Page last updated: 2024-09-03

alphaprodine and spiperone

alphaprodine has been researched along with spiperone in 2 studies

Compound Research Comparison

Studies
(alphaprodine)
Trials
(alphaprodine)
Recent Studies (post-2010)
(alphaprodine)
Studies
(spiperone)
Trials
(spiperone)
Recent Studies (post-2010) (spiperone)
163202,9441385

Protein Interaction Comparison

ProteinTaxonomyalphaprodine (IC50)spiperone (IC50)
Bile salt export pumpHomo sapiens (human)10
D(2) dopamine receptorHomo sapiens (human)0.0008
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.097
D(4) dopamine receptorHomo sapiens (human)0.0005
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.097
Histamine H1 receptorCavia porcellus (domestic guinea pig)0.097
D(3) dopamine receptorHomo sapiens (human)0.0635
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.097
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0001
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.955

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aceto, MD; Bowman, ER; Frigeni, V; Harris, LS; Iorio, MA; May, EL1
Frigeni, V; Iorio, MA; Reymer, TP1

Other Studies

2 other study(ies) available for alphaprodine and spiperone

ArticleYear
Common stereospecificity of opioid and dopamine systems for N-butyrophenone prodine-like compounds.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:1

    Topics: Alphaprodine; Analgesia; Analgesics; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Brain; Dihydromorphine; Indicators and Reagents; Isomerism; Male; Mice; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Opioid; Receptors, Opioid, mu; Spiperone; Stereotyped Behavior; Structure-Activity Relationship

1991
Combined analgesic/neuroleptic activity in N-butyrophenone prodine-like compounds.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Adenylyl Cyclase Inhibitors; Alphaprodine; Analgesics; Animals; Antipsychotic Agents; Apomorphine; Butyrophenones; Dihydromorphine; Mice; Spiperone; Stereotyped Behavior

1987