alphaxalone has been researched along with etomidate in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 6 (28.57) | 29.6817 |
| 2010's | 9 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Mascia, MP; Pau, A; Sanna, E; Sanna, S; Talani, G | 1 |
| Atucha, E; Berger, ML; Hammerschmidt, F; Sieghart, W; Zolle, I | 1 |
| Biziere, K; Keane, PE | 1 |
| Erhardt, W; Ittner, J; Kramer, A | 1 |
| Elliott, RC | 1 |
| Benoit, E | 1 |
| Biggio, G; Casula, A; Murgia, A; Sanna, E | 1 |
| Finn, SE; Harrison, NL; Rick, CE; Ye, Q | 1 |
| Carlson, BX; Engblom, AC; Kristiansen, U; Olsen, RW; Schousboe, A | 1 |
| Chang, CS; Olcese, R; Olsen, RW | 1 |
| Krähenbühl, K; Lambert, S; Rudolph, U; Siegwart, R | 1 |
| Asproni, B; Biggio, G; Busonero, F; Cerri, R; Maciocco, E; Mascia, MP; Pau, A; Sanna, E; Talani, G | 1 |
| Domínguez Pérez, JM; Fernández Sarmiento, JA; Gómez-Villamandos, RJ; Granados Machuca, MM; Muñoz-Rascón, P; Navarrete-Calvo, R; Quirós Carmona, S; Rodríguez, JM | 1 |
| Akk, G; Eaton, MM; Li, P; Steinbach, JH | 1 |
| Andaluz, A; Domínguez, E; Espada, Y; Fresno, L; García, F; Novellas, R; Rivera Del Álamo, MM; Santos, L | 1 |
| Chandra, D; Homanics, GE; Iyer, SV | 1 |
| Akk, G; Li, P | 1 |
| Forman, SA; Stern, AT | 1 |
| Forman, SA; Hotta, M; Nourmahnad, A; Stern, AT; Stewart, DS; Szabo, A; Ziemba, AM | 1 |
| Bruzik, KS; Kent, DE; Miller, KW; Savechenkov, PY | 1 |
1 review(s) available for alphaxalone and etomidate
| Article | Year |
|---|---|
The effects of general anaesthetics on GABAergic synaptic transmission.
Topics: Anesthesia, General; Anesthetics; Animals; Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Ethanol; Etomidate; Humans; Pregnanediones; Receptors, GABA-A; Synaptic Transmission | 1987 |
20 other study(ies) available for alphaxalone and etomidate
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles.
Topics: Amino Acid Sequence; Animals; Behavior, Animal; Brain; Female; GABA-A Receptor Agonists; Humans; Imidazoles; In Vitro Techniques; Male; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Protein Subunits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Recombinant Proteins; Reflex; Stereoisomerism; Structure-Activity Relationship; Xenopus laevis | 2005 |
Structure-activity relationship of etomidate derivatives at the GABA(A) receptor: Comparison with binding to 11beta-hydroxylase.
Topics: Anesthetics, Intravenous; Animals; Binding Sites; Chemistry, Pharmaceutical; Drug Design; Etomidate; Inhibitory Concentration 50; Male; Models, Chemical; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Stereoisomerism; Steroid 11-beta-Hydroxylase; Structure-Activity Relationship | 2009 |
[Comparative studies of short-term anesthesia with alfentanil/etomidate and alphaxalone/alphadolone in cats].
Topics: Adjuvants, Anesthesia; Alfentanil; Anesthesia, Intravenous; Anesthetics; Animals; Cats; Etomidate; Fentanyl; Heart Rate; Imidazoles; Pregnanediones; Reflex; Respiration | 1985 |
The action of intravenous anaesthetic and central depressant drugs on the contractures elicited by tetraethylammonium in the chick biventer cervicis muscle.
Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Central Nervous System Depressants; Chickens; Chloralose; Diazepam; Drug Synergism; Ethanol; Etomidate; In Vitro Techniques; Methohexital; Muscle Contraction; Neck Muscles; Paraldehyde; Pregnanediones; Propanidid; Tetraethylammonium; Tetraethylammonium Compounds; Thiopental; Urethane | 1985 |
Effects of intravenous anaesthetics on nerve axons.
Topics: Action Potentials; Anesthetics, Intravenous; Animals; Axons; Dose-Response Relationship, Drug; Etomidate; Ion Channel Gating; Ketamine; Membrane Potentials; Nerve Fibers, Myelinated; Potassium; Potassium Channels; Pregnanediones; Rana esculenta; Sodium; Sodium Channels; Time Factors | 1995 |
Differential subunit dependence of the actions of the general anesthetics alphaxalone and etomidate at gamma-aminobutyric acid type A receptors expressed in Xenopus laevis oocytes.
Topics: Anesthetics; Animals; Binding Sites; Chlorides; Etomidate; Oocytes; Picrotoxin; Pregnanediones; Pyridazines; Receptors, GABA-A; Recombinant Proteins; Xenopus laevis | 1997 |
Neurosteroids act on the GABA(A) receptor at sites on the N-terminal side of the middle of TM2.
Topics: Anesthetics; Cell Line; Ethanol; Etomidate; GABA-A Receptor Agonists; Humans; Patch-Clamp Techniques; Pregnanediones; Receptors, Glycine; Steroids | 1998 |
A single glycine residue at the entrance to the first membrane-spanning domain of the gamma-aminobutyric acid type A receptor beta(2) subunit affects allosteric sensitivity to GABA and anesthetics.
Topics: Allosteric Regulation; Amino Acid Sequence; Anesthetics; Animals; Cells, Cultured; Chloride Channels; Electrophysiology; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Pentobarbital; Pregnanediones; Propofol; Protein Conformation; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Sequence Homology, Amino Acid; Spodoptera | 2000 |
A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation.
Topics: Adjuvants, Anesthesia; Allosteric Site; Amino Acid Sequence; Anesthetics; Anesthetics, Intravenous; Animals; Cloning, Molecular; DNA Mutational Analysis; Dose-Response Relationship, Drug; Etomidate; Kinetics; Ligands; Models, Biological; Molecular Sequence Data; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Pentobarbital; Point Mutation; Pregnanediones; Propofol; Protein Structure, Tertiary; Rats; Receptors, GABA-A; Recombinant Proteins; RNA, Messenger; Xenopus | 2003 |
Mutational analysis of molecular requirements for the actions of general anaesthetics at the gamma-aminobutyric acidA receptor subtype, alpha1beta2gamma2.
Topics: Anesthetics, General; Animals; Cells, Cultured; Enflurane; Etomidate; gamma-Aminobutyric Acid; Humans; Point Mutation; Pregnanediones; Propofol; Protein Subunits; Rats; Receptors, GABA-A; Recombinant Proteins | 2003 |
Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors.
Topics: Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Etomidate; Female; Flunitrazepam; GABA Modulators; gamma-Aminobutyric Acid; Glycine; Humans; Hydrocarbons, Halogenated; Imidazoles; Male; Membrane Potentials; Oocytes; Pentobarbital; Pregnanediones; Propofol; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Glycine; Receptors, Serotonin, 5-HT3; Serotonin; Tritium; Xenopus laevis | 2005 |
Comparison of the cardiopulmonary parameters after induction of anaesthesia with alphaxalone or etomidate in dogs.
Topics: Anesthesia, Intravenous; Animals; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Body Temperature; Dogs; Etomidate; Female; Heart; Heart Rate; Lung; Male; Pregnanediones; Respiratory Rate; Stroke Volume; Vascular Resistance | 2012 |
The benzodiazepine diazepam potentiates responses of α1β2γ2L γ-aminobutyric acid type A receptors activated by either γ-aminobutyric acid or allosteric agonists.
Topics: Anesthetics; Animals; Binding Sites; Diazepam; Drug Synergism; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Humans; In Vitro Techniques; Patch-Clamp Techniques; Pentobarbital; Pregnanediones; Rats; Receptors, GABA-A | 2013 |
Doppler evaluation of the effects of propofol, etomidate and alphaxalone on fetoplacental circulation hemodynamics in the pregnant ewe.
Topics: Anesthesia, Obstetrical; Anesthetics, Intravenous; Animals; Animals, Inbred Strains; Blood Flow Velocity; Etomidate; Female; Fetus; Heart Rate, Fetal; Placental Circulation; Pregnancy; Pregnanediones; Propofol; Pulsatile Flow; Random Allocation; Sheep, Domestic; Ultrasonography, Doppler; Ultrasonography, Prenatal; Umbilical Arteries; Vascular Resistance | 2013 |
GABAA-R α4 subunits are required for the low dose locomotor stimulatory effect of alphaxalone, but not for several other behavioral responses to alphaxalone, etomidate or propofol.
Topics: Anesthetics; Animals; Etomidate; Female; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Pregnanediones; Propofol; Protein Subunits; Receptors, GABA-A | 2014 |
Synaptic-type α1β2γ2L GABAA receptors produce large persistent currents in the presence of ambient GABA and anesthetic drugs.
Topics: Anesthetics; Animals; Cell Line; Chromosome Pairing; Etomidate; gamma-Aminobutyric Acid; HEK293 Cells; Humans; Pentobarbital; Pregnanediones; Propofol; Rats; Receptors, GABA-A | 2015 |
A Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptors.
Topics: Amino Acid Substitution; Anesthetics; Anesthetics, Intravenous; Animals; Barbiturates; Cysteine; Electrophysiological Phenomena; Etomidate; Female; Pregnanediones; Propofol; Receptors, GABA; Xenopus laevis | 2016 |
Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.
Topics: Amino Acid Substitution; Anesthetics, Intravenous; Animals; Barbiturates; Binding Sites; Cysteine; Etomidate; Female; Ion Channel Gating; Mutation; Pregnanediones; Propofol; Receptors, GABA-A; Tryptophan; Xenopus | 2016 |
Binding site location on GABA
Topics: Anesthetics, Intravenous; Animals; Behavior, Animal; Binding Sites; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Etomidate; Larva; Mephobarbital; Pregnanediones; Receptors, GABA-A; Xenopus laevis | 2019 |