Page last updated: 2024-08-21

alpha-naphthoflavone and theophylline

alpha-naphthoflavone has been researched along with theophylline in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aubé, J; Chu, YK; Chung, D; Golden, JE; Guo, H; Jonsson, CB; McKellip, S; Noah, JW; Rasmussen, L; Roy, S; Schroeder, CE; Smith, LH; Smith, RA; Sosa, M; Sotsky, J; Tower, NA; White, EL; Yao, T1
Lennard, MS; Loft, S; Otton, SV; Poulsen, HE; Tucker, GT1
Birkett, DJ; Matthews, AP; McManus, ME; Meller, D; Miners, JO; Robson, RA; Stupans, I1
Gelboin, HV; Goldfarb, IS; Tsyrlov, IB1
Bachmann, K; Loch, J; Potter, J; Sanyal, G; Schiavone, R1
Satake, N; Shibata, S1
Bu, HZ; Knuth, K; Magis, L; Teitelbaum, P1
Fernandez, M; Hashemi, E; Ioannides, C; Lewis, DF; Papagiannidou, E; Skene, DJ; Snelling, J1
Audus, KL; Avery, ML; Meek, CE1
Abolfathi, Z; Beaune, P; Labbé, L; Lessard, E; Pakdel, H; Turgeon, J1
Adcock, JM; Daniels, JS; Locuson, CW; Williams, P1

Other Studies

11 other study(ies) available for alpha-naphthoflavone and theophylline

ArticleYear
Development of (E)-2-((1,4-dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-amidinophenylbenzamides as potent inhibitors of venezuelan equine encephalitis virus.
    Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20

    Topics: Animals; Antiviral Agents; Benzamides; Drug Evaluation, Preclinical; Encephalitis Virus, Venezuelan Equine; Encephalomyelitis, Venezuelan Equine; Heterocyclic Compounds, 2-Ring; Mice, Inbred C3H; Mice, Inbred C57BL; Piperazines; Quinazolinones; Small Molecule Libraries; Structure-Activity Relationship; Virus Replication

2014
Characterization of metronidazole metabolism by human liver microsomes.
    Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8

    Topics: Acetone; Adult; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mephenytoin; Metronidazole; Microsomes, Liver; Middle Aged; Nifedipine; Phenacetin; Quinidine; Theophylline; Tolbutamide

1991
Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies.
    Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9

    Topics: Adult; Benzoflavones; Caffeine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Humans; Immunologic Techniques; In Vitro Techniques; Isoenzymes; Kinetics; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Verapamil

1988
Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.
    Archives of biochemistry and biophysics, 1993, Volume: 307, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Benzoflavones; Cell Line; Cloning, Molecular; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Isoenzymes; Mice; Microsomes, Liver; Multigene Family; Oxidoreductases; Recombinant Proteins; Theophylline; Vaccinia virus

1993
In vivo evidence that theophylline is metabolized principally by CYP1A in rats.
    Pharmacology, 1993, Volume: 47, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Male; Oxidoreductases; Rats; Rats, Sprague-Dawley; Theophylline

1993
The potentiating effect of genistein on the relaxation induced by isoproterenol in rat aortic rings.
    General pharmacology, 1999, Volume: 33, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Aorta; Benzoflavones; Bucladesine; Colforsin; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoproterenol; Male; Methoxsalen; Muscle Relaxation; Phosphodiesterase Inhibitors; Quinacrine; Rats; Rats, Wistar; Theophylline

1999
High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. V. Validation of a direct injection/on-line guard cartridge extraction--tandem mass spectrometry method for CYP1A2 inhibition assessment.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2001, Volume: 12, Issue:4

    Topics: Benzoflavones; Biological Assay; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Humans; Mass Spectrometry; Microsomes, Liver; Oxazines; Theophylline

2001
Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Animals; Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Melatonin; Microsomes, Liver; Models, Molecular; NADP; Oxidation-Reduction; Rats; Rats, Wistar; Theophylline

2001
The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.
    Placenta, 2003, Volume: 24, Issue:1

    Topics: Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Methylcholanthrene; Microsomes, Liver; Smoking; Theophylline; Trophoblasts; Tumor Cells, Cultured

2003
Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:1

    Topics: Anti-Arrhythmia Agents; Benzoflavones; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Hydroxylation; Kinetics; Mexiletine; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Saccharomyces cerevisiae; Theophylline

2003
Evaluation of tizanidine as a marker of canine CYP1A2 activity.
    Journal of veterinary pharmacology and therapeutics, 2016, Volume: 39, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Benzoflavones; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dogs; Enrofloxacin; Female; Fluoroquinolones; Microsomes, Liver; Molecular Probes; Phenacetin; Substrate Specificity; Theophylline

2016