alpha-naphthoflavone has been researched along with benzo(a)pyrene in 67 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (40.30) | 18.7374 |
| 1990's | 18 (26.87) | 18.2507 |
| 2000's | 18 (26.87) | 29.6817 |
| 2010's | 3 (4.48) | 24.3611 |
| 2020's | 1 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Hardin, JA; Hinoshita, F; Sherr, DH | 1 |
| Guengerich, FP; Shimada, T; Yun, CH | 1 |
| Hirohata, T; Kiyohara, C; Masuda, Y; Omura, M | 1 |
| Kawabata, TT; Ladics, GS; White, KL | 1 |
| Brauze, D; Kotecki, M; Mikstacka, R | 1 |
| Antignac, E; Cassand, P; Grolier, P; Koch, B; Narbonne, JF | 1 |
| Crouch, LS; Ebel, RE | 1 |
| Juchau, MR; Namkung, MJ; Yang, HY | 1 |
| Babich, H; Borenfreund, E; Sardana, MK | 1 |
| Fukuhara, M; Ohno, Y; Sunouchi, M; Takanaka, A | 1 |
| Gessner, T; Olson, JR; Wroblewski, VJ | 1 |
| Maddock, MB; Milling, DM | 1 |
| Kawabata, TT; White, KL | 1 |
| Bogdanffy, MS; Brown, DR; Roberts, AE; Schatz, RA | 1 |
| Bickers, DR; Das, M; Kaufmann, I; Merk, HF; Mukhtar, H | 1 |
| Reiners, JJ | 1 |
| Domin, BA; Philpot, RM | 1 |
| Johnson, EF; Raucy, JL | 1 |
| Merk, H | 1 |
| Bronkhorst, AM; Hukkelhoven, MW; Vermorken, AJ | 1 |
| Genta, VM; Mass, MJ | 1 |
| Melius, P; Swain, L | 1 |
| Miyauchi, M | 1 |
| Manchester, DK | 1 |
| Mason, ME; Okey, AB | 1 |
| Bloemendal, H; Goos, CM; Henderson, PT; Hukkelhoven, MW; Vermorken, AJ | 1 |
| Conney, AH; Coon, MJ; Huang, MT; Johnson, EF; Koop, DR; Muller-Eberhard, U | 1 |
| MacLeod, MC; Mansfield, BK; Selkirk, JK | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 1 |
| Goldstein, JA; Huckins, JN; Linko, P; Stalling, DL | 1 |
| Jernström, B; Nordenskjöld, M | 1 |
| Katz, M; Raj, AS | 1 |
| Mattison, DR; Shiromizu, K | 1 |
| Cassand, PM; Michel, XR; Narbonne, JF | 1 |
| Busbee, DL; Campbell, BD; Carvan, MJ; Flood, LP | 1 |
| Kupfer, D; Lee, CA; Mani, C; Rifkind, AB | 1 |
| Doehmer, J; Jensen, KG; Loft, S; Onfelt, A; Poulsen, HE | 1 |
| Hines, RN; Novak, RF; Quan, T; Runge-Morris, M; States, JC | 1 |
| Burchiel, SW; Davila, DR; Romero, DL | 1 |
| Faller, DV; Vaziri, C | 1 |
| Buters, JT; Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC | 1 |
| Born, JL; Burchiel, SW; Lauer, FT; Mounho, BJ; Romero, DL | 1 |
| Barton, SL; Burchiel, SW; Ethier, SP; Tannheimer, SL | 1 |
| Burchiel, SW; Mounho, BJ | 1 |
| Gogate, SU; Mann, KK; Matulka, RA; Near, RI; Sherr, DH; Trombino, AF | 1 |
| Broccoli, M; Ferreri, AM; Mazzullo, M; Paolini, M; Perocco, P; Rocchi, P | 1 |
| Brauze, D; Malejka-Giganti, D | 1 |
| Bartels, MJ; Carney, EW; Charles, GD; Freshour, NL; Gollapudi, BB; Zacharewski, TR | 1 |
| Annas, A; Brittebo, E; Hellman, B | 1 |
| Borish, L; Negri, J; Pacheco, KA; Rosenwasser, LJ; Sterritt, C; Tarkowski, M | 1 |
| Chirnomas, RB; Jeffy, BD; Romagnolo, DF | 1 |
| Buesen, R; Jacob, J; Lampen, A; Mock, M; Nau, H; Seidel, A | 1 |
| Erne, P; Niermann, T; Resink, T; Schmutz, S | 1 |
| Amiot, L; Fardel, O; Fauchet, R; Le Ferrec, E; Le Vee, M; Rion, S; van Grevenynghe, J | 1 |
| Liu, SH; Tsai, KS; Yang, RS | 1 |
| Huang, YP; Hung, CC; Ueng, TH; Wang, HW | 1 |
| Cavret, S; Feidt, C | 1 |
| Gupta, YK; Kumar, A; Patel, S; Singh, MP | 1 |
| Brion, F; Cheshenko, K; Eggen, RI; Hinfray, N; Kah, O; Le Page, Y; Pakdel, F; Segner, H | 1 |
| Chun, YJ; Chung, JY; Hong, YP; Kim, JM; Kim, JY; Kim, WR; Kim, YJ; Lee, SG; Oh, S; Park, JE; Park, YC; Yoo, KS; Yoo, YH | 1 |
| Lee, ME; Urso, P | 1 |
| Chen, XM; Liu, AL; Lu, WQ; Wei, W; Xie, SH; Zhang, C | 1 |
| Bugiak, B; Weber, LP | 1 |
| Bartz, H; Braunbeck, T; Erdinger, L; Heeg, K; Mayer, A; Ulrich, K; Wölfle, S | 1 |
| Fardel, O; Lagadic-Gossmann, D; Le Ferrec, E; Mayati, A | 1 |
| Fang, WF; Fu, YX; Gao, SH; Huang, YC; Liang, F; Liu, Z; Qu, LW; Wang, GZ; Yu, H; Zhang, C; Zhang, L; Zhao, XC; Zhou, GB; Zhou, YC | 1 |
| de Oliveira, C; Fanali, LZ; Sturve, J | 1 |
1 review(s) available for alpha-naphthoflavone and benzo(a)pyrene
| Article | Year |
|---|---|
[Benzo(a)pyrene metabolism in human fibroblasts--effect of 7,8-benzoflavone].
Topics: Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Chromatography, High Pressure Liquid; Culture Media; Depression, Chemical; Fibroblasts; Humans; In Vitro Techniques | 1990 |
66 other study(ies) available for alpha-naphthoflavone and benzo(a)pyrene
| Article | Year |
|---|---|
Mechanisms by which benzo[a]pyrene, an environmental carcinogen, suppresses B cell lymphopoiesis.
Topics: Animals; Apoptosis; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Bone Marrow; Cell Division; Cells, Cultured; Down-Regulation; Immune Tolerance; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1992 |
Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
Topics: Antibodies; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 Enzyme System; Gene Expression; Humans; Hydroxylation; Isoenzymes; Kinetics; Liver; Microsomes, Liver; Norpregnenes; Recombinant Proteins; Saccharomyces cerevisiae; Sulfaphenazole | 1992 |
Comparison of suppression of mutagenicity of benzo(a)pyrene among methylsulfonyl polychlorinated biphenyl isomers.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Cells, Cultured; Humans; Mutagenicity Tests; Polychlorinated Biphenyls | 1992 |
Suppression of the in vitro humoral immune response of mouse splenocytes by 7,12-dimethylbenz[a]anthracene metabolites and inhibition of immunosuppression by alpha-naphthoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Benzo(a)pyrene; Benzoflavones; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Erythrocytes; Female; Immunosuppressive Agents; Mice; Spleen | 1991 |
Prochloraz as potent inhibitor of benzo[a]pyrene metabolism and mutagenic activity in rat liver fractions.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Fungicides, Industrial; Imidazoles; Liver; Male; Methylcholanthrene; Miconazole; Mutagenicity Tests; Rats; Rats, Inbred Strains | 1990 |
Influence of chlordecone and mirex exposure on benzo[a]pyrene metabolism of rat-liver microsomes.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Chlordecone; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Insecticides; Liver; Methylcholanthrene; Microsomes, Liver; Mirex; Pesticide Residues; Phenobarbital; Rats; Subcellular Fractions | 1987 |
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis.
Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac | 1989 |
Acute cytotoxicities of polynuclear aromatic hydrocarbons determined in vitro with the human liver tumor cell line, HepG2.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aroclors; Benzo(a)pyrene; Benzoflavones; Carcinoma, Hepatocellular; Cell Line; Cell Survival; Humans; Liver Neoplasms; Neutral Red; Oxygenases; Polycyclic Compounds | 1988 |
Effects of various inducers on the activities of cytochrome P-450-mixed function oxidases and aflatoxin B1 activation in microsomes of hamster livers.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cricetinae; DNA; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases | 1988 |
Qualitative and quantitative differences in the induction and inhibition of hepatic benzo[a]pyrene metabolism in the rat and hamster.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole; Species Specificity | 1988 |
Activation and detoxication of promutagens by toadfish (Opsanus tau) hepatic postmitochondrial fractions in the Salmonella assay.
Topics: Animals; Anthracenes; Aroclors; Benzo(a)pyrene; Benzoflavones; Biotransformation; Dose-Response Relationship, Drug; Fishes; Inactivation, Metabolic; Microsomes, Liver; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium | 1986 |
Suppression of the vitro humoral immune response of mouse splenocytes by benzo(a)pyrene metabolites and inhibition of benzo(a)pyrene-induced immunosuppression by alpha-naphthoflavone.
Topics: Animals; Antibody Formation; Benzo(a)pyrene; Benzoflavones; Dose-Response Relationship, Drug; Flavonoids; Immunosuppression Therapy; Mice; Spleen | 1987 |
Regioselective inhibition of benzo(a)pyrene metabolism by corticosterone in comparison with metyrapone and alpha-naphthoflavone.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Chromatography, High Pressure Liquid; Corticosterone; Cytochrome P-450 Enzyme System; Drug Interactions; Flavonoids; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Pyridines; Rats; Rats, Inbred Strains | 1986 |
Human hair follicle benzo[a]pyrene and benzo[a]pyrene 7,8-diol metabolism: effect of exposure to a coal tar-containing shampoo.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Carbon Monoxide; Clotrimazole; Coal Tar; Dihydroxydihydrobenzopyrenes; DNA; Drug Interactions; Enzyme Induction; Hair; Hair Preparations; Humans; Ketoconazole; NADP | 1987 |
Differential effects of 7,8-benzoflavone on polycyclic aromatic hydrocarbon dependent mutagenesis and cytotoxicity in a keratinocyte cell-mediated mutation assay.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cells, Cultured; Cricetinae; Cricetulus; Epidermis; Flavonoids; Mice; Mutagenicity Tests; Mutagens | 1985 |
The effect of substrate on the expression of activity catalyzed by cytochrome P-450: metabolism mediated by rabbit isozyme 6 in pulmonary microsomal and reconstituted monooxygenase systems.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Catalysis; Chromatography, DEAE-Cellulose; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Isoenzymes; Lung; Male; Microsomes; Microsomes, Liver; Oxazines; Oxygenases; Polychlorinated Dibenzodioxins; Rabbits | 1986 |
Variations among untreated rabbits in benzo(a)pyrene metabolism and its modulation by 7,8-benzoflavone.
Topics: Animals; Antibodies, Monoclonal; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Flavonoids; In Vitro Techniques; Microsomes, Liver; Polychlorinated Dibenzodioxins; Rabbits; Rifampin | 1985 |
[Metabolism of foreign substances in human skin and hair follicles].
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Culture Techniques; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Repression; Furans; Hair; Humans; Microsomes; Pyridines; Skin | 1985 |
Covalent binding of BP-metabolites to DNA of cultured human hair follicle keratinocytes.
Topics: Benzo(a)pyrene; Benzoflavones; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; DNA; Hair; Humans; Trichloroepoxypropane | 1985 |
Inhibition of binding of benzo(a)pyrene to DNA by 7,8-benzoflavone in organ cultures of human bronchus.
Topics: Benzo(a)pyrene; Benzoflavones; Biopsy; Bronchi; DNA; Flavonoids; Humans; Lung Neoplasms; Organ Culture Techniques | 1985 |
Characterization of benzo[a]pyrene metabolites formed by 3-methylcholanthrene-induced goldfish, black bullhead and brown bullhead.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Chromatography, High Pressure Liquid; Fishes; Goldfish; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Polycyclic Compounds; Rats; Rats, Inbred Strains; Trichloroepoxypropane | 1984 |
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout | 1984 |
Range of environmentally responsive monooxygenase activities in human placental microsomes determined by direct fluorescence techniques.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Female; Humans; In Vitro Techniques; Kinetics; Microsomes; Oxazines; Placenta; Pregnancy; Smoking; Spectrometry, Fluorescence | 1981 |
Aryl hydrocarbon hydroxylase activity in mouse, rat, and human mammary tumors.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Breast Neoplasms; Enzyme Induction; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Microsomes; Rats | 1981 |
Metabolism of benzo(a)pyrene in bovine lens epithelium.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Cattle; Cells, Cultured; DNA; Epithelium; Epoxide Hydrolases; Lens, Crystalline; Trichloroepoxypropane | 1981 |
Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; Cytochrome P-450 Enzyme System; Flavonoids; Isoenzymes; Kinetics; Microsomes, Liver; Rabbits | 1981 |
Time course of metabolism of benzo[e]pyrene by hamster embryo cells and the effect of chemical modifiers.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Carcinogens; Cells, Cultured; Cricetinae; Dihydroxydihydrobenzopyrenes; Embryo, Mammalian; Isomerism; Kinetics | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Structure-activity relationships of chlorinated benzenes as inducers of different forms of cytochrome P-450 in rat liver.
Topics: Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Chlorobenzenes; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Female; Hexachlorobenzene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1982 |
Induction and repair of DNA strand breaks in cultured human fibroblasts exposed to various phenols and dihydrodiols of benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Cells, Cultured; DNA; DNA Repair; DNA, Single-Stranded; Fibroblasts; Humans; Male; Microsomes, Liver; Phenols; Rats | 1982 |
Inhibitory effect of 7,8-benzoflavone on DMBA- and BaP-induced bone marrow micronuclei in mouse.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Bone Marrow; Cell Nucleus; Chromosomes; Female; Flavonoids; Mice; Time Factors | 1983 |
The effect of intraovarian injection of benzo(a)pyrene on primordial oocyte number and ovarian aryl hydrocarbon [benzo(a)pyrene] hydroxylase activity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Cell Count; Dose-Response Relationship, Drug; Female; Injections; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oocytes; Ovary | 1984 |
Activation of benzo[a]pyrene and 2-aminoanthracene to bacteria mutagens by mussel digestive gland postmitochondrial fraction.
Topics: Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Bivalvia; Cadmium; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver Extracts; Mixed Function Oxygenases; Mutagenicity Tests; Mutagens; NADPH-Ferrihemoprotein Reductase; Polychlorinated Biphenyls; Salmonella typhimurium | 1993 |
Effects of benzo(a)pyrene and tetrachlorodibenzo(p)dioxin on fetal dolphin kidney cells: inhibition of proliferation and initiation of DNA damage.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cell Division; Cell Line; DNA Adducts; DNA Damage; DNA Repair; Dolphins; Kidney; Polychlorinated Dibenzodioxins | 1995 |
Induction of tamoxifen-4-hydroxylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), beta-naphthoflavone (beta NF), and phenobarbital (PB) in avian liver: identification of P450 TCDDAA as catalyst of 4-hydroxylation induced by TCDD and beta NF.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Chick Embryo; Chickens; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Induction; Estrogen Antagonists; Female; Humans; Hydroxylation; Immunoglobulin G; Liver; Mesocricetus; Mice; Microsomes, Liver; Models, Biological; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Sprague-Dawley; Species Specificity; Tamoxifen | 1994 |
Effects of benzo[a]pyrene and (+-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene on mitosis in Chinese hamster V79 cells with stable expression of rat cytochrome P4501A1 or 1A2.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cell Line; Cell Survival; Cricetinae; Cricetulus; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Mitosis; Oxidoreductases; Rats; Transfection | 1993 |
Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Base Sequence; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cadmium; Cadmium Compounds; Chimera; Cytochrome P-450 Enzyme System; DNA Repair; Enzyme Induction; Fibroblasts; Gene Expression Regulation, Enzymologic; Genetic Vectors; Humans; Isoenzymes; Mice; Molecular Sequence Data; Plasmids; RNA, Messenger; Sulfates; Transfection; Transformation, Genetic; Xeroderma Pigmentosum | 1993 |
Human T cells are highly sensitive to suppression of mitogenesis by polycyclic aromatic hydrocarbons and this effect is differentially reversed by alpha-naphthoflavone.
Topics: Adult; Benzo(a)pyrene; Benzoflavones; Carcinogens; Cells, Cultured; Female; Humans; Immune System; Immunosuppression Therapy; Leukocyte Count; Male; Mitosis; Polycyclic Aromatic Hydrocarbons; Structure-Activity Relationship; T-Lymphocytes | 1996 |
A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Benzoflavones; Cell Cycle; Cell Division; Cell Nucleus; DNA Damage; G1 Phase; Growth Substances; Helix-Loop-Helix Motifs; Kinetics; Mice; Mutagenesis; Neoplasm Proteins; Nuclear Proteins; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Proto-Oncogenes; Receptors, Aryl Hydrocarbon; Recombinant Proteins; Transfection; Tumor Suppressor Protein p53 | 1997 |
Differential mechanisms of cytochrome P450 inhibition and activation by alpha-naphthoflavone.
Topics: Benzo(a)pyrene; Benzoflavones; Carbon Monoxide; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Humans; Kinetics; Mixed Function Oxygenases; Models, Chemical; Photolysis | 1997 |
Depletion of glutathione by benzo(a)pyrene metabolites, ionomycin, thapsigargin, and phorbol myristate in human peripheral blood mononuclear cells.
Topics: Benzo(a)pyrene; Benzoflavones; Calcium; Enzyme Activation; Glutathione; Humans; Ionomycin; Lymphocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 1997 |
Carcinogenic polycyclic aromatic hydrocarbons increase intracellular Ca2+ and cell proliferation in primary human mammary epithelial cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benzo(a)pyrene; Benzoflavones; Breast; Breast Neoplasms; Calcium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Homeostasis; Humans; Intracellular Fluid; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons | 1997 |
Alterations in human B cell calcium homeostasis by polycyclic aromatic hydrocarbons: possible associations with cytochrome P450 metabolism and increased protein tyrosine phosphorylation.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Benzoquinones; Calcium; Cell Line; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Humans; Lactams, Macrocyclic; Protein-Tyrosine Kinases; Quinones; Rifabutin | 1998 |
Regulation of preB cell apoptosis by aryl hydrocarbon receptor/transcription factor-expressing stromal/adherent cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Apoptosis; B-Lymphocytes; Benzo(a)pyrene; Benzoflavones; Bone Marrow Cells; Cell Line; DNA Fragmentation; Flow Cytometry; Gene Expression Regulation; Hematopoiesis; Liver; Mice; Mice, Knockout; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; RNA, Messenger; Stromal Cells; Transcription Factors | 1999 |
Inhibitory activity of vitamin E and alpha-naphthoflavone on beta-carotene-enhanced transformation of BALB/c 3T3 cells by benzo(a)pyrene and cigarette-smoke condensate.
Topics: 3T3 Cells; Animals; Benzo(a)pyrene; Benzoflavones; beta Carotene; Biotransformation; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Drug Interactions; Humans; Mice; Nicotiana; Plants, Toxic; Smoke; Vitamin E | 2000 |
A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzofurans; beta-Naphthoflavone; Binding, Competitive; Carrier Proteins; Cytochrome P-450 CYP1A1; Cytosol; Female; Glycine N-Methyltransferase; Kinetics; Liver; Methylcholanthrene; Methyltransferases; Molecular Weight; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2000 |
Activity of benzo[a]pyrene and its hydroxylated metabolites in an estrogen receptor-alpha reporter gene assay.
Topics: Benzo(a)pyrene; Benzoflavones; beta-Galactosidase; Breast Neoplasms; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression; Genes, Reporter; Genetic Techniques; Humans; Hydroxylation; Luciferases; Receptors, Estrogen; Transfection; Tumor Cells, Cultured | 2000 |
Evaluation of benzo(a)pyrene-induced DNA damage in human endothelial cells using alkaline single cell gel electrophoresis.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens, Environmental; Cell Line; Comet Assay; Cytochrome P-450 CYP1A1; DNA Damage; Endothelium, Vascular; Female; Humans; Infant, Newborn; Mice; Mice, Inbred C57BL; Mutagens | 2000 |
The influence of diesel exhaust particles on mononuclear phagocytic cell-derived cytokines: IL-10, TGF-beta and IL-1 beta.
Topics: Adult; Benzo(a)pyrene; Benzoflavones; Bronchial Hyperreactivity; Carbon; Gene Expression; Humans; Hypersensitivity; In Vitro Techniques; Interleukin-1; Interleukin-10; Interleukin-4; Leukocytes, Mononuclear; Lipopolysaccharides; Lymphocytes; Macrophages; Middle Aged; Receptors, IgE; RNA, Messenger; Transforming Growth Factor beta; Vehicle Emissions | 2001 |
Epigenetics of breast cancer: polycyclic aromatic hydrocarbons as risk factors.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Benzo(a)pyrene; Benzoflavones; Blotting, Western; BRCA1 Protein; Breast Neoplasms; Carcinogens; DNA Damage; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Genes, BRCA1; Humans; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Human intestinal Caco-2 cells display active transport of benzo[a]pyrene metabolites.
Topics: Adenosine Triphosphate; Aryl Hydrocarbon Hydroxylases; ATP-Binding Cassette Transporters; Benzo(a)pyrene; Benzoflavones; Biological Transport, Active; Caco-2 Cells; Cell Polarity; Cyclosporine; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Enterocytes; Gene Expression; Humans; Models, Biological; Probenecid; Propionates; Quinolines; Verapamil; Vinblastine | 2003 |
Aryl hydrocarbon receptor ligands repress T-cadherin expression in vascular smooth muscle cells.
Topics: 5' Untranslated Regions; Amino Acid Sequence; Animals; Aorta; Benzo(a)pyrene; Benzoflavones; Cadherins; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Environmental Pollutants; Gene Expression Regulation; Humans; Ligands; Mice; Molecular Sequence Data; Muscle, Smooth, Vascular; Nucleic Acid Synthesis Inhibitors; Polychlorinated Dibenzodioxins; Protein Synthesis Inhibitors; Rats; Rats, Inbred WKY; Receptors, Aryl Hydrocarbon; RNA, Messenger; Sequence Alignment; Signal Transduction | 2003 |
Polycyclic aromatic hydrocarbons inhibit differentiation of human monocytes into macrophages.
Topics: Antigens, Surface; Benzo(a)pyrene; Benzoflavones; Biomarkers; Cell Adhesion; Cell Differentiation; Cells, Cultured; Down-Regulation; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Immunophenotyping; Immunosuppressive Agents; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon | 2003 |
Benzo[a]pyrene regulates osteoblast proliferation through an estrogen receptor-related cyclooxygenase-2 pathway.
Topics: Animals; Aspirin; Benzo(a)pyrene; Benzoflavones; Cell Division; Cells, Cultured; Cyclooxygenase 2; Enzyme Inhibitors; Humans; Isoenzymes; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphoinositide-3 Kinase Inhibitors; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Rats; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; Tamoxifen | 2004 |
Antiestrogenic effects of motorcycle exhaust particulate in MCF-7 human breast cancer cells and immature female rats.
Topics: Air Pollutants; Animals; Benzo(a)pyrene; Benzoflavones; Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Humans; Injections, Intraperitoneal; Motorcycles; Organ Size; Particle Size; Rats; Rats, Wistar; Receptors, Estrogen; Uterus; Vehicle Emissions | 2004 |
Intestinal metabolism of PAH: in vitro demonstration and study of its impact on PAH transfer through the intestinal epithelium.
Topics: Benzo(a)pyrene; Benzoflavones; Caco-2 Cells; Cell Differentiation; Cell Membrane Permeability; Cell Survival; Chromatography, Thin Layer; Colon; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Histocytochemistry; Humans; Intestinal Absorption; Intestinal Mucosa; Isoenzymes; Ketoconazole; Kinetics; Phenanthrenes; Pyrenes | 2005 |
Involvement of endogenous nitric oxide in myeloperoxidase mediated benzo(a)pyrene induced polymorphonuclear leukocytes injury.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Catalase; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutathione Transferase; Guanidines; Male; Neutrophils; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peroxidase; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase | 2006 |
Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor.
Topics: Animals; Aromatase; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzo(a)pyrene; Benzoflavones; Cell Line; Estradiol; Fulvestrant; Gene Expression Regulation, Enzymologic; Humans; Immunohistochemistry; Larva; Ligands; Luciferases; Neuroglia; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; Receptors, Estrogen; RNA, Messenger; Transcription Factors; Zebrafish; Zebrafish Proteins | 2007 |
Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Basic Helix-Loop-Helix Transcription Factors; Benzo(a)pyrene; Benzoflavones; Carcinogens; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Down-Regulation; Ellipticines; Enzyme Induction; Enzyme Inhibitors; Liver Neoplasms, Experimental; Mice; Phosphorylation; Receptors, Aryl Hydrocarbon; Tumor Suppressor Protein p53 | 2007 |
Suppression of T lymphocyte proliferation to antigenic and mitogenic stimuli by Benzo(alpha)pyrene and 2-aminofluorene metabolites.
Topics: Acetyl Coenzyme A; Animals; Antigens; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Carcinogens; Cell Proliferation; Cells, Cultured; Concanavalin A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA Adducts; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorenes; Immunosuppressive Agents; Interleukin-2; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred C3H; Mitogens; Spleen; T-Lymphocytes | 2007 |
Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes.
Topics: Benzo(a)pyrene; Benzoflavones; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Glutathione Transferase; Humans; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mutagenicity Tests; Polychlorinated Biphenyls | 2009 |
Hepatic and vascular mRNA expression in adult zebrafish (Danio rerio) following exposure to benzo-a-pyrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 Enzyme System; Gene Expression Regulation; Liver; Mesenteric Arteries; Polychlorinated Dibenzodioxins; Prostaglandin-Endoperoxide Synthases; Receptors, Aryl Hydrocarbon; Resveratrol; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stilbenes; Zebrafish | 2009 |
Extractable organic matter of standard reference material 1649a influences immunological response induced by pathogen-associated molecular patterns.
Topics: Air Pollutants; Benzo(a)pyrene; Benzoflavones; Bronchi; Cell Line; Cytokines; Humans; Interleukin-6; Interleukin-8; Particulate Matter; Poly C; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; Reference Standards; Respiratory Mucosa; Transforming Growth Factor beta | 2010 |
Aryl hydrocarbon receptor-independent up-regulation of intracellular calcium concentration by environmental polycyclic aromatic hydrocarbons in human endothelial HMEC-1 cells.
Topics: Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Calcium; Cell Line; Cytochrome P-450 Enzyme System; Endothelial Cells; Environmental Pollution; Gene Knockdown Techniques; Humans; Receptors, Aryl Hydrocarbon; RNA, Small Interfering; Up-Regulation | 2012 |
The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy.
Topics: Animals; Antibodies, Monoclonal; B7-H1 Antigen; Benzo(a)pyrene; Benzoflavones; Carcinogens; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Nicotiana; Receptors, Aryl Hydrocarbon; Signal Transduction; Small Cell Lung Carcinoma; Smoking; Survival Analysis; Xenograft Model Antitumor Assays | 2019 |
Exposure of Physalaemus cuvieri (Anura) to benzo[a]pyrene and α-naphthoflavone: Morphofunctional effects on hepatic melanomacrophages and erythrocytes abnormalities.
Topics: Animals; Anura; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 CYP1A1; Erythrocytes | 2021 |