alprazolam has been researched along with cimetidine in 19 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (15.79) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 9 (47.37) | 29.6817 |
2010's | 7 (36.84) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B | 1 |
Topliss, JG; Yoshida, F | 1 |
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
Artursson, P; Mateus, A; Matsson, P | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Desager, JP; Harvengt, C; Hulhoven, R; Pourbaix, S; Smith, RB | 1 |
Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI | 1 |
Abernethy, DR; Divoll, M; Greenblatt, DJ; Harmatz, JS; Moschitto, LJ; Shader, RI | 1 |
Green, CE; Hirota, N; Ito, K; Iwatsubo, T; Shimada, N; Sugiyama, Y; Suzuki, H; Tyson, CA | 1 |
Constantino, L; Dias, C; Dias, M; Soveral, G; Testa, B | 1 |
1 review(s) available for alprazolam and cimetidine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for alprazolam and cimetidine
Article | Year |
---|---|
Interaction of cimetidine with the triazolobenzodiazepines alprazolam and triazolam.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Drug Interactions; Female; Guanidines; Humans; Male; Metabolic Clearance Rate; Middle Aged; Triazolam | 1983 |
17 other study(ies) available for alprazolam and cimetidine
Article | Year |
---|---|
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Pharmacokinetic consequences of long term coadministration of cimetidine and triazolobenzodiazepines, alprazolam and triazolam, in healthy subjects.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Drug Interactions; Female; Half-Life; Humans; Kinetics; Male; Time Factors; Triazolam | 1985 |
Pharmacokinetics of alprazolam.
Topics: Age Factors; Alprazolam; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Body Weight; Cimetidine; Female; Humans; Kinetics; Male; Sex Factors | 1983 |
In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans.
Topics: Adult; Alprazolam; Anti-Anxiety Agents; Area Under Curve; Cimetidine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes b5; Female; Humans; Intestinal Mucosa; Ketoconazole; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Recombinant Proteins | 2001 |
Screening of the inhibitory effect of xenobiotics on alcohol metabolism using S9 rat liver fractions.
Topics: Alcohol Dehydrogenase; Alprazolam; Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ethanol; Flunitrazepam; Fomepizole; Inhibitory Concentration 50; Liver; Pyrazoles; Rats; Rats, Wistar; Ribosomal Protein S9; Ribosomal Proteins; Tramadol; Xenobiotics | 2012 |