alpha-naphthoflavone has been researched along with warfarin in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CH; De Clercq, E; Feng, D; Ginex, T; Kang, D; Lee, KH; Liu, X; Luque, FJ; Murugan, NA; Pannecouque, C; Steitz, TA; Wang, Z; Wei, F; Wu, G; Yang, Y; Zhan, P; Zhang, H; Zhang, J; Zhao, T | 1 |
| Diehl, H; Schröder, U | 1 |
| Burke, MD; Mayer, RT; Rawlins, MD; Rettie, AE; Williams, FM | 1 |
| Finnen, MJ; Shuster, S | 1 |
| Borm, PJ; Frankhuijzen-Sierevogel, A; Noordhoek, J | 1 |
| Grafstöm, R; Stohs, SJ | 1 |
| Ekins, S; Ring, BJ; VandenBranden, M; Wrighton, SA | 1 |
| Beaune, P; Brazier, JL; Buronfosse, T; Désage, M; Guitton, J; Lepape, A | 1 |
| Gorski, JC; Hall, SD; Hamman, MA; Jones, DR; Wrighton, SA | 1 |
| Ahn, HJ; Cho, US; Dong, MS; Kim, KH; Park, EY | 1 |
| Cho, US; Dong, MS; Kim, K; Kim, KH; Park, BS; Park, EY | 1 |
| Davydov, DR; Davydova, NY; Halpert, JR; Tsalkova, TN | 1 |
| Chuang, MC; Huang, CC; Lin, CH; Lin, P; Lin, PH | 1 |
| Boobis, AR; Brodie, MJ; Davies, DS; Kahn, GC; Whyte, C | 1 |
| Ahinko, M; Huuskonen, J; Juvonen, RO; Pentikäinen, OT; Raunio, H | 1 |
| Javaid, A; Jokinen, EM; Juvonen, RO; Lehtonen, M; Pentikäinen, OT; Raunio, H | 1 |
16 other study(ies) available for alpha-naphthoflavone and warfarin
| Article | Year |
|---|---|
Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.
Topics: Animals; Anti-HIV Agents; Binding Sites; Cell Line, Tumor; Furans; HIV Reverse Transcriptase; HIV-1; Humans; Male; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Molecular Structure; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2019 |
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine | 1987 |
Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers.
Topics: Animals; Benzoflavones; Coumarins; Female; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes; Microsomes, Liver; Oxazines; Skin; Structure-Activity Relationship | 1986 |
Phase 1 and Phase 2 drug metabolism in isolated epidermal cells from adult hairless mice and in whole human hair follicles.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Epidermis; Female; Hair; Humans; Kinetics; Male; Mice; Mice, Hairless; Proadifen; Spectrometry, Fluorescence; Umbelliferones | 1985 |
Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes. The effect of induction with 3-methylcholanthrene and inhibition with alpha-naphthoflavone.
Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Flavonoids; Humans; Intestinal Mucosa; Kinetics; Male; Methylcholanthrene; Mice; Microsomes; Phenacetin; Rats; Rats, Inbred Strains | 1983 |
Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells.
Topics: Animals; Benzoflavones; Benzopyrenes; Coumarins; Cytochrome P-450 CYP1A1; Female; Intestine, Small; Methylcholanthrene; Metyrapone; Microsomes; Oxidoreductases; Proadifen; Rats; Rats, Inbred Strains; Rotenone | 1981 |
Examination of purported probes of human CYP2B6.
Topics: Aryl Hydrocarbon Hydroxylases; B-Lymphocytes; Benzoflavones; Blotting, Western; Cell Line; Chloramphenicol; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 CYP2B6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Humans; In Vitro Techniques; Kinetics; Microsomes; Microsomes, Liver; Molecular Probes; Orphenadrine; Oxidoreductases, N-Demethylating; Substrate Specificity | 1997 |
Possible involvement of multiple cytochrome P450S in fentanyl and sufentanil metabolism as opposed to alfentanil.
Topics: Alfentanil; Benzoflavones; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Fentanyl; Humans; Immunoblotting; Isoenzymes; Microsomes, Liver; Saccharomyces cerevisiae; Sufentanil; Transfection | 1997 |
Biotransformation of alprazolam by members of the human cytochrome P4503A subfamily.
Topics: Alprazolam; Aryl Hydrocarbon Hydroxylases; B-Lymphocytes; Benzoflavones; Biotransformation; Coumarins; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Humans; Hypnotics and Sedatives; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Quinidine; Recombinant Proteins; Sulfaphenazole; Troleandomycin | 1999 |
Influence of ligand binding to human cytochrome P-450 1A2: conformational activation and stabilization by alpha-naphthoflavone.
Topics: Benzoflavones; Chromatography, Ion Exchange; Coumarins; Cytochrome P-450 CYP1A2; Detergents; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Stability; Humans; Ligands; Protein Binding; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence | 2001 |
Tight-binding inhibition by alpha-naphthoflavone of human cytochrome P450 1A2.
Topics: Amino Acid Sequence; Benzoflavones; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Humans; Kinetics; Molecular Sequence Data; Oxazines; Sequence Alignment; Substrate Specificity | 2003 |
Mechanism of interactions of alpha-naphthoflavone with cytochrome P450 3A4 explored with an engineered enzyme bearing a fluorescent probe.
Topics: 2-Naphthylamine; Amino Acid Substitution; Benzoflavones; Binding Sites; Coumarins; Cysteine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Kinetics; Models, Molecular; Substrate Specificity; Time Factors | 2007 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
Topics: Benzamides; Benzoflavones; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Survival; Coumarins; DNA Breaks; Environmental Pollutants; Estrogen Receptor alpha; Glutathione; Humans; NAD; NADP; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Dibenzodioxins; Reactive Oxygen Species; Receptors, Aryl Hydrocarbon; Tamoxifen | 2007 |
Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Coumarins; Cytochrome P-450 Enzyme System; Humans; Kinetics; Male; Metyrapone; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Subcellular Fractions; Substrate Specificity | 1981 |
Development of new Coumarin-based profluorescent substrates for human cytochrome P450 enzymes.
Topics: Benzoflavones; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluorescence; Humans; Inactivation, Metabolic; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Docking Simulation; Oxidation-Reduction | 2019 |
Inhibition of human CYP1 enzymes by a classical inhibitor α-naphthoflavone and a novel inhibitor N-(3, 5-dichlorophenyl)cyclopropanecarboxamide: An in vitro and in silico study.
Topics: Amides; Benzoflavones; Binding Sites; Catalytic Domain; Coumarins; Cyclopropanes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 1; Humans; Liver; Molecular Dynamics Simulation; Oxidation-Reduction | 2020 |