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alpha-naphthoflavone and phenobarbital

alpha-naphthoflavone has been researched along with phenobarbital in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199030 (66.67)18.7374
1990's12 (26.67)18.2507
2000's3 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Hirobe, M; Ohi, H; Ohta, S; Takahara, E1
Burnett, AK; Craft, JA; Lambard, SE; Wolf, CR1
Giri, SN; Siegel, DM1
Braselton, WE; Chen, TH; Kuslikis, BI1
Blaich, G; Cikryt, P; Göttlicher, M; Metzler, M1
Blaich, G; Metzler, M; Raabe, H1
Guengerich, FP; Shimada, T; Shimura, H; Tanaka, R; Yamazaki, H1
Crouch, LS; Ebel, RE1
Gerber, N; Hilliard, JB; Mays, DC; Wong, DD1
Blumer, JL; Frank, DM1
Bender, PE; Eckardt, RD; Leonard, TB; Newton, JF; Romano, MC; Straub, KM1
Koda, A; Konishi, Y; Mori, Y; Nagai, H; Toyoshi, K; Yamazaki, H1
Emi, Y; Omura, T1
Gessner, T; Olson, JR; Wroblewski, VJ1
De Angelis, G; Funari, E; Testai, E; Verdina, A; Vittozzi, L1
Boobis, AR; Davies, DS; Whyte, C1
Andries, M; Lucier, GW; Lundgren, K; Thompson, C1
Flory, W; Henk, WG; Turk, MA1
Forsberg, JG; Hillbertz-Nilsson, K1
Kuwahara, S; Mannering, GJ1
Haaf, H; Metzler, M1
Miyauchi, M1
Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A1
Goldstein, JA; Huckins, JN; Linko, P; Stalling, DL1
Nagata, K; Yoshihara, S; Yoshimura, H1
Gielen, JE; Kremers, P; Pasleau, F1
Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT1
Clark, JD; Hatch, RC; Jain, AV; Mahaffey, EA; Weiss, R1
DePierre, JW; Meijer, J1
Bryant, BJ; Easterling, R; Nesnow, S; Rudo, K1
Highet, RJ; Jerina, DM; Levin, W; Ryan, DE; Shibata, T; Thomas, PE; Vyas, KP; Yeh, HJ1
Nesnow, S1
Aune, T; Dybing, E; Nelson, SD1
Coombs, MM1
Hiraga, K; Kawano, S; Kojima, A1
Bergman, H; Nesnow, S1
Felton, JS; Jensen, NM; Levitt, RC; Nebert, DW1
Barrenscheen, M; Doehmer, J; Glatt, HR; Goeptar, AR; Groot, EJ; Seidel, A; te Koppele, JM; Vermeulen, NP; Wölfel, C1
Kupfer, D; Lee, CA; Mani, C; Rifkind, AB1
Apostolides, Z; Balentine, DA; Hara, Y; Harbowy, ME; Weisburger, JH1
Dhawan, A; Parmar, D; Seth, PK1
Melancon, MJ; Renauld, AE; Sordillo, LM1
Dusatti, F; Ferro, M; Gelardi, A; Morini, F; Penco, S1
Jemnitz, K; Török, G; Tóth, E; Vereczkey, L; Veres, Z1

Reviews

1 review(s) available for alpha-naphthoflavone and phenobarbital

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

44 other study(ies) available for alpha-naphthoflavone and phenobarbital

ArticleYear
Effects of oxygen concentration on the metabolism of anisole homologues by rat liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1992, Volume: 22, Issue:11

    Topics: Animals; Anisoles; Benzoflavones; In Vitro Techniques; Male; Microsomes, Liver; Oxygen; Phenobarbital; Phenyl Ethers; Proadifen; Rats; Rats, Wistar

1992
The role of specific cytochromes P450 in the formation of 7,12-dimethylbenz(a)anthracene-protein adducts in rat liver microsomes in vitro.
    Biochemical pharmacology, 1991, Sep-27, Volume: 42, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azo Compounds; Benzoflavones; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Isoenzymes; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazoles; Rats; Troleandomycin

1991
Characterization of covalent binding of [14C]-2-chloro-4-acetotoluidide to microsomes of starling liver and kidney.
    Journal of biochemical toxicology, 1991,Summer, Volume: 6, Issue:2

    Topics: Animals; Benzoflavones; Birds; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Glutathione; In Vitro Techniques; Kidney; Kinetics; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Protein Binding; Sulfhydryl Compounds; Toluidines

1991
Unlabeled hemoglobin adducts of 4,4'-methylenebis (2-chloroaniline) in rats and guinea pigs.
    Archives of toxicology, 1991, Volume: 65, Issue:3

    Topics: Animals; Ascorbic Acid; Benzoflavones; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Guinea Pigs; Hemoglobins; Male; Methylenebis(chloroaniline); Phenobarbital; Rats; Rats, Inbred Strains

1991
Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male Syrian golden hamster liver.
    Journal of steroid biochemistry, 1990, Volume: 35, Issue:2

    Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Cytochrome P-450 Enzyme System; Cytochromes b5; Diethylstilbestrol; Drug Interactions; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug

1990
Modification of 7,8-benzoflavone metabolism in hamster liver and kidney microsomes by hepatic tumor inducing treatments.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Diethylstilbestrol; Flavonoids; Kidney; Liver Neoplasms; Male; Mesocricetus; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Reference Values

1990
Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes.
    Carcinogenesis, 1990, Volume: 11, Issue:1

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Furylfuramide; Humans; Inactivation, Metabolic; Kinetics; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Neoplasms; Nitrofurans; Phenobarbital; Rats; Reference Values; Salmonella typhimurium; Spectrophotometry

1990
Influence of chlordecone and mirex exposure on benzo[a]pyrene metabolism of rat-liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Chlordecone; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Insecticides; Liver; Methylcholanthrene; Microsomes, Liver; Mirex; Pesticide Residues; Phenobarbital; Rats; Subcellular Fractions

1987
Activation of 8-methoxypsoralen by cytochrome P-450. Enzyme kinetics of covalent binding and influence of inhibitors and inducers of drug metabolism.
    Biochemical pharmacology, 1989, May-15, Volume: 38, Issue:10

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Kinetics; Methoxsalen; Microsomes, Liver; Phenobarbital; Protein Binding; Pyridines; Rats; Rats, Inbred Strains

1989
Alteration of methylcholanthrene-mediated suppression of cutaneous delayed hypersensitivity by benzoflavone treatment of C57BL/6J mice.
    Toxicology and applied pharmacology, 1988, Volume: 95, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Drug Hypersensitivity; Enzyme Induction; Female; Flavonoids; Hypersensitivity, Delayed; Immunosuppressive Agents; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Phenobarbital; Polycyclic Compounds; Receptors, Aryl Hydrocarbon; Receptors, Drug

1988
Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases.
    The Journal of biological chemistry, 1987, Feb-05, Volume: 262, Issue:4

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Pyrimidines; Rats; Rats, Inbred F344; Temperature

1987
A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:2

    Topics: Adult; Aniline Hydroxylase; Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; DNA; Dose-Response Relationship, Drug; Female; Humans; Liver; Macaca fascicularis; Macaca mulatta; Male; Mesocricetus; Methylation; Methylcholanthrene; Metyrapone; Mice; Mice, Inbred Strains; Mutagens; Nitrosamines; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity

1986
Synthesis of sex-specific forms of cytochrome P-450 in rat liver is transiently suppressed by hepatic monooxygenase inducers.
    Journal of biochemistry, 1988, Volume: 104, Issue:1

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Female; Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Rats, Inbred Strains; Reference Values; Sex Factors

1988
Qualitative and quantitative differences in the induction and inhibition of hepatic benzo[a]pyrene metabolism in the rat and hamster.
    Biochemical pharmacology, 1988, Apr-15, Volume: 37, Issue:8

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole; Species Specificity

1988
Xenobiotic-metabolizing enzyme systems in test fish--II. The ethylmorphine N-demethylase activity of guppy (Poecilia reticulata) liver.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1987, Volume: 88, Issue:2

    Topics: Animals; Benzoflavones; Cyprinodontiformes; Enzyme Induction; Ethylmorphine-N-Demethylase; Female; Kinetics; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Poecilia

1987
Selective induction and inhibition of the components of 7-ethoxycoumarin O-deethylase activity in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1986
Dioxin treatment of rats results in increased in vitro induction of sister chromatid exchanges by alpha-naphthoflavone: an animal model for human exposure to halogenated aromatics.
    Toxicology and applied pharmacology, 1986, Sep-15, Volume: 85, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 Enzyme System; Dioxins; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Humans; Lymphocytes; Models, Biological; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Sister Chromatid Exchange; Smoking

1986
Chemical modulation of 3-methylindole toxicosis in mice: effect on bronchiolar and olfactory mucosal injury.
    Veterinary pathology, 1986, Volume: 23, Issue:5

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchi; Epithelium; Female; Flavonoids; Glutathione; Indoles; Male; Maleates; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nasal Mucosa; Phenobarbital; Piperonyl Butoxide; Proadifen; Sex Factors; Skatole

1986
Estrogen effects on sister chromatid exchanges in mouse uterine cervical and kidney cells.
    Journal of the National Cancer Institute, 1985, Volume: 75, Issue:3

    Topics: Animals; Benzoflavones; Cells, Cultured; Cervix Uteri; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Female; Indomethacin; Kidney; Mice; Mice, Inbred Strains; Phenobarbital; Pregnancy; Sister Chromatid Exchange

1985
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
    Biochemical pharmacology, 1985, Dec-15, Volume: 34, Issue:24

    Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats

1985
In vitro metabolism of diethylstilbestrol by hepatic, renal and uterine microsomes of rats and hamsters. Effects of different inducers.
    Biochemical pharmacology, 1985, Sep-01, Volume: 34, Issue:17

    Topics: Animals; Benzoflavones; Biotransformation; Chromatography, High Pressure Liquid; Cricetinae; Diethylstilbestrol; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Kidney; Male; Mass Spectrometry; Mesocricetus; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Uterus

1985
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1984, Volume: 79, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout

1984
Nature of N-nitrosodimethylamine demethylase in hepatic microsomes of rats.
    Archives of toxicology, 1984, Volume: 56, Issue:1

    Topics: Aminoacetonitrile; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imidazoles; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Monoamine Oxidase; Niacinamide; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Tranylcypromine

1984
Structure-activity relationships of chlorinated benzenes as inducers of different forms of cytochrome P-450 in rat liver.
    Chemico-biological interactions, 1982, Volume: 41, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Female; Hexachlorobenzene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1982
Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.
    Journal of pharmacobio-dynamics, 1983, Volume: 6, Issue:12

    Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Rats, Inbred Strains

1983
Competition between benzo[a]pyrene and various steroids for cytochrome P-450-dependent rat liver monooxygenases.
    Chemico-biological interactions, 1981, Mar-15, Volume: 34, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; Binding, Competitive; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pregnanolone; Progesterone; Rats; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Substrate Specificity; Testosterone

1981
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
    Biochemical and biophysical research communications, 1980, Apr-14, Volume: 93, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship

1980
Effect of some enzyme inducers, fluids, and methionine-thiosulfate on induced acute aflatoxicosis in goats.
    American journal of veterinary research, 1982, Volume: 43, Issue:2

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Goats; Kidney; Liver; Male; Mortality; Phenobarbital; Phenylbutazone; Water

1982
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:4

    Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone

1983
Reanalysis and clarification of the structures of alpha-naphthoflavone dihydrodiols formed by uninduced and induced rat liver microsomes from Charles River CD and Sprague-Dawley rats.
    Carcinogenesis, 1983, Volume: 4, Issue:4

    Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity

1983
Metabolism of alpha-naphthoflavone and beta-naphthoflavone by rat liver microsomes and highly purified reconstituted cytochrome P-450 systems.
    The Journal of biological chemistry, 1983, May-10, Volume: 258, Issue:9

    Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Flavonoids; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry, Ultraviolet

1983
Multiple effects and metabolism of alpha-naphthoflavone in induced and uninduced hepatic microsomes.
    Basic life sciences, 1983, Volume: 24

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Flavonoids; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Species Specificity

1983
Mutagenic activation of 2,4-diaminoanisole and 2-amino-fluorene by isolated rat liver nuclei and microsomes.
    Chemico-biological interactions, 1980, Volume: 31, Issue:1

    Topics: Animals; Anisoles; Benzoflavones; beta-Naphthoflavone; Cell Nucleus; Cobalt; Flavonoids; Fluorenes; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mutagens; NADP; Phenobarbital; Phenylenediamines; Rats; Salmonella typhimurium

1980
The influence of various enzyme inducers on the microsomal metabolism of 7,8-benzoflavone.
    Carcinogenesis, 1982, Volume: 3, Issue:2

    Topics: Animals; Aroclors; Benzoflavones; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Male; Mass Spectrometry; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1982
The suppressive effect of hepatic 9,000 x G supernatant fraction from 3-methylcholanthrene-treated rats on the mutagenic activity of 2-acetylaminofluorene.
    Japanese journal of pharmacology, 1980, Volume: 30, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; Drug Synergism; Flavonoids; Liver; Male; Methylcholanthrene; Mutagens; Phenobarbital; Rats; Subcellular Fractions

1980
Metabolism of alpha-naphthoflavone by rat liver microsomes.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Flavonoids; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Spectrum Analysis; Time Factors

1981
Toxic chemical depression of the bone marrow and possible aplastic anemia explainable on a genetic basis.
    Clinical toxicology, 1980, Volume: 16, Issue:1

    Topics: Anemia, Aplastic; Animals; Benzoflavones; Benzopyrenes; Bone Marrow Diseases; Flavonoids; Kinetics; Mice; Mice, Inbred Strains; Phenobarbital

1980
The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.
    Chemico-biological interactions, 1995, Jul-14, Volume: 97, Issue:2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Doxorubicin; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; L-Lactate Dehydrogenase; Liver; Male; Maleates; Metyrapone; Mitomycin; Phenobarbital; Rats; Rats, Wistar; Transfection

1995
Induction of tamoxifen-4-hydroxylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), beta-naphthoflavone (beta NF), and phenobarbital (PB) in avian liver: identification of P450 TCDDAA as catalyst of 4-hydroxylation induced by TCDD and beta NF.
    Cancer research, 1994, Jun-15, Volume: 54, Issue:12

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Chick Embryo; Chickens; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Estrogen Antagonists; Female; Humans; Hydroxylation; Immunoglobulin G; Liver; Mesocricetus; Mice; Microsomes, Liver; Models, Biological; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen

1994
Inhibition of PhIP mutagenicity by catechins, and by theaflavins and gallate esters.
    Mutation research, 1997, Mar-17, Volume: 389, Issue:2-3

    Topics: Animals; Antimutagenic Agents; Antioxidants; Benzoflavones; Biflavonoids; Biotransformation; Catechin; Gallic Acid; Hydrolyzable Tannins; Imidazoles; Male; Microsomes, Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Plant Extracts; Rats; Rats, Inbred F344; Salmonella typhimurium

1997
Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain.
    Molecular and cellular biochemistry, 1998, Volume: 189, Issue:1-2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dealkylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Metyrapone; Oxazines; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases

1998
Identification of in vitro cytochrome P450 modulators to detect induction by prototype inducers in the mallard duckling (Anas platyrhynchos).
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1999, Volume: 122, Issue:2

    Topics: Animals; Benzimidazoles; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Ducks; Enzyme Induction; Microsomes, Liver; Oxazines; Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Proadifen

1999
Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.
    Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:6

    Topics: Benzoflavones; beta-Naphthoflavone; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Inactivation, Metabolic; Keratinocytes; Methylcholanthrene; Metyrapone; Oxidoreductases; Phenobarbital; Xenobiotics

2001
The spectrum of enzymes involved in activation of 2-aminoanthracene varies with the metabolic system applied.
    Mutation research, 2005, Sep-05, Volume: 586, Issue:1

    Topics: Animals; Anthracenes; Benzoflavones; beta-Naphthoflavone; Clotrimazole; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hepatocytes; Liver; Male; Mutagenesis; Mutagenicity Tests; Mutagens; Phenobarbital; Rats; Rats, Wistar; Salmonella typhimurium

2005