Page last updated: 2024-08-21

alpha-naphthoflavone and phenacetin

alpha-naphthoflavone has been researched along with phenacetin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's4 (36.36)18.2507
2000's2 (18.18)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Dai, R; Liu, Y; She, M; Wu, Z1
Guo, HF; Jin, J; Li, ZR; Liu, ZY; Xie, ZS; Xue, ST; Yi, H; Zhang, L1
Beaune, PH; Bercovici, JP; Berthou, F; Dreano, Y; Floch, HH; Kerlan, V1
Lennard, MS; Loft, S; Otton, SV; Poulsen, HE; Tucker, GT1
Borm, PJ; Frankhuijzen-Sierevogel, A; Noordhoek, J1
Chiba, K; Echizen, H; Ishizaki, T; Tani, M; Yoshimoto, K1
Greenblatt, DJ; Venkatakrishnan, K; von Moltke, LL1
Hu, YZ; Yao, TW1
Kamimura, H; Noguchi, K; Tenmizu, D1
Boobis, AR; Brodie, MJ; Davies, DS; Kahn, GC; Whyte, C1
Adcock, JM; Daniels, JS; Locuson, CW; Williams, P1

Other Studies

11 other study(ies) available for alpha-naphthoflavone and phenacetin

ArticleYear
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3

    Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2011
Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties.
    European journal of medicinal chemistry, 2020, Aug-15, Volume: 200

    Topics: Animals; Benzofurans; Bone Morphogenetic Protein 2; Caco-2 Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Mice, Inbred BALB C; Molecular Structure; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiophenes; Zebrafish

2020
Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes.
    Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9

    Topics: Adolescent; Adult; Benzoflavones; Caffeine; Child, Preschool; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Estradiol; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Isoenzymes; Kinetics; Male; Microsomes, Liver; Middle Aged; Norpregnenes; Oxidoreductases; Phenacetin; Progesterone Congeners; Tamoxifen; Testosterone

1992
Characterization of metronidazole metabolism by human liver microsomes.
    Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8

    Topics: Acetone; Adult; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mephenytoin; Metronidazole; Microsomes, Liver; Middle Aged; Nifedipine; Phenacetin; Quinidine; Theophylline; Tolbutamide

1991
Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes. The effect of induction with 3-methylcholanthrene and inhibition with alpha-naphthoflavone.
    Biochemical pharmacology, 1983, May-15, Volume: 32, Issue:10

    Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Flavonoids; Humans; Intestinal Mucosa; Kinetics; Male; Methylcholanthrene; Mice; Microsomes; Phenacetin; Rats; Rats, Inbred Strains

1983
Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2.
    British journal of clinical pharmacology, 1995, Volume: 39, Issue:4

    Topics: Aged; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Ditiocarb; Female; Humans; Hydroxylation; In Vitro Techniques; Isoenzymes; Male; Mephenytoin; Microsomes, Liver; Middle Aged; Oxazines; Phenacetin; Propranolol; Quinidine; Recombinant Proteins; Stereoisomerism; Substrate Specificity; Sulfaphenazole; Tolbutamide; Troleandomycin

1995
Human cytochromes P450 mediating phenacetin O-deethylation in vitro: validation of the high affinity component as an index of CYP1A2 activity.
    Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:12

    Topics: Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Omeprazole; Phenacetin; Protein Isoforms; Reproducibility of Results; Sulfaphenazole

1998
Induction of diphenytriazol on cytochrome CYP1A.
    Acta pharmacologica Sinica, 2004, Volume: 25, Issue:4

    Topics: Abortifacient Agents, Nonsteroidal; Aminopyrine; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Female; Fluvoxamine; Microsomes, Liver; Phenacetin; Rats; Rats, Sprague-Dawley; Triazoles

2004
Elucidation of the effects of the CYP1A2 deficiency polymorphism in the metabolism of 4-cyclohexyl-1-ethyl-7-methylpyrido[2,3-d]pyrimidine-2-(1h)-one (YM-64227), a phosphodiesterase type 4 inhibitor, and its metabolites in dogs.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:11

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antibodies, Monoclonal; Area Under Curve; Benzoflavones; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclohexanes; Cytochrome P-450 CYP1A2; Dogs; Genotype; In Vitro Techniques; Microsomes, Liver; Molecular Structure; Phenacetin; Polymorphism, Single Nucleotide; Pyrimidines

2006
Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions.
    Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Coumarins; Cytochrome P-450 Enzyme System; Humans; Kinetics; Male; Metyrapone; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Subcellular Fractions; Substrate Specificity

1981
Evaluation of tizanidine as a marker of canine CYP1A2 activity.
    Journal of veterinary pharmacology and therapeutics, 2016, Volume: 39, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Benzoflavones; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dogs; Enrofloxacin; Female; Fluoroquinolones; Microsomes, Liver; Molecular Probes; Phenacetin; Substrate Specificity; Theophylline

2016