Compounds > alpha-methyl-beta-hydroxybutyrate
Page last updated: 2024-09-04

alpha-methyl-beta-hydroxybutyrate and glycine

alpha-methyl-beta-hydroxybutyrate has been researched along with glycine in 12 studies

Compound Research Comparison

Studies
(alpha-methyl-beta-hydroxybutyrate)		Trials
(alpha-methyl-beta-hydroxybutyrate)		Recent Studies (post-2010)
(alpha-methyl-beta-hydroxybutyrate)		Studies
(glycine)		Trials
(glycine)		Recent Studies (post-2010) (glycine)
230535,1637568,415

Protein Interaction Comparison

ProteinTaxonomyalpha-methyl-beta-hydroxybutyrate (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's1 (8.33)18.2507
2000's2 (16.67)29.6817
2010's3 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Céspedes, C; Estrada, Y; Loria, AR; Nyhan, WL; Sweetman, L; Weyler, W1
Aramaki, S; Lehotay, D; Middleton, B; Nyhan, WL; Sweetman, L; Winter, SC1
Leonard, JV; Middleton, B; Seakins, JW1
Bartlett, K; Cannon, RA; Conde, C; Gomez Vazquez, J; Lipson, M; Middleton, B; Nyhan, WL; Romanos, A; Sweetman, L1
Bennett, MJ; Littlewood, JM; MacDonald, A; Pollitt, RJ; Thompson, J1
Condado, I; DelValle, JA; Garcia, MJ; Jiménez, A; López, O; Merinero, B; Solaguren, R; Ugarte, M1
Middleton, B; Oorthuys, JW; Schutgens, RB; Tegelaers, WH; vd Blij, JF; Veder, HA; Vulsma, T1
da C Ferreira, G; Dalcin, KB; de Assis, DR; Filho, CS; Latini, A; Leipnitz, G; Maria, RC; Perry, ML; Ribeiro, CA; Rosa, RB; Schuck, PF; Wajner, M; Wannmacher, CM; Wyse, AT1
Baldellou, A; Briones, P; Campistol, J; Cortés, N; Delpiccolo, C; Fernández, C; Fons, C; Fuentes-Castelló, MA; García-Villoria, J; González, I; Hernández-Gonzalez, A; Messeguer, A; Navarro-Sastre, A; Pérez-Cerdá, C; Ribes, A1
Arica, SG; Arica, V; Dag, H; Gülbayzar, S; Obut, O; Onur, H1
Akiba, K; Aoyama, Y; Fukao, T; Goto, M; Hasegawa, Y; Hashimoto, T; Hori, T; Kuwayama, N; Morita, M; Moriyama, Y; Murayama, K; Ohtake, A; Shigematsu, Y; Usuda, N; Venkatesan, R; Wierenga, R1
Bancel, LP; Dessein, AF; Germain, N; Guemann, AS; Joncquel Chevalier Curt, M1

Other Studies

12 other study(ies) available for alpha-methyl-beta-hydroxybutyrate and glycine

ArticleYear
Abnormal metabolites of isoleucine in a patient with propionyl-CoA carboxylase deficiency.
    Biomedical mass spectrometry, 1978, Volume: 5, Issue:3

    Topics: Acetoacetates; Carboxy-Lyases; Child, Preschool; Consanguinity; Female; Glycine; Humans; Hydroxy Acids; Hydroxybutyrates; Isoleucine; Keto Acids; Pentanoic Acids; Propionates

1978
Urinary excretion of 2-methylacetoacetate, 2-methyl-3-hydroxybutyrate and tiglylglycine after isoleucine loading in the diagnosis of 2-methylacetoacetyl-CoA thiolase deficiency.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:1

    Topics: Acetoacetates; Acetyl-CoA C-Acyltransferase; Butanones; Glycine; Humans; Hydroxybutyrates; Infant; Isoleucine; Male

1991
Acetoacetyl CoA thiolase deficiency presenting as ketotic hypoglycemia.
    Pediatric research, 1987, Volume: 21, Issue:2

    Topics: Acetoacetates; Acetyl-CoA C-Acetyltransferase; Acetyltransferases; Acidosis; Female; Glycine; Humans; Hydroxybutyrates; Hypoglycemia; Infant; Ketosis

1987
3-Ketothiolase deficiency.
    European journal of pediatrics, 1986, Volume: 144, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetyl-CoA C-Acyltransferase; Acyl Coenzyme A; Acyltransferases; Child; Female; Fibroblasts; Glycine; Humans; Hydroxybutyrates; Infant; Isoleucine; Ketosis; Male; Valerates

1986
A case of beta-ketothiolase deficiency.
    Journal of inherited metabolic disease, 1983, Volume: 6, Issue:4

    Topics: Acetyl-CoA C-Acyltransferase; Acidosis; Acyltransferases; Dietary Proteins; Female; Glycine; Humans; Hydroxybutyrates; Infant

1983
Late onset type of propionic acidaemia: case report and biochemical studies.
    Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2

    Topics: Acidosis; Amino Acid Metabolism, Inborn Errors; Carbon-Carbon Ligases; Female; Glycine; Humans; Hydroxybutyrates; Infant; Ketosis; Ligases; Propionates

1981
Beta-ketothiolase deficiency in a family confirmed by in vitro enzymatic assays in fibroblasts.
    European journal of pediatrics, 1982, Volume: 139, Issue:1

    Topics: Acetyl-CoA C-Acyltransferase; Acidosis; Acyltransferases; Adult; Child; Fibroblasts; Glycine; Humans; Hydroxybutyrates; Male; Metabolism, Inborn Errors

1982
Inhibition of energy metabolism by 2-methylacetoacetate and 2-methyl-3-hydroxybutyrate in cerebral cortex of developing rats.
    Journal of inherited metabolic disease, 2005, Volume: 28, Issue:4

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetates; Acetoacetates; Acetyl-CoA C-Acyltransferase; Acidosis; Alcohol Oxidoreductases; Animals; Brain; Carbon Dioxide; Cerebral Cortex; Citrates; Creatine Kinase; Dose-Response Relationship, Drug; Electron Transport; Energy Metabolism; Glucose; Glutathione; Glycine; Hydroxybutyrates; In Vitro Techniques; Intellectual Disability; Lactic Acid; NG-Nitroarginine Methyl Ester; Oxygen; Rats; Rats, Wistar; Time Factors

2005
Study of patients and carriers with 2-methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency: difficulties in the diagnosis.
    Clinical biochemistry, 2009, Volume: 42, Issue:1-2

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Alcohol Oxidoreductases; Amino Acid Metabolism, Inborn Errors; Female; Glycine; Heredodegenerative Disorders, Nervous System; Humans; Hydroxybutyrates; Infant; Infant, Newborn; Male; Valerates

2009
Beta-ketothiolase deficiency brought with lethargy: case report.
    Human & experimental toxicology, 2011, Volume: 30, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetyl-CoA C-Acyltransferase; Amino Acid Metabolism, Inborn Errors; Carnitine; Female; Glycine; Humans; Hydroxybutyrates; Infant; Ketosis; Lethargy

2011
The first case in Asia of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (HSD10 disease) with atypical presentation.
    Journal of human genetics, 2014, Volume: 59, Issue:11

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acetyl-CoA C-Acetyltransferase; Base Sequence; Carnitine; Child; Diagnosis, Differential; DNA Mutational Analysis; Dyskinesias; Fibroblasts; Glycine; Humans; Hydroxybutyrates; Immunoblotting; Lipid Metabolism, Inborn Errors; Male; Mental Retardation, X-Linked; Mitochondria; Models, Molecular; Point Mutation; Protein Structure, Tertiary

2014
Abnormal Ketone Bodies in a 22-Month-Old Boy Presenting with Recurrent Vomiting and Metabolic Acidosis.
    Clinical chemistry, 2019, Volume: 65, Issue:11

    Topics: Acetoacetates; Acetyl-CoA C-Acyltransferase; Acidosis; Amino Acid Metabolism, Inborn Errors; Glycine; Humans; Hydroxybutyrates; Infant; Ketone Bodies; Male; Vomiting

2019