Compounds > alphaprodine

Page last updated: 2024-09-03

alphaprodine and morphine

alphaprodine has been researched along with morphine in 19 studies

Compound Research Comparison

Studies (alphaprodine)	Trials (alphaprodine)	Recent Studies (post-2010) (alphaprodine)	Studies (morphine)	Trials (morphine)	Recent Studies (post-2010) (morphine)
163	2	0	44,270	5,200	8,695

Protein Interaction Comparison

Protein	Taxonomy	alphaprodine (IC50)	morphine (IC50)
Delta-type opioid receptor	Mus musculus (house mouse)		0.2939
Delta-type opioid receptor	Rattus norvegicus (Norway rat)		0.2278
Kappa-type opioid receptor	Mus musculus (house mouse)		0.0828
Mu-type opioid receptor	Rattus norvegicus (Norway rat)		0.0385
Kappa-type opioid receptor	Rattus norvegicus (Norway rat)		0.0545
Mu-type opioid receptor	Homo sapiens (human)		0.122
Delta-type opioid receptor	Homo sapiens (human)		0.1199
Kappa-type opioid receptor	Cavia porcellus (domestic guinea pig)		0.9308
Kappa-type opioid receptor	Homo sapiens (human)		0.655
Mu-type opioid receptor	Mus musculus (house mouse)		0.3305
Mu-type opioid receptor	Cavia porcellus (domestic guinea pig)		0.202
Beta-2 adrenergic receptor	Cavia porcellus (domestic guinea pig)		0.25

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	19 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Leander, JD	2
McDonald, JS	1
Hon, EH; Miller, FC; Paul, RH; Petrie, RH; Sacks, DA; Sugarman, R; Wu, R	1
Jester, JR; Loew, GH	1
Gorodetzky, CW	1
Röthig, J	1
Foldes, FF	1
Scanlon, JW	1
Gomaa, ZS; Larson, DL; Portoghese, PS	1
Ahtee, L; Saarnivaara, L	1
Brown, JH; Garrett, RL	1
Bellville, JW; Forrest, WH	1
Bovill, JG; Sebel, PS; Stanley, TH	1
EGGE, RK; ORKIN, LR; ROVENSTINE, EA	1
ARTUSIO, JF; MAZZIA, VD; VAN POZNAK, A	1
BACKNER, DD; FOLDES, FF; GORDON, EH	1
KUCK, MA; ROBERTS, H	1
LEE, RE; PFEIFFER, CC	1

Reviews

4 review(s) available for alphaprodine and morphine

Article	Year
[Analgesics. 32]. Pharmazeutische Praxis, 1969, Volume: 5 Topics: Alphaprodine; Analgesics; Azepines; Benzimidazoles; Bridged-Ring Compounds; Codeine; Cyclazocine; Dextromoramide; Dextropropoxyphene; Fentanyl; Heroin; Humans; Hydromorphone; Isonipecotic Acids; Levallorphan; Levorphanol; Lysergic Acid Diethylamide; Methadone; Morphinans; Morphine; Nalorphine; Naphthoquinones; Oxymorphone; Pentazocine; Phenazocine; Phenoperidine	1969
Neuroleptanesthesia for general surgery. International anesthesiology clinics, 1973,Fall, Volume: 11, Issue:3 Topics: Alphaprodine; Anesthesia, Inhalation; Diphenhydramine; Droperidol; Female; Fentanyl; Humans; Hypertension; Hypotension; Injections, Intravenous; Male; Meperidine; Middle Aged; Morphine; Neuroleptanalgesia; Neuromuscular Nondepolarizing Agents; Nitrous Oxide; Preanesthetic Medication; Respiration; Respiration, Artificial; Respiratory Insufficiency; Scopolamine; Surgical Procedures, Operative	1973
Obstetric anesthesia as a neonatal risk factor in normal labor and delivery. Clinics in perinatology, 1974, Volume: 1, Issue:2 Topics: Alphaprodine; Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Barbiturates; Belladonna Alkaloids; Benzodiazepines; Child Behavior; Female; Fetus; Humans; Infant, Newborn; Ketamine; Maternal-Fetal Exchange; Meperidine; Morphine; Narcotic Antagonists; Pentazocine; Phenothiazines; Pregnancy; Risk	1974
Opioid analgesics in anesthesia: with special reference to their use in cardiovascular anesthesia. Anesthesiology, 1984, Volume: 61, Issue:6 Topics: Alfentanil; Alphaprodine; Analgesics, Opioid; Anesthesia, General; Animals; Awareness; Brain; Cardiac Surgical Procedures; Fentanyl; Hemodynamics; Hormones; Humans; Meperidine; Morphine; Muscle Rigidity; Neuroleptanalgesia; Neuromuscular Junction; Respiration Disorders; Stress, Physiological; Sufentanil; Vascular Surgical Procedures	1984

Other Studies

15 other study(ies) available for alphaprodine and morphine

Article	Year
Comparing the effects of anileridine, alphaprodine and fentanyl on schedule-controlled responding by pigeons. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:3 Topics: Alphaprodine; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Fentanyl; Isonipecotic Acids; Male; Methadone; Morphine; Naloxone; Reinforcement Schedule	1978
Preanesthetic and intrapartal medications. Clinical obstetrics and gynecology, 1977, Volume: 20, Issue:2 Topics: Alphaprodine; Anesthetics; Anesthetics, Local; Animals; Barbiturates; Benzodiazepines; Bupivacaine; Chemical Phenomena; Chemistry; Ethanol; Female; Fetus; Humans; Infant, Newborn; Labor, Obstetric; Lidocaine; Maternal-Fetal Exchange; Meperidine; Mepivacaine; Morphine; Preanesthetic Medication; Pregnancy; Procaine; Promethazine; Psychology; Scopolamine; Tetracaine	1977
The effect of drugs on uterine activity. Obstetrics and gynecology, 1976, Volume: 48, Issue:4 Topics: Adolescent; Adult; Alphaprodine; Female; Humans; Hydroxyzine; Labor, Obstetric; Magnesium Sulfate; Meperidine; Morphine; Narcotics; Pregnancy; Pressure; Promethazine; Uterine Contraction; Uterus	1976
Quantum chemical studies of meperidine and prodine. Journal of medicinal chemistry, 1975, Volume: 18, Issue:11 Topics: Alphaprodine; Chemical Phenomena; Chemistry; Crystallography; Meperidine; Models, Molecular; Molecular Conformation; Morphine; Piperidines; Quantum Theory; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship	1975
Sensitivity of thin-layer chromatography for detection of 16 opioids, cocaine and quinine. Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3 Topics: Alphaprodine; Chromatography, Thin Layer; Cocaine; Codeine; Cyclazocine; Dextropropoxyphene; Humans; Hydromorphone; Levallorphan; Levorphanol; Meperidine; Methadone; Methods; Morphinans; Morphine; Nalorphine; Naloxone; Oxymorphone; Pentazocine; Quinine	1972
Stereochemical studies on medicinal agents. 13. Correlation of the solid-state conformations of 1,3,5-trimethyl- and 1,3-dimethyl-4-phenyl-4-propionoxypiperidine enantiomers with their absolute stereoselectivity at analgetic receptors. Journal of medicinal chemistry, 1973, Volume: 16, Issue:3 Topics: Alphaprodine; Analgesics; Animals; Crystallography; Dose-Response Relationship, Drug; Magnetic Resonance Spectroscopy; Male; Methylation; Mice; Models, Structural; Molecular Conformation; Morphine; Optical Rotation; Reaction Time; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship	1973
The effect of narcotic analgesics on the uptake of 5-hydroxytryptamine and (-)-metaraminol by blood platelets. British journal of pharmacology, 1973, Volume: 47, Issue:4 Topics: Alphaprodine; Animals; Blood Platelets; Cyclazocine; Dextropropoxyphene; Humans; In Vitro Techniques; Isonipecotic Acids; Metaraminol; Methadone; Morphine; Nalorphine; Narcotics; Pentazocine; Rabbits; Serotonin; Serotonin Antagonists; Spectrometry, Fluorescence; Tritium	1973
Inhibition of constriction-induced reactive hyperemic edema. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 139, Issue:2 Topics: Alphaprodine; Animals; Atropine; Constriction; Edema; Epinephrine; Hexamethonium Compounds; Hindlimb; Hyperemia; Isoproterenol; Male; Meperidine; Methysergide; Morphine; Norepinephrine; Phenothiazines; Phentolamine; Phenylephrine; Rats; Sotalol; Tripelennamine; Vasoconstrictor Agents	1972
Respiratory effects of alphaprodine in man. Obstetrics and gynecology, 1968, Volume: 31, Issue:1 Topics: Alphaprodine; Humans; Male; Morphine; Respiration; Respiratory Function Tests	1968
Comparison of morphine, meperidine, anileridine, and alphaprodine on schedule-controlled responding and analgesia. Pharmacology, biochemistry, and behavior, 1980, Volume: 12, Issue:5 Topics: Alphaprodine; Analgesics, Opioid; Animals; Behavior, Animal; Conditioning, Operant; Isonipecotic Acids; Male; Meperidine; Morphine; Naloxone; Rats; Reaction Time; Reinforcement Schedule	1980
Effect of nisentil, meperidine and morphine on respiration in man. Anesthesiology, 1955, Volume: 16, Issue:5 Topics: Alphaprodine; Analgesics; Meperidine; Morphine; Respiration	1955
Cortical effect of alphaprodine and of chlorpromazine during thiopental narcosis. Journal of the American Medical Association, 1957, May-18, Volume: 164, Issue:3 Topics: Alphaprodine; Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Chlorpromazine; Electroencephalography; Humans; Morphine; Pain Management; Stupor; Thiopental	1957
The combined use of alphaprodine (nisentil) hydrochloride and levallorphan (lorfan) tartrate for analgesia in obstetrics. American journal of obstetrics and gynecology, 1957, Volume: 74, Issue:2 Topics: Alphaprodine; Analgesia; Analgesics; Anesthesia; Anesthesia and Analgesia; Female; Humans; Labor, Obstetric; Levallorphan; Morphine; Obstetrics; Pain Management; Pregnancy; Tartrates	1957
Use of alphaprodine and levallorphan during labour. Canadian Medical Association journal, 1960, Nov-19, Volume: 83 Topics: Alphaprodine; Analgesics; Analgesics, Non-Narcotic; Anesthesia; Anesthesia, Obstetrical; Antipyretics; Female; Humans; Labor, Obstetric; Levallorphan; Morphine; Pregnancy	1960
Influence of analgesics, dromoran, nisentil and morphine, on pain thresholds in man. Journal of applied physiology, 1951, Volume: 4, Issue:3 Topics: Alphaprodine; Analgesics; Humans; Leadership; Male; Morphine; Pain; Pain Threshold	1951