alprenolol and acebutolol

alprenolol has been researched along with acebutolol in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (31.11)	18.7374
1990's	8 (17.78)	18.2507
2000's	14 (31.11)	29.6817
2010's	9 (20.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carrupt, PA; el Tayar, N; Testa, B; Van de Waterbeemd, H	1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Baker, JG	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Carrupt, PA; Guillarme, D; Henchoz, Y; Rudaz, S; Veuthey, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahman, M; Holmén, AG; Wan, H	1
Bard, B; Carrupt, PA; Martel, S	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Gozalbes, R; Pineda-Lucena, A	1
Akamatsu, M	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Bellman, K; Knegtel, RM; Settimo, L	1
Pfeifer, S; Zimmer, C	1
Miesch, F; Schwartz, J; Spach, MO	1
Aubert, Ph; Chaignon, M; Guédon, J; Lucsko, M	1
Kiechel, JR; Meier, J	1
Tannenbaum, H	1
Dubach, UC	1
Fishbein, L; Jackson, CD	1
Drayer, JI; Weber, MA	1
Borer, JS; Moses, JW	1
Brotelle, R; Colot, M; de Clavière, M; Heyndrickx, JP	1
Pong, SF; Tinkham, CL	1
Haber, E; Homcy, CJ; Rockson, SG	1
Kerry, R; Scrutton, MC	1
Gobburu, JV; Shelver, WH	1
Brøndsted, H; Bundgaard, H; Buur, A; Hovgaard, L	1
Klug, S; Merker, HJ; Neubert, D; Schwabe, R; Thiel, R	1
Arnhold, J; Arnold, K; Seifert, T; Zschörnig, O	1
Gemba, M; Hosaka, K; Kamiyama, M; Kobayashi, I; Konno, C; Maruo, H; Ueno, T	1
Caldwell, GW; Evangelisto, M; Masucci, JA; White, R	1
Caldwell, GW; Demarest, K; Easlick, SM; Gunnet, J; Masucci, JA	1
Pisklak, DM; Wawer, I; Zielińska-Pisklak, MA	1
Boujtita, M; Bussy, U; Delaforge, M; El-Bekkali, C; Ferchaud-Roucher, V; Galland, N; Jacquemin, D; Krempf, M; Tea, I	1

Reviews

6 review(s) available for alprenolol and acebutolol

Article	Year
Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists. Journal of medicinal chemistry, 1988, Volume: 31, Issue:11 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Models, Molecular; Receptors, Adrenergic, beta; Structure-Activity Relationship	1988
[Biotransformation and pharmacokinetics of beta-receptor blockaders]. Die Pharmazie, 1975, Volume: 30, Issue:10 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Biotransformation; Ethanolamines; Humans; Isoproterenol; Kinetics; Levobunolol; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Sotalol	1975
[Comparative pharmacokinetics of beta-blockers]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Half-Life; Humans; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Timolol	1978
[Long-term utilization of beta-blockers in arterial hypertension]. La Nouvelle presse medicale, 1978, Sep-20, Volume: 7, Issue:31 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Tolerance; Heart Rate; Humans; Hypertension; Metoprolol; Pindolol; Practolol; Time Factors	1978
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
Beta-adrenergic antagonists in the treatment of patients with heart disease. Disease-a-month : DM, 1981, Volume: 27, Issue:9 Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Cardiomyopathy, Hypertrophic; Coronary Disease; Female; Heart Diseases; Heart Failure; Humans; Hypertension; Metoprolol; Mitral Valve Prolapse; Mitral Valve Stenosis; Nadolol; Nervous System Diseases; Pindolol; Pregnancy; Pregnancy Complications, Cardiovascular; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Structure-Activity Relationship; Timolol	1981

Other Studies

39 other study(ies) available for alprenolol and acebutolol

Article	Year
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models. Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1 Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists. Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3 Topics: Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Liquid; Mathematics; Pharmaceutical Preparations; Software	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography. Journal of medicinal chemistry, 2009, May-28, Volume: 52, Issue:10 Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
[Comparison of the pA2 of various beta blocking agents]. La Nouvelle presse medicale, 1975, Dec-31, Volume: 4, Issue:46 Suppl Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; In Vitro Techniques; Oxprenolol; Pindolol; Practolol; Propranolol; Trachea	1975
[Indications and limits for the use of beta-blockaders (beta-adrenergic inhibitors) in the treatment of hypertension]. Semaine des hopitaux. Therapeutique, 1977, Volume: 53, Issue:2 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Humans; Hypertension; Propranolol	1977
[Editorial: Importance of cardioselectivity and sympaticomimetric potential of beta-blockers (author's transl)]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1975, Sep-30, Volume: 64, Issue:39 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Vessels; Ethanolamines; Heart; Humans; Oxprenolol; Pindolol; Practolol; Propranolol; Sotalol; Sympathomimetics	1975
Renal effects of beta-adrenoceptor blockade. Kidney international, 1980, Volume: 18, Issue:5 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Angiotensin II; Animals; Blood Pressure; Cardiac Output; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Pindolol; Propranolol; Renin; Sodium	1980
Variability in the preventive action of the B-blockers on genetic hypertension in the rat. Paroi arterielle, 1980, Volume: 6, Issue:4 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Pressure; Dose-Response Relationship, Drug; Hypertension; Male; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rats; Rats, Inbred Strains; Species Specificity; Time Factors	1980
Displacement of [3H]dihydroalprenolol binding from rat heart and lung by acebutolol, diacetolol and D-diacetolol. The Journal of pharmacy and pharmacology, 1983, Volume: 35, Issue:3 Topics: Acebutolol; Alprenolol; Animals; Binding, Competitive; Dihydroalprenolol; In Vitro Techniques; Isomerism; Lung; Myocardium; Rats; Rats, Inbred Strains; Tritium	1983
An antiidiotypic antibody that recognizes the beta-adrenergic receptor. The Journal of clinical investigation, 1982, Volume: 69, Issue:5 Topics: Acebutolol; Alprenolol; Animals; Antibody Affinity; Antibody Formation; Binding Sites, Antibody; Immunization; Immunoglobulin Idiotypes; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, beta	1982
Binding of [3H]-dihydroalprenolol and [3H]-acetobutolol to human blood platelets is not related to occupancy of beta-adrenoceptors. Thrombosis research, 1983, Mar-15, Volume: 29, Issue:6 Topics: Acebutolol; Alprenolol; Blood Platelets; Butoxamine; Dihydroalprenolol; Humans; Isoproterenol; Kinetics; Practolol; Propranolol; Receptors, Adrenergic; Receptors, Adrenergic, beta	1983
Quantitative structure-pharmacokinetic relationships (QSPR) of beta blockers derived using neural networks. Journal of pharmaceutical sciences, 1995, Volume: 84, Issue:7 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Models, Statistical; Neural Networks, Computer; Pharmacokinetics; Structure-Activity Relationship	1995
Drug delivery studies in Caco-2 monolayers. Synthesis, hydrolysis, and transport of O-cyclopropane carboxylic acid ester prodrugs of various beta-blocking agents. Pharmaceutical research, 1995, Volume: 12, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Cells, Cultured; Drug Delivery Systems; Esters; Humans; Hydrolysis; Mathematics; Permeability; Time Factors	1995
Toxicity of beta-blockers in a rat whole embryo culture: concentration-response relationships and tissue concentrations. Archives of toxicology, 1994, Volume: 68, Issue:6 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dose-Response Relationship, Drug; Embryo, Mammalian; Embryonic and Fetal Development; In Vitro Techniques; Metoprolol; Pindolol; Propranolol; Rats; Rats, Wistar	1994
Beta-blockers inhibit the modification of low-density lipoproteins by sodium hypochlorite in vitro. Chemistry and physics of lipids, 1997, Jan-17, Volume: 85, Issue:1 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Atenolol; Bepridil; Biphenyl Compounds; Chemical Phenomena; Chemistry; Cholesterol Esters; Diclofenac; Free Radicals; Humans; Lipoproteins, LDL; Macrophages; Molecular Structure; Oxprenolol; Particle Size; Picrates; Sodium Hypochlorite; Spectrum Analysis; Thiobarbituric Acid Reactive Substances	1997
Relationship between amount of beta-blockers permeating through the stratum corneum and skin irritation after application of beta-blocker adhesive patches to guinea pig skin. Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:4 Topics: Acebutolol; Administration, Cutaneous; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Dermatitis, Irritant; Guinea Pigs; Male; Oxprenolol; Skin; Skin Absorption; Timolol	1997
Evaluation of the immobilized artificial membrane phosphatidylcholine. Drug discovery column for high-performance liquid chromatographic screening of drug-membrane interactions. Journal of chromatography. A, 1998, Mar-27, Volume: 800, Issue:2 Topics: Acebutolol; Acetonitriles; Adrenergic beta-Antagonists; Alprenolol; Aniline Compounds; Atenolol; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Membranes, Artificial; Metoprolol; Models, Chemical; Osmolar Concentration; Oxprenolol; Phosphatidylcholines; Pindolol; Propranolol; Reproducibility of Results; Timolol	1998
In vitro permeability of eight beta-blockers through Caco-2 monolayers utilizing liquid chromatography/electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS, 1998, Volume: 33, Issue:7 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Atenolol; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Chromatography, Liquid; Epithelial Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Mass Spectrometry; Metoprolol; Molecular Structure; Oxprenolol; Pindolol; Propranolol; Research Design; Timolol	1998
1H and 13C NMR characteristics of β-blockers. Magnetic resonance in chemistry : MRC, 2011, Volume: 49, Issue:5 Topics: Acebutolol; Acids; Adrenergic beta-Antagonists; Alkalies; Alprenolol; Atenolol; Carbazoles; Carbon Isotopes; Carvedilol; Nuclear Magnetic Resonance, Biomolecular; Pindolol; Propanolamines; Propranolol; Protons; Timolol	2011
Acebutolol and alprenolol metabolism predictions: comparative study of electrochemical and cytochrome P450-catalyzed reactions using liquid chromatography coupled to high-resolution mass spectrometry. Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:18 Topics: Acebutolol; Alprenolol; Animals; Catalysis; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Electrochemical Techniques; Hydroxylation; Mass Spectrometry; Microsomes, Liver; Models, Theoretical; Oxidation-Reduction; Rats	2013