alpha-naphthoflavone has been researched along with metyrapone in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (66.67) | 18.7374 |
| 1990's | 13 (24.07) | 18.2507 |
| 2000's | 4 (7.41) | 29.6817 |
| 2010's | 1 (1.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, Z; Hong, JY; Ning, SM; Smith, TJ; Thomas, PE; Yang, CS | 1 |
| Castranova, V; Goddard, M; Judy, DJ; Pailes, WH; Rabovsky, J | 1 |
| Fantel, AG; Juchau, MR; Lee, QH | 1 |
| Burnett, AK; Craft, JA; Lambard, SE; Wolf, CR | 1 |
| Degawa, M; Funae, Y; Guengerich, FP; Imaoka, S; Inui, Y; Shimada, T; Yamazaki, H | 1 |
| Plewa, MJ; Verdier, MM; Wagner, ED | 1 |
| Gentile, JM; Plewa, MJ; Wagner, ED | 1 |
| Gohda, H; Narimatsu, S; Yamamoto, I; Yoshimura, H | 1 |
| Juchau, MR; Namkung, MJ; Yang, HY | 1 |
| Brunström, B; Lund, J | 1 |
| Hertting, G; Okajima, T | 1 |
| Bender, PE; Eckardt, RD; Leonard, TB; Newton, JF; Romano, MC; Straub, KM | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Koda, A; Konishi, Y; Mori, Y; Nagai, H; Toyoshi, K; Yamazaki, H | 1 |
| Beyerinck, RA; Brass, EP; Garrity, MJ | 1 |
| Dodd, GH; Jenner, J | 1 |
| Burgess, W; Fenech, M; McManus, ME; Morley, AA; Robson, RA; Snyderwine, EG; Stupans, I; Trainor, KJ | 1 |
| Numazawa, M; Satoh, S | 1 |
| Gessner, T; Olson, JR; Wroblewski, VJ | 1 |
| Kairaluoma, M; Pasanen, M; Pelkonen, O; Sotaniemi, EA; Taskinen, T | 1 |
| De Angelis, G; Funari, E; Testai, E; Verdina, A; Vittozzi, L | 1 |
| Boobis, AR; Davies, DS; Whyte, C | 1 |
| Bassi, AM; Ferro, M; Marinari, UM; Nanni, G | 1 |
| Diehl, H; Schröder, U | 1 |
| Judy, DJ; Rabovsky, J | 1 |
| Russell, VA; Taljaard, JJ; Theron, CN | 1 |
| Burke, MD; Mayer, RT; Rawlins, MD; Rettie, AE; Williams, FM | 1 |
| Buhler, DR; Carpenter, HM; Williams, DE | 1 |
| James, OF; Lambert, D; Mutch, E; Rawlins, MD; Williams, FM; Woodhouse, KW | 1 |
| Miyauchi, M | 1 |
| Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
| Bolsen, K; Czarnetzki, BM; Goerz, G; Merk, H | 1 |
| Gielen, JE; Kremers, P; Pasleau, F | 1 |
| Hall, ST; Houston, JB; Rhodes, JC | 1 |
| Cummings, AJ; Kaelin, AC | 1 |
| Gielen, JE; Kremers, P | 1 |
| Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT | 1 |
| DePierre, JW; Meijer, J | 1 |
| Fry, JR | 1 |
| Grafstöm, R; Stohs, SJ | 1 |
| Benford, DJ; Bridges, JW | 1 |
| Dushkin, MI; Menshikova, EB; Pivovarova, EN; Volsky, NN; Zenkov, NK | 1 |
| Barrenscheen, M; Doehmer, J; Glatt, HR; Goeptar, AR; Groot, EJ; Seidel, A; te Koppele, JM; Vermeulen, NP; Wölfel, C | 1 |
| Plewa, MJ | 1 |
| Huang, H; Jurima-Romet, M; Paul, CJ; Solomonraj, G; Thomas, BH | 1 |
| Graham, MA; Hemingway, SA; Riley, RJ; Workman, P | 1 |
| Black, KA; Novicki, DL; Smith, GJ; Vincent, JL | 1 |
| Dhawan, A; Parmar, D; Seth, PK | 1 |
| Alvinerie, M; Dupuy, J; Eeckhoutte, C; Escudero, E; Galtier, P; Sutra, JF | 1 |
| Dusatti, F; Ferro, M; Gelardi, A; Morini, F; Penco, S | 1 |
| Daniel, WA; Haduch, A; Syrek, M | 1 |
| Lin, CH; Lin, PH | 1 |
| Boobis, AR; Brodie, MJ; Davies, DS; Kahn, GC; Whyte, C | 1 |
| Kubickova, B; Martinkova, M; Stiborova, M | 1 |
54 other study(ies) available for alpha-naphthoflavone and metyrapone
| Article | Year |
|---|---|
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
Topics: Animals; Aspirin; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hydroxylation; In Vitro Techniques; Isoenzymes; Lung; Male; Metyrapone; Microsomes; Nasal Mucosa; Nitrosamines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1992 |
Lung cytochrome P450-dependent benzyloxyphenoxazone debenzylase and ethoxyphenoxazone deethylase activities in total microsomal and isolated alveolar type II cells: responses to changes in assay conditions with special reference to non-linear dependence a
Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dicumarol; Enzyme Stability; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Male; Metyrapone; Microsomes; Oxidoreductases; Pulmonary Alveoli; Rats; Rats, Inbred Strains; Sodium Chloride; Sonication; Sucrose | 1990 |
Human embryonic cytochrome P450S: phenoxazone ethers as probes for expression of functional isoforms during organogenesis.
Topics: Antibodies, Monoclonal; Benzoflavones; Biotransformation; Carbon Monoxide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Ethers; Humans; Isoenzymes; Metyrapone; Morphogenesis; Orphenadrine; Oxazines; Oxidoreductases; Xenobiotics | 1991 |
The role of specific cytochromes P450 in the formation of 7,12-dimethylbenz(a)anthracene-protein adducts in rat liver microsomes in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azo Compounds; Benzoflavones; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Isoenzymes; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazoles; Rats; Troleandomycin | 1991 |
Roles of different cytochrome P450 enzymes in bioactivation of the potent hepatocarcinogen 3-methoxy-4-aminoazobenzene by rat and human liver microsomes.
Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Lipids; Male; Metyrapone; Microsomes, Liver; p-Aminoazobenzene; Pyridines; Rats | 1991 |
The biochemical mechanisms of the plant activation of promutagenic aromatic amines.
Topics: Acetaminophen; Benzoflavones; Biotransformation; Catechin; Cell Line; Ditiocarb; Fluorenes; Methimazole; Metyrapone; Mutagens; Mutation; Nicotiana; Oxidoreductases; Oxygenases; Phenylenediamines; Plants, Toxic; Potassium Cyanide | 1990 |
Effects of specific monooxygenase and oxidase inhibitors on the activation of 2-aminofluorene by plant cells.
Topics: Benzoflavones; Biotransformation; Catechin; Ditiocarb; Fluorenes; Methimazole; Metyrapone; Mixed Function Oxygenases; Mutagenicity Tests; Plants; Potassium Cyanide; Salmonella typhimurium | 1989 |
Mechanism of biological formation of cannabielsoin from cannabidiol in the guinea-pig, mouse, rat and rabbit.
Topics: Animals; Benzoflavones; Cannabidiol; Cannabinoids; Chromatography, Gas; Cobalt; Epoxy Compounds; Gas Chromatography-Mass Spectrometry; Guinea Pigs; In Vitro Techniques; Male; Metyrapone; Mice; Mice, Inbred Strains; Microsomes, Liver; Pyridines; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1989 |
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis.
Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac | 1989 |
Differences between chick and turkey embryos in sensitivity to 3,3',4,4'-tetrachloro-biphenyl and in concentration/affinity of the hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Buffers; Centrifugation, Density Gradient; Chick Embryo; Cytosol; Liver; Metyrapone; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug; Species Specificity; Turkeys | 1988 |
The possible involvement of cytochrome P-450 monooxygenase in AVP-induced ACTH secretion.
Topics: Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Benzoflavones; Cytochrome P-450 Enzyme System; Dinoprostone; Indomethacin; Male; Metyrapone; Oxygenases; Piperonyl Butoxide; Pituitary Gland, Anterior; Prostaglandins E; Rats; Rats, Inbred Strains | 1986 |
Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Pyrimidines; Rats; Rats, Inbred F344; Temperature | 1987 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction.
Topics: Adult; Aniline Hydroxylase; Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; DNA; Dose-Response Relationship, Drug; Female; Humans; Liver; Macaca fascicularis; Macaca mulatta; Male; Mesocricetus; Methylation; Methylcholanthrene; Metyrapone; Mice; Mice, Inbred Strains; Mutagens; Nitrosamines; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Inhibition of prostaglandin E2 catabolism and potentiation of hepatic prostaglandin E2 action in rat hepatocytes by inhibitors of oxidative metabolism.
Topics: Aminopyrine; Animals; Benzoflavones; Dinoprostone; Glucagon; Glycogen; Liver; Male; Metyrapone; Oxidation-Reduction; Proadifen; Prostaglandins E; Rats; Rats, Inbred Strains | 1988 |
The interaction of metyrapone and alpha-naphthoflavone with rat olfactory cytochrome P-450.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Flavonoids; Male; Metyrapone; Microsomes; Microsomes, Liver; Nose; Organ Specificity; Oxidoreductases; Oxidoreductases, O-Demethylating; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
Activation of the food-derived mutagen 2-amino-3-methylimidazo[4, 5-f]quinoline by human-liver microsomes.
Topics: Benzoflavones; Biotransformation; Cell Nucleus; Cytochrome P-450 Enzyme System; Fluorenes; Humans; Lymphocytes; Metyrapone; Microsomes, Liver; Quinolines; Salmonella typhimurium | 1988 |
Kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes with various cytochrome P-450 inhibitors.
Topics: Aminoglutethimide; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P450 Family 2; Hydroxylation; Kinetics; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats; Rats, Inbred Strains; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1988 |
Qualitative and quantitative differences in the induction and inhibition of hepatic benzo[a]pyrene metabolism in the rat and hamster.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole; Species Specificity | 1988 |
Inhibitor panel studies of human hepatic and placental cytochrome P-450-associated monooxygenase activities.
Topics: Aminoglutethimide; Animals; Benzoflavones; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Debrisoquin; Enzyme Inhibitors; Female; Furans; Humans; Isoenzymes; Liver; Male; Metyrapone; Oxidoreductases; Placenta; Pregnancy; Rats; Rats, Inbred Strains | 1988 |
Xenobiotic-metabolizing enzyme systems in test fish--II. The ethylmorphine N-demethylase activity of guppy (Poecilia reticulata) liver.
Topics: Animals; Benzoflavones; Cyprinodontiformes; Enzyme Induction; Ethylmorphine-N-Demethylase; Female; Kinetics; Metyrapone; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Poecilia | 1987 |
Selective induction and inhibition of the components of 7-ethoxycoumarin O-deethylase activity in the rat.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Biochemical properties of carcinogen-metabolizing enzymes in cultured hepatoma cells.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cell Line; Cycloheximide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Liver Neoplasms, Experimental; Metyrapone; Protein Biosynthesis; Rats | 1987 |
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine | 1987 |
Cytochrome P450-dependent alkoxyphenoxazone dealkylase activities in lung microsomes from untreated and beta-naphthoflavone-treated rats: effect of in vitro inhibitors.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dealkylation; Flavonoids; In Vitro Techniques; Lung; Male; Metyrapone; Microsomes; Oxidoreductases; Rats; Rats, Inbred Strains | 1987 |
Estrogen-2/4-hydroxylase activities in rat brain and liver microsomes exhibit different substrate preferences and sensitivities to inhibition.
Topics: Animals; Benzoflavones; Brain; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diethylstilbestrol; Female; Kinetics; Male; Metyrapone; Microsomes; Microsomes, Liver; Rats; Rats, Inbred Strains; Steroid Hydroxylases; Substrate Specificity | 1987 |
Major differences between lung, skin and liver in the microsomal metabolism of homologous series of resorufin and coumarin ethers.
Topics: Animals; Benzoflavones; Coumarins; Female; Lung; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes; Microsomes, Liver; Oxazines; Skin; Structure-Activity Relationship | 1986 |
Hexachlorobenzene-induced porphyria in Japanese quail: an in vitro study of changes in cytochrome P-450 and monooxygenases.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Chlorobenzenes; Coturnix; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Female; Hexachlorobenzene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxygenases; Porphyrias; Proadifen | 1985 |
2,5-Diphenyloxazole as a probe for microsomal mono-oxygenation in human and rat liver.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; Oxazoles; Oxygenases; Rats | 1985 |
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout | 1984 |
Nature of N-nitrosodimethylamine demethylase in hepatic microsomes of rats.
Topics: Aminoacetonitrile; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imidazoles; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Monoamine Oxidase; Niacinamide; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Tranylcypromine | 1984 |
Cytochrome P-450-dependent production of chemotactic arachidonate metabolites from human neutrophils.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Arachidonic Acid; Arachidonic Acids; Benzoflavones; Chemotactic Factors; Chemotactic Factors, Eosinophil; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Lipoxygenase; Metyrapone; Microsomes, Liver; Neutrophils; Oxygenases; Pyrazoles; Rats; Rats, Inbred Strains | 1984 |
Competition between benzo[a]pyrene and various steroids for cytochrome P-450-dependent rat liver monooxygenases.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; Binding, Competitive; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pregnanolone; Progesterone; Rats; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Substrate Specificity; Testosterone | 1981 |
Inhibition of antipyrine metabolite formation in rats in vivo.
Topics: Animals; Antipyrine; Benzoflavones; Cimetidine; Cytochrome P-450 Enzyme System; Male; Metyrapone; Proadifen; Rats; Rats, Inbred Strains | 1984 |
Differential inhibition of human placental monooxygenase activity: evidence for multiple forms of 7-ethoxycoumarin O-deethylase.
Topics: 7-Alkoxycoumarin O-Dealkylase; Benzoflavones; Dimethyl Sulfoxide; Epilepsy; Female; Humans; Metyrapone; Oxygenases; Placenta; Pregnancy; Smoking | 1984 |
Mono-oxygenase expression in primary foetal-rat hepatocytes in culture.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Dexamethasone; Female; Isoenzymes; Liver; Metyrapone; Oxygenases; Pregnancy; Rats | 1983 |
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1980 |
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone | 1983 |
A comparison of biphenyl 4-hydroxylation and 4-methoxybiphenyl O-demethylation in rat liver microsomes.
Topics: Animals; Benzoflavones; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Dealkylation; Hydroxylation; Male; Metyrapone; Microsomes, Liver; Rats | 1981 |
Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells.
Topics: Animals; Benzoflavones; Benzopyrenes; Coumarins; Cytochrome P-450 CYP1A1; Female; Intestine, Small; Methylcholanthrene; Metyrapone; Microsomes; Oxidoreductases; Proadifen; Rats; Rats, Inbred Strains; Rotenone | 1981 |
Characterization of the activation of hepatic microsomal hydroxylation by betamethasone and alpha naphthoflavone.
Topics: Animals; Benzoflavones; Betamethasone; Enzyme Activation; Flavonoids; Hydroxylation; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Proadifen; Rats | 1980 |
Ketoconazole inhibits oxidative modification of low density lipoprotein.
Topics: Animals; Benzoflavones; Benzopyrene Hydroxylase; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Humans; Ketoconazole; Lipoproteins, LDL; Luminescent Measurements; Macrophages, Peritoneal; Methoxsalen; Metyrapone; Mice; Mice, Inbred Strains; Oxidation-Reduction | 1995 |
The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Doxorubicin; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; L-Lactate Dehydrogenase; Liver; Male; Maleates; Metyrapone; Mitomycin; Phenobarbital; Rats; Rats, Wistar; Transfection | 1995 |
Blocking the plant activation of promutagenic aromatic amines by peroxidase inhibitors.
Topics: Acetaminophen; Antimutagenic Agents; Benzoflavones; Catechin; Cells, Cultured; Ditiocarb; Methimazole; Metyrapone; Mutagenicity Tests; Mutagens; Peroxidases; Plants; Potassium Cyanide; Prodrugs; Salmonella typhimurium | 1993 |
Metabolism of phenazopyridine by isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Detergents; Enzyme Induction; In Vitro Techniques; Indomethacin; Liver; Male; Metyrapone; Octoxynol; Phenazopyridine; Polyethylene Glycols; Proadifen; Rats; Rats, Wistar | 1993 |
Initial characterization of the major mouse cytochrome P450 enzymes involved in the reductive metabolism of the hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (tirapazamine, SR 4233, WIN 59075).
Topics: Animals; Antineoplastic Agents; Benzoflavones; Carbon Monoxide; Cell Hypoxia; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oxidation-Reduction; Oxygen; Tirapazamine; Triazines | 1993 |
Flow cytometric analysis of xenobiotic metabolism activity in isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Flow Cytometry; Fluoresceins; Light; Liver; Male; Metyrapone; Mixed Function Oxygenases; Proadifen; Rats; Xenobiotics | 1993 |
Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dealkylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Metyrapone; Oxazines; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases | 1998 |
In vitro metabolism of 14C-moxidectin by hepatic microsomes from various species.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antinematodal Agents; Benzoflavones; Carbon Radioisotopes; Cattle; Clotrimazole; Deer; Enzyme Inhibitors; Female; Macrolides; Male; Metyrapone; Microsomes, Liver; Pesticide Synergists; Piperonyl Butoxide; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Sheep; Swine | 2001 |
Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.
Topics: Benzoflavones; beta-Naphthoflavone; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Inactivation, Metabolic; Keratinocytes; Methylcholanthrene; Metyrapone; Oxidoreductases; Phenobarbital; Xenobiotics | 2001 |
The contribution of cytochrome P-450 isoenzymes to the metabolism of phenothiazine neuroleptics.
Topics: Alcohol Oxidoreductases; Analgesics, Non-Narcotic; Animals; Antipsychotic Agents; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Isoenzymes; Kinetics; Male; Methylation; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Perazine; Promazine; Quinine; Rats; Rats, Wistar; Steroid Hydroxylases; Substrate Specificity | 2002 |
Induction of ROS formation, poly(ADP-ribose) polymerase-1 activation, and cell death by PCB126 and PCB153 in human T47D and MDA-MB-231 breast cancer cells.
Topics: Benzoflavones; Breast Neoplasms; Catalase; Cell Line, Tumor; Cell Survival; Chelating Agents; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Fluoresceins; Humans; Metyrapone; Molecular Structure; NAD; NADP; Oxidation-Reduction; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Polychlorinated Biphenyls; Reactive Oxygen Species; Tamoxifen | 2006 |
Biphasic O-deethylation of phenacetin and 7-ethoxycoumarin by human and rat liver microsomal fractions.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Coumarins; Cytochrome P-450 Enzyme System; Humans; Kinetics; Male; Metyrapone; Microsomes, Liver; Phenacetin; Rats; Rats, Wistar; Subcellular Fractions; Substrate Specificity | 1981 |
Effects of cytochrome P450 inhibitors on peroxidase activity.
Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin | 2012 |