alpha-naphthoflavone has been researched along with 3-methylcholanthrene in 63 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (53.97) | 18.7374 |
| 1990's | 14 (22.22) | 18.2507 |
| 2000's | 10 (15.87) | 29.6817 |
| 2010's | 4 (6.35) | 24.3611 |
| 2020's | 1 (1.59) | 2.80 |
| Authors | Studies |
|---|---|
| Carazo, A; Drechslerová, M; Hrušková, ZR; Hyrsova, L; Kuneš, J; Nova, A; Pavek, P; Pour, M; Smutny, T; Špulák, M | 1 |
| Giri, SN; Siegel, DM | 1 |
| Guyda, HJ | 1 |
| Haraguchi, K; Hirohata, T; Kiyohara, C; Masuda, Y; Mohri, N | 1 |
| Blaich, G; Cikryt, P; Göttlicher, M; Metzler, M | 1 |
| Antignac, E; Cassand, P; Grolier, P; Koch, B; Narbonne, JF | 1 |
| Blaich, G; Metzler, M; Raabe, H | 1 |
| Guengerich, FP; Shimada, T; Shimura, H; Tanaka, R; Yamazaki, H | 1 |
| Crouch, LS; Ebel, RE | 1 |
| Juchau, MR; Namkung, MJ; Yang, HY | 1 |
| Blumer, JL; Frank, DM | 1 |
| Mattison, DR; Shiromizu, K | 1 |
| Bender, PE; Eckardt, RD; Leonard, TB; Newton, JF; Romano, MC; Straub, KM | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Koda, A; Konishi, Y; Mori, Y; Nagai, H; Toyoshi, K; Yamazaki, H | 1 |
| Fukuhara, M; Ohno, Y; Sunouchi, M; Takanaka, A | 1 |
| Emi, Y; Omura, T | 1 |
| Gessner, T; Olson, JR; Wroblewski, VJ | 1 |
| Boobis, AR; Davies, DS; Whyte, C | 1 |
| Bogdanffy, MS; Brown, DR; Roberts, AE; Schatz, RA | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Haaf, H; Metzler, M | 1 |
| Melius, P; Swain, L | 1 |
| Miyauchi, M | 1 |
| Kamataki, T; Kato, R; Mita, S; Yamazoe, Y | 1 |
| Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
| Boutwell, RK; Conrad, EA; Verma, AK | 1 |
| Nagata, K; Yoshihara, S; Yoshimura, H | 1 |
| Gielen, JE; Kremers, P; Pasleau, F | 1 |
| Cazer, FD; Hart, RW; Sheikh, YM; Witiak, DT | 1 |
| Kamei, H | 1 |
| DePierre, JW; Meijer, J | 1 |
| Bryant, BJ; Easterling, R; Nesnow, S; Rudo, K | 1 |
| Highet, RJ; Jerina, DM; Levin, W; Ryan, DE; Shibata, T; Thomas, PE; Vyas, KP; Yeh, HJ | 1 |
| Nesnow, S | 1 |
| Borm, PJ; Frankhuijzen-Sierevogel, A; Noordhoek, J | 1 |
| Burke, MD; Lees, GM; Murray, GI | 1 |
| Coombs, MM | 1 |
| Belvedere, G; Coon, MJ; Gelboin, HV; Miller, H; Vatsis, KP | 1 |
| Hiraga, K; Kawano, S; Kojima, A | 1 |
| Alworth, WL; Viswanathan, T | 1 |
| Grafstöm, R; Stohs, SJ | 1 |
| Masuda, Y; Nagayama, J | 2 |
| Hirohata, T; Kiyohara, C | 1 |
| Ichikawa, Y; Ohnishi, T; Okuyama, E; Tomita, S | 1 |
| Dhawan, A; Parmar, D; Seth, PK | 1 |
| Burchiel, SW; Lane, J; Lauer, FT; Tannheimer, SL | 1 |
| Kvasnicková, E; Skálová, L; Szotáková, B; Wsól, V | 1 |
| Brauze, D; Malejka-Giganti, D | 1 |
| Arinç, E; Sen, A | 1 |
| Dayal, M; Dey, A; Dhawan, A; Parmar, D; Seth, PK | 1 |
| Dusatti, F; Ferro, M; Gelardi, A; Morini, F; Penco, S | 1 |
| Hayashi, S; Komura, K; Makino, I; Poellinger, L; Tanaka, H | 1 |
| Audus, KL; Avery, ML; Meek, CE | 1 |
| Ishii, Y; Mori, MA; Naito, E; Oguri, K; Taura, K; Yamada, H | 1 |
| Deschaux, P; Duchiron, C; Reynaud, S | 1 |
| Deschaux, P; Reynaud, S | 1 |
| Riddick, DS; Sawaya, RM | 1 |
| Anderson, K; Cooper, JM; Haswell, SJ; Marshall, D; Yin, H; Zhang, X | 1 |
| Faletti, AG; Galarza, RA; Lomniczi, A; Rhon-Calderón, EA | 1 |
| Faletti, AG; Galarza, RA; Lomniczi, A; Rhon-Calderón, EA; Toro, CA | 1 |
| Faletti, AG; Galarza, RA; Rhon Calderón, EA | 1 |
63 other study(ies) available for alpha-naphthoflavone and 3-methylcholanthrene
| Article | Year |
|---|---|
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Topics: Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hep G2 Cells; Hepatocytes; Humans; Models, Molecular; Molecular Structure; Quinazolines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship | 2016 |
Characterization of covalent binding of [14C]-2-chloro-4-acetotoluidide to microsomes of starling liver and kidney.
Topics: Animals; Benzoflavones; Birds; Cysteine; Cytochrome P-450 Enzyme Inhibitors; Glutathione; In Vitro Techniques; Kidney; Kinetics; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Protein Binding; Sulfhydryl Compounds; Toluidines | 1991 |
Metabolic effects of growth factors and polycyclic aromatic hydrocarbons on cultured human placental cells of early and late gestation.
Topics: Aminoisobutyric Acids; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; ErbB Receptors; Female; Gestational Age; Humans; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Methylcholanthrene; Placenta; Polycyclic Compounds; Pregnancy; Thymidine; Time Factors; Tritium | 1991 |
In vitro effects of methylsulfonyl polychlorinated biphenyls and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity in human lymphoblastoid cells.
Topics: Aryl Hydrocarbon Hydroxylases; Benzoflavones; Enzyme Induction; Flavonoids; Humans; Lymphocytes; Methylcholanthrene; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Sulfones | 1990 |
Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male Syrian golden hamster liver.
Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Cytochrome P-450 Enzyme System; Cytochromes b5; Diethylstilbestrol; Drug Interactions; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1990 |
Prochloraz as potent inhibitor of benzo[a]pyrene metabolism and mutagenic activity in rat liver fractions.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Fungicides, Industrial; Imidazoles; Liver; Male; Methylcholanthrene; Miconazole; Mutagenicity Tests; Rats; Rats, Inbred Strains | 1990 |
Modification of 7,8-benzoflavone metabolism in hamster liver and kidney microsomes by hepatic tumor inducing treatments.
Topics: Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Diethylstilbestrol; Flavonoids; Kidney; Liver Neoplasms; Male; Mesocricetus; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Reference Values | 1990 |
Metabolic deactivation of furylfuramide by cytochrome P450 in human and rat liver microsomes.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Furylfuramide; Humans; Inactivation, Metabolic; Kinetics; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Neoplasms; Nitrofurans; Phenobarbital; Rats; Reference Values; Salmonella typhimurium; Spectrophotometry | 1990 |
Influence of chlordecone and mirex exposure on benzo[a]pyrene metabolism of rat-liver microsomes.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Chlordecone; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Insecticides; Liver; Methylcholanthrene; Microsomes, Liver; Mirex; Pesticide Residues; Phenobarbital; Rats; Subcellular Fractions | 1987 |
Immunodetection, immunoinhibition, immunoquantitation and biochemical analyses of cytochrome P-450IA1 in tissues of the ratoffceptus during the progression of organogenesis.
Topics: 2-Acetylaminofluorene; Amnion; Animals; Benzo(a)pyrene; Benzoflavones; Chorion; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Enzyme Induction; Female; Gestational Age; Immunologic Techniques; Isoenzymes; Methylcholanthrene; Metyrapone; Morphogenesis; Oxazines; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Yolk Sac | 1989 |
Alteration of methylcholanthrene-mediated suppression of cutaneous delayed hypersensitivity by benzoflavone treatment of C57BL/6J mice.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dinitrofluorobenzene; Dose-Response Relationship, Drug; Drug Hypersensitivity; Enzyme Induction; Female; Flavonoids; Hypersensitivity, Delayed; Immunosuppressive Agents; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Phenobarbital; Polycyclic Compounds; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1988 |
Murine oocyte destruction following intraovarian treatment with 3-methylcholanthrene or 7,12-dimethylbenz(a)anthracene: protection by alpha-naphthoflavone.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Female; Flavonoids; Functional Laterality; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Oocytes; Ovary | 1985 |
Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Pyrimidines; Rats; Rats, Inbred F344; Temperature | 1987 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction.
Topics: Adult; Aniline Hydroxylase; Animals; Benzoflavones; Biotransformation; Carcinogens; Cricetinae; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; DNA; Dose-Response Relationship, Drug; Female; Humans; Liver; Macaca fascicularis; Macaca mulatta; Male; Mesocricetus; Methylation; Methylcholanthrene; Metyrapone; Mice; Mice, Inbred Strains; Mutagens; Nitrosamines; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity | 1986 |
Effects of various inducers on the activities of cytochrome P-450-mixed function oxidases and aflatoxin B1 activation in microsomes of hamster livers.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Cricetinae; DNA; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidoreductases | 1988 |
Synthesis of sex-specific forms of cytochrome P-450 in rat liver is transiently suppressed by hepatic monooxygenase inducers.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Female; Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Rats, Inbred Strains; Reference Values; Sex Factors | 1988 |
Qualitative and quantitative differences in the induction and inhibition of hepatic benzo[a]pyrene metabolism in the rat and hamster.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Cricetinae; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Rats, Inbred Strains; Safrole; Species Specificity | 1988 |
Selective induction and inhibition of the components of 7-ethoxycoumarin O-deethylase activity in the rat.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Regioselective inhibition of benzo(a)pyrene metabolism by corticosterone in comparison with metyrapone and alpha-naphthoflavone.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Chromatography, High Pressure Liquid; Corticosterone; Cytochrome P-450 Enzyme System; Drug Interactions; Flavonoids; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver; Pentobarbital; Pyridines; Rats; Rats, Inbred Strains | 1986 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
In vitro metabolism of diethylstilbestrol by hepatic, renal and uterine microsomes of rats and hamsters. Effects of different inducers.
Topics: Animals; Benzoflavones; Biotransformation; Chromatography, High Pressure Liquid; Cricetinae; Diethylstilbestrol; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Kidney; Male; Mass Spectrometry; Mesocricetus; Methylcholanthrene; Microsomes; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Uterus | 1985 |
Characterization of benzo[a]pyrene metabolites formed by 3-methylcholanthrene-induced goldfish, black bullhead and brown bullhead.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Chromatography, High Pressure Liquid; Fishes; Goldfish; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Polycyclic Compounds; Rats; Rats, Inbred Strains; Trichloroepoxypropane | 1984 |
Conversion of procarcinogens to mutagens by the S-9 fraction from the liver of rainbow trout (Salmo gairdneri): inducibility with PCB, 3-methylcholanthrene and phenobarbital and inhibition by metyrapone and alpha-naphthoflavone.
Topics: 2-Acetylaminofluorene; Animals; Anthracenes; Benzo(a)pyrene; Benzoflavones; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Liver; Methylcholanthrene; Metyrapone; Mutagenicity Tests; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Salmonidae; Subcellular Fractions; Temperature; Trout | 1984 |
Metabolic activation of Trp-P-2, a tryptophan-pyrolysis mutagen, by isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Biotransformation; Carbolines; Cysteine; DNA; Indoles; Liver; Male; Maleates; Methylcholanthrene; Mutagens; Proteins; Rats; Rats, Inbred Strains; RNA | 1983 |
Nature of N-nitrosodimethylamine demethylase in hepatic microsomes of rats.
Topics: Aminoacetonitrile; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imidazoles; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Monoamine Oxidase; Niacinamide; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Tranylcypromine | 1984 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
Different responsiveness of hepatic and pulmonary microsomal mixed function oxidases to phenobarbital-type and 3-methylcholanthrene-type polychlorinated biphenyls in rats.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Enzyme Induction; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Competition between benzo[a]pyrene and various steroids for cytochrome P-450-dependent rat liver monooxygenases.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; Benzopyrenes; Binding, Competitive; Cytochrome P-450 Enzyme System; Dehydroepiandrosterone; Enzyme Induction; Female; Liver; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pregnanolone; Progesterone; Rats; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Substrate Specificity; Testosterone | 1981 |
Biotransformation of 7, 12-dimethylbenz(a)anthracene(DMBA): on the genesis of DMBA-trans-dihydrodiols and DMBA-7- and 12-methylhydroxylated metabolites.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Carbon Disulfide; Flavonoids; Liver; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Phenobarbital; Proadifen; Rats; Structure-Activity Relationship | 1980 |
Effect of carcinogenic polycyclic aromatic hydrocarbons on mouse embryonic cells in culture: induction of spindle-shaped cells.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzoflavones; Benzopyrenes; Carcinogens; Cell Survival; Cells, Cultured; Embryo, Mammalian; Fibroblasts; Methylcholanthrene; Mice; Polycyclic Compounds | 1980 |
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone | 1983 |
Reanalysis and clarification of the structures of alpha-naphthoflavone dihydrodiols formed by uninduced and induced rat liver microsomes from Charles River CD and Sprague-Dawley rats.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity | 1983 |
Metabolism of alpha-naphthoflavone and beta-naphthoflavone by rat liver microsomes and highly purified reconstituted cytochrome P-450 systems.
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Flavonoids; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry, Ultraviolet | 1983 |
Multiple effects and metabolism of alpha-naphthoflavone in induced and uninduced hepatic microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzopyrene Hydroxylase; beta-Naphthoflavone; Cricetinae; Cytochrome P-450 Enzyme System; Flavonoids; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Rats; Species Specificity | 1983 |
Kinetics of in vitro O-deethylation of phenacetin and 7-ethoxycoumarin by rat intestinal mucosal cells and microsomes. The effect of induction with 3-methylcholanthrene and inhibition with alpha-naphthoflavone.
Topics: Animals; Benzoflavones; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Flavonoids; Humans; Intestinal Mucosa; Kinetics; Male; Methylcholanthrene; Mice; Microsomes; Phenacetin; Rats; Rats, Inbred Strains | 1983 |
Fluorescence-microscopic measurement of intracellular cytochrome P-450 enzyme activity (ethoxyresorufin O-de-ethylation) in unfixed liver section.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; In Vitro Techniques; Intracellular Fluid; Kinetics; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Oxazines; Salicylamides | 1983 |
The influence of various enzyme inducers on the microsomal metabolism of 7,8-benzoflavone.
Topics: Animals; Aroclors; Benzoflavones; Chlorodiphenyl (54% Chlorine); Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Flavonoids; Male; Mass Spectrometry; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
Hydroxylation of benzo[a]pyrene and binding of (-)trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene metabolites to deoxyribonucleic acid catalyzed by purified forms of rabbit liver microsomal cytochrome P-450. Effect of 7,8-benzoflavone, butylated hydroxytolu
Topics: Animals; Ascorbic Acid; Benzoflavones; Benzopyrenes; Butylated Hydroxytoluene; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Rabbits | 1980 |
The suppressive effect of hepatic 9,000 x G supernatant fraction from 3-methylcholanthrene-treated rats on the mutagenic activity of 2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Animals; Benzoflavones; Drug Synergism; Flavonoids; Liver; Male; Methylcholanthrene; Mutagens; Phenobarbital; Rats; Subcellular Fractions | 1980 |
Effects of 1-arylpyrroles and naphthoflavones upon cytochrome P-450 dependent monooxygenase activities.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Female; Flavonoids; In Vitro Techniques; Kinetics; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pyrroles; Rats | 1981 |
Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells.
Topics: Animals; Benzoflavones; Benzopyrenes; Coumarins; Cytochrome P-450 CYP1A1; Female; Intestine, Small; Methylcholanthrene; Metyrapone; Microsomes; Oxidoreductases; Proadifen; Rats; Rats, Inbred Strains; Rotenone | 1981 |
Effects of 3-methylsulphonyl-4,5,3',4',-tetrachlorobiphenyl and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activities of murine hepatic microsomes prepared from inbred strains with different Ah responsiveness.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cytochrome P-450 Enzyme System; In Vitro Techniques; Methylcholanthrene; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Microsomes, Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins; Stimulation, Chemical | 1993 |
Effects of methylsulphonyl polychlorinated biphenyl homologues and 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Cells, Cultured; Enzyme Induction; Humans; In Vitro Techniques; Lymphocytes; Methylcholanthrene; Mice; Mice, Inbred AKR; Mice, Inbred BALB C; Microsomes, Liver; Polychlorinated Biphenyls; Polychlorinated Dibenzodioxins | 1993 |
In vivo effect of 7,8-benzoflavone on aryl hydrocarbon hydroxylase activity of mouse liver microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Enzyme Induction; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Polychlorinated Dibenzodioxins | 1993 |
Characteristic properties of a retinoic acid synthetic cytochrome P-450 purified from liver microsomes of 3-methylcholanthrene-induced rats.
Topics: Acyclic Monoterpenes; Animals; Antibodies; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Immunoglobulin G; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Monoterpenes; Rats; Rats, Sprague-Dawley; Retinaldehyde; Sequence Analysis; Terpenes; Tretinoin; Xenobiotics | 1996 |
Evidence for O-dealkylation of 7-pentoxyresorufin by cytochrome P450 2B1/2B2 isoenzymes in brain.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Brain; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Dealkylation; Immunoglobulin G; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Metyrapone; Oxazines; Phenobarbital; Rats; Rats, Wistar; Steroid Hydroxylases | 1998 |
Factors influencing elevation of intracellular Ca2+ in the MCF-10A human mammary epithelial cell line by carcinogenic polycyclic aromatic hydrocarbons.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetylcysteine; Aryl Hydrocarbon Receptor Nuclear Translocator; Benzoflavones; Benzopyrenes; Breast; Calcium; Carcinogens; Cell Line; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; DNA-Binding Proteins; Egtazic Acid; Epithelial Cells; Humans; Methylcholanthrene; Polychlorinated Dibenzodioxins; Polycyclic Aromatic Hydrocarbons; Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription Factors | 1999 |
Role of cytochrome P4501A in biotransformation of the potential anticancer drug oracin.
Topics: Aniline Hydroxylase; Animals; Antineoplastic Agents; Benzoflavones; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethanolamines; Isoquinolines; Male; Methylcholanthrene; Microsomes, Liver; Rats; Rats, Wistar | 1999 |
A novel 4 S [3H]beta-naphthoflavone-binding protein in liver cytosol of female Sprague-Dawley rats treated with aryl hydrocarbon receptor agonists.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzofurans; beta-Naphthoflavone; Binding, Competitive; Carrier Proteins; Cytochrome P-450 CYP1A1; Cytosol; Female; Glycine N-Methyltransferase; Kinetics; Liver; Methylcholanthrene; Methyltransferases; Molecular Weight; Polychlorinated Dibenzodioxins; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2000 |
Further immunochemical and biocatalytic characterization of CYP1A1 from feral leaping mullet liver (Liza saliens) microsomes.
Topics: Animals; Benzoflavones; Carcinogens; Catalysis; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Perciformes; Rats | 2000 |
Cytochrome P450 1A1 (CYP1A1) in blood lymphocytes evidence for catalytic activity and mRNA expression.
Topics: Animals; Antibodies; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Carcinogens; Catalysis; Cytochrome P-450 CYP1A1; Enzyme Induction; Isoenzymes; Lymphocytes; Male; Methylcholanthrene; Microsomes, Liver; Oxazines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Induction by xenobiotics of phase I and phase II enzyme activities in the human keratinocyte cell line NCTC 2544.
Topics: Benzoflavones; beta-Naphthoflavone; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Inactivation, Metabolic; Keratinocytes; Methylcholanthrene; Metyrapone; Oxidoreductases; Phenobarbital; Xenobiotics | 2001 |
Aryl hydrocarbon receptor/dioxin receptor in human monocytes and macrophages.
Topics: Benzoflavones; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Cytochrome P-450 CYP1A1; DNA; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Immunoblotting; Ligands; Luciferases; Macrophages; Methylcholanthrene; Monocytes; Polychlorinated Dibenzodioxins; Protein Binding; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subcellular Fractions; Transcription, Genetic; Transfection; U937 Cells | 2001 |
The presence of inducible cytochrome P450 types 1A1 and 1A2 in the BeWo cell line.
Topics: Benz(a)Anthracenes; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Humans; Inhibitory Concentration 50; Methylcholanthrene; Microsomes, Liver; Smoking; Theophylline; Trophoblasts; Tumor Cells, Cultured | 2003 |
Cytochrome P450 1A1 (CYP1A1) inhibitor alpha-naphthoflavone interferes with UDP-glucuronosyltransferase (UGT) activity in intact but not in permeabilized hepatic microsomes from 3-methylcholanthrene-treated rats: possible involvement of UGT-P450 interacti
Topics: Animals; Benzoflavones; Cytochrome P-450 CYP1A1; Enzyme Inhibitors; Glucuronosyltransferase; In Vitro Techniques; Kinetics; Methylcholanthrene; Microsomes, Liver; Permeability; Rats | 2004 |
3-Methylcholanthrene induces lymphocyte and phagocyte apoptosis in common carp (Cyprinus carpio L) in vitro.
Topics: Animals; Apoptosis; Benz(a)Anthracenes; Benzoflavones; Calcium; Carps; Cell Size; Chromatin; Flow Cytometry; Lymphocytes; Methylcholanthrene; Microscopy, Fluorescence; Phagocytes; Phosphatidylserines; Toxicity Tests, Acute; Water Pollutants, Chemical | 2004 |
The effects of 3-methylcholanthrene on lymphocyte proliferation in the common carp (Cyprinus carpio L.).
Topics: Animals; Benzoflavones; Carps; Cell Proliferation; Cell Separation; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Immunity, Cellular; Injections, Intraperitoneal; Liver; Lymphocytes; Methylcholanthrene; Microsomes; Mitogens; Receptors, Aryl Hydrocarbon; Subcellular Fractions | 2005 |
Cytochrome P450 2C11 5'-flanking region and promoter: regulation by aromatic hydrocarbons in vitro.
Topics: 5' Flanking Region; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carcinoma, Hepatocellular; Cell Line, Tumor; Cloning, Molecular; Cytochrome P450 Family 2; Enzyme Induction; Gene Expression Regulation, Enzymologic; Humans; Liver Neoplasms; Luciferases; Methylcholanthrene; Mice; Mutagenesis, Site-Directed; Polychlorinated Dibenzodioxins; Promoter Regions, Genetic; Rats; Receptors, Aryl Hydrocarbon; RNA, Messenger; Steroid 16-alpha-Hydroxylase | 2008 |
Microfluidic-based measurements of cytochrome P450 enzyme activity of primary mammalian hepatocytes.
Topics: Animals; Benzoflavones; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hepatocytes; Methylcholanthrene; Microfluidic Analytical Techniques; Oxazines; Rats; Spectrometry, Fluorescence | 2010 |
The systemic and gonadal toxicity of 3-methylcholanthrene is prevented by daily administration of α-naphthoflavone.
Topics: Animals; Benzoflavones; Bone Marrow Cells; Chromatin Immunoprecipitation; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Methylcholanthrene; Oocytes; Ovarian Follicle; Ovulation; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon | 2016 |
Changes in the expression of genes involved in the ovarian function of rats caused by daily exposure to 3-methylcholanthrene and their prevention by α-naphthoflavone.
Topics: Acetylation; Animals; Benzoflavones; Chromatin Immunoprecipitation; Down-Regulation; Epigenesis, Genetic; Female; Histones; Methylation; Methylcholanthrene; Ovarian Follicle; Promoter Regions, Genetic; Protein Binding; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon; Up-Regulation | 2018 |
3-Methylcholanthrene impacts on the female germ cells of rats without causing systemic toxicity.
Topics: Animals; Apoptosis; Benzoflavones; Bone Marrow Cells; DNA Damage; Dose-Response Relationship, Drug; Environmental Pollutants; Female; Meiosis; Methylcholanthrene; Oocytes; Ovarian Follicle; Rats; Rats, Sprague-Dawley | 2020 |