alprazolam and hypericum

alprazolam has been researched along with hypericum in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boulton, DW; Carson, SW; DeVane, CL; Markowitz, JS; Nahas, Z; Risch, SC1
Chavin, KD; DeVane, CL; Donovan, JL; Markowitz, JS; Ruan, Y; Taylor, RM; Wang, JS1
Arold, G; Bauer, S; Diefenbach, K; Donath, F; Friede, M; Henneicke-von Zepelin, HH; Maurer, A; Roots, I1
Adiwidjaja, J; Boddy, AV; McLachlan, AJ1

Trials

1 trial(s) available for alprazolam and hypericum

ArticleYear
No relevant interaction with alprazolam, caffeine, tolbutamide, and digoxin by treatment with a low-hyperforin St John's wort extract.
    Planta medica, 2005, Volume: 71, Issue:4

    Topics: Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Caffeine; Cardiotonic Agents; Central Nervous System Stimulants; Digoxin; Double-Blind Method; Drug Interactions; Female; Humans; Hypericum; Hypoglycemic Agents; Male; Middle Aged; Phytotherapy; Plant Extracts; Tolbutamide; Treatment Outcome

2005

Other Studies

4 other study(ies) available for alprazolam and hypericum

ArticleYear
Effect of St. John's wort (Hypericum perforatum) on cytochrome P-450 2D6 and 3A4 activity in healthy volunteers.
    Life sciences, 2000, Jan-21, Volume: 66, Issue:9

    Topics: Adult; Alprazolam; Area Under Curve; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; Drug Interactions; Female; Half-Life; Humans; Hypericum; Male; Mixed Function Oxygenases; Plant Extracts; Plants, Medicinal

2000
Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme.
    JAMA, 2003, Sep-17, Volume: 290, Issue:11

    Topics: Adult; Alprazolam; Cross-Over Studies; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Drug Interactions; Enzyme Induction; Female; Humans; Hypericum; Male; Plant Extracts; Substrate Specificity

2003
Herbals and traditional meds collide.
    Health news (Waltham, Mass.), 2003, Volume: 9, Issue:11

    Topics: Alprazolam; Anti-Anxiety Agents; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Hypericum; Phytotherapy

2003
Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John's Wort.
    Clinical pharmacokinetics, 2019, Volume: 58, Issue:7

    Topics: Adult; Alprazolam; Antineoplastic Agents; Computer Simulation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Humans; Hypericum; Imatinib Mesylate; Intestinal Mucosa; Liver; Male; Midazolam; Middle Aged; Models, Biological; Phloroglucinol; Terpenes

2019