Compounds > alpha-methylene gamma-butyrolactone
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alpha-methylene gamma-butyrolactone and parthenolide

alpha-methylene gamma-butyrolactone has been researched along with parthenolide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Chen, Y; Ding, Y; Fan, H; Gao, Y; Han, B; Ji, Q; Jia, Y; Li, D; Li, LY; Li, Q; Lin, J; Long, J; Lu, Y; Ma, W; Ma, X; Qiu, C; Shi, Q; Shi, Y; Tong, Z; Yang, M; Zhai, J; Zhang, H; Zhang, J; Zhang, Q; Zhang, W1
Gagare, PD; Helppi, MA; Nair, HN; Nicponski, DR; Ramachandran, PV; Schmidt, CM; Yip-Schneider, MT1
An, T; Cai, B; Chen, L; Duan, A; Ju, X; Kong, L; Li, X; Li, Y; Yang, Q1
Contreras, JI; Karpf, AR; Kizhake, S; Kour, S; Natarajan, A; Rana, S; Robb, CM; Sonawane, YA; Zahid, M1

Other Studies

4 other study(ies) available for alpha-methylene gamma-butyrolactone and parthenolide

ArticleYear
Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Lactones; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Prodrugs; Sesquiterpenes; Sesquiterpenes, Guaiane; Structure-Activity Relationship; Transplantation, Heterologous

2012
Synthetic α-(aminomethyl)-γ-butyrolactones and their anti-pancreatic cancer activities.
    Bioorganic & medicinal chemistry letters, 2013, Dec-15, Volume: 23, Issue:24

    Topics: 4-Butyrolactone; Amination; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Pancreatic Neoplasms; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship

2013
Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth.
    The Journal of biological chemistry, 2020, 03-13, Volume: 295, Issue:11

    Topics: 4-Butyrolactone; Apoptosis; beta Catenin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Proteolysis; Sesquiterpenes; Ubiquitin-Specific Peptidase 7; Ubiquitination; Wnt Signaling Pathway

2020
Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.
    Chemical biology & drug design, 2020, Volume: 96, Issue:2

    Topics: 4-Butyrolactone; Amines; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinases; Drug Screening Assays, Antitumor; Female; Humans; Molecular Targeted Therapy; NF-kappa B; Ovarian Neoplasms; Piperazines; Piperidines; Prodrugs; Protein Kinase Inhibitors; Pyrazoles; Pyridines; Sesquiterpenes; Signal Transduction; Structure-Activity Relationship

2020