alprenolol and cocaine

alprenolol has been researched along with cocaine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's2 (18.18)18.2507
2000's6 (54.55)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Bellman, K; Knegtel, RM; Settimo, L1
Darmani, NA; Glennon, RA; Martin, BR; Pandey, U1
Endoh, M; Hashimoto, K; Kimura, T1
Darmani, NA1
Huang, B; Li, HH; Li, YX; Liu, X; Ma, L; Tao, YZ1

Other Studies

11 other study(ies) available for alprenolol and cocaine

ArticleYear
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Inhibition of 5-HT2 receptor-mediated head-twitch response by cocaine via indirect stimulation of adrenergic alpha 2 and serotonergic 5-HT1A receptors.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: Adrenergic alpha-Agonists; Alprenolol; Amphetamines; Animals; Brain Chemistry; Cocaine; Dose-Response Relationship, Drug; Indoles; Male; Mice; Mice, Inbred ICR; Norepinephrine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tropisetron; Yohimbine

1991
Effects of perivascular nerve stimulation on the contraction and automaticity of the blood-perfused canine papillary muscle.
    British journal of pharmacology, 1972, Volume: 45, Issue:4

    Topics: Alprenolol; Animals; Atropine; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Perfusion; Pindolol; Propranolol; Reserpine; Tetrodotoxin

1972
Role of the inhibitory adrenergic alpha 2 and serotonergic 5-HT1A components of cocaine's actions on the DOI-induced head-twitch response in 5-HT2-receptor supersensitive mice.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:2

    Topics: Alprenolol; Amphetamines; Animals; Anxiety; Behavior, Animal; Cocaine; Drug Resistance; Male; Mice; Mice, Inbred ICR; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Receptor Agonists; Yohimbine

1993
β-Arrestin-biased signaling mediates memory reconsolidation.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Apr-07, Volume: 112, Issue:14

    Topics: Alprenolol; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Brain; Brain Mapping; Carbazoles; Carvedilol; Cocaine; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Signal Transduction; Time Factors

2015