alpha-naphthoflavone has been researched along with omeprazole in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Dai, R; Liu, Y; She, M; Wu, Z | 1 |
| Kheylik, Y; Kondratov, I; Krasavin, M; Naumchyk, V; Platonov, M; Zahanich, I; Zozulya, S | 1 |
| Kovalenko, A; Krasavin, M; Lukin, A; Moore, D; Tikhonova, IG; Zahanich, I; Zhurilo, N; Zozulya, S | 1 |
| Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J | 1 |
| Ding, Q; Fan, G; Gao, D; Jiang, Y; Li, Q; Li, W; Ma, C; Mao, L; Xu, G; Yang, S; Zhang, D; Zhang, S; Zhao, J; Zhao, M; Zhu, L | 1 |
| Hossain, A; Kikuchi, H; Kobayashi, S; Yoshida, H | 1 |
| Greenblatt, DJ; Venkatakrishnan, K; von Moltke, LL | 1 |
| Hossain, A; Kikuchi, H | 1 |
| Kitamura, S; Konishi, T; Nishikawa, H; Taguchi, K | 1 |
| Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL | 1 |
| Ando, M; Ishida, S; Jinno, H; Ohno, Y; Ozawa, S; Sawada, Ji; Tanaka-Kagawa, T | 1 |
| Fukushige, S; Kikuchi, H; Shibazaki, M; Shiratori, Y | 1 |
| Dostalek, M; Jurica, J; Pistovcakova, J; Sulcova, A; Tomandl, J | 1 |
| Kawanishi, M; Shiizaki, K; Yagi, T | 1 |
14 other study(ies) available for alpha-naphthoflavone and omeprazole
| Article | Year |
|---|---|
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity | 2011 |
Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40).
Topics: Animals; Binding Sites; Caco-2 Cells; Cytochrome P-450 Enzyme System; Half-Life; Humans; Methylamines; Mice; Molecular Docking Simulation; Oxadiazoles; Oxazoles; Propionates; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2015 |
Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold.
Topics: Amides; Animals; Drug Delivery Systems; Humans; Hypoglycemic Agents; Mice; Microsomes, Liver; Molecular Docking Simulation; Protein Binding; Receptors, G-Protein-Coupled; Thiadiazoles | 2016 |
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water | 2018 |
Discovery of 1-Amino-1
Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytochrome P-450 Enzyme Inhibitors; Drug Discovery; Humans; Imidazoles; Molecular Docking Simulation; Protein Kinase Inhibitors; Signal Transduction; Structure-Activity Relationship | 2021 |
Induction of cytochrome P-450 1A1 by omeprazole in human HepG2 cells is protein tyrosine kinase-dependent and is not inhibited by alpha-naphthoflavone.
Topics: Benzoflavones; Benzoquinones; Carcinoma, Hepatocellular; Cytochrome P-450 CYP1A1; DNA Topoisomerases, Type I; Enzyme Induction; Enzyme Inhibitors; Humans; Lactams, Macrocyclic; Lung Neoplasms; Omeprazole; Polychlorinated Dibenzodioxins; Protein Binding; Protein-Tyrosine Kinases; Quinones; Receptors, Aryl Hydrocarbon; Regulatory Sequences, Nucleic Acid; Rifabutin; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Human cytochromes P450 mediating phenacetin O-deethylation in vitro: validation of the high affinity component as an index of CYP1A2 activity.
Topics: Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Microsomes, Liver; Omeprazole; Phenacetin; Protein Isoforms; Reproducibility of Results; Sulfaphenazole | 1998 |
Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells.
Topics: Benzoflavones; Benzoquinones; Cytochrome P-450 CYP1A1; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Genistein; Humans; Lactams, Macrocyclic; Liver Neoplasms; Omeprazole; Polychlorinated Dibenzodioxins; Protein-Tyrosine Kinases; Quinones; Receptors, Aryl Hydrocarbon; Rifabutin; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured | 1999 |
Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Combinations; Drugs, Chinese Herbal; Enzyme Inhibitors; Glycyrrhiza; Humans; Isoenzymes; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Paeonia; Phenylpropionates; Quinidine; Recombinant Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Troleandomycin | 1999 |
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection | 2001 |
Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.
Topics: Antigens, Differentiation; Base Sequence; Benzoflavones; Cell Line; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; DNA Primers; Galectin 3; Gene Expression Regulation, Enzymologic; Humans; Oligonucleotide Array Sequence Analysis; Omeprazole; Plasminogen Activator Inhibitor 1; Protein-Tyrosine Kinases; Transcriptional Activation | 2002 |
Presence on human chromosome 10 of omeprazole-sensitivity gene whose product mediates CYP1A1 induction.
Topics: Animals; Benzoflavones; Cell Line; Chromosomes, Human, Pair 10; Cytochrome P-450 CYP1A1; Cytogenetics; Drug Resistance; Enzyme Induction; Gene Expression; Humans; Hybrid Cells; In Situ Hybridization, Fluorescence; Mice; Models, Biological; Omeprazole | 2002 |
The effect of St John's wort (hypericum perforatum) on cytochrome p450 1a2 activity in perfused rat liver.
Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Hypericum; In Vitro Techniques; Liver; Male; Omeprazole; Plant Extracts; Rats; Rats, Wistar | 2011 |
Microbial metabolites of omeprazole activate murine aryl hydrocarbon receptor in vitro and in vivo.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Benzoflavones; Biotransformation; Cecum; Cells, Cultured; Culture Media; Cytochrome P-450 CYP1A1; Humans; Mice; Omeprazole; Receptors, Aryl Hydrocarbon; Saccharomyces cerevisiae | 2014 |