alprenolol and atropine

alprenolol has been researched along with atropine in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199021 (50.00)18.7374
1990's8 (19.05)18.2507
2000's8 (19.05)29.6817
2010's5 (11.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Bard, B; Carrupt, PA; Martel, S1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Hib, J1
Pöntinen, PJ2
Elonen, E1
Chiba, S2
Chiba, S; Imai, Y1
Firestein, S; Shepherd, GM1
Fekete, Z; Murty, VL; Sengupta, S; Slomiany, A; Slomiany, BL1
Piotrowski, E; Sengupta, S; Slomiany, A; Slomiany, BL2
de Borda, LS; Gimeno, AL; Gimeno, MF1
Hashimoto, K; Kubota, K1
Hayman, DG; Ireson, JD; Leslie, GB; Smith, S1
Day, MD; Roach, AG1
Polidoro, J; Seeber, AM; Taquini, AC1
Combre, A; Delort, P; Duchène-Marullaz, P; Lapalus, P1
Holmberg, S; Husaini, MH; Kvasnicka, J; Ryèn, L1
Bassett, AL; Danilo, P; Gelband, H; Nilsson, K; Wiggins, JR1
Folkow, B; Hallbäck, M1
Endoh, M; Hashimoto, K; Kimura, T1
Battersby, LA; Cruickshank, JM; Prichard, BN1
Brown, LA; Longmore, WJ1
Cosentino, M; Costa, A; Crema, A; D'Angelo, L; De Ponti, F; Frigo, G; Gibelli, G; Girani, M1
Fukada, Y; Haga, K; Haga, T; Kameyama, K; Katada, T; Kontani, K1
Baranowska, B; Kawalec, M; Krawczyk, E; Płlonowski, A; Radzikowska, M; Roguski, K; Wasilewska-Dziubińska, E1
Ogawa, N1

Reviews

2 review(s) available for alprenolol and atropine

ArticleYear
Overdosage with beta-adrenergic blocking agents.
    Adverse drug reactions and acute poisoning reviews, 1984,Summer, Volume: 3, Issue:2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alprenolol; Atropine; Blood Glucose; Cardiovascular System; Central Nervous System; Drug Tolerance; Heart Rate; Humans; Kinetics; Oxprenolol; Pindolol; Propranolol; Respiration; Sotalol

1984
[Analysis and characterization of ligand-receptor binding systems].
    Nihon rinsho. Japanese journal of clinical medicine, 1997, Volume: 55 Suppl 2

    Topics: Alprenolol; Animals; Atropine; Binding, Competitive; Carbachol; Dihydroalprenolol; Humans; Ligands; Metoprolol; Receptors, Cell Surface; Receptors, Neurotransmitter

1997

Other Studies

40 other study(ies) available for alprenolol and atropine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:5

    Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors

1980
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
    Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10

    Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Effects of autonomic drugs on epididymal contractions.
    Fertility and sterility, 1976, Volume: 27, Issue:8

    Topics: Acetylcholine; Alprenolol; Animals; Atropine; Epididymis; Epinephrine; Male; Metaproterenol; Muscle, Smooth; Neurotransmitter Agents; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Sympatholytics

1976
Cardiovascular effects of local adrenaline infiltration during halothane anaesthesia and adrenergic beta-receptor blockade in man.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Alprenolol; Anesthesia, General; Arrhythmias, Cardiac; Atropine; Blood Pressure; Child; Epinephrine; Female; Halothane; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Practolol; Propranolol

1978
Cardiovascular effects of local adrenaline infiltration during neurolept analgesia and adrenergic beta-receptor blockade in man.
    Acta anaesthesiologica Scandinavica, 1978, Volume: 22, Issue:2

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Arrhythmias, Cardiac; Atropine; Blood Pressure; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Neuroleptanalgesia; Propranolol

1978
Effect of beta-adrenoceptor blocking drugs, physostigmine, and atropine on the toxicity of doxepin in mice.
    Medical biology, 1975, Volume: 53, Issue:4

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Atropine; Doxepin; Drug Interactions; Electrocardiography; Heart Rate; Male; Mice; Physostigmine; Practolol; Propanolamines; Propranolol

1975
Mechanism of chronotropic and inotropic effects of phenylephrine.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:4

    Topics: Alprenolol; Animals; Atropine; Depression, Chemical; Desipramine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Rate; Heart Ventricles; In Vitro Techniques; Injections, Intra-Arterial; Levobunolol; Methoxamine; Myocardial Contraction; Phentolamine; Phenylephrine; Stimulation, Chemical; Tetrodotoxin

1977
Positive chronotropic and negative inotropic actions of vasopressin in isolated blood-perfused canine atrium.
    Japanese heart journal, 1977, Volume: 18, Issue:2

    Topics: Acetylcholine; Alprenolol; Animals; Atrial Function; Atropine; Blood; Dogs; Dose-Response Relationship, Drug; Heart Atria; Heart Rate; Myocardial Contraction; Norepinephrine; Sinoatrial Node; Vasopressins

1977
Pharmacologic analysis of papaverine-induced positive chronotropic and inotropic effects.
    European journal of pharmacology, 1976, Volume: 35, Issue:1

    Topics: Alprenolol; Animals; Atropine; Desipramine; Heart; Heart Rate; In Vitro Techniques; Manganese; Myocardial Contraction; Norepinephrine; Papaverine; Stimulation, Chemical; Tetrodotoxin; Tyramine

1976
Neurotransmitter antagonists block some odor responses in olfactory receptor neurons.
    Neuroreport, 1992, Volume: 3, Issue:8

    Topics: 2-Amino-5-phosphonovalerate; Alprenolol; Ambystoma; Animals; Atropine; Cyclic GMP; Electric Stimulation; Epithelium; In Vitro Techniques; Neurons; Neurotransmitter Agents; Nose; Odorants; Propranolol; Receptors, Neurotransmitter; Sensory Receptor Cells

1992
Adrenergic and cholinergic regulation of phospholipid release in sublingual salivary gland in vitro.
    General pharmacology, 1991, Volume: 22, Issue:5

    Topics: Alprenolol; Animals; Atropine; Choline; In Vitro Techniques; Isoproterenol; Male; Parasympathetic Nervous System; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Salivary Glands; Sympathetic Nervous System

1991
Adrenergic and cholinergic regulation of gastric mucus phospholipid secretion.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:1

    Topics: Alprenolol; Animals; Atropine; Autonomic Agents; Cells, Cultured; Gastric Mucosa; Isoproterenol; Male; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains; Time Factors

1992
Role of adrenergic and cholinergic mediators in gastric mucus phospholipid secretion.
    Biochemistry international, 1991, Volume: 24, Issue:6

    Topics: Alprenolol; Animals; Atropine; Autonomic Agents; Choline; Gastric Mucosa; Isoproterenol; Lysophosphatidylcholines; Male; Phospholipids; Pilocarpine; Rats; Rats, Inbred Strains

1991
Frequency-force relationship on isolated rat and guinea pig atria. Effects of cholinergic and adrenergic receptor antagonists.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 145, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Atropine; Electric Stimulation; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Parasympatholytics; Phentolamine; Rats; Stimulation, Chemical

1974
Positive chronotropic effect of ouabain in the excised and blood-perfused canine SA node preparation of the dog.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 281, Issue:4

    Topics: Acetylcholine; Alprenolol; Animals; Atropine; Calcium; Dogs; Electrocardiography; Electrodes; Glucagon; Heart Arrest; Heart Rate; Manganese; Norepinephrine; Ouabain; Perfusion; Propranolol; Reserpine; Sinoatrial Node; Stimulation, Chemical; Tetrodotoxin; Tyramine

1974
The effects of some beta adrenergic blocking agents on the central and peripheral actions of tremorine and oxotremorine.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Atropine; Central Nervous System; Drug Antagonism; Ethanolamines; Hypothermia; Male; Mice; Oxotremorine; Parasympathomimetics; Propranolol; Sympatholytics; Tremor; Tremorine

1972
Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.
    British journal of pharmacology, 1974, Volume: 51, Issue:3

    Topics: Albuterol; Alprenolol; Animals; Atropine; Bethanidine; Blood Pressure; Cats; Cerebral Ventricles; Clonidine; Dopamine; Epinephrine; Female; Heart Rate; Hexamethonium Compounds; Injections; Isoproterenol; Lidocaine; Male; Norepinephrine; Pempidine; Phentolamine; Practolol; Propranolol; Rabbits; Rats; Receptors, Adrenergic; Sotalol; Species Specificity; Time Factors

1974
Cardiac pressoreceptors in rat.
    Experientia, 1972, Nov-15, Volume: 28, Issue:11

    Topics: Alprenolol; Animals; Aorta; Atropine; Heart; Heart Rate; Heart Ventricles; Medulla Oblongata; Neural Pathways; Pressoreceptors; Rats; Vagotomy; Vagus Nerve

1972
[Nycthemeral variation in the cardiac frequency of dogs with chronic auriculo-ventricular dissociation. Role of extrinsic cardiac innervation].
    Journal de physiologie, 1972, Volume: 65

    Topics: Alprenolol; Animals; Atropine; Dogs; Heart Conduction System; Heart Rate; Periodicity; Pindolol; Propranolol

1972
Action of verapamil on sinus node, atrioventricular, and intraventricular conduction.
    British heart journal, 1973, Volume: 35, Issue:7

    Topics: Adult; Aged; Alprenolol; Arrhythmias, Cardiac; Atropine; Electrocardiography; Heart Block; Heart Conduction System; Humans; Middle Aged; Pacemaker, Artificial; Sinoatrial Node; Verapamil

1973
Direct and indirect inotropic effects of nicotine on cat ventricular muscle.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:1

    Topics: Alprenolol; Animals; Atropine; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Electric Stimulation; Epinephrine; Heart Rate; Heart Ventricles; Hexamethonium Compounds; Nicotine; Papillary Muscles; Propranolol; Reserpine; Stimulation, Chemical; Time Factors; Tyramine

1974
Cardiovascular responses to acute mental 'stress' in spontaneously hypertensive rats.
    Acta physiologica Scandinavica, 1974, Volume: 90, Issue:4

    Topics: Alprenolol; Animals; Atropine; Blood Pressure; Depression, Chemical; Epinephrine; Female; Heart Rate; Humans; Hypertension; Light; Male; Noise; Rats; Stimulation, Chemical; Stress, Psychological; Vibration

1974
Effects of perivascular nerve stimulation on the contraction and automaticity of the blood-perfused canine papillary muscle.
    British journal of pharmacology, 1972, Volume: 45, Issue:4

    Topics: Alprenolol; Animals; Atropine; Cocaine; Dogs; Electric Stimulation; Female; Guanethidine; Hexamethonium Compounds; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Papillary Muscles; Perfusion; Pindolol; Propranolol; Reserpine; Tetrodotoxin

1972
Adrenergic and cholinergic regulation of lung surfactant secretion in the isolated perfused rat lung and in the alveolar type II cell in culture.
    The Journal of biological chemistry, 1981, Jan-10, Volume: 256, Issue:1

    Topics: Acetylcholine; Alprenolol; Animals; Atropine; Cells, Cultured; Cyclic AMP; Cyclic GMP; In Vitro Techniques; Isoproterenol; Kinetics; Lung; Male; Perfusion; Phentolamine; Phenylephrine; Pulmonary Alveoli; Pulmonary Surfactants; Rats

1981
Inhibitory effects of SR 58611A on canine colonic motility: evidence for a role of beta 3-adrenoceptors.
    British journal of pharmacology, 1995, Volume: 114, Issue:7

    Topics: Adrenergic beta-Agonists; Alprenolol; Animals; Atropine; Colon; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Heart Rate; Isoproterenol; Receptors, Adrenergic, beta; Ritodrine; Tetrahydronaphthalenes

1995
Activation by G protein beta gamma subunits of beta-adrenergic and muscarinic receptor kinase.
    The Journal of biological chemistry, 1993, Apr-15, Volume: 268, Issue:11

    Topics: Alprenolol; Animals; Atropine; Base Sequence; beta-Adrenergic Receptor Kinases; Carbachol; Cattle; Cell Line; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; G-Protein-Coupled Receptor Kinase 2; Genetic Vectors; GTP-Binding Proteins; Humans; Isoproterenol; Kinetics; Lung; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphorylation; Protein Kinases; Receptor Protein-Tyrosine Kinases; Receptors, Muscarinic; Recombinant Proteins; Rhodopsin; Transfection

1993
Effects of PACAP and VIP on adrenal progesterone release.
    Annals of the New York Academy of Sciences, 1996, Dec-26, Volume: 805

    Topics: Adrenal Glands; Alprenolol; Animals; Atropine; Cells, Cultured; Culture Media, Serum-Free; Female; Granulosa Cells; Hexamethonium; Hysterectomy; Naltrexone; Neuropeptides; Neurotransmitter Agents; Ovariectomy; Pituitary Adenylate Cyclase-Activating Polypeptide; Progesterone; Rats; Rats, Inbred WKY; Vasoactive Intestinal Peptide

1996