alprazolam has been researched along with morphine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.90) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 11 (37.93) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 3 (10.34) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Coda, BA; Hill, HF; Mackie, A | 1 |
| Cohen, MH; Johnston-Anderson, A; Krasnow, SH; Wadleigh, RG | 1 |
| Franklin, SR; Tang, AH | 1 |
| Inturrisi, CE; Yoburn, BC | 1 |
| DeTurck, KH; Miller, J; Routzahn, BK; Vogel, WH | 1 |
| Pick, CG | 1 |
| Jenck, F; Le Pen, G; Moreau, JL; Wichmann, J | 1 |
| Krsiak, M; Moravec, V; Votava, M | 1 |
| Loscalzo, LM; Marder, M; Paladini, AC; Wasowski, C | 1 |
| Ajami, M; Habibey, R; Pazoki-Toroudi, HR | 1 |
| Aug, I; Bregin, A; Innos, J; Mazitov, T; Philips, MA; Vasar, E | 1 |
| Buratti, E; Cerioni, A; Cingolani, M; Cippitelli, M; Froldi, R; Mietti, G; Scendoni, R | 1 |
| Bolaños-Guzmán, CA; Cardona-Acosta, AM; Enriquez Marti, G; Gnecco, T; Parise, LF; Sial, OK | 1 |
| García-Algar, O; López-Vílchez, MA; Martín, I; Mur, A; Pacifici, R; Pellegrini, M; Pichini, S; Rossi, S | 1 |
| Marin, SJ; McMillin, GA | 1 |
| Concheiro, M; Cruz, A; de-Castro-Ríos, A; Lendoiro, E; López-Rabuñal, A; López-Rivadulla, M | 1 |
2 review(s) available for alprazolam and morphine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of intractable dyspnea: clinical and ethical issues.
Topics: Alprazolam; Codeine; Diazepam; Dyspnea; Ethics, Medical; Humans; Infusions, Intravenous; Morphine; Neoplasms; Promethazine; Randomized Controlled Trials as Topic | 1992 |
1 trial(s) available for alprazolam and morphine
| Article | Year |
|---|---|
Influence of alprazolam on opioid analgesia and side effects during steady-state morphine infusions.
Topics: Adult; Alprazolam; Analgesia; Drug Synergism; Homeostasis; Humans; Infusions, Intravenous; Male; Morphine; Pilot Projects; Self-Assessment | 1992 |
26 other study(ies) available for alprazolam and morphine
| Article | Year |
|---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
The discriminative stimulus effects of diazepam in rats at two training doses.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Buspirone; Carbolines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Flumazenil; Male; Morphine; Pentobarbital; Pyrazoles; Pyridazines; Rats; Rats, Inbred Strains; Triazolam | 1991 |
Modification of the response to opioid and nonopioid drugs by chronic opioid antagonist treatment.
Topics: Alprazolam; Analgesia; Animals; Ataxia; Cocaine; Drug Implants; Kinetics; Male; Methadone; Mice; Morphine; Naloxone; Narcotics | 1988 |
Effects of psychoactive drugs on plasma catecholamines during stress in rats.
Topics: Alprazolam; Amphetamine; Animals; Benzodiazepines; Diazepam; Epinephrine; Humans; Male; Morphine; Norepinephrine; Pentobarbital; Psychotropic Drugs; Rats; Rats, Inbred Strains; Stress, Psychological; Time Factors | 1984 |
Strain differences in mice antinociception: relationship between alprazolam and opioid receptor subtypes.
Topics: Alprazolam; Analgesia; Animals; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred Strains; Morphine; Pain Measurement; Receptors, Opioid | 1996 |
The orphanin receptor agonist RO 64-6198 does not induce place conditioning in rats.
Topics: Alprazolam; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Conditioning, Operant; Dose-Response Relationship, Drug; Imidazoles; Male; Morphine; Motor Activity; Nociceptin Receptor; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spiro Compounds | 2002 |
Effects of alprazolam and fluoxetine on morphine sensitization in mice.
Topics: Alprazolam; Animals; Fluoxetine; Male; Mice; Mice, Inbred ICR; Morphine; Motor Activity; Narcotic Antagonists; Narcotics | 2002 |
Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines.
Topics: Acetic Acid; Alprazolam; Analgesics; Animals; Behavior, Animal; Benzodiazepines; Dose-Response Relationship, Drug; Drug Synergism; Flunitrazepam; Hesperidin; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Mice; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Receptors, Opioid | 2008 |
Pre-medication and renal pre-conditioning: a role for alprazolam, atropine, morphine and promethazine.
Topics: Adjuvants, Anesthesia; Alprazolam; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Atropine; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Ischemic Preconditioning; Kidney; Morphine; Premedication; Promethazine; Rats; Rats, Wistar; Reperfusion Injury | 2010 |
Drug overdose deaths--Florida, 2003-2009.
Topics: Alprazolam; Cause of Death; Cocaine; Drug Overdose; Florida; Humans; Illicit Drugs; Methadone; Morphine; Mortality; Oxycodone; Prescription Drugs | 2011 |
Increased sensitivity to psychostimulants and GABAergic drugs in Lsamp-deficient mice.
Topics: Alprazolam; Animals; Behavior, Animal; Cell Adhesion Molecules, Neuronal; Central Nervous System Depressants; Central Nervous System Stimulants; Cocaine; Diazepam; Disease Models, Animal; Dizocilpine Maleate; Ethanol; Female; GABA Modulators; Gene Knockout Techniques; GPI-Linked Proteins; Locomotion; Male; Maze Learning; Mice; Mice, Knockout; Morphine; Neuroprotective Agents; Phenotype; Receptors, GABA-A | 2019 |
Validation of an HPLC-HR-MS Method for the Determination and Quantification of Six Drugs (Morphine, Codeine, Methadone, Alprazolam, Clonazepam and Quetiapine) in Nails.
Topics: Alprazolam; Benzodiazepines; Chromatography, High Pressure Liquid; Clonazepam; Codeine; Humans; Methadone; Morphine; Nails; Quetiapine Fumarate | 2023 |
Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway.
Topics: Alprazolam; Animals; Male; Mice; Mice, Inbred C57BL; Morphine; Nucleus Accumbens; Reward; Second Messenger Systems; Ventral Tegmental Area | 2023 |
Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Diagnosis, Differential; Female; Fetal Blood; Hair; Humans; Infant, Newborn; Male; Maternal Exposure; Maternal-Fetal Exchange; Meconium; Neonatal Abstinence Syndrome; Oxygen Inhalation Therapy; Placenta; Pregnancy; Sepsis; Streptococcal Infections; Streptococcus agalactiae; Substance Abuse Detection; Treatment Outcome; Urine | 2007 |
LC-MS/MS analysis of 13 benzodiazepines and metabolites in urine, serum, plasma, and meconium.
Topics: Alprazolam; Benzodiazepines; Chromatography, Liquid; Clonazepam; Flurazepam; Humans; Infant, Newborn; Meconium; Nordazepam; Oxazepam; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Triazolam | 2010 |
LC-MS-MS Method for the Determination of Antidepressants and Benzodiazepines in Meconium.
Topics: Alprazolam; Antidepressive Agents; Benzodiazepines; Chromatography, Liquid; Clonazepam; Forensic Toxicology; Humans; Limit of Detection; Meconium; Nordazepam; Oxazepam; Reproducibility of Results; Solid Phase Extraction; Substance Abuse Detection; Tandem Mass Spectrometry; Venlafaxine Hydrochloride; Zolpidem | 2020 |