkinson, RK | 1 |
Kiechel, JR; Meier, J | 1 |
Fanchamps, A | 1 |
Tannenbaum, H | 1 |
de Vente, J; Harms, HH; Zaagsma, J | 1 |
Malchoff, CD; Marinetti, GV | 1 |
Dietz, J; Kaiser, G; Palm, D; Wiemer, G | 1 |
Doshchitsin, VL | 1 |
Baker, I; Das Gupta, DS; Sowton, E | 1 |
Boissier, JR; Giudicelli, JF; Lhoste, F | 1 |
Dubach, UC | 1 |
Elonen, E | 1 |
Ekelund, LG; Orö, L | 1 |
Himori, N; Ishimori, T; Izumi, A | 1 |
Prichard, BN | 2 |
Hoshino, T; Kin, K; Kinoshita, M; Shimono, Y; Tomonaga, G | 1 |
Fujita, T; Miyazaki, M; Nioka, S | 1 |
Hjalmarson, A; Varnauskas, E; Waagstein, F; Wallentin, I | 2 |
Vedin, JA; Wilhelmsson, CE | 1 |
Abrmets, II; Simon, IB | 1 |
Jancinová, V; Nosál, R; Petríková, M | 1 |
Fernández-Guasti, A; Rodríguez-Manzo, G | 1 |
Cheetham, SC; Crompton, MR; De Paermentier, F; Horton, RW | 1 |
Fishbein, L; Jackson, CD | 1 |
Abrahamsson, T | 1 |
Mottot, G; Romero-Ferret, C; Rosner, I | 1 |
Turner, P | 1 |
Bender, F; Bräuer, B; Brisse, B; Gradaus, D; Müller, W | 1 |
Singh, BN | 1 |
Offerhaus, L | 1 |
Bagwell, EE; Williams, EM | 1 |
Gibson, DG | 1 |
Beumer, HM | 1 |
Ablad, B; Carlsson, B; Carlsson, E; Dahlöf, C; Ek, L; Hultberg, E | 1 |
Furberg, CD | 1 |
Simpson, FO | 1 |
Baïsset, A; Montastruc, P | 1 |
Almgren, O; Jonason, J | 1 |
Jewitt, DE; Singh, BN | 1 |
Advenier, C; Boissier, JR; Dumas, Y; Giudicelli, JF | 1 |
Cottier, P | 1 |
Horii, D; Imai, S; Kawada, T; Takeda, K | 1 |
Walle, T | 1 |
Cazard, JC; Couderc, JJ; Marco, J; Salvador, M | 1 |
Aberg, A; Ulvenstam, G; Vedin, A; Wilhelmsson, C | 1 |
Naess, K | 1 |
Cash, JD; Da Costa, J; Gader, AM | 1 |
Frishman, WH | 1 |
Eckelman, WC; Francis, B; Gibson, RE; Reba, RC; Rzeszotarski, WJ; Vieras, F | 1 |
Schröder, R | 1 |
Hampton, JR | 2 |
Le Douarec, JC; Lotti, VJ; Schmitt, C | 1 |
Vedin, A; Wilhelmsson, C | 1 |
Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP | 1 |
Frick, MH; Katila, M | 1 |
Hjalmarson, A | 1 |
Helfert, I; Mácová, S; Trcka, V; Vanĕcek, M | 1 |
Siblíková, O; Trcka, V | 1 |
Gabrielsson, M; Heath, A; Redgårdh, CG | 1 |
Pratt, CM; Roberts, R | 1 |
Friedewald, WT; Frishman, WH; Furberg, CD | 2 |
Tomov, I | 1 |
Kerry, R; Scrutton, MC | 1 |
Bruynzeel, PL; de Jong, JG; Hamelink, ML; Kok, PT | 1 |
23 review(s) available for alprenolol and practolol
Article | Year |
---|---|
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1988 |
[Biotransformation and pharmacokinetics of beta-receptor blockaders].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Biotransformation; Ethanolamines; Humans; Isoproterenol; Kinetics; Levobunolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Sotalol | 1975 |
Beta-adrenergic blockade in hypertension.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Brain; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemodynamics; Humans; Hypertension; Kidney Function Tests; Practolol; Propranolol; Renin | 1977 |
[Comparative pharmacokinetics of beta-blockers].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol | 1978 |
[Preventive effects of beta-blockers on myocardial infarction and on cardiac accidents following a first infarct].
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Humans; Hypertension; Middle Aged; Myocardial Infarction; Practolol; Prospective Studies | 1978 |
[Long-term utilization of beta-blockers in arterial hypertension].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Tolerance; Heart Rate; Humans; Hypertension; Metoprolol; Pindolol; Practolol; Time Factors | 1978 |
Propranolol in the treatment of angina: a review.
Topics: Alprenolol; Angina Pectoris; Dose-Response Relationship, Drug; Heart Rate; Humans; Isosorbide; Practolol; Propranolol; Sotalol | 1976 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
Beta-adrenergic receptor blocking drugs in hyperthyroidism.
Topics: Adrenergic beta-Antagonists; Alprenolol; Antithyroid Agents; Ethanolamines; Humans; Hyperthyroidism; Iodine Radioisotopes; Oxprenolol; Pindolol; Practolol; Premedication; Propranolol; Sotalol; Sympathomimetics; Thyroidectomy | 1974 |
[Clinical application of beta-blockaders].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Anxiety Disorders; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Humans; Hypertension; Hyperthyroidism; Oxprenolol; Pindolol; Practolol; Propranolol | 1973 |
Pharmacodynamic properties of beta-adrenergic receptor blocking drugs in man.
Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Cardiac Output; Catecholamines; Glycolysis; Heart; Heart Conduction System; Heart Rate; Hemodynamics; Humans; Lipid Metabolism; Oxprenolol; Oxygen Consumption; Physical Exertion; Pindolol; Practolol; Propranolol; Quinidine; Receptors, Adrenergic; Regional Blood Flow; Renin; Structure-Activity Relationship; Vasomotor System | 1974 |
Beta-adrenergic receptor blocking drugs in angina pectoris.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Ethanolamines; Exercise Test; Heart Rate; Humans; Oxprenolol; Oxygen Consumption; Physical Exertion; Pindolol; Practolol; Propranolol; Sotalol | 1974 |
Adverse effects of beta-adrenergic receptor blocking drugs on respiratory function.
Topics: Adrenergic beta-Antagonists; Alprenolol; Asthma; Bronchi; Bronchial Spasm; Humans; Isoproterenol; Muscle, Smooth; Oxprenolol; Pindolol; Practolol; Propranolol; Respiration | 1974 |
Beta-adrenergic receptor blocking drugs in hypertrophic cardiomyopathy, autonomically mediated cardiovascular functional disorders and Fallot's tetralogy.
Topics: Adrenergic beta-Antagonists; Alprenolol; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Drug Evaluation; Heart Rate; Humans; Oxprenolol; Pindolol; Placebos; Practolol; Propranolol; Tetralogy of Fallot | 1974 |
Beta-adrenergic receptor blocking drugs in hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Antidepressive Agents; Antihypertensive Agents; Asthma; Diuretics; Drug Evaluation; Drug Therapy, Combination; Ganglionic Blockers; Heart Failure; Humans; Hypertension; Libido; Oxprenolol; Pindolol; Practolol; Propranolol; Psychopharmacology; Regional Blood Flow; Sotalol; Vasodilator Agents | 1974 |
Beta-adrenergic receptor blocking drugs in cardiac arrhythmias.
Topics: Action Potentials; Adrenergic beta-Antagonists; Alprenolol; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Surgical Procedures; Catecholamines; Depression, Chemical; Digitalis Glycosides; Electrocardiography; Humans; Myocardial Infarction; Oxprenolol; Pacemaker, Artificial; Pindolol; Practolol; Propranolol; Purkinje Fibers; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation; Wolff-Parkinson-White Syndrome | 1974 |
Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 12. Beta-adrenoceptor blockade in myocardial infarction: the continuing controversy.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Double-Blind Method; Humans; Myocardial Infarction; Placebos; Practolol | 1980 |
[Secondary prevention following myocardial infarct. Platelet aggregation inhibitors, beta receptor blockers, antiarrhythmics].
Topics: Adrenergic beta-Antagonists; Alprenolol; Anti-Arrhythmia Agents; Aspirin; Dipyridamole; Female; Fibrinolytic Agents; Humans; Male; Myocardial Infarction; Phenprocoumon; Platelet Aggregation; Practolol; Propranolol; Recurrence; Sex Factors; Sulfinpyrazone; Time Factors | 1981 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
16 trial(s) available for alprenolol and practolol
Article | Year |
---|---|
Evaluation of intrinsic sympathomimetic activity of beta-adrenoceptor blocking drugs in the treatment of patients with angina pectoris.
Topics: Acute Disease; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Exercise Test; Hemodynamics; Humans; Nitroglycerin; Pindolol; Practolol; Propranolol; Sympathomimetics | 1976 |
Beta-adrenergic blocking agents in prevention of sudden death.
Topics: Acute Disease; Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Death, Sudden; Drug Evaluation; Humans; Myocardial Infarction; Placebos; Practolol | 1978 |
[Preventive effects of beta-blockers on myocardial infarction and on cardiac accidents following a first infarct].
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Humans; Hypertension; Middle Aged; Myocardial Infarction; Practolol; Prospective Studies | 1978 |
Comparative effects of beta adrenergic blocking drugs.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Clinical Trials as Topic; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Injections, Intravenous; Oxprenolol; Pindolol; Placebos; Practolol; Propranolol; Sotalol | 1975 |
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study.
Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Placebos; Practolol; Pyridines | 1979 |
[New viewpoints on the effect of beta-receptor blockaders].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Heart Failure; Humans; Male; Norepinephrine; Physical Exertion; Practolol; Verapamil | 1973 |
[Treatment of arterial hypertension using beta-blockaders].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Drug Evaluation; Humans; Hypertension; Oxprenolol; Pindolol; Practolol; Propranolol | 1974 |
Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 12. Beta-adrenoceptor blockade in myocardial infarction: the continuing controversy.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Double-Blind Method; Humans; Myocardial Infarction; Placebos; Practolol | 1980 |
The use of beta blockers for the reduction of mortality after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Myocardial Infarction; Norway; Oxprenolol; Practolol; Propranolol; Random Allocation; Timolol | 1981 |
Beta blockade and the secondary prevention of myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Practolol; Recurrence | 1981 |
Beta blockers after myocardial infarction--aspects on study design based on current knowledge.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Myocardial Infarction; Practolol; Timolol | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol | 1982 |
Chronic beta blockade therapy in patients after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol | 1983 |
Beta-adrenergic blockade for survivors of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Coronary Disease; Follow-Up Studies; Humans; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Time Factors; Timolol | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol | 1984 |
70 other study(ies) available for alprenolol and practolol
Article | Year |
---|---|
Cardioselectivity of beta-adrenoceptor blocking agents 1. 1-[(4-Hydroxyphenethyl)amino]-3-(aryloxy)propan-2-ols.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Binding, Competitive; Heart; In Vitro Techniques; Lung; Myocardium; Organ Specificity; Propanolamines; Rats; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1979 |
Mapping of the beta 2-adrenoceptor on Chang liver cells. Differences between high- and low-affinity receptor states.
Topics: Cell Membrane; Cells, Cultured; Guanylyl Imidodiphosphate; Hydrogen Bonding; Iodocyanopindolol; Liver; Models, Molecular; Pindolol; Protein Conformation; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Stereoisomerism; Structure-Activity Relationship | 1988 |
Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors.
Topics: Adrenergic beta-Antagonists; Amides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Drug Design; Epithelial Cells; Formamides; Humans; Intestinal Absorption; Liposomes; Models, Molecular; Molecular Conformation; Monte Carlo Method; Permeability; Propanolamines; Structure-Activity Relationship | 1998 |
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules.
Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship | 1999 |
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties.
Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results | 2000 |
Experimental and computational screening models for the prediction of intestinal drug absorption.
Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil | 2001 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Effects of several beta-blockers on blood pressure in the rat.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Epinephrine; Female; Heart Atria; Heart Rate; Male; Myocardial Contraction; Pindolol; Practolol; Propranolol; Rats | 1975 |
[Comparison of the pA2 of various beta blocking agents].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; In Vitro Techniques; Oxprenolol; Pindolol; Practolol; Propranolol; Trachea | 1975 |
Prophylactic antiarrhythmic drugs after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Age Factors; Alprenolol; Anti-Arrhythmia Agents; Humans; Middle Aged; Myocardial Infarction; Practolol; Quinidine; Recurrence | 1976 |
Beta-adrenergic receptor blocking drugs in spontaneous hypertension.
Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors | 1976 |
The effect of beta-adrenoreceptive antagonists on the morbidity and mortality in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Animals; Coronary Disease; Dogs; Follow-Up Studies; Humans; Myocardial Infarction; Practolol; Propranolol; Substance Withdrawal Syndrome | 1976 |
Differential inhibition of lipolysis in human adipose tissue by adrenergic beta receptor blocking drugs.
Topics: Adipose Tissue; Adrenergic beta-Antagonists; Albuterol; Alprenolol; Dose-Response Relationship, Drug; Female; Glycerol; Humans; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Practolol; Propranolol; Theophylline | 1977 |
Effects of beta-adrenoceptor blocking agents, pindolol, alprenolol and practolol on blood pressure and heart rate in conscious renal hypertensive dogs.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dogs; Drug Interactions; Heart Rate; Hypertension, Renal; Injections, Intravenous; Isoproterenol; Pindolol; Practolol; Propanolamines; Time Factors | 1977 |
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents.
Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol | 1977 |
Comparative study of beta andreoceptor antagonists on the isolated atria of control and of the reserpine treated rabbits.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arrhythmias, Cardiac; Female; Heart Atria; Heart Rate; Isoproterenol; Male; Oxprenolol; Practolol; Propranolol; Rabbits; Reserpine | 1977 |
Cardiovascular effects of local adrenaline infiltration during halothane anaesthesia and adrenergic beta-receptor blockade in man.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alprenolol; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Child; Epinephrine; Female; Halothane; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Practolol; Propranolol | 1978 |
Radioiodinated derivatives of beta adrenoceptor blockers for myocardial imaging.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Heart; Iodine Radioisotopes; Myocardium; Practolol; Radionuclide Imaging; Rats | 1978 |
The brain as a possible site for the cardiovascular effects of beta-adrenoceptor blocking agents in cats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Blood Pressure; Brain; Cats; Female; Heart Rate; Injections, Intraventricular; Male; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol | 1975 |
The role of long term beta-blockade after myocardial infarction: Paper 3.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Humans; Myocardial Infarction; Practolol; Time Factors | 1978 |
Differentiation of beta-adrenoceptors in right atrium, diaphragm and adipose tissue of the rat, using stereoisomers of propranolol, alprenolol, nifenalol and practolol.
Topics: Adipose Tissue; Alprenolol; Animals; Diaphragm; Ethanolamines; Heart Atria; Male; Myocardium; Organ Specificity; Practolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Stereoisomerism; Structure-Activity Relationship | 1977 |
Hormone action at the membrane level. VI. Binding of (-)-[3H]dihydroalprenolol and (+/-)-[3H]isoproterenol to turkey erythrocytes and correlation with adenylate cyclase activity.
Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Female; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Turkeys | 1978 |
Direct characterization of beta-adrenoceptors in membranes of immature red blood cells from rats.
Topics: Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Count; Erythrocyte Membrane; Erythrocytes; Isoproterenol; Male; Pindolol; Practolol; Propranolol; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Reticulocytes; Temperature; Time Factors | 1978 |
[Comparative evaluation of new drugs used in the treatment of cardiac arrhythmia].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Ajmaline; Alprenolol; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Barbiturates; Drug Combinations; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Pindolol; Practolol; Propranolol; Sparteine; Verapamil | 1975 |
Beta-adrenergic blockade and atrio--ventricular conduction impairment.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atrioventricular Node; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Pindolol; Practolol; Propranolol; Refractory Period, Electrophysiological; Sotalol; Stereoisomerism | 1975 |
[Editorial: Importance of cardioselectivity and sympaticomimetric potential of beta-blockers (author's transl)].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Vessels; Ethanolamines; Heart; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Sympathomimetics | 1975 |
Effect of beta-adrenoceptor blocking drugs, physostigmine, and atropine on the toxicity of doxepin in mice.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atropine; Doxepin; Drug Interactions; Electrocardiography; Heart Rate; Male; Mice; Physostigmine; Practolol; Propanolamines; Propranolol | 1975 |
Analysis of the vasodilator action of alprenolol.
Topics: Alprenolol; Animals; Blood Pressure; Dogs; Female; Heart Rate; Male; Pindolol; Practolol; Procaine; Propranolol; Vasodilator Agents | 1978 |
[Proceedings: Effects of beta blockaders on left ventricular functions].
Topics: Alprenolol; Heart; Hemodynamics; Humans; Practolol | 1975 |
[Use of various beta-adrenergic blockers in clinical anesthesia. (5) Clinical and experimental use of practolol (Eraldin)].
Topics: Adult; Alprenolol; Anesthesia, Inhalation; Animals; Arrhythmias, Cardiac; Dogs; Enflurane; Halothane; Humans; Middle Aged; Oxprenolol; Pindolol; Practolol; Propranolol | 1975 |
Effect of chronic beta-adrenergic receptor blockade in congestive cardiomyopathy.
Topics: Adult; Alprenolol; Blood Pressure; Cardiac Output; Cardiac Volume; Diuretics; Female; Heart Failure; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Practolol; Radiography; Tachycardia | 1975 |
Letter: Long-term postinfarction treatment with practolol.
Topics: Alprenolol; Blood Pressure; Humans; Myocardial Infarction; Practolol | 1975 |
[The nature of differences in beta-adrenergic receptors].
Topics: Alprenolol; Animals; Carotid Arteries; Guinea Pigs; Heart; Isoproterenol; Muscle, Smooth; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Stomach; Trachea | 1975 |
Proceedings: Chronic beta-adrenergic receptor blockade in congestive cardiomyopathy.
Topics: Alprenolol; Heart Failure; Humans; Practolol | 1976 |
On the relationship between the inhibition of thrombin stimulated aggregation and thromboxane formation in isolated platelets treated with beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arachidonic Acid; Atenolol; Blood Platelets; Male; Membrane Fluidity; Metipranolol; Oxprenolol; Platelet Aggregation Inhibitors; Practolol; Propranolol; Rats; Rats, Wistar; Thrombin; Thromboxane A2 | 1992 |
Further evidence showing that the inhibitory action of serotonin on rat masculine sexual behavior is mediated after the stimulation of 5-HT1B receptors.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Animals; Ejaculation; Male; Piperazines; Practolol; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Sexual Behavior, Animal | 1992 |
Beta-adrenoceptors in human brain labelled with [3H]dihydroalprenolol and [3H]CGP 12177.
Topics: Adrenergic beta-Antagonists; Alprenolol; Binding, Competitive; Brain Chemistry; Dihydroalprenolol; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Kinetics; Male; Membranes; Middle Aged; Practolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1989 |
The beta 1- and beta 2-adrenoceptor stimulatory effects of alprenolol, oxprenolol and pindolol: a study in the isolated right atrium and uterus of the rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Female; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Oxprenolol; Pindolol; Practolol; Propanolamines; Rats; Rats, Inbred Strains; Uterus | 1986 |
Letter: Treatment of acute paracetamol poisoning.
Topics: Acetaminophen; Alprenolol; Animals; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Synergism; Mice; Poisoning; Practolol; Propranolol; Xylitol | 1973 |
Clinical aspects of the anti-arrhythmic actions of beta-receptor blocking drugs. 2. Clinical pharmacology.
Topics: Adrenergic beta-Antagonists; Alprenolol; Arrhythmias, Cardiac; Drug Therapy, Combination; Heart Failure; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Quinidine; Stereoisomerism; Structure-Activity Relationship | 1973 |
Further studies regarding the structure activity relationships of beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Aorta; Dogs; Heart; Isoproterenol; Methyl Ethers; Oxprenolol; Phenyl Ethers; Practolol; Propanolamines; Propranolol; Structure-Activity Relationship | 1973 |
Cardiac effects of beta-adrenergic receptor antagonists.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Cats; Dogs; Epinephrine; Heart; Heart Rate; Hemodynamics; Isoproterenol; Norepinephrine; Practolol; Propranolol | 1974 |
[Effects of various adrenergic beta receptor blockers on hypertensive reflexes induced by the stimulation of neural afferences].
Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia, General; Animals; Blood Pressure; Butoxamine; Dogs; Electric Stimulation; Gallamine Triethiodide; Pindolol; Practolol; Propranolol; Reflex | 1974 |
On the role of the adrenergic receptors for extraneuronal amine uptake and retention in rat salivary glands in vitro.
Topics: Adrenergic beta-Antagonists; Alprenolol; Amines; Animals; Dose-Response Relationship, Drug; Ethers; In Vitro Techniques; Isoproterenol; Male; Norepinephrine; Phenoxybenzamine; Practolol; Propanolamines; Propranolol; Propylamines; Rats; Receptors, Adrenergic; Salivary Glands; Sublingual Gland; Submandibular Gland; Time Factors; Toluene; Tritium | 1974 |
[Comparative effects of several beta-adrenergic inhibitors on pulmonary resistance in guinea pigs].
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure Determination; Bradycardia; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; Lung Compliance; Male; Plethysmography, Whole Body; Practolol; Propranolol; Stimulation, Chemical | 1973 |
Comparison of beta-adrenergic blocking activities of propranolol, isopropylmethoxamine, sotalol, practolol, alprenolol, pindolol, oxprenolol and D-32 in the atria and trachea of the guinea-pig.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Butylamines; Dose-Response Relationship, Drug; Electric Stimulation; Female; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Oxprenolol; Phenyl Ethers; Pindolol; Practolol; Propanolamines; Propranolol; Receptors, Drug; Sotalol; Trachea | 1974 |
GLC determination of propranolol, other beta-blocking drugs, and metabolites in biological fluids and tissues.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Body Fluids; Chromatography, Gas; Ethanolamines; Fluoroacetates; Humans; Isoproterenol; Mass Spectrometry; Myocardium; Oxprenolol; Practolol; Propranolol; Rats; Sotalol | 1974 |
[Beta-adrenergic inhibitors (pharmacologic data and deductions for therapeutic application)].
Topics: Adrenergic beta-Antagonists; Alprenolol; Biopharmaceutics; Heart; Humans; Oxygen Consumption; Pindolol; Practolol; Propranolol | 1973 |
[Indications for long term treatment of ventricular arrhythmias].
Topics: Alprenolol; Arrhythmias, Cardiac; Death, Sudden; Digitalis Glycosides; Electrocardiography; Humans; Long-Term Care; Phenytoin; Practolol; Procainamide; Quinidine | 1974 |
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors | 1974 |
[A beta blocking agent as an antihypertensive agent].
Topics: Aged; Alprenolol; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Pindolol; Practolol; Propranolol | 1973 |
The effect propranolol, alprenolol and practolol on the vibrinolytic and factor VIII responses to adrenaline and salbutamol in man.
Topics: Adult; Albuterol; Alprenolol; Epinephrine; Factor VIII; Fibrinolysis; Humans; Injections, Intravenous; Male; Plasminogen; Practolol; Propranolol; Pulse; Receptors, Adrenergic; Receptors, Drug | 1974 |
In vivo receptor binding of iodinated beta-adrenoceptor blockers.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Carbazoles; Dihydroalprenolol; Guinea Pigs; Iodine Radioisotopes; Levobunolol; Lung; Male; Myocardium; Practolol; Proadifen; Propanolamines; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1980 |
Penetration of five beta-adrenergic antagonists into the rabbit eye after ocular instillation.
Topics: Administration, Topical; Adrenergic beta-Agonists; Alprenolol; Animals; Aqueous Humor; Chromatography, Gas; Oxprenolol; Practolol; Propranolol; Rabbits; Timolol | 1981 |
Variability in the preventive action of the B-blockers on genetic hypertension in the rat.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors | 1980 |
[Beta blockage after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Humans; Myocardial Infarction; Practolol; Propranolol; Time Factors | 1982 |
A comparative study of the effects of metipranolol, propranolol, alprenolol, oxprenolol, pindolol and practolol on the circulation in experimental animals.
Topics: Alprenolol; Animals; Blood Circulation; Cats; Dogs; Female; Guinea Pigs; Heart Rate; Male; Metipranolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol | 1980 |
Some metabolic effects of metipranolol, propranolol, alprenolol, oxprenolol, and practolol in rats.
Topics: Alprenolol; Animals; Glycogen; Lactates; Lactic Acid; Male; Metipranolol; Oxprenolol; Practolol; Propanolamines; Propranolol; Rats; Rats, Inbred Strains | 1980 |
Absorption of beta-adrenoceptor antagonists to Amberlite resin.
Topics: Adrenergic alpha-Antagonists; Adsorption; Alprenolol; Hemoperfusion; Humans; In Vitro Techniques; Ion Exchange Resins; Metoprolol; Practolol; Prenalterol | 1983 |
Binding of [3H]-dihydroalprenolol and [3H]-acetobutolol to human blood platelets is not related to occupancy of beta-adrenoceptors.
Topics: Acebutolol; Alprenolol; Blood Platelets; Butoxamine; Dihydroalprenolol; Humans; Isoproterenol; Kinetics; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1983 |
Some characteristics of 3H-dihydroalprenolol binding to intact normal granulocytes, lymphocytes and membrane preparations of these cells.
Topics: Alprenolol; Cell Membrane; Dihydroalprenolol; Ethanolamines; Granulocytes; Humans; Lymphocytes; Practolol; Procaterol; Receptors, Adrenergic, beta; Tritium | 1984 |