alprenolol and carvedilol

alprenolol has been researched along with carvedilol in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's9 (50.00)29.6817
2010's8 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Topliss, JG; Yoshida, F1
Baker, JG1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Gozalbes, R; Pineda-Lucena, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Bond, RA; Callaerts-Vegh, Z; Evans, KL; Liu, X1
Bond, RA; Callaerts-Vegh, Z; Cuba, DL; Davies, PJ; Evans, KL; Giles, H; Gurji, HA; Shipley, GL1
Chen, J; Kim, IM; Rockman, HA; Salazar, NC; Tilley, DG; Violin, JD; Whalen, EJ1
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA1
Huang, B; Li, HH; Li, YX; Liu, X; Ma, L; Tao, YZ1
Bond, RA; Bouvier, M; Forkuo, GS; Joshi, R; Knoll, BJ; Leff, P; Parra, S; Thanawala, VJ; Valdez, DJ1
Andresen, BT; Chang, A; Chen, S; Cleveland, KH; Guo, L; Huang, KM; Huang, Y; Liang, S1

Other Studies

18 other study(ies) available for alprenolol and carvedilol

ArticleYear
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Chronic infusion of beta-adrenoceptor antagonist and inverse agonists decreases elevated protein kinase A activity in transgenic mice with cardiac-specific overexpression of human beta 2-adrenoceptor.
    Journal of cardiovascular pharmacology, 2002, Volume: 40, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Carbazoles; Carvedilol; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Heart Atria; Heart Ventricles; Humans; Infusion Pumps, Implantable; Mice; Mice, Transgenic; Myocardium; Propanolamines; Receptors, Adrenergic, beta-2

2002
Effects of different beta adrenoceptor ligands in mice with permanent occlusion of the left anterior descending coronary artery.
    British journal of pharmacology, 2003, Volume: 138, Issue:8

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Carbazoles; Carvedilol; Coronary Disease; Coronary Vessels; Ligands; Male; Mice; Mice, Inbred C57BL; Propanolamines; Receptors, Adrenergic, beta

2003
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.
    Proceedings of the National Academy of Sciences of the United States of America, 2008, Sep-23, Volume: 105, Issue:38

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Arrestins; beta-Arrestins; Carbazoles; Carvedilol; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Activation; Enzymes; ErbB Receptors; Erlotinib Hydrochloride; Genes, erbB-1; Heart; Humans; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Propanolamines; Quinazolines; Signal Transduction; Transcriptional Activation

2008
1H and 13C NMR characteristics of β-blockers.
    Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:5

    Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol

2011
β-Arrestin-biased signaling mediates memory reconsolidation.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Apr-07, Volume: 112, Issue:14

    Topics: Alprenolol; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Brain; Brain Mapping; Carbazoles; Carvedilol; Cocaine; Cyclic AMP-Dependent Protein Kinases; Extracellular Signal-Regulated MAP Kinases; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Signal Transduction; Time Factors

2015
β-Blockers have differential effects on the murine asthma phenotype.
    British journal of pharmacology, 2015, Volume: 172, Issue:20

    Topics: Adrenergic beta-Antagonists; Allergens; Alprenolol; Animals; Asthma; Bronchoalveolar Lavage Fluid; Carbazoles; Carvedilol; Cell Count; Epinephrine; Female; Male; Mice, Knockout; Models, Biological; Mucins; Nadolol; Ovalbumin; Phenotype; Propanolamines; Propranolol

2015
Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Carvedilol; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Growth Factor; Inhibitory Concentration 50; Labetalol; Ligands; Mice; Mice, Inbred C57BL; Receptors, Adrenergic; Receptors, Adrenergic, beta; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Ultraviolet Rays

2019