Page last updated: 2024-08-21

alpha-naphthoflavone and caffeine

alpha-naphthoflavone has been researched along with caffeine in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (22.22)	18.7374
1990's	4 (44.44)	18.2507
2000's	2 (22.22)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartel, K; Bracher, F; Christianson, DW; Herp, D; Jung, M; Marek, M; Müller, M; Ong, N; Porter, NJ; Robaa, D; Romier, C; Schmidtkunz, K; Senger, J; Shaik, TB; Sippl, W; Vögerl, K	1
Birkett, DJ; Gonzalez, FJ; McManus, ME; Miners, JO; Mohamed, Z; Quattrochi, LC; Tassaneeyakul, W; Tukey, RH; Veronese, ME	1
Beaune, PH; Bercovici, JP; Berthou, F; Dreano, Y; Floch, HH; Kerlan, V	1
Lennard, MS; Loft, S; Otton, SV; Poulsen, HE; Tucker, GT	1
Birkett, DJ; Matthews, AP; McManus, ME; Meller, D; Miners, JO; Robson, RA; Stupans, I	1
Campbell, ME; Grant, DM; Kalow, W; Tang, BK	1
Lee, CA; Manyike, PT; Nelson, SD; Slattery, JT; Thummel, KE	1
Commandeur, JN; Damsten, MC; Maasdijk, DM; van Vugt-Lussenburg, BM; Vermeulen, NP	1
Aarts, JM; Baykus, H; de Kok, TM; de Waard, PW; Hoogenboom, RL; Peijnenburg, AA; van Schooten, FJ	1

Trials

1 trial(s) available for alpha-naphthoflavone and caffeine

Article	Year
A human intervention study with foods containing natural Ah-receptor agonists does not significantly show AhR-mediated effects as measured in blood cells and urine. Chemico-biological interactions, 2008, Oct-22, Volume: 176, Issue:1 Topics: Adult; Benzoflavones; Beverages; Biotransformation; Brassicaceae; Caffeine; Cell Separation; Citrus paradisi; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation; Humans; Lymphocytes; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Plasma; Polychlorinated Dibenzodioxins; Principal Component Analysis; Reagent Kits, Diagnostic; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tissue Extracts; Urine	2008

Article

Year

A human intervention study with foods containing natural Ah-receptor agonists does not significantly show AhR-mediated effects as measured in blood cells and urine.

Chemico-biological interactions, 2008, Oct-22, Volume: 176, Issue:1

Topics: Adult; Benzoflavones; Beverages; Biotransformation; Brassicaceae; Caffeine; Cell Separation; Citrus paradisi; Cytochrome P-450 Enzyme System; Female; Gene Expression Regulation; Humans; Lymphocytes; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Plasma; Polychlorinated Dibenzodioxins; Principal Component Analysis; Reagent Kits, Diagnostic; Receptors, Aryl Hydrocarbon; RNA, Messenger; Tissue Extracts; Urine

2008

Other Studies

8 other study(ies) available for alpha-naphthoflavone and caffeine

Article	Year
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Acetylation; Animals; Catalytic Domain; Cells, Cultured; Crystallography, X-Ray; Histone Deacetylase 6; Histone Deacetylase Inhibitors; HL-60 Cells; Humans; Hydroxamic Acids; In Vitro Techniques; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Phenothiazines; Structure-Activity Relationship; Zebrafish	2019
Caffeine as a probe for human cytochromes P450: validation using cDNA-expression, immunoinhibition and microsomal kinetic and inhibitor techniques. Pharmacogenetics, 1992, Volume: 2, Issue:4 Topics: Benzoflavones; Biomarkers; Caffeine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating	1992
Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes. Biochemical pharmacology, 1992, Nov-03, Volume: 44, Issue:9 Topics: Adolescent; Adult; Benzoflavones; Caffeine; Child, Preschool; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Estradiol; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Isoenzymes; Kinetics; Male; Microsomes, Liver; Middle Aged; Norpregnenes; Oxidoreductases; Phenacetin; Progesterone Congeners; Tamoxifen; Testosterone	1992
Characterization of metronidazole metabolism by human liver microsomes. Biochemical pharmacology, 1991, Apr-15, Volume: 41, Issue:8 Topics: Acetone; Adult; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mephenytoin; Metronidazole; Microsomes, Liver; Middle Aged; Nifedipine; Phenacetin; Quinidine; Theophylline; Tolbutamide	1991
Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies. Biochemical pharmacology, 1988, May-01, Volume: 37, Issue:9 Topics: Adult; Benzoflavones; Caffeine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Humans; Immunologic Techniques; In Vitro Techniques; Isoenzymes; Kinetics; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Verapamil	1988
Biotransformation of caffeine by microsomes from human liver. Kinetics and inhibition studies. Biochemical pharmacology, 1987, Apr-15, Volume: 36, Issue:8 Topics: Adult; Benzoflavones; Biotransformation; Caffeine; Cytochrome P-450 Enzyme Inhibitors; Dealkylation; Female; Humans; Imidazoles; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Oxazines	1987
Mechanism of cytochrome P450 activation by caffeine and 7,8-benzoflavone in rat liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:10 Topics: Animals; Benzoflavones; Benzoquinones; Caffeine; Cytochrome P-450 Enzyme System; Cytochromes b5; Electron Transport; Enzyme Activation; Imines; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Sprague-Dawley	1997
Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3. Biochemical and biophysical research communications, 2006, Aug-04, Volume: 346, Issue:3 Topics: Acetaminophen; Amodiaquine; Arginine; Benzoflavones; Caffeine; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Activation; Humans; Kinetics; Leucine; Molecular Structure; Mutation; N-Methyl-3,4-methylenedioxyamphetamine; Pharmaceutical Preparations; Phenylalanine; Substrate Specificity	2006