alphaxalone has been researched along with picrotoxin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (40.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Capper, HR; Johnston, GA; Kerr, DI; Ong, J | 1 |
| David, JA; Pinnock, RD; Sattelle, DB; Wafford, KA | 1 |
| Kerr, DI; Ong, J | 1 |
| Cottrell, GA; Lambert, JJ; Peters, JA | 1 |
| Maksay, G; Simonyi, M | 1 |
| Simmonds, MA; Turner, JP | 2 |
| Ramanjaneyulu, R; Ticku, MK | 1 |
| Ai, J; Kahnberg, P; Nielsen, M; Saederup, E; Squires, RF; Sterner, O; Witt, MR | 1 |
| Jensen, AA | 1 |
| Biggio, G; Concas, A; Mascia, MP; Sanna, E; Santoro, G; Serra, M | 1 |
| Johnston, GA; Kerr, DI; Ong, J | 1 |
| Bormann, J; Feigenspan, A; Wässle, H | 1 |
| Amato, F; Biggio, G; Deserra, T; Motzo, C; Murgia, A; Sanna, E | 1 |
| Biggio, G; Casula, A; Murgia, A; Sanna, E | 1 |
| Greenfield, LJ; Macdonald, RL; Neelands, TR; Turner, RS; Zhang, J | 1 |
| Chen, CL; Chiu, TH; Yang, YR | 1 |
| Bence, M; Everest, H; Forrest-Owen, W; Lightman, SL; McArdle, CA; Williams, B | 1 |
| Feigenspan, A; Gustincich, S; Raviola, E | 1 |
| Minami, K; Okamoto, T; Shibuya, I; Shigematsu, A; Shiraishi, M; Ueno, S; Ueta, Y; Uezono, Y; Yanagihara, N | 1 |
20 other study(ies) available for alphaxalone and picrotoxin
| Article | Year |
|---|---|
Cortisone: a potent GABAA antagonist in the guinea-pig isolated ileum.
Topics: Androstanes; Animals; Azasteroids; Cortisone; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hydrocortisone; Ileum; In Vitro Techniques; Male; Models, Molecular; Muscle Contraction; Muscle, Smooth; Picrotoxin; Sesterterpenes | 1990 |
GABA receptors on the cell-body membrane of an identified insect motor neuron.
Topics: Androstanes; Animals; Azasteroids; Bicuculline; Chlorides; Cockroaches; Dibenzazepines; Dose-Response Relationship, Drug; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Ion Channels; Male; Membrane Potentials; Microelectrodes; Motor Neurons; Nipecotic Acids; Periplaneta; Picrotoxin; Receptors, GABA-A | 1988 |
Modulation of spontaneous motility by GABAA receptor antagonism in the guinea pig isolated ileum.
Topics: 3-Mercaptopropionic Acid; Acetylcholine; Androstanes; Animals; Azasteroids; Bicuculline; Carbachol; Female; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Picrotoxin; Time Factors | 1989 |
An electrophysiological investigation of the characteristics and function of GABAA receptors on bovine adrenomedullary chromaffin cells.
Topics: Acetylcholine; Action Potentials; Adrenal Medulla; Androstanes; Animals; Azasteroids; Bicuculline; Cattle; Cell Membrane; Chloride Channels; Chlorides; Chromaffin System; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Proteins; Picrotoxin; Propanidid; Receptors, Cholinergic; Receptors, GABA-A | 1989 |
Kinetic modulation by GABAergic agents of high- and low-affinity binding of [3H]methyl beta-carboline-3-carboxylate.
Topics: Androstanes; Animals; Azasteroids; Carbolines; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Half-Life; Kinetics; Male; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes | 1988 |
Antagonism of inhibitory amino acids by the steroid derivative RU5135.
Topics: Amino Acids; Androstanes; Animals; Azasteroids; Bicuculline; Electrophysiology; Glycine; In Vitro Techniques; Medulla Oblongata; Muscimol; Optic Nerve; Picrotoxin; Rats; Steroids, Heterocyclic; Strychnine | 1985 |
RO5-4864 inhibits the binding of [35S]t-butylbicyclophosphorothionate to rat brain membranes.
Topics: Androstanes; Animals; Azasteroids; Benzodiazepinones; Bicuculline; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; Cell Membrane; Cerebellum; Cerebral Cortex; Dose-Response Relationship, Drug; Flumazenil; Hippocampus; Male; Picrotoxin; Radioligand Assay; Rats | 1984 |
Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.
Topics: Allosteric Regulation; Androstanes; Animals; Azasteroids; Binding Sites; Biphenyl Compounds; Cell Membrane; Central Nervous System Depressants; Cerebellum; Diflunisal; Drugs, Chinese Herbal; Flunitrazepam; GABA Antagonists; gamma-Aminobutyric Acid; Kinetics; Lignans; Muscimol; Picrotoxin; Propofol; Prosencephalon; Rats; Receptors, GABA-A; Tritium | 1999 |
Functional characterisation of human glycine receptors in a fluorescence-based high throughput screening assay.
Topics: Androstanes; Azasteroids; beta-Alanine; Cell Line; Dose-Response Relationship, Drug; Fluorescence; Glycine; Glycine Agents; Humans; Membrane Potentials; Patch-Clamp Techniques; Picrotoxin; Receptors, Glycine; Strychnine; Taurine; Transfection | 2005 |
The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex.
Topics: Anesthetics; Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chloride Channels; gamma-Aminobutyric Acid; Male; Membrane Proteins; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Inbred Strains | 1990 |
Modulation of the GABAA receptor complex by steroids in slices of rat cuneate nucleus.
Topics: Androsterone; Anesthetics; Animals; Electric Stimulation; In Vitro Techniques; Isomerism; Medulla Oblongata; Muscimol; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Steroids; Structure-Activity Relationship | 1989 |
Alfaxalone potentiates and mimics GABA-induced contractile responses in the guinea-pig isolated ileum.
Topics: Anesthetics; Animals; Bicuculline; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Picrotoxin; Pregnanediones; Sesterterpenes | 1988 |
Pharmacology of GABA receptor Cl- channels in rat retinal bipolar cells.
Topics: Animals; Animals, Newborn; Bicuculline; Cells, Cultured; Chloride Channels; Flunitrazepam; gamma-Aminobutyric Acid; Ion Channels; Membrane Potentials; Membrane Proteins; Neurons; Pentobarbital; Photoreceptor Cells; Picrotoxin; Pregnanediones; Rats; Receptors, GABA-A; Sesterterpenes; Strychnine | 1993 |
Expression of native GABAA receptors in Xenopus oocytes injected with rat brain synaptosomes.
Topics: Anesthetics; Animals; Brain; Cell Membrane; Chloride Channels; Chlorides; Diazepam; Female; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Rats; Receptors, GABA-A; Synaptosomes; Xenopus laevis; Zinc Compounds | 1996 |
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
Topics: Anesthetics; Animals; Binding Sites; Chlorides; Etomidate; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1997 |
GABAA receptor pharmacology and subtype mRNA expression in human neuronal NT2-N cells.
Topics: Anticonvulsants; Bicuculline; Carbolines; Convulsants; Diazepam; Diuretics; DNA Primers; Furosemide; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Lanthanum; Neurons; Patch-Clamp Techniques; Pentobarbital; Phenobarbital; Picrotoxin; Polymerase Chain Reaction; Pregnanediones; Pregnenolone; Pyridines; Receptors, GABA-A; RNA, Messenger; Teratocarcinoma; Triazoles; Tumor Cells, Cultured; Zinc; Zolpidem | 1998 |
Activation of rat locus coeruleus neuron GABA(A) receptors by propofol and its potentiation by pentobarbital or alphaxalone.
Topics: Anesthetics; Anesthetics, Intravenous; Animals; Baclofen; Barium Compounds; Bicuculline; Chlorides; Diazepam; Drug Synergism; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Ionophores; Locus Coeruleus; Male; Neurons; Pentobarbital; Picrotoxin; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Zinc Compounds | 1999 |
GABAA receptor mediated elevation of Ca2+ and modulation of gonadotrophin-releasing hormone action in alphaT3-1 gonadotropes.
Topics: Anesthetics; Animals; Baclofen; Bicuculline; Biological Transport; Calcium; Calcium Channel Blockers; Cells, Cultured; Chlorides; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Mice; Muscimol; Nifedipine; Picrotoxin; Pituitary Gland; Pregnanediones; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Pharmacology of GABA(A) receptors of retinal dopaminergic neurons.
Topics: Alkaline Phosphatase; Animals; Benzodiazepines; Bicuculline; Binding Sites; Dopamine; Dose-Response Relationship, Drug; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Mice; Mice, Transgenic; Neurons; Osmolar Concentration; Patch-Clamp Techniques; Picrotoxin; Pregnanediones; Protein Isoforms; Receptors, GABA-A; Retina; Sesterterpenes; Triazoles; Zinc | 2000 |
A neurosteroid anesthetic, alphaxalone, inhibits nicotinic acetylcholine receptors in cultured bovine adrenal chromaffin cells.
Topics: Anesthetics; Animals; Calcium Channel Blockers; Cattle; Cells, Cultured; Chromaffin Cells; gamma-Aminobutyric Acid; Nicotine; Patch-Clamp Techniques; Perfusion; Picrotoxin; Pregnanediones; Receptors, GABA-A; Receptors, Nicotinic | 2002 |