Page last updated: 2024-08-26

alphaxalone and alphadolone

alphaxalone has been researched along with alphadolone in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199036 (76.60)18.7374
1990's7 (14.89)18.2507
2000's3 (6.38)29.6817
2010's1 (2.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
al-Khawashki, MI; el-Gawhery, N; el-Sherbiny, AM; Ghaleb, HA; Madkour, MK; Radwan, AM1
al-Khawashki, MI; el-Gawhary, N; el-Sherbiny, AM; Ghaleb, HA; Madkour, MK; Radwan, AM3
Holder, DS1
Hartell, NA; Headley, MP1
Hashim, MA; Waterman, AE1
Suzuki, T; Tomioka, M; Uchida, MK1
Hale, GJ1
Peterson, SL1
Denny, C; Harvey, B; Kaiser, S; Young, J1
Halsey, MJ; Wardley-Smith, B; Wood, S1
Lögdberg, B1
Bancroft, BJ; Johnstone, IP1
Emanuele, MA; Emanuele, NV; Kirsteins, L; Lawrence, AM; Reda, D; Tentler, J1
Burroughs, RE; Ebedes, H; Gandini, GC; Keffen, RH1
Coppola, L; Demo, P; Pellizzari, A; Vendramin, ML1
Clarke, RW; Matthews, B1
Gavin, JB; Sage, MD; West, EJ1
Roelofse, JA; Shipton, EA1
Erhardt, W; Ittner, J; Kramer, A1
Holly, JM; Makin, HL; Sear, JW; Trafford, DJ1
Craib, IA; Dobb, GJ; Stewart, GO1
Howlett, JC; Jones, DM; Knight, JA; Samour, JH1
Bertuglia, S; Colantuoni, A; Intaglietta, M1
Holmes, GL; Kloczko, N; Weber, DA; Zimmerman, AW1
Sanders, RS; Sear, JW1
Descotes, J; Evreux, JC; Laschi-Locquerie, A; Tachon, P1
Cookson, JH; Mills, FJ1
Nakamura, S; Shigematsu, A; Takahashi, S; Tanaka, T1
Dyer, RG; Mansfield, S1
Ilkiw, JE; Middleton, DJ; Watson, AD1
Jackson, OF; Lawrence, K1
Blendl, M; Hoerster, W; Jungck, E; Klaucke, D; Klöss, T1
Descotes, J; Evreux, JC; Guillot, JP; Laschi-Loquerie, A; Tachon, P1
Blackler, P1
Eales, FA; Small, J1
Camburn, MA1
Waterman, AE1
Clark, WT; Colbourne, C; Cullen, LK; Goerke, MA; Nandapi, D; Swan, RA1
Benoit, E1
Allen, SL; Brammer, A; West, CD1
Bailey, TA; Samour, JH; Toosi, A1
Goodchild, CS; Nadeson, R1
Goodchild, CS; Nadeson, R; Tucker, AP; Winter, L1
Akk, G; Covey, DF; Evers, AS; Mennerick, S; Steinbach, JH; Zorumski, CF1
Hall, WJ; Markos, F; Ruane-O'Hora, T1

Reviews

1 review(s) available for alphaxalone and alphadolone

ArticleYear
The influence of the membrane on neurosteroid actions at GABA(A) receptors.
    Psychoneuroendocrinology, 2009, Volume: 34 Suppl 1

    Topics: Animals; Binding Sites; Fluorescent Dyes; GABA Antagonists; Membrane Potentials; Neurons; Neurotransmitter Agents; Pregnanediones; Receptors, GABA-A; Synaptic Membranes; Synaptic Transmission

2009

Trials

2 trial(s) available for alphaxalone and alphadolone

ArticleYear
Clinical trial of continuous infusion of alphaxalone/alphadolone in intensive care patients.
    Anaesthesia and intensive care, 1983, Volume: 11, Issue:2

    Topics: Adult; Aged; Anesthetics; Cholesterol; Clinical Trials as Topic; Drug Combinations; Electroencephalography; Female; Humans; Infusions, Parenteral; Intensive Care Units; Lipoproteins; Male; Middle Aged; Pregnanediones; Triglycerides

1983
Intra-patient comparison of the kinetics of alphaxalone and alphadolone in man.
    European journal of anaesthesiology, 1984, Volume: 1, Issue:2

    Topics: Aged; Anesthetics; Half-Life; Humans; Kinetics; Male; Middle Aged; Pregnanediones

1984

Other Studies

44 other study(ies) available for alphaxalone and alphadolone

ArticleYear
Pharmacological studies on the effects of althesin and its steroidal components on the cardiovascular system.
    The Journal of the Egyptian Medical Association, 1979, Volume: 62, Issue:1-2

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Blood Pressure; Bufo bufo; Cats; Electrocardiography; Pregnanediones; Rabbits; Rats

1979
Effects of althesin and its steroidal components on neuromuscular transmission and skeletal muscle.
    The Journal of the Egyptian Medical Association, 1979, Volume: 62, Issue:1-2

    Topics: Alfaxalone Alfadolone Mixture; Animals; Bufo bufo; Cats; Muscles; Neuromuscular Junction; Pregnanediones; Rats; Synaptic Transmission

1979
Pharmacological assessment of the anaesthetic potency and acute toxicity of althesin and its steroidal components in laboratory animals.
    The Journal of the Egyptian Medical Association, 1979, Volume: 62, Issue:1-2

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Female; Lethal Dose 50; Male; Mice; Pregnanediones

1979
Effects of althesin and its steroidal components on a variety of excised smooth muscle preparations.
    The Journal of the Egyptian Medical Association, 1979, Volume: 62, Issue:1-2

    Topics: Alfaxalone Alfadolone Mixture; Anesthesia, Intravenous; Animals; Guinea Pigs; Muscle, Smooth; Pregnanediones; Rabbits; Rats

1979
Effects of urethane, alphaxolone/alphadolone, or halothane with or without neuromuscular blockade on survival during repeated episodes of global cerebral ischaemia in the rat.
    Laboratory animals, 1992, Volume: 26, Issue:2

    Topics: Anesthetics; Animals; Arterial Occlusive Diseases; Brain Ischemia; Carotid Artery Diseases; Disease Models, Animal; Drug Combinations; Halothane; Male; Neuromuscular Blocking Agents; Pregnanediones; Rats; Rats, Inbred Strains; Respiration, Artificial; Retrospective Studies; Urethane

1992
Preparative surgery enhances the direct spinal actions of three injectable anaesthetics in the anaesthetized rat.
    Pain, 1991, Volume: 46, Issue:1

    Topics: Action Potentials; Anesthetics; Animals; Chloralose; Dose-Response Relationship, Drug; Ketamine; Male; Motor Neurons; Nociceptors; Physical Stimulation; Pregnanediones; Rats; Rats, Inbred Strains; Reflex; Spinal Cord; Surgical Procedures, Operative

1991
Effects of thiopentone, propofol, alphaxalone-alphadolone, ketamine and xylazine-ketamine on lower oesophageal sphincter pressure and barrier pressure in cats.
    The Veterinary record, 1991, Aug-17, Volume: 129, Issue:7

    Topics: Anesthetics; Animals; Cats; Esophagogastric Junction; Female; Ketamine; Male; Pregnanediones; Pressure; Propofol; Random Allocation; Stomach; Thiopental; Xylazine

1991
Inhibitory effects of steroidal anesthetics on histamine release from rat mast cells stimulated by concanavalin A, compound 48/80 and A23187.
    General pharmacology, 1988, Volume: 19, Issue:3

    Topics: Anesthetics; Animals; Calcimycin; Calcium; Concanavalin A; Drug Interactions; Histamine Release; In Vitro Techniques; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Pregnanediones; Rats; Rats, Inbred Strains; Receptors, Concanavalin A

1988
Respiratory obstruction after anaesthesia.
    The Veterinary record, 1989, Aug-19, Volume: 125, Issue:8

    Topics: Anesthetics; Animals; Cat Diseases; Cats; Drug Combinations; Female; Laryngeal Edema; Pregnanediones

1989
Anticonvulsant profile of an anesthetic steroid.
    Neuropharmacology, 1989, Volume: 28, Issue:8

    Topics: Anesthetics; Animals; Anticonvulsants; Electroshock; Male; Pentylenetetrazole; Postural Balance; Pregnanediones; Rats; Rats, Inbred Strains; Seizures; Steroids

1989
Remote intramuscular injection of immobilising drugs into fish using a laser-aimed underwater dart gun.
    The Veterinary record, 1988, Feb-20, Volume: 122, Issue:8

    Topics: Anesthetics; Animals; Fishes; Gallamine Triethiodide; Imidazoles; Immobilization; Injections, Intramuscular; Lasers; Pregnanediones

1988
Pressure reversal of alphaxalone/alphadolone and methohexitone in tadpoles: evidence for different molecular sites for general anaesthesia.
    British journal of pharmacology, 1986, Volume: 89, Issue:2

    Topics: Amphibians; Anesthesia, General; Anesthetics; Animals; Atmospheric Pressure; Carbon Dioxide; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Methohexital; Oxygen Consumption; Pregnanediones

1986
Alphaxolone-alphadolone for anesthesia of squirrel monkeys of different ages.
    Journal of medical primatology, 1988, Volume: 17, Issue:3

    Topics: Age Factors; Anesthesia; Anesthetics; Animals; Body Temperature; Cebidae; Dose-Response Relationship, Drug; Female; Injections, Intramuscular; Male; Pregnanediones; Reference Values; Respiration; Saimiri

1988
The effects of different anesthetics on blood steroid concentrations in domestic tom-cats.
    Australian veterinary journal, 1988, Volume: 65, Issue:12

    Topics: Androstenedione; Anesthesia, Intravenous; Anesthetics; Animals; Animals, Domestic; Cats; Ketamine; Male; Pregnanediones; Testosterone; Thiopental; Time Factors; Xylazine

1988
Anaesthesia with alphaxalone plus alphadolone acetate decreases serum concentrations of LH in castrated rats.
    The Journal of endocrinology, 1987, Volume: 115, Issue:2

    Topics: Anesthetics; Animals; Depression, Chemical; Ketamine; Luteinizing Hormone; Male; Orchiectomy; Pregnanediones; Rats; Rats, Inbred Strains; Urethane

1987
An anaesthetic combination of ketamine, xylazine and alphaxalone-alphadolone in ostriches (Struthio camelus).
    The Veterinary record, 1986, Jun-28, Volume: 118, Issue:26

    Topics: Anesthesia, Intravenous; Animals; Birds; Dose-Response Relationship, Drug; Ketamine; Pregnanediones; Thiazines; Xylazine

1986
[Prolonged cerebral electrical "silence" with intracranial pressure monitored by extradural approach in the treatment of post-traumatic coma using thiopentone combined with alphaxalone-alphadolone. Clinical case].
    Minerva anestesiologica, 1985, Volume: 51, Issue:10

    Topics: Adolescent; Anesthetics; Brain; Brain Injuries; Coma; Drug Therapy, Combination; Electroencephalography; Humans; Intracranial Pressure; Male; Monitoring, Physiologic; Pregnanediones; Thiopental

1985
The effects of anaesthetics and remote noxious stimuli on the jaw-opening reflex evoked by tooth-pulp stimulation in the cat.
    Brain research, 1985, Feb-18, Volume: 327, Issue:1-2

    Topics: Anesthetics; Animals; Cats; Dental Pulp; Electric Stimulation; Female; Jaw; Male; Methohexital; Pain; Physical Stimulation; Pregnanediones; Reflex

1985
Cardiac performance of isolated beating hearts obtained from rats anesthetized by three different agents.
    Laboratory animal science, 1985, Volume: 35, Issue:2

    Topics: Anesthesia; Animals; Coronary Circulation; Ether; Ethyl Ethers; Heart; Heart Rate; Pentobarbital; Pregnanediones; Rats

1985
Allergic reactions to intravenous anaesthetic induction agents and muscle relaxants. Case reports and a clinical review.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1985, Jun-22, Volume: 67, Issue:25

    Topics: Alcuronium; Anesthesia, Intravenous; Anesthetics; Child; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Pregnanediones; Toxiferine

1985
[Comparative studies of short-term anesthesia with alfentanil/etomidate and alphaxalone/alphadolone in cats].
    Tierarztliche Praxis. Supplement, 1985, Volume: 1

    Topics: Adjuvants, Anesthesia; Alfentanil; Anesthesia, Intravenous; Anesthetics; Animals; Cats; Etomidate; Fentanyl; Heart Rate; Imidazoles; Pregnanediones; Reflex; Respiration

1985
The in vivo metabolism of Althesin (alphaxalone + alphadolone acetate) in man.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:7

    Topics: Adult; Aged; Alfaxalone Alfadolone Mixture; Bile; Biotransformation; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Pregnanediones; Time Factors

1981
Comparative studies of the use of some injectable anaesthetic agents in birds.
    The Veterinary record, 1984, Jul-07, Volume: 115, Issue:1

    Topics: Anesthesia; Anesthetics; Animals; Animals, Zoo; Birds; Drug Combinations; Female; Immobilization; Injections, Intramuscular; Injections, Intravenous; Ketamine; Male; Pregnanediones; Xylazine

1984
Effects of anesthesia on the spontaneous activity of the microvasculature.
    International journal of microcirculation, clinical and experimental, 1984, Volume: 3, Issue:1

    Topics: Anesthetics; Animals; Arteries; Chloralose; Cricetinae; Ether; Mesocricetus; Microcirculation; Pentobarbital; Pregnanediones; Urethane; Vasodilation; Vasomotor System; Veins; Venules

1984
Relationship of endocrine function to inhibition of kindling.
    Brain research, 1984, Volume: 318, Issue:1

    Topics: Aging; Amygdala; Anesthetics; Animals; Kindling, Neurologic; Male; Pregnanediones; Progesterone; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1984
Adjuvancy of Cremophor Elo in rodents.
    International archives of allergy and applied immunology, 1983, Volume: 72, Issue:3

    Topics: Adjuvants, Immunologic; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Hypersensitivity, Delayed; Male; Mice; Pregnanediones; Serum Albumin, Bovine

1983
Continuous infusion anaesthesia in baboons with alphaxolone-alphadolone.
    Laboratory animals, 1983, Volume: 17, Issue:3

    Topics: Anesthesia; Animals; Animals, Laboratory; Infusions, Parenteral; Papio; Pregnanediones

1983
Spectral studies on the effect of a new steroidal anesthetic agent alphadione on rat hepatic microsomes.
    Journal of UOEH, 1983, Sep-01, Volume: 5, Issue:3

    Topics: Anesthetics; Animals; Cytochrome P-450 Enzyme System; Drug Combinations; Inactivation, Metabolic; Male; Microsomes, Liver; Pregnanediones; Rats; Rats, Inbred Strains; Spectrophotometry; Substrate Specificity

1983
Anaesthesia with alphaxalone plus alphadolone acetate blocks the oestrogen-stimulated LH surge and impairs pulsatile LH secretion in ovariectomized female rats.
    The Journal of endocrinology, 1984, Volume: 102, Issue:1

    Topics: Anesthetics; Animals; Castration; Estradiol; Female; Luteinizing Hormone; Pregnanediones; Rats; Rats, Inbred Strains; Secretory Rate

1984
Physiological effects of thiopentone, ketamine and CT 1341 in cats.
    Research in veterinary science, 1982, Volume: 32, Issue:2

    Topics: Anesthetics; Animals; Blood Pressure; Carbon Dioxide; Cats; Heart Rate; Ketamine; Oxygen; Pregnanediones; Respiration; Thiopental

1982
Alphaxalone/alphadolone anaesthesia in reptiles.
    The Veterinary record, 1983, Jan-08, Volume: 112, Issue:2

    Topics: Anesthesia; Anesthetics; Animals; Pregnanediones; Reptiles; Surgery, Veterinary

1983
[Experiences with the steroid narcotic alfaxalone/alfadolone (Aurantex) in emergency patients in rescue service].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1983, Volume: 18, Issue:1

    Topics: Adult; Anesthetics; Blood Pressure; Drug Combinations; Emergencies; Female; Heart Rate; Humans; Intubation; Male; Pregnanediones; Transportation of Patients; Wounds and Injuries

1983
Assessment of the allergenic potential of althesin and its constituents.
    British journal of anaesthesia, 1983, Volume: 55, Issue:8

    Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Drug Hypersensitivity; Female; Glycerol; Guinea Pigs; Intradermal Tests; Male; Pregnanediones

1983
Adverse reaction in cat anaesthetic.
    The Veterinary record, 1982, Feb-27, Volume: 110, Issue:9

    Topics: Anesthetics; Animals; Cats; Drug Combinations; Pregnanediones

1982
Alphaxalone/alphadolone anaesthesia in the lamb.
    The Veterinary record, 1982, Mar-20, Volume: 110, Issue:12

    Topics: Anesthesia; Anesthetics; Animals; Animals, Newborn; Drug Combinations; Heart Rate; Pregnanediones; Respiration; Sheep

1982
Use of alphaxalone-alphadolone in ruminants.
    The Veterinary record, 1982, Aug-21, Volume: 111, Issue:8

    Topics: Anesthesia; Animals; Cattle; Drug Combinations; Goats; Injections, Intravenous; Pregnanediones; Rumen; Sheep

1982
Evaluation of the actions and use of alphaxolone/alphadolone (CT1341) in sheep.
    Research in veterinary science, 1981, Volume: 30, Issue:1

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Pregnanediones; Sheep

1981
Ostrich anaesthesia: xylazine premedication followed by alphaxalone/alphadolone and isoflurane.
    Australian veterinary journal, 1995, Volume: 72, Issue:4

    Topics: Anesthesia; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Birds; Drug Therapy, Combination; Isoflurane; Preanesthetic Medication; Pregnanediones; Xylazine

1995
Effects of intravenous anaesthetics on nerve axons.
    European journal of anaesthesiology, 1995, Volume: 12, Issue:1

    Topics: Action Potentials; Anesthetics, Intravenous; Animals; Axons; Dose-Response Relationship, Drug; Etomidate; Ion Channel Gating; Ketamine; Membrane Potentials; Nerve Fibers, Myelinated; Potassium; Potassium Channels; Pregnanediones; Rana esculenta; Sodium; Sodium Channels; Time Factors

1995
A comparison of propofol with other injectable anaesthetics in a rat model for measuring cardiovascular parameters.
    Laboratory animals, 1993, Volume: 27, Issue:3

    Topics: Anesthesia, Intravenous; Anesthetics; Animals; Blood Pressure; Butyrophenones; Female; Fentanyl; Heart Rate; Male; Midazolam; Pentobarbital; Pregnanediones; Propofol; Rats; Respiration; Thiopental

1993
Anaesthesia of cranes with alphaxolone-alphadolone.
    The Veterinary record, 1999, Jul-17, Volume: 145, Issue:3

    Topics: Anesthesia Recovery Period; Anesthesia, Intravenous; Anesthetics, Combined; Animals; Birds; Female; Male; Pregnanediones

1999
Antinociceptive properties of neurosteroids II. Experiments with Saffan and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the involvement of spinal cord GABA(A) receptors.
    Pain, 2000, Volume: 88, Issue:1

    Topics: Alfaxalone Alfadolone Mixture; Anesthetics; Animals; Bicuculline; GABA Antagonists; GABA-A Receptor Antagonists; Male; Nociceptors; Pain Measurement; Pregnanediones; Pyridazines; Rats; Rats, Wistar; Receptors, GABA-A; Reference Values; Spinal Cord; Steroids; Time Factors

2000
Antinociceptive properties of neurosteroids: a comparison of alphadolone and alphaxalone in potentiation of opioid antinociception.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:3

    Topics: Analgesics, Opioid; Anesthetics; Animals; Consciousness; Dose-Response Relationship, Drug; Drug Synergism; Injections, Intraperitoneal; Male; Motor Activity; Pain Measurement; Pain Threshold; Postural Balance; Pregnanediones; Rats

2003
The effect of alphaxalone-alphadolone, propofol, and pentobarbitone anaesthesia on the β-endorphin and ACTH response to haemorrhage in the pig.
    Canadian journal of physiology and pharmacology, 2011, Volume: 89, Issue:7

    Topics: Adrenocorticotropic Hormone; Anesthesia; Anesthetics; Animals; beta-Endorphin; Blood Pressure; Heart Rate; Hemorrhage; Hypovolemia; Pentobarbital; Pregnanediones; Propofol; Swine

2011