alprenolol and metoprolol

alprenolol has been researched along with metoprolol in 99 studies

Research

Studies (99)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (48.48)	18.7374
1990's	13 (13.13)	18.2507
2000's	25 (25.25)	29.6817
2010's	13 (13.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H	1
Baldwin, JJ; Gross, DM; McClure, DE; Williams, M	1
Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Gubernator, K; Kansy, M; Senner, F	1
Artursson, P; Beigi, F; Lundahl, P; Luthman, K; Palm, K; Strandlund, G; Ungell, AL	1
Ghuloum, AM; Jain, AN; Sage, CR	1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S	1
Topliss, JG; Yoshida, F	1
Ertl, P; Rohde, B; Selzer, P	1
Faller, B; Wohnsland, F	1
Artursson, P; Luthman, K; Norinder, U; Stenberg, P	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Baker, JG	1
Artursson, P; Bergström, CA; Matsson, P; Nagahara, N; Norinder, U; Tavelin, S	1
Caron, G; Ermondi, G	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Akamatsu, M	1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Artursson, P; Mateus, A; Matsson, P	1
Levy, JV	1
Meier, J	1
Erdmann, E; Krawietz, W; Pruchniewski, M; Weinsteiger, M	1
Lund-Johansen, P	2
Kiechel, JR; Meier, J	1
Tannenbaum, H	1
Eliasson, K; Lins, LE; Sundqvist, K	1
Hoffmann, K	1
Malchoff, CD; Marinetti, GV	1
Tuomilehto, J	1
Ekelund, LG; Orö, L	1
Nissinen, A; Tuomilehto, J	1
Bottermann, P; Klein, G; Schinz, A; Schnelle, A; Zilker, T	1
Comerford, MB; Pringle, A	1
Rau, H	1
Enquist, M; Hermansson, J	1
Galbani, P; Pompeiano, M; Ronca-Testoni, S	1
Doggrell, SA	1
Fishbein, L; Jackson, CD	1
Brismar, K; Mogensen, L; Wetterberg, L	1
Baveja, SK; Dayer, P; Devi, KP; Leemann, T; Rao, KV	1
Boucher, M; Dubray, C; Duchene-Marullaz, P	1
Berglund, U; Dahlström, U; Karlsson, E	1
Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C	1
Borer, JS; Moses, JW	1
Bengtsson, C	3
Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP	1
Hjalmarson, A	1
Moss, AJ	1
Alvan, G; Calissendorff, BM; Haglund, K; Marén, N; Seideman, P	1
Gabrielsson, M; Heath, A; Redgårdh, CG	1
Christensen, LK; Hansen, JM; Perrild, H; Skovsted, L	1
Pratt, CM; Roberts, R	1
Ostman, J	1
Björkman, JA; Ek, L; Havu, N; Olovson, SG	1
Friedewald, WT; Frishman, WH; Furberg, CD	1
Tomov, I	1
Forsbeck, M; Olin, R; Stejskal, VD	1
Febvre, N; Lecaillon, JB; Souppart, C	1
Gal, J; Johnston, GD; Nies, AS	1
Holm, G; Johansson, S; Smith, U; Vedin, A; Wilhelmsson, C	1
Arner, P; Haglund, K; Juhlin-Dannfelt, A; Nowak, J; Ostman, J; Wennlund, A	1
Hermansson, J; von Bahr, C	1
Pettersson, C; Schill, G	1
Skånberg, I	1
Hesselgren, AM; Johansson, M; Salmonson, T; Sjöberg, P	1
Klug, S; Merker, HJ; Neubert, D; Schwabe, R; Thiel, R	1
Ijzerman, AP; Krasel, C; Lohse, MJ; Wieland, K; Zuurmond, HM	1
Ogawa, N	1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R	1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA	1
Vigh, G; Zhu, W	1
Aturki, Z; Cristalli, M; D'Orazio, G; Fanali, S; Quaglia, MG	1
Deadman, CM; Dickinson, PA; Kellaway, IW; Murdan, S; Yasin, M	1
D'Orazio, G; Fanali, S	1
Mizogami, M; Takakura, K; Tsuchiya, H	1

Reviews

10 review(s) available for alprenolol and metoprolol

Article	Year
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship	1988
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
[Long-term utilization of beta-blockers in arterial hypertension]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Tolerance; Heart Rate; Humans; Hypertension; Metoprolol; Pindolol; Practolol; Time Factors	1978
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
Beta-adrenergic antagonists in the treatment of patients with heart disease. Disease-a-month : DM, 1981, Volume: 27, Issue:9 Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol	1981
Beta blocking agents: current status in the prevention of sudden coronary death. Annals of the New York Academy of Sciences, 1982, Volume: 382 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol	1982
beta-adrenergic blockade and diabetes mellitus. A review. Acta medica Scandinavica. Supplementum, 1983, Volume: 672 Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Glucose; Catecholamines; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Drug Synergism; Fatty Acids, Nonesterified; Gluconeogenesis; Glucose Tolerance Test; Glycerol; Glycogen; Humans; Hypertension; Hypoglycemia; Insulin; Lactates; Lactic Acid; Metoprolol; Oxprenolol; Propranolol	1983
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984
[Analysis and characterization of ligand-receptor binding systems]. Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl 2 Topics: Alprenolol; Animals; Atropine; Binding, Competitive; Carbachol; Dihydroalprenolol; Humans; Ligands; Metoprolol; Receptors, Cell Surface; Receptors, Neurotransmitter	1997

Trials

15 trial(s) available for alprenolol and metoprolol

Article	Year
A comparison between metroprolol, alprenolol and oxprenolol in the treatment of hypertension. Acta medica Scandinavica. Supplementum, 1979, Volume: 625 Topics: Alprenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Follow-Up Studies; Humans; Hypertension; Metoprolol; Oxprenolol; Placebos; Propanolamines; Time Factors	1979
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study. Clinical cardiology, 1979, Volume: 2, Issue:3 Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Nifedipine; Placebos; Practolol; Pyridines	1979
Double-blind comparison of metoprolol, alprenolol, and oxprenolol in hypertension. European journal of clinical pharmacology, 1979, Volume: 16, Issue:6 Topics: Adult; Aged; Alprenolol; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Metoprolol; Middle Aged; Oxprenolol; Propanolamines	1979
Metoprolol in the long-term treatment of hypertension. The Practitioner, 1976, Volume: 217, Issue:1302 Topics: Adult; Aged; Alprenolol; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propanolamines; Time Factors	1976
Responses of the T-wave amplitude as a function of active and passive tasks and beta-adrenergic blockade. Psychophysiology, 1991, Volume: 28, Issue:2 Topics: Adaptation, Psychological; Adult; Alprenolol; Arousal; Double-Blind Method; Electrocardiography; Female; Heart; Humans; Male; Metoprolol; Middle Aged; Psychomotor Performance; Sympathetic Nervous System	1991
Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits. Acta medica Scandinavica, 1980, Volume: 207, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Heart Block; Heart Failure; Humans; Hypotension; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propranolol; Risk	1980
Duration of action of beta blockers. Clinical pharmacology and therapeutics, 1980, Volume: 27, Issue:5 Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol	1980
Seven years on a selective beta-blocker - metoprolol. A long-term study of women with arterial hypertension. Annals of clinical research, 1981, Volume: 13 Suppl 30 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Metoprolol; Middle Aged; Propanolamines	1981
Beta blocking agents: current status in the prevention of sudden coronary death. Annals of the New York Academy of Sciences, 1982, Volume: 382 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary Disease; Death, Sudden; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Practolol; Propranolol; Prospective Studies; Random Allocation; Timolol	1982
Postinfarction therapy with beta blockers: who should be treated? International journal of cardiology, 1982, Volume: 1, Issue:5-6 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Heart; Humans; Metoprolol; Myocardial Infarction; Propranolol; Random Allocation; Timolol	1982
Chronic beta blockade therapy in patients after myocardial infarction. The American journal of cardiology, 1983, Oct-01, Volume: 52, Issue:7 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Practolol; Propranolol; Timolol	1983
The use of beta-adrenergic blocking drugs in patients with myocardial infarction. Current problems in cardiology, 1984, Volume: 9, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans; Hypertension; Metoprolol; Myocardial Infarction; Oxprenolol; Pindolol; Practolol; Propranolol; Receptors, Adrenergic, beta; Risk; Sotalol; Timolol	1984
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct]. Vutreshni bolesti, 1984, Volume: 23, Issue:3 Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Placebos; Practolol; Propranolol; Random Allocation; Sotalol; Time Factors; Timolol	1984
The effect of beta-blockade on glucose tolerance and insulin release in adult diabetes. Acta medica Scandinavica, 1980, Volume: 208, Issue:3 Topics: Administration, Oral; Aged; Alprenolol; Blood Glucose; Diabetes Mellitus; Diet, Diabetic; Female; Glucose Tolerance Test; Humans; Injections, Intravenous; Insulin; Insulin Secretion; Male; Metoprolol; Middle Aged; Propanolamines	1980
Effect of metoprolol and alprenolol on the metabolic, hormonal, and haemodynamic response to insulin-induced hypoglycaemia in hypertensive, insulin-dependent diabetics. Acta medica Scandinavica, 1982, Volume: 211, Issue:5 Topics: Adult; Alprenolol; Diabetes Complications; Diabetes Mellitus; Female; Hemodynamics; Humans; Hypertension; Hypoglycemia; Insulin; Male; Metoprolol; Middle Aged; Propanolamines	1982

Other Studies

77 other study(ies) available for alprenolol and metoprolol

Article	Year
Use of (S)-(trifloxymethyl)oxirane in the synthesis of a chiral beta-adrenoceptor antagonist, (R)- and (S)-9-[[3-(tert-butylamino)-2-hydroxypropyl]oximino]fluorene. Journal of medicinal chemistry, 1982, Volume: 25, Issue:8 Topics: Adrenergic beta-Antagonists; Animals; Binding, Competitive; Chemical Phenomena; Chemistry; Dihydroalprenolol; Female; Guinea Pigs; Indicators and Reagents; Lung; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; Propanolamines; Stereoisomerism	1982
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations. Journal of medicinal chemistry, 1980, Volume: 23, Issue:5 Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors	1980
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7 Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet	1998
Evaluation of dynamic polar molecular surface area as predictor of drug absorption: comparison with other computational and experimental predictors. Journal of medicinal chemistry, 1998, Dec-31, Volume: 41, Issue:27 Topics: Adrenergic beta-Antagonists; Amides; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Drug Design; Epithelial Cells; Formamides; Humans; Intestinal Absorption; Liposomes; Models, Molecular; Molecular Conformation; Monte Carlo Method; Permeability; Propanolamines; Structure-Activity Relationship	1998
Molecular hashkeys: a novel method for molecular characterization and its application for predicting important pharmaceutical properties of molecules. Journal of medicinal chemistry, 1999, May-20, Volume: 42, Issue:10 Topics: Drug Design; Intestinal Absorption; Models, Molecular; Pharmaceutical Preparations; Structure-Activity Relationship	1999
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans. Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11 Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Fast calculation of molecular polar surface area as a sum of fragment-based contributions and its application to the prediction of drug transport properties. Journal of medicinal chemistry, 2000, Oct-05, Volume: 43, Issue:20 Topics: Biological Availability; Biological Transport; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Reproducibility of Results	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Experimental and computational screening models for the prediction of intestinal drug absorption. Journal of medicinal chemistry, 2001, Jun-07, Volume: 44, Issue:12 Topics: Biological Transport; Carbon Radioisotopes; Cell Line; Cell Membrane; Cell Membrane Permeability; Ciprofloxacin; Computational Biology; Drug Design; Foscarnet; Humans; Hydrogen Bonding; Intestinal Absorption; Intestinal Mucosa; Lactulose; Mannitol; Models, Biological; Raffinose; Surface Properties; Tritium; Verapamil	2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Exploring the role of different drug transport routes in permeability screening. Journal of medicinal chemistry, 2005, Jan-27, Volume: 48, Issue:2 Topics: Administration, Oral; Biological Transport; Caco-2 Cells; Cell Line; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Membranes, Artificial; Models, Biological; Molecular Conformation; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Pharmacokinetics	2005
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists. Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3 Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20 Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2 Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Beta-adrenergic receptor blocking drugs in spontaneous hypertension. The American journal of medicine, 1976, Volume: 61, Issue:5 Topics: Adrenergic beta-Antagonists; Aging; Alprenolol; Animals; Blood Pressure; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Pulse; Rats; Rats, Inbred Strains; Sodium Chloride; Sotalol; Stereoisomerism; Time Factors	1976
Pindolol: a pharmacokinetic comparison with other beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1977, Volume: 606 Topics: Adrenergic beta-Antagonists; Alprenolol; Biological Availability; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Protein Binding; Sotalol; Timolol	1977
[Properties of beta-adrenergic receptors of heart and lung--studies with "cardioselective" beta-receptor blocking substances]. Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43 Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Binding, Competitive; Heart; Lung; Metoprolol; Oxprenolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta	1977
alpha-Methyldopa and beta-blockers in hypertension--a comparison of their haemodynamic effects. Clinical and experimental pharmacology & physiology. Supplement, 1978, Volume: 4 Topics: Adrenergic beta-Antagonists; Alprenolol; Hemodynamics; Humans; Hypertension; Methyldopa; Metoprolol; Physical Exertion; Propranolol; Time Factors; Timolol	1978
Vasospastic phenomena in patients treated with beta-adrenoceptor blocking agents. Acta medica Scandinavica. Supplementum, 1979, Volume: 628 Topics: Adrenergic beta-Antagonists; Alprenolol; Blood Circulation; Cardiac Output; Female; Humans; Hypertension; Male; Metoprolol; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature; Timolol	1979
Studies on the metabolism of the beta-adrenoceptor antagonists alprenolol, metoprolol and pamatolol. Acta pharmaceutica Suecica, 1979, Volume: 16, Issue:2 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anura; Carbamates; Humans; Metoprolol; Propanolamines; Rats	1979
Hormone action at the membrane level. VI. Binding of (-)-[3H]dihydroalprenolol and (+/-)-[3H]isoproterenol to turkey erythrocytes and correlation with adenylate cyclase activity. Biochimica et biophysica acta, 1978, Feb-01, Volume: 538, Issue:3 Topics: Adenylyl Cyclases; Alprenolol; Animals; Binding Sites; Epinephrine; Erythrocyte Membrane; Erythrocytes; Ethanolamines; Female; Isoproterenol; Metoprolol; Norepinephrine; Practolol; Propranolol; Receptors, Adrenergic, beta; Stereoisomerism; Turkeys	1978
[Effects of metoprolol and alprenolol on the carbohydrate and lipid metabolism during beta adrenergic stimulation with isoproterenol in the normal subject]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Alprenolol; Carbohydrate Metabolism; Humans; Isoproterenol; Lipid Metabolism; Metoprolol; Propanolamines; Stimulation, Chemical	1978
Separation of the enantiomers of beta-receptor blocking agents and other cationic drugs using a CHIRAL-AGP column. Binding properties and characterization of immobilized alpha 1-acid glycoprotein. Journal of chromatography, 1990, Nov-02, Volume: 519, Issue:2 Topics: Adrenergic beta-Antagonists; Adsorption; Alprenolol; Atenolol; Binding Sites; Butylamines; Chromatography; Metoprolol; Molecular Structure; Orosomucoid; Oxprenolol; Pindolol; Propranolol; Protein Conformation; Spectrometry, Fluorescence; Stereoisomerism	1990
Distribution of beta-adrenergic receptors in different cortical and nuclear regions of cat cerebellum, as revealed by binding studies. Archives italiennes de biologie, 1989, Volume: 127, Issue:2 Topics: Alprenolol; Animals; Binding, Competitive; Cats; Cerebellar Nuclei; Cerebral Cortex; Dihydroalprenolol; Metoprolol; Receptors, Adrenergic, beta	1989
The effects of beta-adrenoreceptor antagonists on the force responses of the electrically driven rat right ventricle strip to isoprenaline. Journal of autonomic pharmacology, 1989, Volume: 9, Issue:4 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Male; Metoprolol; Myocardial Contraction; Pindolol; Propanolamines; Rats; Rats, Inbred Strains	1989
Depressed melatonin secretion in patients with nightmares due to beta-adrenoceptor blocking drugs. Acta medica Scandinavica, 1987, Volume: 221, Issue:2 Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Atenolol; Dreams; Female; Hallucinations; Humans; Male; Melatonin; Metoprolol; Middle Aged; Propranolol	1987
Determination of alprenolol and metoprolol in plasma by column liquid chromatography. Journal of chromatography, 1988, Dec-29, Volume: 434, Issue:1 Topics: Alprenolol; Animals; Chromatography, Liquid; Dogs; Metoprolol; Spectrometry, Fluorescence	1988
Pharmacological evidence for differences in the beta-adrenoreceptor populations mediating atrial and ventricular chronotropic responses in the unanaesthetized dog. Journal of autonomic pharmacology, 1984, Volume: 4, Issue:4 Topics: Alprenolol; Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male; Metoprolol; Parasympatholytics; Propranolol; Receptors, Adrenergic, beta	1984
Variability in the preventive action of the B-blockers on genetic hypertension in the rat. Paroi arterielle, 1980, Volume: 6, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors	1980
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade. Acta ophthalmologica, 1982, Volume: 60, Issue:1 Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol	1982
Absorption of beta-adrenoceptor antagonists to Amberlite resin. British journal of clinical pharmacology, 1983, Volume: 15, Issue:4 Topics: Adrenergic alpha-Antagonists; Adsorption; Alprenolol; Hemoperfusion; Humans; In Vitro Techniques; Ion Exchange Resins; Metoprolol; Practolol; Prenalterol	1983
Different effects of propranolol, alprenolol, sotalol, atenolol and metoprolol on serum T3 and serum rT3 in hyperthyroidism. Clinical endocrinology, 1983, Volume: 18, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Humans; Hyperthyroidism; Metoprolol; Middle Aged; Propranolol; Sotalol; Triiodothyronine; Triiodothyronine, Reverse	1983
Central haemodynamic effects of beta blockers in hypertension. A comparison between atenolol, metoprolol, timolol, penbutolol, alprenolol pindolol and bunitrolol. European heart journal, 1983, Volume: 4 Suppl D Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Hemodynamics; Humans; Hypertension; Metoprolol; Pindolol; Propanolamines; Time Factors; Timolol	1983
The ulcerogenic effect on the oesophagus of three beta-adrenoceptor antagonists, investigated in a new porcine oesophagus test model. Acta pharmacologica et toxicologica, 1983, Volume: 53, Issue:5 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Esophageal Diseases; Esophagus; Female; Male; Metoprolol; Propranolol; Swine; Ulcer	1983
Impairment of physical performance after treatment with beta blockers and alpha blockers. British medical journal (Clinical research ed.), 1984, Mar-03, Volume: 288, Issue:6418 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running	1984
Diagnosis of drug-induced occupational allergy by lymphocyte transformation test. Developments in toxicology and environmental science, 1983, Volume: 11 Topics: Alprenolol; Ampicillin; Chlormethiazole; Dermatitis, Occupational; Drug Hypersensitivity; Humans; Lymphocyte Activation; Metoprolol; Occupational Diseases; Quinidine	1983
Influence of solute polarity in column-switching chromatography for the assay of drugs in plasma and urine. Journal of chromatography, 1984, Dec-28, Volume: 317 Topics: Acetonitriles; Alprenolol; Chromatography; Humans; Metoprolol; Pharmaceutical Preparations; Pyrrolidines	1984
Determination of metoprolol in human blood plasma using high-performance liquid chromatography. Journal of chromatography, 1983, Nov-11, Volume: 278, Issue:1 Topics: Alprenolol; Chromatography, High Pressure Liquid; Humans; Metoprolol	1983
Determination of (R)-AND (S)-alprenolol-and (R)- and (S)-metoprolol as their diastereomeric derivatives in human plasma by reversed-phase liquid chromatography. Journal of chromatography, 1982, Jan-08, Volume: 227, Issue:1 Topics: Alprenolol; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Kinetics; Metoprolol; Propanolamines; Reference Values; Stereoisomerism; Time Factors	1982
Separation of enantiomeric amines by ion-pair chromatography. Journal of chromatography, 1981, Jan-16, Volume: 204 Topics: Alprenolol; Chromatography, High Pressure Liquid; Metoprolol; Propanolamines; Propranolol	1981
Metabolism of two beta-adrenoceptor antagonists, alprenolol and metoprolol, in different species. In-vitro and in-vivo correlations. Acta pharmaceutica Suecica, 1980, Volume: 17, Issue:5 Topics: Alprenolol; Animals; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Metoprolol; Mice; Microsomes, Liver; Propanolamines; Rats; Species Specificity	1980
Enantioselective assay of beta-receptor antagonists present in microdialysis and plasma samples of rats. Chirality, 1995, Volume: 7, Issue:4 Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Brain; Chromatography, High Pressure Liquid; Metoprolol; Microdialysis; Propranolol; Rats; Spectrometry, Fluorescence; Stereoisomerism	1995
Toxicity of beta-blockers in a rat whole embryo culture: concentration-response relationships and tissue concentrations. Archives of toxicology, 1994, Volume: 68, Issue:6 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; In Vitro Techniques; Metoprolol; Pindolol; Propranolol; Rats; Rats, Wistar	1994
Involvement of Asn-293 in stereospecific agonist recognition and in activation of the beta 2-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17 Topics: Adenylyl Cyclases; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Alprenolol; Animals; Asparagine; Binding Sites; CHO Cells; Computer Simulation; Cricetinae; Humans; Isoproterenol; Metoprolol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Propranolol; Receptors, Adrenergic, beta-2; Serine; Signal Transduction; Stereoisomerism	1996
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions. Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2 Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol	1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol	1998
One doctor's 25-year experience of beta-blocker treatment to the same group of hypertensive women. Scandinavian journal of primary health care, 1999, Volume: 17, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Antihypertensive Agents; Body Weight; Continuity of Patient Care; Female; Follow-Up Studies; Humans; Hypertension; Metoprolol; Physician-Patient Relations; Prospective Studies; Sweden	1999
Experimental verification of a predicted, hitherto unseen separation selectivity pattern in the nonaqueous capillary electrophoretic separation of weak base enantiomers by octakis (2,3-diacetyl-6-sulfato)-gamma-cyclodextrin. Electrophoresis, 2000, Volume: 21, Issue:10 Topics: Albuterol; Alprenolol; Cyclodextrins; Electrophoresis, Capillary; gamma-Cyclodextrins; Indicators and Reagents; Kinetics; Methadone; Metoprolol; Models, Theoretical; Stereoisomerism	2000
Use of vancomycin chiral stationary phase for the enantiomeric resolution of basic and acidic compounds by nano-liquid chromatography. Journal of chromatography. A, 2005, Jul-15, Volume: 1081, Issue:1 Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Chromatography, Liquid; Metoprolol; Nanotechnology; Pharmaceutical Preparations; Pindolol; Stereoisomerism; Vancomycin	2005
An investigation into the influence of drug lipophilicity on the in vivo absorption profiles from subcutaneous microspheres and in situ forming depots. Journal of controlled release : official journal of the Controlled Release Society, 2007, Sep-11, Volume: 122, Issue:1 Topics: Adsorption; Alprenolol; Animals; Delayed-Action Preparations; Drug Carriers; Drug Implants; Hydrophobic and Hydrophilic Interactions; Injections, Subcutaneous; Lactic Acid; Metoprolol; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats	2007
Enantiomeric separation by using nano-liquid chromatography with on-column focusing. Journal of separation science, 2008, Volume: 31, Issue:14 Topics: Adrenergic beta-Antagonists; Alprenolol; Calibration; Chromatography, Liquid; Metoprolol; Nanotechnology; Oxprenolol; Particle Size; Propranolol; Reproducibility of Results; Silicon Dioxide; Stereoisomerism; Time Factors; Vancomycin	2008
The interactivities with lipid membranes differentially characterize selective and nonselective beta1-blockers. European journal of anaesthesiology, 2010, Volume: 27, Issue:9 Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia; Anesthetics; Atenolol; Biomimetics; Lipid Bilayers; Lipids; Liposomes; Membranes, Artificial; Metoprolol; Oxprenolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta	2010