alpha-methyldopamine has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hsu, FL; Yeh, SY | 1 |
| Bourquin, D; Bracher, K; Brenneisen, R; Helmlin, HJ; Vonlanthen, D | 1 |
| Easton, N; Fry, J; Kingston, S; Marsden, CA; O'Shea, E; Watkins, A | 1 |
| Bastos, ML; Borges, F; Carvalho, F; Carvalho, M; Fernandes, E; Milhazes, N; Remião, F | 1 |
| Bastos, Mde L; Boer, Dd; Branco, PS; Brulport, M; Carmo, H; Carvalho, F; Doehmer, J; Ferreira, LM; Hengstler, JG; Hermes, M; Krebsfaenger, N; Oesch, F; Remião, F; Schön, MR; Silva, R | 1 |
| Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Dirnagl, U; Fernandes, E; Ferreira, LM; Lobo, AM; Macedo, C; Meisel, A; Remião, F | 1 |
| Carvalho, F; Lucchesi, PA; Shenouda, SK; Varner, KJ | 1 |
| Abad, S; Camarasa, J; Escubedo, E; Pubill, D; Torres, I | 1 |
| Largeron, M; Martinez, CM; Neudörffer, A | 1 |
| Carmo, H; Carvalho, F; da Silva, DD; Silva, E | 1 |
| Barbosa, DJ; Bastos, Mde L; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R; Vilas-Boas, V | 1 |
| Barbosa, DJ; Bastos, ML; Branco, PS; Capela, JP; Carvalho, F; Fernandes, E; Ferreira, LM; Silva, R | 1 |
| Maurer, HH; Meyer, MR; Richter, LH | 1 |
1 trial(s) available for alpha-methyldopamine and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
Analysis of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS.
Topics: 3,4-Methylenedioxyamphetamine; Administration, Oral; Adolescent; Adult; Chromatography, High Pressure Liquid; Deoxyepinephrine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Hallucinogens; Humans; Hydrolysis; Ion Exchange Resins; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Reference Standards | 1996 |
12 other study(ies) available for alpha-methyldopamine and n-methyl-3,4-methylenedioxyamphetamine
| Article | Year |
|---|---|
The neurochemical and stimulatory effects of putative metabolites of 3,4-methylenedioxyamphetamine and 3,4-methylenedioxymethamphetamine in rats.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain Chemistry; Central Nervous System Stimulants; Cerebral Cortex; Deoxyepinephrine; Dopamine; Epinephrine; Hydroxyindoleacetic Acid; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nordefrin; Rats; Rats, Inbred Strains; Serotonin | 1991 |
Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy).
Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Cytochrome P-450 CYP2D6; Deoxyepinephrine; Female; Glutathione; Humans; Male; Microsomes, Liver; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2003 |
The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine.
Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Antioxidants; Ascorbic Acid; Cell Separation; Cell Survival; Chromatography, High Pressure Liquid; Deoxyepinephrine; Free Radical Scavengers; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hallucinogens; Hepatocytes; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Spectrophotometry, Ultraviolet | 2004 |
Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Topics: Alleles; Animals; Catalysis; Cell Line; Cricetinae; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dose-Response Relationship, Drug; Hallucinogens; Models, Biological; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Polymorphism, Genetic | 2006 |
Neurotoxicity mechanisms of thioether ecstasy metabolites.
Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Adenosine Triphosphate; Animals; Caspase 3; Cell Death; Cells, Cultured; Cerebral Cortex; Deoxyepinephrine; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Free Radical Scavengers; Glutathione; Hallucinogens; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Rats; Rats, Wistar; Temperature; Time Factors | 2007 |
Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.
Topics: Acetylcysteine; Animals; Antioxidants; Calcium Signaling; Cells, Cultured; Deoxyepinephrine; Dose-Response Relationship, Drug; Glutathione; Heart Ventricles; Male; Myocardial Contraction; Myocytes, Cardiac; N-Methyl-3,4-methylenedioxyamphetamine; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Time Factors | 2009 |
Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.
Topics: Animals; Cell Membrane; Cell Survival; Cocaine; Deoxyepinephrine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Paroxetine; PC12 Cells; Protein Conformation; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synaptosomes | 2011 |
A convenient biomimetic synthesis of optically active putative neurotoxic metabolites of MDMA ("ecstasy") from R-(-)- and S-(+)-N-methyl-α-methyldopamine precursors.
Topics: Biomimetic Materials; Deoxyepinephrine; Molecular Conformation; N-Methyl-3,4-methylenedioxyamphetamine; Optical Phenomena; Stereoisomerism | 2012 |
Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations.
Topics: 3,4-Methylenedioxyamphetamine; Biotransformation; Cell Survival; Chemical and Drug Induced Liver Injury; Deoxyepinephrine; Dose-Response Relationship, Drug; Hep G2 Cells; Hepatocytes; Humans; N-Methyl-3,4-methylenedioxyamphetamine; Nonlinear Dynamics; Risk Assessment; Temperature; Time Factors | 2014 |
The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations.
Topics: Acetylcysteine; Calcium; Caspase 3; Cell Differentiation; Cell Line; Deoxyepinephrine; Dopamine; Dopaminergic Neurons; Dose-Response Relationship, Drug; Glutathione; Humans; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Reactive Oxygen Species | 2014 |
"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.
Topics: 3,4-Methylenedioxyamphetamine; Acetylcysteine; Caspase 3; Cell Death; Cell Differentiation; Cell Line; Deoxyepinephrine; Fever; Glutathione; Humans; Mitochondria; N-Methyl-3,4-methylenedioxyamphetamine; Neurons; Neurotoxicity Syndromes; Temperature | 2014 |
Methylenedioxy designer drugs: mass spectrometric characterization of their glutathione conjugates by means of liquid chromatography-high-resolution mass spectrometry/mass spectrometry and studies on their glutathionyl transferase inhibition potency.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Deoxyepinephrine; Dinitrochlorobenzene; Enzyme Assays; Female; Glutathione; Glutathione Transferase; Humans; Isomerism; N-Methyl-3,4-methylenedioxyamphetamine; Placenta; Pregnancy; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry | 2014 |