Page last updated: 2024-08-21

alpha-naphthoflavone and furafylline

alpha-naphthoflavone has been researched along with furafylline in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's6 (60.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Hashizume, H; Kawasaki, M; Komatsu, M; Matsumoto, M; Sasaki, H; Shimokawa, Y; Tomishige, T; Tsubouchi, H1
Dai, R; Liu, Y; She, M; Wu, Z1
Bellow, SM; Bratton, MR; Chatters, AJ; Foroozesh, M; Goyal, N; Liu, J; Lovings, LJ; Mensah, LM; Pham, PT; Skripnikova, EV; Wang, G; Wang, Y; Wiese, TE; Zhao, M; Zheng, S1
Gelboin, HV; Goldfarb, IS; Tsyrlov, IB1
Bu, HZ; Knuth, K; Magis, L; Teitelbaum, P1
Fernandez, M; Hashemi, E; Ioannides, C; Lewis, DF; Papagiannidou, E; Skene, DJ; Snelling, J1
Audus, KL; Avery, ML; Meek, CE1
Abolfathi, Z; Beaune, P; Labbé, L; Lessard, E; Pakdel, H; Turgeon, J1
Adcock, JM; Daniels, JS; Locuson, CW; Williams, P1

Reviews

1 review(s) available for alpha-naphthoflavone and furafylline

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Other Studies

9 other study(ies) available for alpha-naphthoflavone and furafylline

ArticleYear
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
    PLoS medicine, 2006, Volume: 3, Issue:11

    Topics: Animals; Antitubercular Agents; Blood; Cell Line; Humans; In Vitro Techniques; Intracellular Membranes; Macrophages; Mammals; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Mycobacterium; Mycobacterium bovis; Mycolic Acids; Nitroimidazoles; Oxazoles; Treatment Outcome; Tuberculosis

2006
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3

    Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2011
A Ligand-Based Drug Design. Discovery of 4-Trifluoromethyl-7,8-pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2.
    Journal of medicinal chemistry, 2015, Aug-27, Volume: 58, Issue:16

    Topics: Cell Line, Tumor; Coumarins; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Humans; Kinetics; Ligands; Models, Chemical; Receptors, Aryl Hydrocarbon; Structure-Activity Relationship

2015
Enzyme-kinetic and immunochemical characteristics of mouse cDNA-expressed, microsomal, and purified CYP1A1 and CYP1A2.
    Archives of biochemistry and biophysics, 1993, Volume: 307, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Benzoflavones; Cell Line; Cloning, Molecular; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Isoenzymes; Mice; Microsomes, Liver; Multigene Family; Oxidoreductases; Recombinant Proteins; Theophylline; Vaccinia virus

1993
High-throughput cytochrome P450 (CYP) inhibition screening via a cassette probe-dosing strategy. V. Validation of a direct injection/on-line guard cartridge extraction--tandem mass spectrometry method for CYP1A2 inhibition assessment.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2001, Volume: 12, Issue:4

    Topics: Benzoflavones; Biological Assay; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; Humans; Mass Spectrometry; Microsomes, Liver; Oxazines; Theophylline

2001
Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.
    Journal of pineal research, 2001, Volume: 31, Issue:4

    Topics: Animals; Benzoflavones; Chlorzoxazone; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Melatonin; Microsomes, Liver; Models, Molecular; NADP; Oxidation-Reduction; Rats; Rats, Wistar; Theophylline

2001
The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.
    Placenta, 2003, Volume: 24, Issue:1

    Topics: Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Methylcholanthrene; Microsomes, Liver; Smoking; Theophylline; Trophoblasts; Tumor Cells, Cultured

2003
Role of specific cytochrome P450 enzymes in the N-oxidation of the antiarrhythmic agent mexiletine.
    Xenobiotica; the fate of foreign compounds in biological systems, 2003, Volume: 33, Issue:1

    Topics: Anti-Arrhythmia Agents; Benzoflavones; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Humans; Hydroxylation; Kinetics; Mexiletine; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Saccharomyces cerevisiae; Theophylline

2003
Evaluation of tizanidine as a marker of canine CYP1A2 activity.
    Journal of veterinary pharmacology and therapeutics, 2016, Volume: 39, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Benzoflavones; Clonidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dogs; Enrofloxacin; Female; Fluoroquinolones; Microsomes, Liver; Molecular Probes; Phenacetin; Substrate Specificity; Theophylline

2016