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alpha-naphthoflavone and flunitrazepam

alpha-naphthoflavone has been researched along with flunitrazepam in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bochner, F; Coller, JK; Somogyi, AA	1
Greenblatt, DJ; Hesse, LM; Shader, RI; Venkatakrishnan, K; von Moltke, LL	1

Other Studies

2 other study(ies) available for alpha-naphthoflavone and flunitrazepam

Article	Year
Flunitrazepam oxidative metabolism in human liver microsomes: involvement of CYP2C19 and CYP3A4. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:10 Topics: Acetonitriles; Adult; Aged; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dimethylformamide; Enzyme Activation; Female; Flunitrazepam; Genotype; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Solvents	1999
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam. Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2 Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection	2001

Article

Year

Flunitrazepam oxidative metabolism in human liver microsomes: involvement of CYP2C19 and CYP3A4.

Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:10

Topics: Acetonitriles; Adult; Aged; Antibodies, Monoclonal; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dimethylformamide; Enzyme Activation; Female; Flunitrazepam; Genotype; Humans; Kinetics; Male; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Oxidation-Reduction; Solvents

1999

CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2

Topics: Anti-Anxiety Agents; Benzoflavones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flunitrazepam; Humans; Hydroxylation; Isoenzymes; Ketoconazole; Kinetics; Methylation; Microsomes, Liver; Mixed Function Oxygenases; Omeprazole; Quinidine; Ritonavir; Sulfaphenazole; Transfection

2001