alpha-methyl-4-carboxyphenylglycine has been researched along with glycine in 315 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 164 (52.06) | 18.2507 |
| 2000's | 113 (35.87) | 29.6817 |
| 2010's | 38 (12.06) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO | 1 |
| Bear, MF; Lee, HK; Malenka, RC; Selig, DK | 1 |
| Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG | 1 |
| Batchelor, AM; Garthwaite, J; Madge, DJ | 1 |
| Chase, LA; Johansen, PA; Johnson, RL; Koerner, JF; Robinson, MB; Sinor, AD | 1 |
| Arvanov, V; Holmes, K; Keele, NB; Shinnick-Gallagher, P | 1 |
| Haun, SE; Horrocks, LA; Lipscomb, DC; Segeleon, JE; Trapp, VL | 1 |
| Eaton, SA; Salt, TE | 1 |
| Jane, DE; Jones, PL; Pook, PC; Salt, TE; Sunter, DC; Watkins, JC | 1 |
| Fedorov, NB; Reymann, KG; Sergueeva, OA | 1 |
| Arvanov, VL; Holmes, KH; Keele, NB; Shinnick-Gallagher, P | 1 |
| Bordi, F; Ugolini, A | 2 |
| Battaglia, G; Bruno, V; Copani, A; Leanza, G; Nicoletti, F; Pellitteri, R; Russo, A; Stanzani, S | 1 |
| Bashir, ZI; Collingridge, GL | 1 |
| Casabona, G; Reymann, KG; Riedel, G | 1 |
| Haruta, H; Hicks, TP; Kamishita, T; Takahashi, MP; Tsumoto, T | 1 |
| Cavanni, P; Ferraguti, F; Mugnaini, M; Pinnola, V; Trist, D; Van Amsterdam, FT | 1 |
| Bridges, RJ; Chamberlin, AR; Cotman, CW; Miller, S | 1 |
| Gähwiler, BH; Gerber, U; Lüthi, A | 1 |
| Littman, L; Robinson, MB | 1 |
| Opitz, T; Reymann, KG; Richter, P | 1 |
| Manzoni, OJ; Nicoll, RA; Weisskopf, MG | 1 |
| Collingridge, GL; Henley, JM; Irving, AJ; Seal, AJ | 1 |
| Dichter, MA; Maki, R; Robinson, MB | 1 |
| Bliss, TV; Errington, ML; Maegawa, H; Richter-Levin, G | 1 |
| Izumi, Y; Zorumski, CF | 1 |
| Cahusac, PM | 1 |
| Brown, RE; Rabe, H; Reymann, KG | 1 |
| Burke, JP; Hablitz, JJ | 2 |
| Hartell, NA | 1 |
| Hölscher, C | 1 |
| Aniksztejn, L; Ben-Ari, Y; Chinestra, P; Diabira, D | 1 |
| Bendali, N; Knöpfel, T; Lingenhöhl, K; Olpe, HR | 1 |
| Bashir, ZI; Bortolotto, ZA; Collingridge, GL; Davies, CH | 1 |
| Jane, D; Jones, A; Jones, P; Kemp, M; Pook, P; Roberts, P; Sunter, D; Udvarhelyi, P; Watkins, J | 1 |
| Reymann, KG; Riedel, G; Wetzel, W | 1 |
| Birse, EF; Hayashi, Y; Jane, DE; Nakanishi, S; Sekiyama, N; Sunter, DC; Udvarhelyi, PM; Watkins, JC | 1 |
| Bashir, ZI; Collingridge, GL; Jane, DE; Sunter, DC; Watkins, JC | 1 |
| Reymann, K; Riedel, G | 1 |
| Eaton, SA; Jane, DE; Jones, PL; Pook, PC; Porter, RH; Roberts, PJ; Salt, TE; Sunter, DC; Udvarhelyi, PM; Watkins, JC | 1 |
| Bashir, ZI; Berretta, N; Bortolotto, ZA; Collingridge, GL; Davies, CH; Henley, JM; Irving, AJ; Jane, DE; Seal, AJ; Watkins, JC | 1 |
| Burnett, JP; Kingston, AE; Lodge, D; Mayne, NG | 1 |
| Anwyl, R; Rowan, MJ; Wang, Y | 1 |
| Cardoso, LF; Martini, LH; Souza, DO; Tasca, CI; Vendite, D | 1 |
| O'Dell, TJ; Thomas, MJ | 1 |
| Li, A; Nattie, EE | 1 |
| Abeliovich, A; Aiba, A; Castillo, PE; Hsia, AY; Nicoll, RA; Salin, PA; Tonegawa, S | 1 |
| Choi, S; Lovinger, DM | 1 |
| Ohno, M; Watanabe, S | 1 |
| Hensch, TK; Stryker, MP | 1 |
| Delahunty, TM; Gong, QZ; Hamm, RJ; Lyeth, BG | 1 |
| Dalby, NO; Thomsen, C | 1 |
| Kobayashi, K; Manabe, T; Takahashi, T | 1 |
| Berrino, L; D'Amico, M; de Novellis, V; Pizzirusso, A; Rossi, F | 1 |
| Dichter, MA; Fitzsimonds, RM | 1 |
| Beninger, RJ; Smith, ID | 1 |
| Challiss, RA; Mistry, R | 1 |
| Bockaert, J; Manahan-Vaughan, D; Pin, JP; Reiser, M; Reymann, KG; Riedel, G; Wilsch, V | 1 |
| Reymann, KG; Riedel, G; Wagner, T; Wetzel, W | 1 |
| Haruta, H; Hicks, TP; Kamishita, T; Torii, N; Tsumoto, T | 1 |
| Manahan-Vaughan, D; Reymann, KG | 1 |
| D'Angelo, E; rossi, P; Taglietti, V | 1 |
| Consolandi, O; Memo, M; Pizzi, M; Spano, PF | 1 |
| Orlando, LR; Penney, JB; Standaert, DG; Young, AB | 1 |
| Nozaki-Taguchi, N; Yamamoto, T | 1 |
| Faden, AI; Fan, L; Mukhin, A | 1 |
| Ohno-Shosaku, T; Yamamoto, C | 1 |
| Grover, LM; Little, Z; Teyler, TJ | 1 |
| Eaton, SA; Salt, TE; Turner, JP | 1 |
| Liu, YB; Pasternak, JF; Trommer, BL | 1 |
| Opitz, T; Reymann, KG; Riedel, G | 1 |
| McGinty, JF; Wang, JQ | 1 |
| Forni, C; Kerkerian-Le Goff, L; Nieoullon, A; Pisano, P; Samuel, D | 1 |
| Attwell, D; Sarantis, M; Takahashi, M | 1 |
| Glitsch, M; Llano, I; Marty, A | 1 |
| el Manira, A; Grillner, S; Krieger, P | 1 |
| Cummings, DD; Dichter, MA; Maki, R | 1 |
| Bordi, F; Chiamulera, C; Marcon, C; Reggiani, A | 1 |
| Bhardwaj, A; Hanley, DF; Koehler, RC; Martin, LJ; Northington, FJ; Traystman, RJ | 1 |
| King, AE; Liu, XH | 1 |
| Dingledine, R; Doherty, J | 1 |
| Coderre, TJ; Fisher, K | 1 |
| Arai, I; Inoue, H; Shibata, S; Shimazoe, T; Watanabe, S; Yoshimatsu, A | 1 |
| Coderre, TJ; Fundytus, ME; Ritchie, J | 1 |
| McCarthy, KD; Shao, Y | 1 |
| Chiamulera, C; Conquet, F; Corti, C; Ferraguti, F; Pietra, C; Valerio, E | 1 |
| O'Connor, JJ; O'Leary, DM | 1 |
| Colley, PA; Overstreet, LS; Pasternak, JF; Slater, NT; Trommer, BL | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Pisani, A | 1 |
| Deng, A; Growdon, JH; Nitsch, RM; Wurtman, RJ | 1 |
| Attucci, S; Cozzi, A; Luneia, R; Marinozzi, M; Moroni, F; Pellicciari, R; Peruginelli, F | 1 |
| Howard, JA; Jane, DE; Sunter, DC; Watkins, JC; Wilson, C | 1 |
| Komori, Y; Nabeshima, T; Nikai, T; Senzaki, K; Sugihara, H; Yamada, K | 1 |
| Billard, JM; Dutar, P; Jouvenceau, A | 1 |
| Abbott, A; Lacey, MG; Wigmore, MA | 1 |
| Copenhagen, DR; Dixon, DB | 1 |
| Deitmer, JW; Lohr, C | 1 |
| Dumas, TC; Foster, TC | 1 |
| Bear, MF; Huber, KM; Sawtell, NB | 1 |
| Martin, SJ; Morris, RG | 1 |
| Hounsgaard, J; Svirskis, G | 1 |
| de Mendonça, A; Ribeiro, JA | 1 |
| Kim, JH; Vezina, P | 2 |
| Gunasekar, PG; Isom, GE; Kane, MD; Yang, CW | 1 |
| Kennedy, RT; Lada, MW; Vickroy, TW | 1 |
| Beart, PM; Jones, NM; Lawrence, AJ | 1 |
| Amos, BJ; Chesler, M | 1 |
| Anwyl, R; Breakwell, NA; Rowan, MJ | 1 |
| Lacey, MG; Wigmore, MA | 1 |
| Cassidy, EM; O'Connor, JJ; O'Leary, DM | 1 |
| Anwyl, R; Rowan, MJ; Wang, Y; Wu, J | 1 |
| Wang, JQ | 1 |
| Alger, BE; Kirov, SA; Morishita, W | 1 |
| Salt, TE; Turner, JP | 1 |
| Golshani, P; Jones, EG; Warren, RA | 1 |
| McGee, J; Sanes, DH; Walsh, EJ | 1 |
| Balschun, D; Wetzel, W | 1 |
| Balschun, D; Behnisch, T; Jäger, T; Reymann, KG; Wilsch, VW | 1 |
| Anchisi, D; Miniaci, MC; Strata, P; Tempia, F | 1 |
| Grassi, S; Malfagia, C; Pettorossi, VE | 1 |
| Behrens, MM; Canzoniero, LM; Choi, DW; Lobner, D; Strasser, U | 1 |
| Sayer, RJ | 1 |
| Chandler, SH; Del Negro, CA | 1 |
| Carlen, PL; Perez Velazquez, JL; Skinner, FK; Tian, GF; Wu, CP; Zhang, L; Zhang, Y | 1 |
| Bernardi, G; Spadoni, F; Stefani, A | 1 |
| DeLorenzo, RJ; Pal, S; Sombati, S | 1 |
| Manahan-Vaughan, D; Nakic, M; Reymann, KG; Schachner, M | 1 |
| Pezzola, A; Pintor, A; Tiburzi, F; Volpe, MT | 1 |
| Agrawal, SK; Fehlings, MG; Theriault, E | 1 |
| Foley, CM; Hasser, EM; Hay, M; Moffitt, JA | 1 |
| Hyson, RL | 1 |
| Bonagamba, LG; Haibara, AS; Machado, BH | 1 |
| Coogan, AN; O'Connor, JJ; O'Leary, DM | 1 |
| Gee, CE; Lacaille, JC; Robitaille, R; Woodhall, G | 1 |
| Davidoff, RA; Hackman, JC; Holohean, AM | 1 |
| Haas, HL; Yanovsky, Y | 1 |
| Anwyl, R; Huang, L; Rowan, MJ | 1 |
| Bortolotto, ZA; Collingridge, GL | 2 |
| Chapman, AG; Harris, JR; Meldrum, BS; Quinn, LP; Tang, E; Yap, JS; Yip, PK | 1 |
| Masgrau, R; Picatoste, F; Sarri, E; Servitja, JM | 1 |
| Berthele, A; Biber, K; Boddeke, HW; Gebicke-Härter, PJ; Laurie, DJ; Sommer, B; Tölle, TR; van Calker, D | 1 |
| Kato, BM; Rubel, EW | 1 |
| Battaglia, G; Bruno, V; Catania, MV; Di Grezia, R; Kingston, A; Nicoletti, F; O'Neill, MJ | 1 |
| Behnisch, T; Manahan-Vaughan, D; Reymann, KG | 1 |
| Collingridge, GL; Kilpatrick, IC; Palmer, MJ; Schnabel, R | 1 |
| Bongianni, F; Deliagina, TG; Grillner, S | 1 |
| Foley, CM; Hasser, EM; Hay, M; Mueller, PJ; Vogl, HW | 1 |
| Keele, NB; Neugebauer, V; Shinnick-Gallagher, P | 1 |
| Baldani-Guerra, B; Corsi, M; Corti, C; Ferraguti, F; Nakanishi, S | 1 |
| Cardoso, LF; Souza, DO; Tasca, CI | 1 |
| Bashir, ZI; Brown, MW; Tillett, CW; Ziakopoulos, Z | 1 |
| Angenstein, F; Reyman, KG; Riedel, G; Staak, S | 1 |
| Araque, A; Haydon, PG; Sanzgiri, RP | 1 |
| Arcaya, JL; Cano, G; Cuesta, MC; Maixner, W; Sanchez, L; Suarez-Roca, H | 1 |
| Olkowski, JL; Slusher, BS; Thomas, AG; Vornov, JJ | 1 |
| Collingridge, GL; Kilpatrick, IC; Schnabel, R | 1 |
| Hanania, T; Johnson, KM | 1 |
| Mathis, C; Ungerer, A | 1 |
| Auclair, N; Crépel, F; Desce, JM; Otani, S; Roisin, MP | 1 |
| Blanc, EM; Guiramand, J; Jallageas, M; Recasens, M | 1 |
| Cozzi, A; Leonardi, P; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F | 1 |
| Hirouchi, M; Itoh, Y; Kimura, K; Oka, M; Ukai, Y | 1 |
| Battaglia, G; Bond, A; Bruno, V; Clark, BP; Harris, JR; Kingston, AE; Lodge, D; Monn, JA; Nicoletti, F; O'Neill, MJ; Schoepp, DD | 1 |
| Bianchin, MM; Izquierdo, I; McGaugh, JL; Roesler, R; Spanis, CW | 1 |
| Nakamura, K; Shirane, M | 1 |
| Benarese, M; Boroni, F; Goffi, F; Pizzi, M; Spano, PF; Valerio, A | 1 |
| Fuwa, T; Miwa, H; Mizuno, Y; Nishi, K | 1 |
| Kato, K; Li, ST; Mikoshiba, K | 1 |
| Hamba, M; Onodera, K; Takahashi, T | 1 |
| Albani-Torregrossa, S; Cattabeni, F; Colciaghi, F; De Graan, PN; Di Luca, M; Gardoni, F; Moroni, F; Pastorino, L; Pellegrini-Giampietro, DE | 1 |
| Blatow, M; Giuffrida, R; Monyer, H; van Hooft, JA | 1 |
| Ross, ST; Soltesz, I | 1 |
| Croucher, MJ; Harris, JR; Jane, DE; Thomas, LS | 1 |
| Chen, J; Sandkühler, J | 1 |
| Hirai, H; Launey, T | 1 |
| Beeler, JA; Kim, JH; Vezina, P | 1 |
| Barrachina, MD; Esplugues, JV; García-Zaragozá, E; Moreno, L | 1 |
| Changeux, JP; Klink, R; Korn, H; Léna, C; Tsuneki, H | 1 |
| Ben-Ari, Y; Dzhala, VI; Luhmann, HJ | 1 |
| Queen, AL; Vezina, P | 1 |
| Ardenghi, PG; Barros, DM; Izquierdo, I; Izquierdo, LA; Medina, JH; Mello e Souza, T; Pereira, P | 1 |
| Binns, KE; Salt, TE | 1 |
| Chu, Z; Hablitz, JJ | 1 |
| Dempsey, RJ; Hatcher, JF; Rao, AM | 1 |
| Lin, Q; Liu, W; Lu, XM; Slusher, BS; Tang, Z | 1 |
| Bao, W; Faden, AI; Fan, L; Movsesyan, VA; Mullins, PG; O'Leary, DM | 1 |
| Yang, SN | 1 |
| Cano, J; Machado, A; Matarredona, ER; Santiago, M; Venero, JL | 1 |
| Blanc, G; Darracq, L; Drouin, C; Glowinski, J; Tassin, JP | 1 |
| Martin, SJ | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Conquet, F; Gubellini, P; Pisani, A; Saulle, E | 1 |
| Goda, Y; Hagler, DJ | 1 |
| Jiang, L; Kang, J; Nedergaard, M; Xu, J | 1 |
| Asai, K; Fujita, K; Katano, H; Kato, T; Kawamura, Y; Masago, A; Yamada, K | 1 |
| Conn, PJ; Mannaioni, G; Marino, MJ; Traynelis, SF; Valenti, O | 1 |
| Chamberlain, M; Johnson, MP; Kelly, G | 1 |
| Averill, DB; Li, DP; Pan, HL | 1 |
| Bonsi, P; Miniaci, MC; Pisani, A; Strata, P; Tempia, F | 1 |
| Olkowski, JL; Slusher, BS; Thomas, AG | 1 |
| Brasnjo, G; Otis, TS | 1 |
| Bellomo, M; Catania, MV; De Blasi, A; Di Giorgi-Gerevini, V; Giuffrida, R; Nicoletti, F; Romeo, R; Seminara, G | 1 |
| Bernardi, G; Berretta, N; Mercuri, NB; Paolucci, E | 1 |
| Bernardi, G; Bonsi, P; Calabresi, P; Centonze, D; Conquet, F; Gubellini, P; Picconi, B; Pisani, A | 1 |
| Hirose, K; Iino, M; Kakizawa, S; Okubo, Y | 1 |
| Kelland, EE; Toms, NJ | 1 |
| Mao, L; Wang, JQ | 1 |
| Chen, Y; Lu, Y; Westlund, KN; Zhang, L | 1 |
| Merlin, LR | 1 |
| Alcocer, I; Bermúdez-Rattoni, F; Escobar, ML | 1 |
| Ikegaya, Y; Koyama, R; Matsuki, N; Nishiyama, N; Yamada, MK | 1 |
| Hulsebosch, CE; Johnson, KM; Mills, CD | 1 |
| Jingami, H; Kamiya, N; Kunishima, N; Morikawa, K; Tsuchiya, D | 1 |
| Challiss, RA; McIlhinney, RA; Rhodes, A; Selkirk, JV | 1 |
| Cudeiro, J; Martínez, LM; Rivadulla, C; Varela, C | 1 |
| Leung, LS; Ma, J | 1 |
| Eysel, UT; Huemmeke, M; Mittmann, T | 1 |
| Baker, RS; Chamberlain, MJ; Clark, BP; Griffey, K; Harris, JR; Johnson, BG; Johnson, MP; Kelly, G; Kingston, AE; Schoepp, DD; Tizzano, JT; Tomlinson, R; Wright, RA | 1 |
| Bianchi, R; Chuang, SC; Lee, AC; Shin, HS; Wong, RK | 1 |
| Johnson, SW; Zheng, F | 1 |
| Boldyrev, AA; Bulygina, ER; Lyapina, LY | 1 |
| Antunes, VR; Machado, BH | 1 |
| Bernardi, G; Calabresi, P; Centonze, D; Conquet, F; Costa, C; Gubellini, P; Saulle, E; Tropepi, D | 1 |
| Croucher, MJ; Lee, JJ | 1 |
| Chen, G; Dunbar, RL; Ebner, TJ; Gao, W; Oberdick, J; Reinert, KC | 1 |
| Berretta, N; Cherubini, E; Gasparini, S; M Kasyanov, A; Rossokhin, AV; Sokolov, MV; Voronin, LL | 1 |
| Fei, Z; Liu, EY; Zhang, X | 1 |
| Foster, AC; Naeve, GS; Selkirk, JV | 1 |
| Gear, RW; Levine, JD; Tambeli, CH; Young, A | 1 |
| Camaioni, E; Cavanni, P; Costantino, G; Faedo, S; Marinozzi, M; Micheli, F; Moroni, F; Natalini, B; Noe, C; Pellicciari, R; Sarichelou, I | 1 |
| Clinckers, R; Ebinger, G; Lindekens, H; Lodge, D; Meurs, A; Michotte, Y; O'Neill, MJ; Smolders, I | 1 |
| Kelly, E; Mundell, SJ; Pula, G; Roberts, PJ | 1 |
| Karakossian, MH; Otis, TS | 1 |
| Kelly, E; McIlhinney, RA; Mundell, SJ; Pula, G; Roberts, PJ | 1 |
| Becker, A; Grecksch, G; Nagaraja, RY; Reymann, KG; Schroeder, H | 1 |
| Hou, L; Klann, E | 1 |
| Cammalleri, M; Francesconi, W; Sanna, PP | 1 |
| Arvanian, VL; Mendell, LM; Motin, V | 1 |
| Branco, LG; de Paula, PM | 2 |
| Manahan-Vaughan, D; Naie, K | 1 |
| Holtzclaw, L; Hyman, SE; Russell, JT; Voulalas, PJ; Wolstenholme, J | 1 |
| de Novellis, V; Maione, S; Marabese, I; Mariani, L; Palazzo, E; Rossi, F; Scafuro, M; Vita, D | 1 |
| Balschun, D; Becker, A; Nagaraja, RY; Reymann, KG | 1 |
| Baskys, A; Bayazitov, I; Blaabjerg, M; Fang, L; Poulsen, FR; Zimmer, J | 1 |
| Ahn, DK; Bae, YC; Choi, HS; Jung, CY; Kim, KH; Lim, EJ; Youn, DH | 1 |
| Heinke, B; Sandkühler, J | 1 |
| Galik, J; Gerber, G; Park, YK; Randić, M; Voitenko, N; Youn, DH | 1 |
| Andree, TH; Gong, X; Liu, F; Marquis, K; Reinhart, P; Zhang, G | 1 |
| Imanishi, M; Kaneda, K; Kita, H; Nambu, A; Shigemoto, R; Tachibana, Y; Takada, M | 1 |
| Ennis, M; Hayar, A; Heinbockel, T; Zhu, M | 1 |
| Konieczny, J; Kuter, K; Ossowska, K; Pietraszek, M; Pilc, A; Wardas, J; Wolfarth, S | 1 |
| Azzi, M; Kougioumoutzakis, A; Lacaille, JC; Morin, F; Topolnik, L | 1 |
| Chiocchetti, A; Dianzani, C; Dianzani, U; Fantozzi, R; Lombardi, G; Mesturini, R; Miglio, G; Mocellin, M; Orilieri, E; Varsaldi, F | 1 |
| Blethyn, KL; Cope, DW; Crunelli, V; Hughes, SW; Tsomaia, V; Zhu, L | 1 |
| Antion, MD; Hou, L; Hu, D; Klann, E; Paylor, R; Spencer, CM | 1 |
| Ahn, DK; Bae, YC; Choi, HS; Ju, JS; Kim, SK; Lee, HJ; Yoon, YW | 1 |
| Batchelor, AM; Fukunaga, I; Yeo, CH | 1 |
| Castro, JB; Hovis, KR; Urban, NN | 1 |
| Coulibaly, AP; Dopheide, MM; Schachtman, TR; Serfozo, P; Shelat, PB; Simonyi, A | 1 |
| Croucher, MJ; Datla, KP; Dexter, DT; Vernon, AC; Zbarsky, V | 1 |
| Boulware, MI; Christensen, A; Dewing, P; Mermelstein, PG; Micevych, P; Sinchak, K | 1 |
| Dobrunz, LE; Speed, HE | 1 |
| Lacaille, JC; Le Vasseur, M; Ran, I | 1 |
| Anwyl, R; Hayes, J; Li, S; Rowan, MJ | 1 |
| Murotomi, K; Ono, M; Takagi, N; Takayanagi, G; Takeo, S; Tanonaka, K | 1 |
| Chergui, K; Schotanus, SM | 1 |
| Jiang, ZZ; Liu, Y; Shang, J; Wang, S; Wang, W; Zhang, LY; Zhang, Z | 1 |
| Faria, LC; Fuortes, MG; Merlin, LR | 1 |
| Aiba, A; Kashiwadani, H; Matsumoto, H; Mori, K; Nagao, H | 1 |
| Chen, G; Ebner, T; Gao, W; Wang, X | 1 |
| Araneda, RC; Smith, RS; Weitz, CJ | 1 |
| Deng, PY; Lei, S; Xiao, Z | 1 |
| Hariri, OR; Kuo, J; Micevych, P | 1 |
| Bondar, G; Hamid, N; Kuo, J; Micevych, P | 1 |
| Aas, P; Enger, S; Myhrer, T | 1 |
| Feng, DD; Han, JZ; Li, C; Li, JF; Liu, HJ; Liu, XY; Liu, Y; Luo, ZQ; Shen, L; Xu, JP; Yue, SJ | 1 |
| Honda, TA; Mizutani, R; Murotomi, K; Ono, M; Takagi, N; Takeo, S; Tanonaka, K | 1 |
| Hewett, JA; Hewett, SJ; Jackman, NA; Uliasz, TF | 1 |
| Kim, SY; Park, ES; Youn, DH | 1 |
| Américo, TA; Arantes, CP; Beraldo, FH; Caetano, FA; Ferguson, SS; Hajj, GN; Lee, KS; Linden, R; Lopes, MH; Machado, CF; Magalhães, AC; Magdesian, MH; Mancini, GL; Martins, VR; Prado, MA; Roffe, M; Santos, TG | 1 |
| Araque, A; Navarrete, M | 1 |
| Ji, G; Li, Z; Neugebauer, V | 1 |
| Booth, CA; Brown, JT; Randall, AD | 1 |
| Chen, G; Ebner, TJ; Gao, W; Wang, X | 1 |
| Iwagaki, N; Miles, GB | 1 |
| Kullmann, DM; Le Duigou, C | 1 |
| Bernardinelli, Y; Farmer, WT; Jones, EV; Murai, KK; Salmon, C; Stellwagen, D | 1 |
| Moreira, TS; Takakura, AC | 1 |
| Ji, G; Neugebauer, V | 1 |
| Burger, C; Gerstein, H; O'Riordan, K; Osting, S; Schwarz, M | 1 |
| Addae, JI; Darlington, LG; Forrest, CM; Morris, BJ; Murthy, S; Stone, TW | 1 |
| Gieros, K; Salinska, E; Sobczuk, A | 1 |
| Fischer, L; Menescal-de-Oliveira, L; Monaliza, SL; Parada, CA; Tambeli, CH | 1 |
| Chen, L; Chen, WF; Sun, XR; Yung, WH | 1 |
| Bahmanpour, S; Namavar, R; Nikbakht, F; Rastegar, K; Yeganeh, F | 1 |
| Dong, Y; Grace, AA; Huang, YH; Ishikawa, M; Neumann, PA; Otaka, M; Schlüter, OM; Winters, BD | 1 |
| Ding, S; Li, H; Sun, G; Zhang, N | 1 |
| Cao, J; Duan, TT; Jing, L; Xu, L; Yuan, Q; Zhou, QX; Zhu, YY | 1 |
| Boulware, MI; Frick, KM; Heisler, JD | 1 |
| Brown, EM; Conn, PJ; Hall, RA; Hamelberg, D; Jiang, JY; Meyer, RC; Nagaraju, M; Yang, JJ; Zhang, L | 1 |
| Copeland, CS; Jones, HE; Salt, TE; Sillito, AM | 1 |
| Scheyer, AF; Tseng, KY; Wolf, ME | 1 |
| Lee, HA; Li, DP; Pachuau, J; Pan, HL; Zhu, LH | 1 |
| Morton, RA; Valenzuela, CF; Zamudio-Bulcock, PA | 1 |
| Hao, L; Xie, F; Yi, SL; Zhang, Y; Zhong, JQ | 1 |
| Chou, D; Hsu, KS; Huang, CC; Yeh, CM | 1 |
| Eom, HS; Jo, SK; Jung, U; Kim, SH; Kim, YS; Moon, C; Park, HR | 1 |
| Corcia, M; Friedman, LK; Hong, H; Hu, S; Kantrowitz, M; Khalil, Y; Qazi, L; Sharma, A; Simsovits, D; Webster, T | 1 |
| Edwards, RH; Nicoll, RA; Sheng, N; Silm, K; Yang, J | 1 |
| Blazquez-Llorca, L; Freitag, SV; Herms, J; Ovsepian, SV; Rodrigues, EF | 1 |
| Caccamise, A; Chauhan, NM; Loweth, JA; Reimers, JM; Stefanik, MT; Werner, CT; Wolf, ME; Woo, KKY | 1 |
2 review(s) available for alpha-methyl-4-carboxyphenylglycine and glycine
| Article | Year |
|---|---|
Ligands for glutamate receptors: design and therapeutic prospects.
Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses | 2000 |
An influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats.
Topics: Animals; Benzoates; Catalepsy; Corpus Striatum; Enkephalins; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Haloperidol; Humans; Ligands; Parkinson Disease; Protein Precursors; Rats; Receptors, Metabotropic Glutamate; RNA, Messenger | 2007 |
313 other study(ies) available for alpha-methyl-4-carboxyphenylglycine and glycine
| Article | Year |
|---|---|
Reexamination of the effects of MCPG on hippocampal LTP, LTD, and depotentiation.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Long-Term Potentiation; Membrane Potentials; Neuronal Plasticity; Rats; Time Factors | 1995 |
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction | 1994 |
Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cerebellum; Electric Stimulation; Glycine; In Vitro Techniques; Nerve Fibers; Neural Pathways; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synapses | 1994 |
Type 4a metabotropic glutamate receptor: identification of new potent agonists and differentiation from the L-(+)-2-amino-4-phosphonobutanoic acid-sensitive receptor in the lateral perforant pathway in rats.
Topics: Aminobutyrates; Animals; Benzoates; Cell Line; Cricetinae; Cyclic AMP; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Recombinant Proteins; Synaptic Transmission | 1995 |
Agonist action of (RS)-alpha-methyl-4-carboxyphenylglycine (MCPG) in the amygdala.
Topics: Amygdala; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission; Tetrodotoxin | 1995 |
Astroglial phosphoinositide hydrolysis during combined glucose-oxygen deprivation: role of the metabotropic glutamate receptor.
Topics: Alanine; Animals; Animals, Newborn; Astrocytes; Benzoates; Cells, Cultured; Glucose; Glutamic Acid; Glycine; Hydrolysis; Inositol Phosphates; L-Lactate Dehydrogenase; Lithium Chloride; Oxygen; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tritium | 1995 |
The function of metabotropic excitatory amino acid receptors in synaptic transmission in the thalamus: studies with novel phenylglycine antagonists.
Topics: Action Potentials; Air; Animals; Benzoates; Cycloleucine; Glycine; Hot Temperature; Iontophoresis; Neurons; Nociceptors; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thalamus | 1994 |
Stereospecific antagonism by (+)-alpha-methyl-4-carboxyphenylglycine (MCPG) of (1S,3R)-ACPD-induced effects in neonatal rat motoneurones and rat thalamic neurones.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Ibotenic Acid; Motor Neurons; N-Methylaspartate; Neuromuscular Depolarizing Agents; Neurons; Neurotoxins; Rats; Spinal Cord; Stereoisomerism; Thalamus | 1993 |
An antagonist of glutamate metabotropic receptors, (RS)-alpha-methyl-4-carboxyphenylglycine, prevents the LTP-related increase in postsynaptic AMPA sensitivity in hippocampal slices.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Iontophoresis; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate | 1993 |
The functional role of metabotropic glutamate receptors in epileptiform activity induced by 4-aminopyridine in the rat amygdala slice.
Topics: 4-Aminopyridine; Amygdala; Animals; Benzoates; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
Antagonists of the metabotropic glutamate receptor do not prevent induction of long-term potentiation in the dentate gyrus of rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Long-Term Potentiation; Male; Neural Pathways; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
Activation of metabotropic glutamate receptors protects cultured neurons against apoptosis induced by beta-amyloid peptide.
Topics: Aminobutyrates; Amyloid beta-Peptides; Animals; Apoptosis; Benzoates; Calcium Channels; Cells, Cultured; Cerebellum; Cycloleucine; Glycine; Mice; Nerve Degeneration; Neurons; Peptide Fragments; Phosphoserine; Receptors, Metabotropic Glutamate | 1995 |
An investigation of depotentiation of long-term potentiation in the CA1 region of the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine; Benzoates; Electric Stimulation; Female; Glycine; Hippocampus; Long-Term Potentiation; Nimodipine; Nitroarginine; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Time Factors | 1994 |
Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Cyclic AMP; Glycine; Hippocampus; Hydrolysis; Long-Term Potentiation; Male; Motor Activity; Pharmaceutical Vehicles; Phosphatidylinositols; Rats; Rats, Wistar; Reaction Time; Receptors, Metabotropic Glutamate; Stereoisomerism; Synaptic Transmission | 1995 |
Induction of LTD but not LTP through metabotropic glutamate receptors in visual cortex.
Topics: Animals; Benzoates; Calcium; Cycloleucine; Depression, Chemical; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Neurotoxins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Visual Cortex | 1994 |
Pharmacological analysis of carboxyphenylglycines at metabotropic glutamate receptors.
Topics: Adenylyl Cyclases; Animals; Benzoates; CHO Cells; Colforsin; Computer Simulation; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Glycine; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1994 |
Pharmacological dissociation of glutamatergic metabotropic signal transduction pathways in cortical astrocytes.
Topics: Animals; Astrocytes; Benzoates; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Cycloleucine; Dicarboxylic Acids; Glutamic Acid; Glycine; Isoproterenol; Neuroglia; Neurotoxins; Phosphatidylinositols; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1994 |
Inhibition of a slow synaptic response by a metabotropic glutamate receptor antagonist in hippocampal CA3 pyramidal cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Cycloleucine; Evoked Potentials; Glycine; Hippocampus; In Vitro Techniques; Nerve Fibers; Neurotoxins; Pyramidal Cells; Quinoxalines; Rats; Receptors, Glutamate; Synapses | 1993 |
The effects of L-glutamate and trans-(+-)-1-amino-1,3-cyclopentanedicarboxylate on phosphoinositide hydrolysis can be pharmacologically differentiated.
Topics: Alanine; Animals; Animals, Newborn; Aspartic Acid; Benzoates; Brain; Cerebellum; Cycloleucine; Glutamic Acid; Glycine; Hippocampus; Hydrolysis; Ibotenic Acid; Inositol Phosphates; Kinetics; Neurotoxins; Phosphatidylinositols; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
The metabotropic glutamate receptor antagonist (+)-alpha-methyl-4-carboxyphenylglycine protects hippocampal CA1 neurons of the rat from in vitro hypoxia/hypoglycemia.
Topics: Animals; Benzoates; Glucose; Glycine; Hippocampus; Hypoglycemia; Hypoxia; In Vitro Techniques; Neurons; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Stereoisomerism | 1994 |
MCPG antagonizes metabotropic glutamate receptors but not long-term potentiation in the hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Neurotoxins; Receptors, Metabotropic Glutamate; Stereoisomerism; Synapses; Synaptic Transmission | 1994 |
Stereoselective antagonism of the metabotropic glutamate receptor mGluR1 alpha by alpha-methyl-4-carboxyphenylglycine.
Topics: Animals; Benzoates; Calcium; CHO Cells; Cricetinae; Cycloleucine; Glycine; Perfusion; Receptors, Metabotropic Glutamate; Stereoisomerism | 1994 |
The glutamate uptake inhibitor L-trans-pyrrolidine-2,4-dicarboxylate depresses excitatory synaptic transmission via a presynaptic mechanism in cultured hippocampal neurons.
Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Presynaptic Terminals; Pyrrolidines; Rats; Receptors, Amino Acid; Receptors, N-Methyl-D-Aspartate; Stereoisomerism; Synaptic Transmission | 1994 |
Activation of metabotropic glutamate receptors is necessary for long-term potentiation in the dentate gyrus and for spatial learning.
Topics: Animals; Benzoates; Electric Stimulation; Evoked Potentials, Somatosensory; Glycine; Hippocampus; Injections; Injections, Intraventricular; Long-Term Potentiation; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Space Perception | 1994 |
Developmental changes in the effects of metabotropic glutamate receptor antagonists on CA1 long-term potentiation in rat hippocampal slices.
Topics: Aging; Alanine; Aminobutyrates; Animals; Benzoates; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Pyramidal Cells; Rats; Receptors, Metabotropic Glutamate | 1994 |
Cortical layer-specific effects of the metabotropic glutamate receptor agonist 1S,3R-ACPD in rat primary somatosensory cortex in vivo.
Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Glycine; Iontophoresis; Male; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Somatosensory Cortex; Synapses | 1994 |
(RS)-alpha-methyl-4-carboxyphenylglycine (MCPG) does not block theta burst-induced long-term potentiation in area CA1 of rat hippocampal slices.
Topics: Animals; Benzoates; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Theta Rhythm | 1994 |
Presynaptic depression of synaptic transmission mediated by activation of metabotropic glutamate receptors in rat neocortex.
Topics: Aminobutyrates; Animals; Benzoates; Cycloleucine; Electrophysiology; Female; Frontal Lobe; Glycine; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Presynaptic; Synaptic Transmission | 1994 |
Induction of cerebellar long-term depression requires activation of glutamate metabotropic receptors.
Topics: Aniline Compounds; Animals; Benzoates; Biotransformation; Cerebellum; Cyclic GMP; Cycloleucine; Cyclopropanes; Evoked Potentials; Fluorescent Dyes; Glycine; In Vitro Techniques; Nerve Fibers; Neuronal Plasticity; Neurotoxins; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Xanthenes | 1994 |
Inhibitors of metabotropic glutamate receptors produce amnestic effects in chicks.
Topics: Aminobutyrates; Amnesia; Animals; Avoidance Learning; Benzoates; Chickens; Cycloleucine; Cyclopropanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Male; Motor Activity; Phosphoserine; Receptors, Metabotropic Glutamate | 1994 |
(RS)-alpha-methyl-4-carboxyphenylglycine neither prevents induction of LTP nor antagonizes metabotropic glutamate receptors in CA1 hippocampal neurons.
Topics: Animals; Benzoates; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Long-Term Potentiation; Male; Membrane Potentials; Neurons; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Glutamate; Synaptic Transmission | 1993 |
Phenylglycine derivatives antagonize the excitatory response to Purkinje cells to 1S,3R-ACPD: an in vivo and in vitro study.
Topics: Action Potentials; Animals; Benzoates; Cerebellum; Cycloleucine; Electrophysiology; Glycine; In Vitro Techniques; Iontophoresis; Male; Neurotoxins; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1993 |
A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation.
Topics: Animals; Benzoates; Carbazoles; Cycloleucine; Glycine; Hippocampus; In Vitro Techniques; Indole Alkaloids; Long-Term Potentiation; Protein Kinase Inhibitors; Protein Kinases; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1994 |
Antagonism of presynaptically mediated depressant responses and cyclic AMP-coupled metabotropic glutamate receptors.
Topics: Aminobutyrates; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Colforsin; Cyclic AMP; Cycloleucine; Electrophysiology; Glycine; Guinea Pigs; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1994 |
(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) blocks spatial learning in rats and long-term potentiation in the dentate gyrus in vivo.
Topics: Animals; Benzoates; Electroshock; Foot; Glycine; Hippocampus; Injections, Intraventricular; Learning; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reinforcement, Psychology; Retention, Psychology; Spatial Behavior | 1994 |
Analysis of agonist and antagonist activities of phenylglycine derivatives for different cloned metabotropic glutamate receptor subtypes.
Topics: Animals; Benzoates; CHO Cells; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Glycine; Receptors, Metabotropic Glutamate | 1994 |
Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus.
Topics: Animals; Benzoates; Electric Stimulation; Glycine; Hippocampus; In Vitro Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1993 |
An antagonist of the metabotropic glutamate receptor prevents LTP in the dentate gyrus of freely moving rats.
Topics: Animals; Benzoates; Electric Stimulation; Glycine; Hippocampus; Injections, Intraventricular; Long-Term Potentiation; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses | 1993 |
Competitive antagonism at metabotropic glutamate receptors by (S)-4-carboxyphenylglycine and (RS)-alpha-methyl-4-carboxyphenylglycine.
Topics: Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Motor Neurons; N-Methylaspartate; Phosphatidylinositols; Rats; Spinal Cord; Synapses; Thalamus | 1993 |
Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors.
Topics: Action Potentials; Alanine; Animals; Benzoates; CHO Cells; Cricetinae; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1993 |
Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes.
Topics: Animals; Benzoates; Calcium; Cells, Cultured; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrolysis; Phosphatidylinositols; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1995 |
(RS)-alpha-Methyl-4-carboxyphenylglycine inhibits long-term potentiation only following the application of low frequency stimulation in the rat dentate gyrus in vitro.
Topics: Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Rats | 1995 |
Modulation of adenosine-induced cAMP accumulation via metabotropic glutamate receptors in chick optic tectum.
Topics: Adenosine; Alanine; Animals; Benzoates; Chickens; Cyclic AMP; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Male; Quinoxalines; Receptors, Metabotropic Glutamate; Superior Colliculi | 1995 |
The molecular switch hypothesis fails to explain the inconsistent effects of the metabotropic glutamate receptor antagonist MCPG on long-term potentiation.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Receptors, Metabotropic Glutamate; Time Factors | 1995 |
Prolonged stimulation of respiration by brain stem metabotropic glutamate receptors.
Topics: Analysis of Variance; Animals; Benzoates; Brain Stem; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Microinjections; Microscopy, Fluorescence; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Respiration; Stimulation, Chemical | 1995 |
Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Knockout; Protein Kinase C; Receptors, Metabotropic Glutamate | 1995 |
Metabotropic glutamate receptor modulation of voltage-gated Ca2+ channels involves multiple receptor subtypes in cortical neurons.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex; Cycloleucine; Cyclopropanes; Electrophysiology; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Ion Channel Gating; Neurons; Neurotoxins; Nifedipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spider Venoms | 1996 |
Persistent increase in dopamine release following activation of metabotropic glutamate receptors in the rat nucleus accumbens.
Topics: Animals; Benzoates; Chromatography, High Pressure Liquid; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Microdialysis; N-Methylaspartate; Neurotoxins; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1995 |
Ocular dominance plasticity under metabotropic glutamate receptor blockade.
Topics: Animals; Benzoates; Cats; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Photic Stimulation; Receptors, Metabotropic Glutamate; Sensory Deprivation; Vision, Monocular; Visual Cortex; Visual Pathways | 1996 |
Metabotropic glutamate antagonist, MCPG, treatment of traumatic brain injury in rats.
Topics: Analysis of Variance; Animals; Benzoates; Blood Pressure; Brain Injuries; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Glycine; Heart Rate; Infusions, Parenteral; Male; Maze Learning; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
Modulation of seizure activity in mice by metabotropic glutamate receptor ligands.
Topics: Animals; Anticonvulsants; Benzoates; Glycine; Male; Mice; Mice, Inbred DBA; Receptors, Metabotropic Glutamate; Seizures | 1996 |
Presynaptic long-term depression at the hippocampal mossy fiber-CA3 synapse.
Topics: 2-Amino-5-phosphonovalerate; Animals; Axons; Benzoates; Calcium Channel Blockers; Calcium Channels; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred ICR; Neuronal Plasticity; Nicardipine; Pyramidal Cells; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission | 1996 |
Opposing effects on blood pressure following the activation of metabotropic and ionotropic glutamate receptors in raphe obscurus in the anaesthetized rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzoates; Blood Pressure; Cycloleucine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hypertension; Male; Microinjections; N-Methylaspartate; Neurotoxins; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Structure-Activity Relationship; Valine | 1996 |
Heterologous modulation of inhibitory synaptic transmission by metabotropic glutamate receptors in cultured hippocampal neurons.
Topics: Animals; Benzoates; Cells, Cultured; Cycloleucine; Dicarboxylic Acids; Evoked Potentials; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotransmitter Uptake Inhibitors; Patch-Clamp Techniques; Pyrrolidines; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1996 |
Contralateral turning caused by metabotropic glutamate receptor stimulation in the dorsal striatum is reversed by MCPG, TTX, and cis-flupenthixol.
Topics: Animals; Benzoates; Corpus Striatum; Cycloleucine; Dominance, Cerebral; Dopamine Antagonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Flupenthixol; Glycine; Male; Motor Activity; Neurons; Neurotoxins; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereotyped Behavior; Synaptic Transmission; Tetrodotoxin | 1996 |
Differences in agonist and antagonist activities for two indices of metabotropic glutamate receptor-stimulated phosphoinositide turnover.
Topics: Animals; Benzoates; Cerebral Cortex; Cycloleucine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glycine; Inositol 1,4,5-Trisphosphate; Male; Molecular Conformation; Phosphatidylinositols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism | 1996 |
Physiological and pharmacological profile of trans-azetidine-2,4-dicarboxylic acid: metabotropic glutamate receptor agonism and effects on long-term potentiation.
Topics: Animals; Azetidinecarboxylic Acid; Benzoates; Cells, Cultured; Colforsin; Cyclic AMP; Epithelial Cells; Epithelium; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hydrolysis; Inositol Phosphates; Kidney; Long-Term Potentiation; Male; N-Methylaspartate; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Swine; Temperature; Transfection | 1996 |
Open field behaviour in rats: role of metabotropic glutamate receptors.
Topics: Animals; Azetidinecarboxylic Acid; Behavior, Animal; Benzoates; Cyclic AMP; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Space Perception; Type C Phospholipases | 1995 |
Metabotropic glutamate receptors and visual cortical synaptic plasticity.
Topics: Animals; Benzoates; Calcium; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Visual Cortex | 1995 |
Metabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Rats, Wistar; Receptors, Glutamate; Synaptic Transmission | 1995 |
1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo.
Topics: Action Potentials; Animals; Benzoates; Cycloleucine; Dentate Gyrus; Dose-Response Relationship, Drug; Glycine; Long-Term Potentiation; Male; Rats; Rats, Wistar; Synaptic Transmission | 1995 |
Differential long-lasting potentiation of the NMDA and non-NMDA synaptic currents induced by metabotropic and NMDA receptor coactivation in cerebellar granule cells.
Topics: Animals; Benzoates; Cerebellum; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1996 |
Activation of multiple metabotropic glutamate receptor subtypes prevents NMDA-induced excitotoxicity in rat hippocampal slices.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Male; N-Methylaspartate; Neuroprotective Agents; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1996 |
Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions.
Topics: Animals; Benzoates; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1995 |
Zinc protoporphyrin IX, an inhibitor of the enzyme that produces carbon monoxide, blocks spinal nociceptive transmission evoked by formalin injection in the rat.
Topics: Alanine; Animals; Behavior, Animal; Benzoates; Carbon Monoxide; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Heme Oxygenase (Decyclizing); Hot Temperature; Injections, Spinal; Male; Nociceptors; Protoporphyrins; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord; Synaptic Transmission | 1995 |
Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury.
Topics: Animals; Benzoates; Cell Death; Coculture Techniques; Excitatory Amino Acid Antagonists; Glycine; Immunoblotting; Nerve Tissue; Neuroglia; Neurons; Neuroprotective Agents; Oligonucleotides, Antisense; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Effects of metabotropic glutamate receptor agonists on excitatory and inhibitory transmissions in cultured rat hippocampal neurons.
Topics: Animals; Animals, Newborn; Benzoates; Cells, Cultured; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neural Inhibition; Neurons; Neurotoxins; Rats; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Metabotropic glutamate receptor antagonist, (R,S)-alpha-methyl-4-carboxyphenyglycine, blocks two distinct forms of long-term potentiation in area CA1 of rat hippocampus.
Topics: Animals; Benzoates; Calcium Channels; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Ion Channel Gating; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate | 1995 |
Characterization of the metabotropic glutamate receptors (mGluRs) which modulate GABA-mediated inhibition in the ventrobasal thalamus.
Topics: Action Potentials; Alanine; Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glycine; Neurons, Afferent; Physical Stimulation; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Thalamic Nuclei | 1996 |
Long-term depression at the medial perforant path-granule cell synapse in developing rat dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium Channel Blockers; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Male; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1996 |
G-protein activation by metabotropic glutamate receptors reduces spike frequency adaptation in neocortical neurons.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adult; Alanine; Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Enzyme Inhibitors; Frontal Lobe; Glycine; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Isoquinolines; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Protein Kinase Inhibitors; Protein Kinases; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Staurosporine; Sulfonamides; Thionucleotides | 1996 |
Blockade of metabotropic glutamate receptors protects hippocampal neurons from hypoxia-induced cell death in rat in vivo.
Topics: Animals; Behavior, Animal; Benzoates; Cell Death; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Hypoxia, Brain; Injections, Intraventricular; Male; Pilot Projects; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1996 |
Intrastriatal injection of the metabotropic glutamate receptor antagonist MCPG attenuates acute amphetamine-stimulated neuropeptide mRNA expression in rat striatum.
Topics: Amphetamine; Animals; Benzoates; Corpus Striatum; Excitatory Amino Acid Antagonists; Glycine; Male; Neuropeptides; Rats; Rats, Wistar; RNA, Messenger | 1996 |
Involvement of the glutamatergic metabotropic receptors in the regulation of glutamate uptake and extracellular excitatory amino acid levels in the striatum of chloral hydrate-anesthetized rats.
Topics: Amino Acids, Dicarboxylic; Anesthetics, Intravenous; Animals; Benzoates; Chloral Hydrate; Corpus Striatum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Female; Glutamic Acid; Glycine; Potassium; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1996 |
Postsynaptic glutamate uptake in rat cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Aspartic Acid; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Ion Channel Gating; Kynurenic Acid; Membrane Potentials; Monosaccharide Transport Proteins; Neuroprotective Agents; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin | 1996 |
Glutamate as a candidate retrograde messenger at interneurone-Purkinje cell synapses of rat cerebellum.
Topics: 2-Amino-5-phosphonovalerate; Alanine; Animals; Benzoates; Colforsin; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Interneurons; Kinetics; Presynaptic Terminals; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Synaptic Transmission; Tetrodotoxin | 1996 |
Activation of pharmacologically distinct metabotropic glutamate receptors depresses reticulospinal-evoked monosynaptic EPSPs in the lamprey spinal cord.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Axons; Benzoates; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Lampreys; Neural Pathways; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Reticular Formation; Spinal Cord; Synaptic Transmission | 1996 |
Frequency-dependent depression of excitatory synaptic transmission is independent of activation of MCPG-sensitive presynaptic metabotropic glutamate receptors in cultured hippocampal neurons.
Topics: Animals; Benzoates; Cells, Cultured; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Neurons; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1995 |
Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning.
Topics: Animals; Benzoates; Conditioning, Psychological; Cues; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fear; Glycine; Injections, Intraventricular; Male; Maze Learning; Rats; Receptors, Metabotropic Glutamate; Space Perception | 1996 |
Characterization of metabotropic glutamate receptor-mediated nitric oxide production in vivo.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Biomarkers; Calcium Channels; Citrulline; Cycloleucine; Dantrolene; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Microdialysis; Muscle Proteins; N-Methylaspartate; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Ryanodine Receptor Calcium Release Channel; Tetrodotoxin | 1997 |
Dual action of metabotropic glutamate receptor agonists on neuronal excitability and synaptic transmission in spinal ventral horn neurons in vitro.
Topics: Amino Acids, Dicarboxylic; Animals; Anterior Horn Cells; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Rats; Spinal Cord; Synaptic Transmission; Time Factors | 1996 |
Regulation of excitatory input to inhibitory interneurons of the dentate gyrus during hypoxia.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electrophysiology; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hypoxia, Brain; In Vitro Techniques; Interneurons; Kinetics; Male; Membrane Potentials; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, Purinergic P1; Synaptic Transmission | 1997 |
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception.
Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1996 |
Methamphetamine-induced sensitization of dopamine release via a metabotropic glutamate receptor mediated pathway in rat striatal slices.
Topics: Analysis of Variance; Animals; Benzoates; Corpus Striatum; Cycloleucine; Dopamine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraperitoneal; Male; Methamphetamine; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereoisomerism | 1997 |
Attenuation of morphine withdrawal symptoms by subtype-selective metabotropic glutamate receptor antagonists.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Morphine Dependence; Rats; Receptors, Metabotropic Glutamate | 1997 |
Responses of Bergmann glia and granule neurons in situ to N-methyl-D-aspartate, norepinephrine, and high potassium.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Animals; Benzoates; Calcium; Cerebellum; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fluorescent Dyes; Glycine; N-Methylaspartate; Neuroglia; Neurons; Norepinephrine; Organic Chemicals; Potassium; Rats; Rats, Sprague-Dawley; Tetrodotoxin | 1997 |
Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity.
Topics: Analysis of Variance; Animals; Benzoates; Biomarkers; Brain; Cerebral Infarction; Cerebral Ventricles; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; GTP-Binding Proteins; Injections, Intraventricular; Ischemic Attack, Transient; Kainic Acid; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Neurons; Neurotoxins; Receptors, Metabotropic Glutamate; Type C Phospholipases | 1997 |
Potentiation of synaptic transmission in the rat dentate gyrus in vitro by (S)-3,5-dihydroxyphenylglycine ((S)-DHPG).
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Rats; Resorcinols; Stimulation, Chemical; Synaptic Transmission | 1997 |
Metabotropic glutamate receptor mediated long-term depression in developing hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Depression, Chemical; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neuronal Plasticity; Neuroprotective Agents; Nitrendipine; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission; Theophylline | 1997 |
Activation of group III metabotropic glutamate receptors depresses glutamatergic transmission at corticostriatal synapse.
Topics: Aminobutyrates; Animals; Benzoates; Corpus Striatum; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Neural Inhibition; Neuroprotective Agents; Phosphoserine; Presynaptic Terminals; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1997 |
Metabotropic glutamate receptor subtype mGluR1alpha stimulates the secretion of the amyloid beta-protein precursor ectodomain.
Topics: Amyloid beta-Protein Precursor; Benzoates; Cell Line; Cycloleucine; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; GTP-Binding Proteins; Humans; Melitten; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Protein Kinases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Type C Phospholipases | 1997 |
Type 2 metabotropic glutamate (mGlu) receptors tonically inhibit transmitter release in rat caudate nucleus: in vivo studies with (2S,1'S,2'S,3'R)-2-(2'-carboxy-3'-phenylcyclopropyl)glycine, a new potent and selective antagonist.
Topics: Animals; Benzoates; Caudate Nucleus; Corpus Striatum; Cyclic AMP; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neurotransmitter Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1997 |
Absolute configuration of (+)-alpha-methyl-4-carboxyphenylglycine (MCPG), a metabotropic glutamate receptor antagonist.
Topics: Benzoates; Crystallization; Excitatory Amino Acid Antagonists; Glycine; X-Ray Diffraction | 1997 |
Changes in extracellular nitrite and nitrate levels after inhibition of glial metabolism with fluorocitrate.
Topics: Aconitate Hydratase; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Behavior, Animal; Benzoates; Cerebellum; Citrates; Citric Acid Cycle; Cycloleucine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; Male; N-Methylaspartate; Neuroglia; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Nitroarginine; Quinoxalines; Rats; Rats, Wistar; Substrate Specificity | 1997 |
Is activation of the metabotropic glutamate receptors impaired in the hippocampal CA1 area of the aged rat?
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses | 1997 |
Excitation of rat subthalamic nucleus neurones in vitro by activation of a group I metabotropic glutamate receptor.
Topics: Adenine Nucleotides; Affinity Labels; Animals; Benzoates; Cycloleucine; Cyclopropanes; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Male; Neurons; Neuroprotective Agents; Pyridoxal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Thalamic Nuclei | 1997 |
Metabotropic glutamate receptor-mediated suppression of an inward rectifier current is linked via a cGMP cascade.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Aminobutyrates; Animals; Atrial Natriuretic Factor; Benzoates; Cyclic GMP; Enzyme Inhibitors; Glutamic Acid; Glycine; Ictaluridae; Ion Channel Gating; Isoquinolines; Models, Neurological; Patch-Clamp Techniques; Photoreceptor Cells; Potassium Channels; Receptors, Metabotropic Glutamate; Second Messenger Systems; Thionucleotides | 1997 |
Intracellular Ca2+ release mediated by metabotropic glutamate receptor activation in the leech giant glial cell.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Calcium-Transporting ATPases; Central Nervous System; Enzyme Inhibitors; Glutamic Acid; Glycine; Indoles; Intracellular Fluid; Ion Transport; Leeches; Ligands; Membrane Potentials; Neuroglia; Quisqualic Acid; Receptors, Metabotropic Glutamate | 1997 |
Development of metabotropic glutamate receptor-mediated synaptic inhibition.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1997 |
Effects of the metabotropic glutamate receptor antagonist MCPG on phosphoinositide turnover and synaptic plasticity in visual cortex.
Topics: Action Potentials; Age Factors; Animals; Benzoates; Binding, Competitive; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Long-Term Potentiation; Neuronal Plasticity; Neuroprotective Agents; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Metabotropic Glutamate; Synapses; Visual Cortex | 1998 |
(R,S)-alpha-methyl-4-carboxyphenylglycine (MCPG) fails to block long-term potentiation under urethane anaesthesia in vivo.
Topics: Analysis of Variance; Anesthesia; Anesthetics, Intravenous; Animals; Benzoates; Body Temperature; Brain; Cycloleucine; Drug Synergism; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Tetanus; Time Factors; Urethane | 1997 |
Transmitter regulation of plateau properties in turtle motoneurons.
Topics: Animals; Atropine; Baclofen; Benzoates; Calcium Channels; Calcium Channels, L-Type; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarine; Nifedipine; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Turtles | 1998 |
Contribution of metabotropic glutamate receptors to the depression of excitatory postsynaptic potentials during hypoxia.
Topics: Alanine; Animals; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Hypoxia; In Vitro Techniques; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses; Time Factors; Xanthines | 1997 |
Metabotropic glutamate receptors in the rat nucleus accumbens contribute to amphetamine-induced locomotion.
Topics: Amphetamine; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
Trimethyltin stimulates protein kinase C translocation through receptor-mediated phospholipase C activation in PC12 cells.
Topics: Animals; Atropine; Benzoates; Cell Differentiation; Enzyme Activation; Estrenes; Excitatory Amino Acid Antagonists; Glycine; Inositol 1,4,5-Trisphosphate; Kinetics; Muscarinic Antagonists; PC12 Cells; Protein Kinase C; Pyrrolidinones; Rats; Receptors, Metabotropic Glutamate; Trimethyltin Compounds | 1998 |
Evidence for neuronal origin and metabotropic receptor-mediated regulation of extracellular glutamate and aspartate in rat striatum in vivo following electrical stimulation of the prefrontal cortex.
Topics: Animals; Aspartic Acid; Benzoates; Calcium; Corpus Striatum; Cycloleucine; Dicarboxylic Acids; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycine; Male; Neurons; Neurotransmitter Uptake Inhibitors; Prefrontal Cortex; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin; Time Factors | 1998 |
In vivo microdialysis reveals facilitatory metabotropic glutamate receptors regulating excitatory amino acid release in rat nucleus tractus solitarius.
Topics: Animals; Aspartic Acid; Benzoates; Calcium; Chromatography, High Pressure Liquid; Cycloleucine; Excitatory Amino Acid Antagonists; Excitatory Amino Acids; Glutamic Acid; Glycine; Kinetics; Male; Microdialysis; Neurotoxins; Rats; Rats, Inbred WKY; Receptors, Metabotropic Glutamate; Solitary Nucleus; Tetrodotoxin | 1998 |
Characterization of an intracellular alkaline shift in rat astrocytes triggered by metabotropic glutamate receptors.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloro-7-nitrobenzofurazan; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Anti-Bacterial Agents; Astrocytes; Benzoates; Caffeine; Calcium; Cells, Cultured; Chlorides; Cycloleucine; Dicyclohexylcarbodiimide; Enzyme Inhibitors; Glycine; HEPES; Hydrogen-Ion Concentration; Indans; Intracellular Fluid; Ion Transport; Ionomycin; Ionophores; Macrolides; Nigericin; Rats; Receptors, Metabotropic Glutamate; Sodium | 1998 |
(+)-MCPG blocks induction of LTP in CA1 of rat hippocampus via agonist action at an mGluR group II receptor.
Topics: Amino Acids, Dicarboxylic; Animals; Benzoates; Cycloleucine; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuroprotective Agents; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1998 |
Metabotropic glutamate receptors depress glutamate-mediated synaptic input to rat midbrain dopamine neurones in vitro.
Topics: Alanine; Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Male; Mesencephalon; Neurons; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1998 |
Group II and III metabotropic glutamate receptors modulate paired pulse depression in the rat dentate gyrus in vitro.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Cycloleucine; Cyclopropanes; Dentate Gyrus; Evoked Potentials, Somatosensory; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Resorcinols | 1997 |
Evidence for involvement of the cGMP-protein kinase G signaling system in the induction of long-term depression, but not long-term potentiation, in the dentate gyrus in vitro.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Alkaloids; Animals; Benzoates; Carbazoles; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; GTP-Binding Proteins; Guanylate Cyclase; Indoles; Long-Term Potentiation; Neurons; Oxadiazoles; Phosphodiesterase Inhibitors; Protein Kinases; Purinones; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction | 1998 |
Regulation of immediate early gene c-fos and zif/268 mRNA expression in rat striatum by metabotropic glutamate receptor.
Topics: Animals; Benzazepines; Benzoates; Corpus Striatum; Cycloleucine; DNA-Binding Proteins; Dopamine Antagonists; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Glycine; Immediate-Early Proteins; In Situ Hybridization; Male; Microinjections; Neuroprotective Agents; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factors; Zinc Fingers | 1998 |
Evidence for metabotropic glutamate receptor activation in the induction of depolarization-induced suppression of inhibition in hippocampal CA1.
Topics: 4-Aminopyridine; Amino Acids, Dicarboxylic; Animals; Benzoates; Calcium Channels; Cycloleucine; Cyclopropanes; Enzyme Inhibitors; Ethylmaleimide; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Male; Membrane Potentials; Neural Inhibition; Neuroprotective Agents; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Metabotropic Glutamate; Signal Transduction; Synapses | 1998 |
Reduction of sensory and metabotropic glutamate receptor responses in the thalamus by the novel metabotropic glutamate receptor-1-selective antagonist S-2-methyl-4-carboxy-phenylglycine.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cycloleucine; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Male; N-Methylaspartate; Naphthols; Neurons, Afferent; Neuroprotective Agents; Propylene Glycols; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Thalamus | 1998 |
Progression of change in NMDA, non-NMDA, and metabotropic glutamate receptor function at the developing corticothalamic synapse.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Benzoates; Cerebral Cortex; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Mice; Mice, Inbred ICR; Nerve Fibers; Neurons; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Thalamus | 1998 |
Metabotropic glutamate receptor activation modulates sound level processing in the cochlear nucleus.
Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Auditory Pathways; Auditory Perception; Benzoates; Cats; Cochlear Nucleus; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; N-Methylaspartate; Neurons; Neuroprotective Agents; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Inhibition of group I metabotropic glutamate receptors blocks spatial learning in rats.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Maze Learning; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Spatial Behavior | 1998 |
The metabotropic glutamate receptor antagonist (RS)-MCPG produces hyperlocomotion in amphetamine pre-exposed rats.
Topics: Amphetamine; Animals; Benzoates; Central Nervous System Stimulants; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 1998 |
When are class I metabotropic glutamate receptors necessary for long-term potentiation?
Topics: Animals; Benzoates; Calcium; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Intracellular Membranes; Long-Term Potentiation; Male; Microscopy, Confocal; Muscle Contraction; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 1998 |
Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Glycine; Male; Nerve Fibers; Neural Inhibition; Patch-Clamp Techniques; Protein Kinase C; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission; Type C Phospholipases | 1998 |
Effects of metabotropic glutamate receptor block on the synaptic transmission and plasticity in the rat medial vestibular nuclei.
Topics: Animals; Benzoates; Cycloleucine; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Neuronal Plasticity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Vestibular Nuclei | 1998 |
Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures.
Topics: Animals; Astrocytes; Benzoates; Cell Death; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Indans; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Protein Binding; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate | 1998 |
Group I metabotropic glutamate receptors mediate slow inhibition of calcium current in neocortical neurons.
Topics: Animals; Benzoates; Calcium; Calcium Channel Blockers; Cerebral Cortex; Electric Conductivity; Excitatory Amino Acid Antagonists; Glycine; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Regulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Benzoates; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Tetrodotoxin; Trigeminal Nuclei | 1998 |
Slow oscillations (
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Age Factors; Animals; Benzoates; Bicuculline; Cardiovascular Agents; Cesium; Chlorides; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Hippocampus; Interneurons; Male; Membrane Potentials; Neural Pathways; Organ Culture Techniques; Patch-Clamp Techniques; Periodicity; Pyrimidines; Rats; Rats, Wistar; Receptors, GABA-A; Synapses; Temperature; Xanthines | 1998 |
Group I mGluRs modulate calcium currents in rat GP: functional implications.
Topics: Animals; Benzoates; Calcium Channel Blockers; Calcium Channels; Cycloleucine; Electric Conductivity; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Male; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols | 1998 |
Prolonged activation of the N-methyl-D-aspartate receptor-Ca2+ transduction pathway causes spontaneous recurrent epileptiform discharges in hippocampal neurons in culture.
Topics: 2-Amino-5-phosphonovalerate; Animals; Animals, Newborn; Benzoates; Calcium; Cells, Cultured; Dizocilpine Maleate; Egtazic Acid; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Magnesium; Membrane Potentials; Microscopy, Confocal; Neurons; Nifedipine; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 1998 |
Long-term potentiation in vivo increases rat hippocampal tenascin-C expression.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; In Situ Hybridization; Long-Term Potentiation; Male; Nerve Tissue Proteins; Rats; Rats, Wistar; Synaptic Transmission; Tenascin | 1998 |
Metabotropic glutamate receptor agonist (1S,3R-ACPD) increased frontal cortex dopamine release in aged but not in young rats.
Topics: Animals; Benzoates; Cycloleucine; Dopamine; Excitatory Amino Acid Antagonists; Frontal Lobe; Glycine; Male; Microdialysis; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Time Factors | 1998 |
Role of group I metabotropic glutamate receptors in traumatic spinal cord white matter injury.
Topics: Age Factors; Animals; Astrocytes; Benzoates; Cycloleucine; Electrophysiology; Estrenes; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Glycine; Immunohistochemistry; Male; Membrane Potentials; Nerve Fibers; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Spinal Cord; Spinal Cord Injuries; Type C Phospholipases | 1998 |
Glutamate in the nucleus of the solitary tract activates both ionotropic and metabotropic glutamate receptors.
Topics: Animals; Benzoates; Blood Pressure; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Heart Rate; Kynurenic Acid; Lumbosacral Region; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Solitary Nucleus; Sympathetic Nervous System | 1998 |
Activation of metabotropic glutamate receptors is necessary for transneuronal regulation of ribosomes in chick auditory neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Chick Embryo; Cochlea; Cochlear Nerve; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Neurons, Afferent; Receptors, Metabotropic Glutamate; Ribosomes | 1998 |
Sympathoexcitatory neurotransmission of the chemoreflex in the NTS of awake rats.
Topics: Animals; Benzoates; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Microinjections; Quinoxalines; Rats; Rats, Wistar; Reflex; Solitary Nucleus; Sympathetic Nervous System; Synaptic Transmission | 1999 |
P42/44 MAP kinase inhibitor PD98059 attenuates multiple forms of synaptic plasticity in rat dentate gyrus in vitro.
Topics: Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Electrophysiology; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Mitogen-Activated Protein Kinase 1; Naphthols; Neuronal Plasticity; Nickel; Propylene Glycols; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synapses | 1999 |
Membrane potential and intracellular Ca2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons.
Topics: Animals; Benzoates; Calcium; Calcium Signaling; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Image Processing, Computer-Assisted; In Vitro Techniques; Interneurons; Male; Membrane Potentials; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Tetrodotoxin | 1999 |
Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord.
Topics: Amino Acids, Dicarboxylic; Aminobutyrates; Animals; Benzoates; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chlorpromazine; Cycloleucine; Dose-Response Relationship, Drug; Drug Synergism; Egtazic Acid; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; GTP-Binding Proteins; In Vitro Techniques; Kynurenic Acid; Magnesium; Membrane Potentials; Motor Neurons; N-Methylaspartate; Neuroprotective Agents; Pertussis Toxin; Rana pipiens; Receptors, Metabotropic Glutamate; Reflex; Resorcinols; Second Messenger Systems; Spinal Cord; Sulfonamides; Tetrodotoxin; Thapsigargin; Virulence Factors, Bordetella | 1999 |
Long-term suppression of synaptic transmission by tetanization of a single pyramidal cell in the mouse hippocampus in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Bicuculline; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Phosphinic Acids; Propanolamines; Pyramidal Cells; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Induction of long-lasting depression by (+)-alpha-methyl-4-carboxyphenylglycine and other group II mGlu receptor ligands in the dentate gyrus of the hippocampus in vitro.
Topics: Animals; Anticonvulsants; Benzoates; Cyclopropanes; Dentate Gyrus; Dipeptides; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glycine; Hippocampus; In Vitro Techniques; Ligands; Long-Term Potentiation; Neuroprotective Agents; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 1999 |
Evidence that a novel metabotropic glutamate receptor mediates the induction of long-term potentiation at CA1 synapses in the hippocampus.
Topics: Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Anticonvulsant actions of LY 367385 ((+)-2-methyl-4-carboxyphenylglycine) and AIDA ((RS)-1-aminoindan-1,5-dicarboxylic acid).
Topics: Acoustic Stimulation; Animals; Anticonvulsants; Benzoates; Dose-Response Relationship, Drug; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Female; Glycine; Indans; Inferior Colliculi; Male; Mice; Mice, Inbred DBA; Mice, Mutant Strains; Rats; Receptors, Metabotropic Glutamate; Seizures; Sound | 1999 |
Group I metabotropic glutamate receptors mediate phospholipase D stimulation in rat cultured astrocytes.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Carcinogens; Cerebellum; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Neurons; Neuroprotective Agents; Norepinephrine; Phospholipase D; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathomimetics; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1999 |
Expression and signaling of group I metabotropic glutamate receptors in astrocytes and microglia.
Topics: Animals; Astrocytes; Benzoates; Brain; Brain Chemistry; Calcium; Cells, Cultured; Cycloleucine; DNA Primers; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gene Expression; Glutamic Acid; Glycine; In Situ Hybridization; Inositol 1,4,5-Trisphosphate; Microglia; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 1999 |
Glutamate regulates IP3-type and CICR stores in the avian cochlear nucleus.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Alanine; Animals; Benzoates; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Chelating Agents; Chick Embryo; Cochlear Nucleus; Cyclic AMP; Cycloleucine; Cysteine; Egtazic Acid; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Gallic Acid; Glutamic Acid; Glycine; Ibotenic Acid; Inositol 1,4,5-Trisphosphate Receptors; Ion Channel Gating; Neurons; Neuroprotective Agents; Neurotransmitter Agents; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Receptors, Cytoplasmic and Nuclear; Ryanodine; Second Messenger Systems; Thionucleotides | 1999 |
Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 recept
Topics: Animals; Astrocytes; Benzoates; Caudate Nucleus; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fetus; Gerbillinae; Glycine; Ischemic Attack, Transient; Male; Mice; N-Methylaspartate; Necrosis; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiophenes | 1999 |
ACPD-mediated slow-onset potentiation is associated with cell death in the rat CA1 region in vivo.
Topics: Animals; Benzoates; Cell Death; Cell Survival; Cycloleucine; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Male; Neuronal Plasticity; Neuroprotective Agents; Rats; Rats, Wistar | 1999 |
A CaMKII inhibitor, KN-62, facilitates DHPG-induced LTD in the CA1 region of the hippocampus.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Benzoates; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Depression, Chemical; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Rats; Rats, Wistar; Signal Transduction; Synaptic Transmission | 1999 |
Role of glutamate receptor subtypes in the lamprey respiratory network.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Lampreys; Neurons; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Respiration | 1999 |
Cardiovascular response to group I metabotropic glutamate receptor activation in NTS.
Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Kynurenic Acid; Male; Methoxyhydroxyphenylglycol; N-Methylaspartate; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 1999 |
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala.
Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses | 1999 |
Activation of the extracellular signal-regulated kinase 2 by metabotropic glutamate receptors.
Topics: Animals; Benzoates; Calcium-Calmodulin-Dependent Protein Kinases; CHO Cells; Cricetinae; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Glycine; GTP-Binding Proteins; Intracellular Membranes; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Pertussis Toxin; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, Metabotropic Glutamate; Signal Transduction; Virulence Factors, Bordetella | 1999 |
Effects of guanine nucleotides on adenosine and glutamate modulation of cAMP levels in optic tectum slices from chicks.
Topics: Adenosine; Animals; Benzoates; Chickens; Cyclic AMP; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Guanine Nucleotides; In Vitro Techniques; Receptors, Metabotropic Glutamate; Superior Colliculi | 1999 |
Input-and layer-dependent synaptic plasticity in the rat perirhinal cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Long-Term Potentiation; Male; Neocortex; Neuronal Plasticity; Rats; Rats, Wistar; Synaptic Transmission | 1999 |
Transient translocation of protein kinase Cgamma in hippocampal long-term potentiation depends on activation of metabotropic glutamate receptors.
Topics: Animals; Benzoates; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Isoenzymes; Long-Term Potentiation; Male; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Subcellular Fractions | 1999 |
Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Astrocytes; Benzoates; Calcium; Cell Communication; Cells, Cultured; Dinoprostone; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Membrane Potentials; Neuroimmunomodulation; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thapsigargin | 1999 |
Opposite modulation of capsaicin-evoked substance P release by glutamate receptors.
Topics: Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Capsaicin; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Male; Methoxyhydroxyphenylglycol; Nerve Fibers; Nociceptors; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Substance P; Trigeminal Nuclei | 1999 |
Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Carboxypeptidases; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fetus; Glutamate Carboxypeptidase II; Glycine; Methotrexate; N-Methylaspartate; Neurons; Neurotoxins; Organophosphorus Compounds; Potassium Cyanide; Pyrrolidines; Rats | 1999 |
An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus.
Topics: Alkaloids; Animals; Benzoates; Benzophenanthridines; Calcium; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Indoles; Magnesium; Methoxyhydroxyphenylglycol; Neuronal Plasticity; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission; Type C Phospholipases | 1999 |
Regulation of NMDA-stimulated [14C]GABA and [3H]acetylcholine release by striatal glutamate and dopamine receptors.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Carbon Radioisotopes; Corpus Striatum; Cycloleucine; Dopamine Agonists; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Kainic Acid; Male; N-Methylaspartate; Proline; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tritium | 1999 |
The retention deficit induced by (RS)-alpha-methyl-4-carboxyphenylglycine in a lever-press learning task is blocked by selective agonists of either group I or group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cycloleucine; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Learning; Male; Memory Disorders; Mice; Mice, Inbred Strains; Neuroprotective Agents; Protein Isoforms; Receptors, Metabotropic Glutamate; Resorcinols; Retention, Psychology; Time Factors | 1999 |
Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases.
Topics: Animals; Benzoates; Cycloleucine; Dopamine; Electric Stimulation; Enzyme Activation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indans; Kinetics; Male; Mitogen-Activated Protein Kinases; Models, Neurological; Neuronal Plasticity; Phosphoserine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Metabotropic Glutamate | 1999 |
Potentiation of glutamatergic agonist-induced inositol phosphate formation by basic fibroblast growth factor is related to developmental features in hippocampal cultures: neuronal survival and glial cell proliferation.
Topics: Animals; Antimetabolites, Antineoplastic; Benzoates; Cell Division; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloleucine; Cytarabine; Epidermal Growth Factor; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Fibroblast Growth Factor 2; Glutamic Acid; Glycine; Hippocampus; Inositol Phosphates; Neuroglia; Neurons; Neuroprotective Agents; Quinoxalines; Quisqualic Acid; Rats; Receptors, AMPA; Receptors, Kainic Acid; Type C Phospholipases | 1999 |
1-Aminoindan-1,5-dicarboxylic acid and (S)-(+)-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Bridged Bicyclo Compounds; Cell Death; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Indans; Ischemic Attack, Transient; Mice; Neuroprotective Agents; Neurotoxins; Organ Culture Techniques; Pyramidal Cells; Quinoxalines; Receptors, Metabotropic Glutamate; Resorcinols | 1999 |
Role of metabotropic glutamate receptor subclasses in modulation of adenylyl cyclase activity by a nootropic NS-105.
Topics: Adenylyl Cyclases; Animals; Benzoates; Cells, Cultured; Cerebral Cortex; Colforsin; Cyclic AMP; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation; Glycine; Male; Membranes; Neurons; Nootropic Agents; Oligodeoxyribonucleotides, Antisense; Oligonucleotides; Piperidines; Proline; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger | 2000 |
Neuroprotective actions of novel and potent ligands of group I and group II metabotropic glutamate receptors.
Topics: Animals; Benzoates; Bridged Bicyclo Compounds; Cells, Cultured; Cerebral Cortex; Drug Evaluation, Preclinical; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Ischemia; Male; N-Methylaspartate; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Thiophenes | 1999 |
(+/-)-Alpha-methyl-4-carboxyphenylglycine, a metabotropic glutamate receptor blocker, impairs retention of an inhibitory avoidance task in rats when infused into the basolateral nucleus of the amygdala.
Topics: Amygdala; Animals; Avoidance Learning; Benzoates; Electroshock; Emotions; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Microinjections; Neural Inhibition; Nociceptors; Pain Threshold; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Retention, Psychology | 2000 |
Group II metabotropic glutamate receptors are a common target of N-anisoyl-GABA and 1S,3R-ACPD in enhancing ACh release in the prefrontal cortex of freely moving SHRSP.
Topics: Acetylcholine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amino Acids, Dicarboxylic; Animals; Anisoles; Benzoates; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Indans; Male; Microdialysis; Perfusion; Prefrontal Cortex; Quinoxalines; Rats; Rats, Inbred SHR; Receptors, AMPA; Receptors, Metabotropic Glutamate; Thalamic Nuclei; Wakefulness | 2000 |
Neuroprotection by metabotropic glutamate receptor agonists on kainate-induced degeneration of motor neurons in spinal cord slices from adult rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Cell Survival; Choline O-Acetyltransferase; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Situ Nick-End Labeling; In Vitro Techniques; Kainic Acid; Male; Motor Neurons; N-Methylaspartate; Nerve Degeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2000 |
Effects of blockade of metabotropic glutamate receptors in the subthalamic nucleus on haloperidol-induced Parkinsonism in rats.
Topics: Animals; Benzoates; Dopamine Antagonists; Dystonia; Excitatory Amino Acid Antagonists; Glycine; Haloperidol; Male; Microinjections; Parkinson Disease, Secondary; Posture; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Subthalamic Nucleus | 2000 |
High Ca(2+)/low Mg(2+) solution induces long-term depression in rat CA1 pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium; Calcium Channel Blockers; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Magnesium; Neuronal Plasticity; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Sirolimus; Solutions; Tacrolimus; Verapamil | 2000 |
Long-term potentiation of primary afferent neurotransmission at trigeminal synapses of juvenile rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Chelating Agents; Egtazic Acid; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Neurons, Afferent; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Trigeminal Nuclei | 2000 |
(+)-MCPG induces PKCepsilon translocation in cortical synaptosomes through a PLD-coupled mGluR.
Topics: Animals; Benzoates; Cerebral Cortex; Chelating Agents; Cycloleucine; Cyclopropanes; Egtazic Acid; Enzyme Activation; Excitatory Amino Acid Antagonists; Glycine; Isoenzymes; Male; Neurons; Neuroprotective Agents; Phospholipase D; Presynaptic Terminals; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptosomes | 2000 |
Differential expression of group I metabotropic glutamate receptors in functionally distinct hippocampal interneurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Cycloleucine; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression; Glycine; Hippocampus; Interneurons; Neuroprotective Agents; Patch-Clamp Techniques; Periodicity; Picrotoxin; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; Tetrodotoxin | 2000 |
Selective depolarization of interneurons in the early posttraumatic dentate gyrus: involvement of the Na(+)/K(+)-ATPase.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Benzoates; Bicuculline; Brain Injuries; Dentate Gyrus; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; In Vitro Techniques; Interneurons; Membrane Potentials; Patch-Clamp Techniques; Pyrimidines; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Strophanthidin; Tetrodotoxin; Wounds, Nonpenetrating | 2000 |
Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro.
Topics: Animals; Aspartic Acid; Autoreceptors; Benzoates; Calcium; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Indans; Male; Neurons; Phenylacetates; Prosencephalon; Quisqualic Acid; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Tetrodotoxin; Tritium | 2000 |
Induction of homosynaptic long-term depression at spinal synapses of sensory a delta-fibers requires activation of metabotropic glutamate receptors.
Topics: Animals; Benzoates; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Membrane Potentials; Nerve Fibers, Myelinated; Neural Inhibition; Neuronal Plasticity; Neurons, Afferent; Pain; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Synapses | 2000 |
The regulatory connection between the activity of granule cell NMDA receptors and dendritic differentiation of cerebellar Purkinje cells.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Calcium; Cell Count; Cell Differentiation; Cells, Cultured; Dendrites; Excitatory Amino Acid Antagonists; Glycine; Intracellular Fluid; N-Methylaspartate; Nitric Oxide; Purkinje Cells; Rats; Rats, Wistar; Receptor Protein-Tyrosine Kinases; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synaptic Transmission | 2000 |
Group II, but not group I, metabotropic glutamate receptors in the rat nucleus accumbens contribute to amphetamine-induced locomotion.
Topics: Amphetamine; Animals; Behavior, Animal; Benzoates; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Indans; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2000 |
Role of central glutamate receptors, nitric oxide and soluble guanylyl cyclase in the inhibition by endotoxin of rat gastric acid secretion.
Topics: Animals; Benzoates; Cyclic GMP; Dizocilpine Maleate; Dose-Response Relationship, Drug; Endotoxins; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Gastric Acid; Gastric Mucosa; Glycine; Guanylate Cyclase; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Pentagastrin; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Solubility; Stomach; Vagotomy | 2000 |
Calcium mobilization elicited by two types of nicotinic acetylcholine receptors in mouse substantia nigra pars compacta.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Animals; Benzoates; Bungarotoxins; Calcium; Calcium Channel Blockers; Choline; Dihydro-beta-Erythroidine; Endoplasmic Reticulum; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Fura-2; Glycine; In Vitro Techniques; Indoles; Insecticides; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Neurons; Nicotine; Nicotinic Agonists; Nifedipine; Nootropic Agents; Patch-Clamp Techniques; Polyamines; Presynaptic Terminals; Receptors, Nicotinic; Substantia Nigra; Tetrodotoxin; Tyrosine 3-Monooxygenase | 2000 |
Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Age Factors; Animals; Animals, Newborn; Benzoates; Dizocilpine Maleate; Entorhinal Cortex; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Glutamate | 2000 |
Induction of locomotor sensitization by amphetamine requires the activation of NMDA receptors in the rat ventral tegmental area.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Benzoates; Central Nervous System Stimulants; Excitatory Amino Acid Antagonists; Glycine; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Ventral Tegmental Area | 2000 |
Molecular signalling pathways in the cerebral cortex are required for retrieval of one-trial avoidance learning in rats.
Topics: 2-Amino-5-phosphonovalerate; Adenylyl Cyclases; Animals; Avoidance Learning; Benzoates; Cerebral Cortex; Cyclic AMP-Dependent Protein Kinases; Entorhinal Cortex; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Functional Laterality; Glycine; Hippocampus; Injections; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Signal Transduction | 2000 |
Contributions of mGlu1 and mGlu5 receptors to interactions with N-methyl-D-aspartate receptor-mediated responses and nociceptive sensory responses of rat thalamic neurons.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Neurons; Pain Measurement; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus | 2000 |
Quisqualate induces an inward current via mGluR activation in neocortical pyramidal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Bicuculline; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Guanosine Diphosphate; In Vitro Techniques; Membrane Potentials; Neocortex; Patch-Clamp Techniques; Pyramidal Cells; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Tetrodotoxin; Thionucleotides | 2000 |
Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil.
Topics: Animals; Arachidonic Acid; Benzoates; Brain; Brain Ischemia; Cell Survival; Excitatory Amino Acid Antagonists; Gerbillinae; Glycine; Indans; Male; Neurons; Neuroprotective Agents; Prosencephalon; Pyridines; Receptors, Metabotropic Glutamate | 2000 |
A role for protein kinase C in a form of metaplasticity that regulates the induction of long-term potentiation at CA1 synapses of the adult rat hippocampus.
Topics: Alkaloids; Animals; Benzoates; Benzophenanthridines; Cyclic AMP; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Glycine; Hippocampus; In Vitro Techniques; Indoles; Long-Term Potentiation; Neuronal Plasticity; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Thionucleotides | 2000 |
N-acetylaspartylglutamate protects against transient focal cerebral ischemia in rats.
Topics: Animals; Benzoates; Brain; Dipeptides; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Ischemic Attack, Transient; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2000 |
Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma.
Topics: Animals; Benzoates; Brain Injuries; Cell Death; Cells, Cultured; Chromones; Disease Models, Animal; Dizocilpine Maleate; Drug Synergism; Evoked Potentials; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Indans; Injections, Intraventricular; Male; Models, Biological; Neuroprotective Agents; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Wounds, Nonpenetrating | 2001 |
Temperature-dependent separation of a delayed-onset long-lasting enhancement mediated by coactivation of NMDA and metabotropic glutamate receptors following a transient exposure of extracellular high Ca(2+).
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Calcium; Cold Temperature; Cricetinae; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Extracellular Space; Glycine; Hippocampus; In Vitro Techniques; Male; Mesocricetus; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Temperature | 2001 |
Group II metabotropic glutamate receptor activation protects striatal dopaminergic nerve terminals against MPP+-induced neurotoxicity along with brain-derived neurotrophic factor induction.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Benzoates; Brain-Derived Neurotrophic Factor; Corpus Striatum; Cyclopropanes; Disease Models, Animal; Dopamine; Dopamine Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; In Situ Hybridization; Male; Microdialysis; Microglia; MPTP Poisoning; Neurons; Presynaptic Terminals; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger | 2001 |
Stimulation of metabotropic but not ionotropic glutamatergic receptors in the nucleus accumbens is required for the D-amphetamine-induced release of functional dopamine.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics, Opioid; Animals; Benzoates; Brain Chemistry; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; Excitatory Amino Acid Antagonists; Glycine; Hyperkinesis; Male; Morphine; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Ventral Tegmental Area | 2001 |
Activation of metabotropic glutamate receptors induces gamma frequency oscillations in the rat dentate gyrus in vivo.
Topics: Animals; Benzoates; Cycloleucine; Dentate Gyrus; Electroencephalography; Excitatory Amino Acid Antagonists; Glycine; Male; Rats; Receptors, Metabotropic Glutamate; Time Factors | 2001 |
Selective involvement of mGlu1 receptors in corticostriatal LTD.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Male; Mice; Mice, Knockout; Neocortex; Neostriatum; Neuronal Plasticity; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2001 |
Properties of synchronous and asynchronous release during pulse train depression in cultured hippocampal neurons.
Topics: Animals; Antihypertensive Agents; Apamin; Benzoates; Benzothiadiazines; Calcium; Cells, Cultured; Chelating Agents; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Neural Inhibition; Neurons; Nitrobenzoates; Rats; Strontium; Tetraethylammonium | 2001 |
A kainate receptor increases the efficacy of GABAergic synapses.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Benzodiazepines; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; gamma-Aminobutyric Acid; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Kainic Acid; Neurons; Protein Kinase C; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Kainic Acid; Staurosporine; Synapses; Tetradecanoylphorbol Acetate; Tetrodotoxin | 2001 |
A metabotropic glutamate receptor antagonist, alpha-methyl-4-carboxyphenylglycine, attenuates immediate early gene mRNA expression following traumatic injury in cultured rat cortical glial cells.
Topics: Animals; Benzoates; Brain Injuries; Cells, Cultured; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Fetus; Gene Expression Regulation; Genes, Immediate-Early; Gliosis; Glycine; Nerve Regeneration; Neuroglia; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Quinoxalines; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Transcriptional Activation | 2001 |
Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.
Topics: Animals; Benzoates; Calcium; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Neural Inhibition; Patch-Clamp Techniques; Potassium Channels; Pyramidal Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Changes in rat serum corticosterone after treatment with metabotropic glutamate receptor agonists or antagonists.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Amino Acids; Animals; Benzoates; Bridged Bicyclo Compounds; Corticosterone; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Phenylacetates; Propionates; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Xanthenes | 2001 |
Differential roles for glutamate receptor subtypes within commissural NTS in cardiac-sympathetic reflex.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Blood Pressure; Bradykinin; Excitatory Amino Acid Antagonists; Glycine; Heart; Instillation, Drug; Kidney; Male; Microinjections; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Reflex; Solitary Nucleus; Sympathetic Nervous System | 2001 |
Presynaptic modulation by group III metabotropic glutamate receptors (mGluRs) of the excitatory postsynaptic potential mediated by mGluR1 in rat cerebellar Purkinje cells.
Topics: Animals; Benzoates; Bicuculline; Cerebellum; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Male; Purkinje Cells; Quinoxalines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, Presynaptic | 2001 |
Neuroprotection afforded by NAAG and NAALADase inhibition requires glial cells and metabotropic glutamate receptor activation.
Topics: Animals; Benzoates; Carboxypeptidases; Cells, Cultured; Dipeptides; Excitatory Amino Acid Antagonists; Female; Glutamate Carboxypeptidase II; Glycine; Neuroglia; Neuroprotective Agents; Organophosphorus Compounds; Rats; Receptors, Metabotropic Glutamate | 2001 |
Neuronal glutamate transporters control activation of postsynaptic metabotropic glutamate receptors and influence cerebellar long-term depression.
Topics: Amino Acid Transport System X-AG; Animals; Aspartic Acid; ATP-Binding Cassette Transporters; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glutamic Acid; Glycine; Long-Term Potentiation; Nerve Fibers; Neural Inhibition; Organ Culture Techniques; Picrotoxin; Purkinje Cells; Quinoxalines; Rats; Receptors, Metabotropic Glutamate; Synapses; Tetrodotoxin | 2001 |
Endogenous activation of group-I metabotropic glutamate receptors is required for differentiation and survival of cerebellar Purkinje cells.
Topics: Animals; Animals, Newborn; Benzoates; Cell Differentiation; Cell Survival; Cells, Cultured; Cerebellum; Chromones; Dendrites; Drug Administration Routes; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; Oligonucleotides, Antisense; Purkinje Cells; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Thiophenes; Time Factors | 2001 |
Glutamate receptor stimulation induces a persistent rhythmicity of the GABAergic inputs to rat midbrain dopaminergic neurons.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Benzoates; Dopamine; Electrophysiology; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; Gap Junctions; Glycine; Membrane Potentials; Neural Pathways; Neurons; Periodicity; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Substantia Nigra | 2001 |
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Action Potentials; Animals; Anticonvulsants; Benzoates; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Mice; Mice, Knockout; Muscarine; Muscarinic Agonists; N-Methylaspartate; Neostriatum; Neurons; Phenylacetates; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Synaptic Transmission | 2001 |
Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Blood Proteins; Calcium; Calcium Channels; Cell Membrane; Cells, Cultured; Cycloleucine; Cytoplasm; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Genetic Vectors; Glutamic Acid; Glycine; Green Fluorescent Proteins; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Luminescent Proteins; Membrane Potentials; Mice; Mice, Inbred ICR; Neuroprotective Agents; Patch-Clamp Techniques; Phosphoproteins; Purkinje Cells; Receptors, AMPA; Receptors, Metabotropic Glutamate; Sindbis Virus | 2001 |
Group I metabotropic glutamate receptors limit AMPA receptor-mediated oligodendrocyte progenitor cell death.
Topics: Animals; Anti-Anxiety Agents; Benzoates; Benzodiazepines; Cell Death; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kainic Acid; Oligodendroglia; Rats; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols; Stem Cells | 2001 |
Activation of metabotropic glutamate receptor mediates upregulation of transcription factor mRNA expression in rat striatum induced by acute administration of amphetamine.
Topics: Amphetamine; Animals; Behavior, Animal; Benzoates; Central Nervous System Stimulants; Corpus Striatum; DNA-Binding Proteins; Dopamine; Early Growth Response Protein 1; Excitatory Amino Acid Antagonists; Gene Expression; Genes, Immediate-Early; Glycine; Immediate-Early Proteins; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; RNA, Messenger; Transcription Factors | 2002 |
Group I metabotropic glutamate receptor antagonists block secondary thermal hyperalgesia in rats with knee joint inflammation.
Topics: Animals; Arthritis, Experimental; Benzoates; Carrageenan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Hindlimb; Hot Temperature; Hyperalgesia; Kaolin; Male; Microdialysis; Neurons; Pain Measurement; Posterior Horn Cells; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord | 2002 |
Differential roles for mGluR1 and mGluR5 in the persistent prolongation of epileptiform bursts.
Topics: Animals; Benzoates; Convulsants; Dose-Response Relationship, Drug; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Picrotoxin; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Time Factors | 2002 |
In vivo effects of intracortical administration of NMDA and metabotropic glutamate receptors antagonists on neocortical long-term potentiation and conditioned taste aversion.
Topics: 2-Amino-5-phosphonovalerate; Animals; Avoidance Learning; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Long-Term Potentiation; Male; Microinjections; N-Methylaspartate; Neocortex; Piperazines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Taste | 2002 |
Group II metabotropic glutamate receptor activation is required for normal hippocampal mossy fibre development in the rat.
Topics: Animals; Animals, Newborn; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Mossy Fibers, Hippocampal; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Reference Values | 2002 |
Group I metabotropic glutamate receptors in spinal cord injury: roles in neuroprotection and the development of chronic central pain.
Topics: Animals; Benzoates; Chronic Disease; Excitatory Amino Acid Antagonists; Glycine; Hyperalgesia; Locomotion; Male; Neuroprotective Agents; Neurotoxins; Pain; Pain Threshold; Physical Stimulation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Spinal Cord Injuries | 2002 |
Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.
Topics: Benzoates; Crystallography, X-Ray; Dimerization; Excitatory Amino Acid Antagonists; Gadolinium; Glutamic Acid; Glycine; Ligands; Models, Molecular; Molecular Structure; Protein Structure, Tertiary; Receptors, Glutamate | 2002 |
Characterization of an N-terminal secreted domain of the type-1 human metabotropic glutamate receptor produced by a mammalian cell line.
Topics: Amino Acid Sequence; Animals; Benzoates; Binding, Competitive; CHO Cells; Cricetinae; Dimerization; Excitatory Amino Acid Antagonists; Glycine; Glycoside Hydrolases; Glycosylation; GTP-Binding Proteins; Humans; Molecular Sequence Data; Peptide Fragments; Protein Structure, Tertiary; Quisqualic Acid; Receptors, Metabotropic Glutamate; Transfection; Tritium | 2002 |
Completing the corticofugal loop: a visual role for the corticogeniculate type 1 metabotropic glutamate receptor.
Topics: Action Potentials; Animals; Benzoates; Cats; Dendrites; Excitatory Amino Acid Antagonists; Feedback; Geniculate Bodies; Glycine; Iontophoresis; Motion Perception; Neurons; Photic Stimulation; Receptors, Metabotropic Glutamate; Visual Cortex; Visual Pathways; Visual Perception | 2002 |
Metabotropic glutamate receptors in the hippocampus and nucleus accumbens are involved in generating seizure-induced hippocampal gamma waves and behavioral hyperactivity.
Topics: Animals; Behavior, Animal; Benzoates; Electroencephalography; Electrophysiology; Excitatory Amino Acid Antagonists; Glutamates; Glycine; Hippocampus; Hyperkinesis; Injections, Intraventricular; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Seizures | 2002 |
Metabotropic glutamate receptors mediate expression of LTP in slices of rat visual cortex.
Topics: Action Potentials; Animals; Benzoates; Drug Combinations; Electric Stimulation; Excitatory Amino Acid Antagonists; Extracellular Space; Glycine; In Vitro Techniques; Long-Term Potentiation; Picrotoxin; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Theta Rhythm; Trans-Activators; Visual Cortex; Visual Pathways | 2002 |
Inhibition of group I metabotropic glutamate receptor responses in vivo in rats by a new generation of carboxyphenylglycine-like amino acid antagonists.
Topics: Alanine; Animals; Benzoates; Cerebellum; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Inhibitory Concentration 50; Mice; Propionates; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Seizures; Structure-Activity Relationship; Thiophenes; Xanthenes | 2002 |
Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Benzoates; Bicuculline; Epilepsy; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Hippocampus; Isoenzymes; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Phospholipase C beta; Potassium Channel Blockers; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses; Type C Phospholipases | 2002 |
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro.
Topics: Action Potentials; Animals; Apamin; Benzoates; Biological Clocks; Cycloleucine; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membrane Potentials; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Rats; Receptors, Metabotropic Glutamate; Resorcinols; Ventral Tegmental Area | 2002 |
Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells.
Topics: Alkaloids; Animals; Benzoates; Benzophenanthridines; Cerebellum; Cycloleucine; Cysteine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Glutamates; Glycine; Male; Mice; Mice, Inbred AKR; N-Methylaspartate; Neurons; Phenanthridines; Receptors, Glutamate; Sodium-Potassium-Exchanging ATPase | 2002 |
Antagonism of glutamatergic metabotropic receptors in the NTS of awake rats does not affect the gain of the baroreflex.
Topics: Animals; Baroreflex; Benzoates; Blood Pressure; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Heart Rate; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Solitary Nucleus | 2003 |
Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Potentials; Mice; Mice, Knockout; Neocortex; Neostriatum; Patch-Clamp Techniques; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2003 |
Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission.
Topics: Amino Acids, Dicarboxylic; Analysis of Variance; Anesthetics, Local; Animals; Benzoates; Calcium; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Ligands; Male; Microdialysis; Potassium Chloride; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Serotonin; Synaptic Transmission; Tetrodotoxin | 2003 |
Optical imaging of long-term depression in the mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Cerebellar Cortex; Diagnostic Imaging; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Glycine; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred Strains; Mice, Transgenic; Microelectrodes; Olivary Nucleus; Optics and Photonics; Protein Kinase C; Receptors, Metabotropic Glutamate | 2003 |
Associative mossy fibre LTP induced by pairing presynaptic stimulation with postsynaptic hyperpolarization of CA3 neurons in rat hippocampal slice.
Topics: Animals; Animals, Newborn; Anticonvulsants; Benzoates; Chelating Agents; Cyclopropanes; Dialysis; Egtazic Acid; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fibrinolytic Agents; Glycine; Heparin; In Vitro Techniques; Long-Term Potentiation; Membrane Potentials; Mossy Fibers, Hippocampal; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Tetanus | 2003 |
Changes of metabotropic glutamate receptor subtype 1a in diffuse brain injury with secondary brain insults and the effects of 2-methyl-4-carboxyphenylglycine.
Topics: Analysis of Variance; Animals; Benzoates; Blood Pressure; Brain Injuries; Glycine; Male; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2003 |
Blockade of excitatory amino acid transporters in the rat hippocampus results in enhanced activation of group I and group III metabotropic glutamate receptors.
Topics: Animals; Aspartic Acid; Benzoates; Colforsin; Cyclic AMP; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Glycine; Hippocampus; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Methoxyhydroxyphenylglycol; Pyridines; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2003 |
Contribution of spinal glutamatergic mechanisms in heterosegmental antinociception induced by noxious stimulation.
Topics: Animals; Benzoates; Capsaicin; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Isoquinolines; Male; Nociceptors; Pyridines; Quinoxalines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Spinal Cord; Stimulation, Chemical; Substance P | 2003 |
Stereoselective synthesis and preliminary evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist.
Topics: Animals; Benzoates; Binding, Competitive; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Excitatory Amino Acid Antagonists; Glycine; Indicators and Reagents; Molecular Conformation; Rats; Receptors, Metabotropic Glutamate; Stereoisomerism; Thiophenes | 2004 |
In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands.
Topics: Amino Acids; Animals; Anticonvulsants; Benzoates; Bridged Bicyclo Compounds, Heterocyclic; Cyclopropanes; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Ligands; Limbic System; Male; Microdialysis; Pilocarpine; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures | 2004 |
Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestin- and clathrin-dependent and is suppressed by receptor inverse agonists.
Topics: Animals; Arrestin; Benzoates; Cell Line; Cell Membrane; Chromones; Clathrin; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Inositol Phosphates; Kidney; Naphthalenes; Protein Isoforms; Protein Transport; Rats; Receptors, Metabotropic Glutamate | 2004 |
Excitation of cerebellar interneurons by group I metabotropic glutamate receptors.
Topics: Action Potentials; Animals; Benzoates; Cerebellum; Glycine; In Vitro Techniques; Interneurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols | 2004 |
Desensitization and internalization of metabotropic glutamate receptor 1a following activation of heterologous Gq/11-coupled receptors.
Topics: Arrestins; Benzoates; beta-Adrenergic Receptor Kinases; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Endocytosis; Glutamic Acid; Glycine; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Phosphoproteins; Protein Binding; Protein Kinase C; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate | 2004 |
Group I metabotropic glutamate receptors interfere in different ways with pentylenetetrazole seizures, kindling, and kindling-related learning deficits.
Topics: Animals; Avoidance Learning; Behavior, Animal; Benzoates; Binding Sites; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsies, Myoclonic; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kindling, Neurologic; Learning Disabilities; Male; Pentylenetetrazole; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Time Factors | 2004 |
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Animals; Benzoates; Chromones; Dendrites; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyramidal Cells; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Sirolimus; Synaptosomes; Tacrolimus; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
The metabotropic glutamate receptor 5 is necessary for late-phase long-term potentiation in the hippocampal CA1 region.
Topics: Animals; Animals, Newborn; Benzoates; Dendrites; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Long-Term Potentiation; Neurons; Phosphorylation; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Ribosomal Protein S6 Kinases, 70-kDa; Threonine; Time Factors | 2004 |
Comparison of metabotropic glutamate receptor responses at segmental and descending inputs to motoneurons in neonatal rat spinal cord.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Benzoates; Brain-Derived Neurotrophic Factor; Cycloleucine; Electric Stimulation; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Membrane Potentials; Motor Neurons; Neurotrophin 3; Patch-Clamp Techniques; Phosphinic Acids; Rats; Receptors, Metabotropic Glutamate; Spinal Cord; Spinal Nerve Roots | 2005 |
Glutamatergic neurotransmission modulates hypoxia-induced hyperventilation but not anapyrexia.
Topics: Animals; Benzoates; Body Temperature; Body Temperature Regulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hyperventilation; Hypoxia; Injections, Intraventricular; Kynurenic Acid; Male; Rats; Rats, Wistar | 2004 |
Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanisms.
Topics: Analysis of Variance; Animals; Benzoates; Dentate Gyrus; Dose-Response Relationship, Drug; Electric Stimulation; Glycine; Long-Term Potentiation; Male; Maze Learning; Rats; Rats, Wistar; Receptors, Glutamate; Receptors, Metabotropic Glutamate; Time Factors; Wakefulness | 2005 |
Glutamatergic receptors of the rostral ventrolateral medulla are involved in the ventilatory response to hypoxia.
Topics: Animals; Benzoates; Body Temperature; Body Temperature Regulation; Drug Interactions; Excitatory Amino Acid Antagonists; Glycine; Hyperventilation; Hypothermia; Hypoxia; Kynurenic Acid; Male; Medulla Oblongata; Microinjections; Pulmonary Ventilation; Rats; Rats, Wistar; Receptors, Glutamate; Tidal Volume; Time Factors; Ventilators, Mechanical | 2005 |
Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Analysis of Variance; Animals; Benzazepines; Benzoates; Blotting, Western; Calcium; Cells, Cultured; Corpus Striatum; Dicarboxylic Acids; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fluorescent Antibody Technique; Glycine; Methoxyhydroxyphenylglycol; Mitogen-Activated Protein Kinase 1; Models, Biological; Neurons; Phenylacetates; Phosphorylation; Pregnancy; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; Transfection | 2005 |
Periaqueductal grey CB1 cannabinoid and metabotropic glutamate subtype 5 receptors modulate changes in rostral ventromedial medulla neuronal activities induced by subcutaneous formalin in the rat.
Topics: Action Potentials; Analgesics; Animals; Benzoates; Benzoxazines; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Injections, Subcutaneous; Male; Medulla Oblongata; Morpholines; Naphthalenes; Neurons; Pain Measurement; Periaqueductal Gray; Piperidines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Reaction Time; Receptor, Cannabinoid, CB1; Receptors, Metabotropic Glutamate; Rimonabant | 2005 |
Repeated administration of group I mGluR antagonists prevents seizure-induced long-term aberrations in hippocampal synaptic plasticity.
Topics: Analysis of Variance; Animals; Benzoates; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Pentylenetetrazole; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures; Time Factors | 2005 |
Group I metabotropic glutamate receptors reduce excitotoxic injury and may facilitate neurogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzoates; Cell Count; Cell Death; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Estrenes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Glycine; Hippocampus; Immunohistochemistry; In Vitro Techniques; Methoxyhydroxyphenylglycol; Models, Biological; N-Methylaspartate; Nerve Tissue Proteins; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Propidium; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate | 2005 |
Role of peripheral group I and II metabotropic glutamate receptors in IL-1beta-induced mechanical allodynia in the orofacial area of conscious rats.
Topics: Air; Animals; Benzoates; Chromones; Consciousness; Excitatory Amino Acid Antagonists; Facial Pain; Functional Laterality; Glycine; Injections, Subcutaneous; Interleukin-1; Male; Nociceptors; Pain Measurement; Pain Threshold; Physical Stimulation; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate | 2005 |
Signal transduction pathways of group I metabotropic glutamate receptor-induced long-term depression at sensory spinal synapses.
Topics: Animals; Benzoates; Calcium; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; Glycine; Intracellular Space; Long-Term Synaptic Depression; Male; Neurons, Afferent; Nociceptors; Patch-Clamp Techniques; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Signal Transduction; Spinal Cord; Synapses; Thapsigargin | 2005 |
Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cadmium Chloride; Calcium; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamates; Glycine; In Vitro Techniques; Kainic Acid; Membrane Potentials; Mice; Mice, Knockout; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Protein Subunits; Receptors, Kainic Acid; Substantia Gelatinosa | 2005 |
The inhibition of glycogen synthase kinase 3beta by a metabotropic glutamate receptor 5 mediated pathway confers neuroprotection to Abeta peptides.
Topics: Amyloid beta-Peptides; Animals; Benzoates; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; In Vitro Techniques; Indoles; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Morpholines; Neurons; Oncogene Protein v-akt; Peptide Fragments; Phosphorylation; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; Serine; Signal Transduction | 2005 |
Down-regulation of metabotropic glutamate receptor 1alpha in globus pallidus and substantia nigra of parkinsonian monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Behavior, Animal; Benzoates; Cell Count; Disease Models, Animal; Down-Regulation; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Glycine; Immunohistochemistry; Indans; Macaca fascicularis; Male; Methoxyhydroxyphenylglycol; Parkinsonian Disorders; Receptors, Metabotropic Glutamate; Severity of Illness Index; Substantia Nigra; Tyrosine 3-Monooxygenase | 2005 |
Olfactory nerve-evoked, metabotropic glutamate receptor-mediated synaptic responses in rat olfactory bulb mitral cells.
Topics: Amino Acids; Animals; Aspartic Acid; Benzoates; Dopamine D2 Receptor Antagonists; Electrophysiology; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA-B Receptor Antagonists; Glutamic Acid; Glycine; In Vitro Techniques; Male; Neuronal Plasticity; Neurons, Afferent; Odorants; Olfactory Bulb; Olfactory Nerve; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Synapses; Tacrine; Xanthenes | 2006 |
mGluR1/5 subtype-specific calcium signalling and induction of long-term potentiation in rat hippocampal oriens/alveus interneurones.
Topics: Animals; Benzoates; Calcium; Calcium Signaling; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Interneurons; Long-Term Potentiation; Membrane Potentials; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols; src-Family Kinases; Synapses; Synaptic Transmission; TRPC Cation Channels | 2006 |
Group I mGlu receptor stimulation inhibits activation-induced cell death of human T lymphocytes.
Topics: Apoptosis; Benzoates; Cells, Cultured; Fas Ligand Protein; Glutamic Acid; Glycine; Humans; Lymphocyte Activation; Receptors, Metabotropic Glutamate; RNA, Messenger; T-Lymphocytes | 2006 |
Nucleus- and species-specific properties of the slow (<1 Hz) sleep oscillation in thalamocortical neurons.
Topics: Action Potentials; Animals; Benzoates; Cats; Cerebral Cortex; Cycloleucine; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Periodicity; Rats; Rats, Wistar; Sleep Stages; Species Specificity; Thalamic Nuclei | 2006 |
Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.
Topics: Animals; Animals, Newborn; Anisomycin; Benzoates; Blotting, Western; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Fragile X Mental Retardation Protein; Glycine; In Vitro Techniques; Leupeptins; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Microtubule-Associated Proteins; Models, Biological; Proteasome Endopeptidase Complex; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; Receptors, Metabotropic Glutamate; RNA, Messenger; Signal Transduction | 2006 |
Peripheral mGluR5 antagonist attenuated craniofacial muscle pain and inflammation but not mGluR1 antagonist in lightly anesthetized rats.
Topics: Anesthetics, Local; Animals; Behavior, Animal; Benzoates; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Facial Muscles; Facial Pain; Functional Laterality; Glycine; Inflammation; Lidocaine; Male; Mustard Plant; Pain Measurement; Plant Oils; Pyridines; Rats; Rats, Sprague-Dawley | 2006 |
The mGlu1 antagonist CPCCOEt enhances the climbing fibre response in Purkinje neurones independently of glutamate receptors.
Topics: Animals; Animals, Newborn; Benzoates; Cerebellum; Chromones; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; In Vitro Techniques; Nerve Fibers; Patch-Clamp Techniques; Purkinje Cells; Pyrimidines; Rats | 2007 |
Recurrent dendrodendritic inhibition of accessory olfactory bulb mitral cells requires activation of group I metabotropic glutamate receptors.
Topics: Animals; Benzoates; Dendrites; Dose-Response Relationship, Drug; Glycine; Inhibitory Postsynaptic Potentials; Methoxyhydroxyphenylglycol; Mice; Neural Inhibition; Olfactory Bulb; Receptors, Metabotropic Glutamate; Time Factors | 2007 |
Differential roles of hippocampal metabotropic glutamate receptors 1 and 5 in inhibitory avoidance learning.
Topics: Animals; Avoidance Learning; Benzoates; Excitatory Amino Acid Antagonists; Extinction, Psychological; Glycine; Hippocampus; Male; Neural Inhibition; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Retention, Psychology | 2007 |
Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo.
Topics: Animals; Benzoates; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Male; Molecular Structure; Nerve Degeneration; Neural Pathways; Neuroprotective Agents; Neurotoxins; Oxidopamine; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substantia Nigra; Treatment Outcome; Tyrosine 3-Monooxygenase | 2007 |
Membrane estrogen receptor-alpha interactions with metabotropic glutamate receptor 1a modulate female sexual receptivity in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzoates; Drug Interactions; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Excitatory Amino Acid Antagonists; Female; Fulvestrant; Glycine; Male; Methoxyhydroxyphenylglycol; Microinjections; Ovariectomy; Preoptic Area; Protein Transport; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Receptors, Opioid, mu; Sexual Behavior, Animal | 2007 |
Developmental decrease in short-term facilitation at Schaffer collateral synapses in hippocampus is mGluR1 sensitive.
Topics: Action Potentials; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzoates; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Phosphinic Acids; Piperidines; Propanolamines; Pyrazoles; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Synapses; Temperature | 2008 |
Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus.
Topics: Animals; Benzoates; Electrophysiology; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Interneurons; Long-Term Potentiation; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Patch-Clamp Techniques; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synapses | 2008 |
A role for protein kinase A and protein kinase M zeta in muscarinic acetylcholine receptor-initiated persistent synaptic enhancement in rat hippocampus in vivo.
Topics: Animals; Benzoates; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Data Interpretation, Statistical; Diamines; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Long-Term Potentiation; Male; Parasympatholytics; Protein Kinase C; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, G-Protein-Coupled; Receptors, Metabotropic Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Synapses; Synaptic Transmission; Thionucleotides | 2008 |
mGluR1 antagonist decreases tyrosine phosphorylation of NMDA receptor and attenuates infarct size after transient focal cerebral ischemia.
Topics: Animals; Benzoates; Cerebral Infarction; Excitatory Amino Acid Antagonists; Glycine; Ischemic Attack, Transient; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2008 |
Dopamine D1 receptors and group I metabotropic glutamate receptors contribute to the induction of long-term potentiation in the nucleus accumbens.
Topics: Animals; Aspartic Acid; Benzazepines; Benzoates; Bicuculline; Dopamine Antagonists; Dose-Response Relationship, Radiation; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; In Vitro Techniques; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Nucleus Accumbens; Phosphinic Acids; Propanolamines; Pyridines; Receptors, Dopamine D1; Receptors, Metabotropic Glutamate; Sulpiride | 2008 |
Activation of group I metabotropic glutamate receptors induces long-term depression in the hippocampal CA1 region of adult rats in vitro.
Topics: Age Factors; Aging; Animals; Axons; Benzoates; Electric Stimulation; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Hippocampus; Long-Term Synaptic Depression; Neural Inhibition; Neural Pathways; Neurons; Organ Culture Techniques; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Synaptic Membranes; Synaptic Transmission | 2008 |
Impact of protein kinase C activation on epileptiform activity in the hippocampal slice.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Benzoates; Benzophenanthridines; Enzyme Activation; Epilepsy; Glutamic Acid; Glycine; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurotransmitter Agents; Phorbol 12,13-Dibutyrate; Picrotoxin; Protein Kinase C; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Signal Transduction | 2008 |
Odor-induced persistent discharge of mitral cells in the mouse olfactory bulb.
Topics: Action Potentials; Animals; Benzoates; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Neural Inhibition; Odorants; Olfactory Bulb; Olfactory Pathways; Receptors, Metabotropic Glutamate; Respiration; Sensory Receptor Cells; Statistics, Nonparametric; Stimulation, Chemical; Synapses | 2009 |
Long-term potentiation of the responses to parallel fiber stimulation in mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Biophysics; Cerebellar Cortex; Diagnostic Imaging; Dose-Response Relationship, Drug; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glycine; Long-Term Potentiation; Male; Mice; Mice, Inbred Strains; Nerve Fibers; Optics and Photonics; Purkinje Cells; Pyridazines; Quinoxalines | 2009 |
Excitatory actions of noradrenaline and metabotropic glutamate receptor activation in granule cells of the accessory olfactory bulb.
Topics: Action Potentials; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzoates; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Norepinephrine; Olfactory Bulb; Phenylephrine; Prazosin; Receptors, Adrenergic, alpha-1; Receptors, Metabotropic Glutamate; Resorcinols | 2009 |
Distinct modes of modulation of GABAergic transmission by Group I metabotropic glutamate receptors in rat entorhinal cortex.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Benzoates; Cardiotonic Agents; Cyclopropanes; Entorhinal Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agents; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Methoxyhydroxyphenylglycol; Neural Inhibition; Neurons; Patch-Clamp Techniques; Phenylacetates; Potassium Channel Blockers; Pyrimidines; Rats; Receptors, Metabotropic Glutamate; Signal Transduction; Synaptic Transmission; Tetraethylammonium | 2010 |
An interaction of oxytocin receptors with metabotropic glutamate receptors in hypothalamic astrocytes.
Topics: Animals; Astrocytes; Benzoates; Calcium; Cells, Cultured; Estradiol; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; Hypothalamus; Oxytocin; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Receptors, Oxytocin; Resorcinols; Signal Transduction; Time Factors | 2009 |
Estradiol-induced estrogen receptor-alpha trafficking.
Topics: Animals; Astrocytes; Benzoates; Biotinylation; Calcium; Cells, Cultured; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogens; Excitatory Amino Acid Antagonists; Extracellular Fluid; Female; Fulvestrant; Gene Expression Regulation; Glycine; Hypothalamus; Mice; Mice, Inbred C57BL; Mice, Knockout; Protein Transport; Rats; Rats, Long-Evans; Receptors, Metabotropic Glutamate; Steroids; Time Factors | 2009 |
Modulators of metabotropic glutamate receptors microinfused into perirhinal cortex: anticonvulsant effects in rats challenged with soman.
Topics: Animals; Anticonvulsants; Benzoates; Cyclopropanes; Dose-Response Relationship, Drug; Glycine; Infusion Pumps; Male; Microinjections; Pyridines; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Seizures; Soman; Temporal Lobe; Time Factors | 2010 |
[Activation of mGluRI in neutrophils promotes the adherence of neutrophils to endothelial cells].
Topics: Benzoates; CD11a Antigen; Cell Adhesion; Endothelial Cells; Glycine; Human Umbilical Vein Endothelial Cells; Humans; Neutrophils; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Resorcinols | 2010 |
mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia.
Topics: Animals; Benzoates; Cell Membrane; Cerebral Cortex; Cytosol; Glycine; Ischemic Attack, Transient; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Phosphoproteins; Protein Kinase C; Protein Kinase C-delta; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; src-Family Kinases; Superoxides; Time Factors | 2010 |
Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury.
Topics: Amino Acid Transport System y+; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Benzoates; Carbon Isotopes; Cell Death; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cystine; Dactinomycin; Dose-Response Relationship, Drug; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Fusion Regulatory Protein 1, Light Chains; Gene Expression Regulation; Glycine; Interleukin-1beta; L-Lactate Dehydrogenase; Mice; Microglia; Neurons; Protein Synthesis Inhibitors; RNA, Messenger; Time Factors | 2010 |
NMDA receptor, PKC and ERK prevent fos expression induced by the activation of group I metabotropic glutamate receptors in the spinal trigeminal subnucleus oralis.
Topics: Animals; Benzoates; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Glycine; Indoles; Male; Maleimides; Neurons; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Resorcinols; Trigeminal Nucleus, Spinal | 2010 |
Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.
Topics: Animals; Benzoates; Calcium; Cells, Cultured; Female; Glycine; HEK293 Cells; Humans; Immunoblotting; Laminin; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurites; Neurons; Protein Binding; PrPC Proteins; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Type C Phospholipases | 2011 |
Endocannabinoids potentiate synaptic transmission through stimulation of astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Benzoates; Biophysics; Calcium; Cannabinoid Receptor Modulators; Chelating Agents; Drug Interactions; Egtazic Acid; Electric Stimulation; Endocannabinoids; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Patch-Clamp Techniques; Photolysis; Piperidines; Pyramidal Cells; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Resorcinols; Synaptic Transmission; Thapsigargin | 2010 |
Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior.
Topics: Amygdala; Analysis of Variance; Animals; Antioxidants; Benzoates; Cyclic AMP-Dependent Protein Kinases; Cyclic N-Oxides; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Extracellular Signal-Regulated MAP Kinases; Glycine; Inositol 1,4,5-Trisphosphate; Macrocyclic Compounds; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxazoles; Pain; Pain Measurement; Pain Perception; Patch-Clamp Techniques; Pyridines; Reactive Oxygen Species; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Signal Transduction; Spin Labels; Superoxides; Thiazoles; Vocalization, Animal | 2011 |
Synaptic activation of mGluR1 generates persistent depression of a fast after-depolarizing potential in CA3 pyramidal neurons.
Topics: Action Potentials; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Synapses | 2011 |
Parasagittally aligned, mGluR1-dependent patches are evoked at long latencies by parallel fiber stimulation in the mouse cerebellar cortex in vivo.
Topics: Animals; Benzoates; Calcium; Cerebellar Cortex; Electric Stimulation; Estrenes; Evoked Potentials; Glycine; Long-Term Potentiation; Male; Mice; Mice, Inbred Strains; Models, Animal; Nerve Fibers; Purkinje Cells; Pyrrolidinones; Quinoxalines; Receptors, AMPA; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Ryanodine; Valine | 2011 |
Activation of group I metabotropic glutamate receptors modulates locomotor-related motoneuron output in mice.
Topics: Action Potentials; Animals; Animals, Newborn; Benzoates; Glycine; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Motor Activity; Motor Neurons; Receptors, Metabotropic Glutamate | 2011 |
Group I mGluR agonist-evoked long-term potentiation in hippocampal oriens interneurons.
Topics: Animals; Benzoates; Electric Stimulation; Electrodes, Implanted; Electrophysiological Phenomena; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Interneurons; Long-Term Potentiation; Male; Phenylacetates; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Resorcinols | 2011 |
Astrocytes display complex and localized calcium responses to single-neuron stimulation in the hippocampus.
Topics: Action Potentials; Analysis of Variance; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Bacterial Proteins; Benzoates; Benzoxazines; Calcium; Calcium Channel Blockers; Carbenoxolone; Channelrhodopsins; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Glial Fibrillary Acidic Protein; Glycine; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Models, Biological; Morpholines; Naphthalenes; Neurons; Patch-Clamp Techniques; Peptide Fragments; Phosphopyruvate Hydratase; Photic Stimulation; Piperidines; Pyrazoles; Pyridines; Sodium Channel Blockers; Statistics, Nonparametric; Tetanus Toxin; Tetrodotoxin; Transduction, Genetic | 2011 |
Contribution of excitatory amino acid receptors of the retrotrapezoid nucleus to the sympathetic chemoreflex in rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Hypercapnia; Male; Phrenic Nerve; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Respiratory Center; Splanchnic Nerves | 2011 |
Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors.
Topics: Action Potentials; Animals; Arthritis, Experimental; Benzoates; Bicuculline; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Methoxyhydroxyphenylglycol; Neurons; Pain; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate | 2011 |
Rescue of synaptic plasticity and spatial learning deficits in the hippocampus of Homer1 knockout mice by recombinant Adeno-associated viral gene delivery of Homer1c.
Topics: Animals; Behavior, Animal; Benzoates; Carrier Proteins; Gene Transfer Techniques; Glycine; Hippocampus; Homer Scaffolding Proteins; Maze Learning; Mice; Mice, Knockout; Neuronal Plasticity; Pyridines; Receptors, Metabotropic Glutamate; Recognition, Psychology; Social Behavior; Synapses | 2012 |
Molecular changes associated with hippocampal long-lasting depression induced by the serine protease subtilisin-A.
Topics: Animals; Anisomycin; Benzoates; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glycine; Hippocampus; Long-Term Synaptic Depression; Male; Mice; Phosphoprotein Phosphatases; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; rhoB GTP-Binding Protein; Subtilisins | 2011 |
Differential involvement of mGluR1 and mGluR5 in memory reconsolidation and retrieval in a passive avoidance task in 1-day old chicks.
Topics: Animals; Animals, Newborn; Avoidance Learning; Benzoates; Boron Compounds; Chickens; Glycine; Male; Memory; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2012 |
The functional role of ascending nociceptive control in defensive behavior.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Glycine; Immobility Response, Tonic; Male; Motor Activity; Neural Pathways; Nociception; Nucleus Accumbens; Pain; Quinoxalines; Rats; Rats, Wistar; Somatostatin | 2012 |
Electrophysiological and behavioral effects of group I metabotropic glutamate receptors on pallidal neurons in rats.
Topics: Action Potentials; Animals; Benzoates; Dopamine Antagonists; Drug Interactions; Excitatory Amino Acid Antagonists; Globus Pallidus; Glycine; Haloperidol; Male; Methoxyhydroxyphenylglycol; Movement; Neurons; Pyridines; Rats; Rats, Wistar; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2012 |
Neuroprotective effects of NMDA and group I metabotropic glutamate receptor antagonists against neurodegeneration induced by homocysteine in rat hippocampus: in vivo study.
Topics: Animals; Apoptosis; Benzoates; Cell Survival; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; Homocysteine; Male; Memantine; Necrosis; Neuroprotective Agents; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2013 |
Dopamine triggers heterosynaptic plasticity.
Topics: Analysis of Variance; Animals; Benzoates; Channelrhodopsins; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electric Stimulation; GABAergic Neurons; Genetic Vectors; Glycine; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Synaptic Depression; Male; Nucleus Accumbens; Optogenetics; Phosphinic Acids; Photic Stimulation; Propanolamines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Synapses; Time Factors; Transduction, Genetic; Tyrosine 3-Monooxygenase; Ventral Tegmental Area | 2013 |
Inhibition of the group I mGluRs reduces acute brain damage and improves long-term histological outcomes after photothrombosis-induced ischaemia.
Topics: Animals; Antimetabolites, Antineoplastic; Astrocytes; Benzoates; Blotting, Western; Brain; Brain Ischemia; Bromodeoxyuridine; Cell Death; Cell Proliferation; Cerebral Infarction; Excitatory Amino Acid Antagonists; Glycine; Immunohistochemistry; In Situ Nick-End Labeling; Intracranial Thrombosis; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neuroglia; Pyridines; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate | 2013 |
Patterned high-frequency stimulation induces a form of long-term depression dependent on GABAA and mACh receptors in the hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anisomycin; Benzoates; CA1 Region, Hippocampal; Electric Stimulation; Electrophysiological Phenomena; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Glycine; Hippocampus; Long-Term Potentiation; Male; Neuronal Plasticity; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, GABA-A | 2013 |
The memory-enhancing effects of hippocampal estrogen receptor activation involve metabotropic glutamate receptor signaling.
Topics: Analysis of Variance; Animals; Benzoates; Caveolin 1; Cyclodextrins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Female; Glycine; Hippocampus; Immunoprecipitation; Immunoproliferative Disorders; Infusions, Intraventricular; Memory; Mice; Mice, Inbred C57BL; Nitriles; Phenols; Phosphorylation; Pyrazoles; Receptors, Estrogen; Signal Transduction | 2013 |
Extracellular calcium modulates actions of orthosteric and allosteric ligands on metabotropic glutamate receptor 1α.
Topics: Allosteric Regulation; Amino Acid Substitution; Benzoates; Binding Sites; Calcium; Calcium Signaling; Carbamates; Excitatory Amino Acid Agonists; Glycine; HEK293 Cells; Humans; Mutation, Missense; Protein Structure, Tertiary; Quisqualic Acid; Receptors, Metabotropic Glutamate; Xanthenes | 2014 |
Function of mGlu1 receptors in the modulation of nociceptive processing in the thalamus.
Topics: Action Potentials; Animals; Benzoates; Carbamates; Cold Temperature; Excitatory Amino Acid Agents; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hot Temperature; Male; Neural Pathways; Neurons; Nociception; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Resorcinols; Somatosensory Cortex; Thalamus; Xanthenes | 2014 |
A protein synthesis-dependent mechanism sustains calcium-permeable AMPA receptor transmission in nucleus accumbens synapses during withdrawal from cocaine self-administration.
Topics: Animals; Benzoates; Calcium; Cocaine-Related Disorders; Cycloheximide; Excitatory Amino Acid Antagonists; Glycine; Male; Methoxyhydroxyphenylglycol; Nucleus Accumbens; Patch-Clamp Techniques; Protein Biosynthesis; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Self Administration; Substance Withdrawal Syndrome; Synapses; Synaptic Transmission; Thiazoles; Ventral Tegmental Area | 2014 |
mGluR5 Upregulation increases excitability of hypothalamic presympathetic neurons through NMDA receptor trafficking in spontaneously hypertensive rats.
Topics: Animals; Benzoates; Blood Pressure; Excitatory Amino Acid Antagonists; Glycine; Male; Medulla Oblongata; Membrane Potentials; Neurons; Paraventricular Hypothalamic Nucleus; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Up-Regulation | 2014 |
Third trimester-equivalent ethanol exposure does not alter complex spikes and climbing fiber long-term depression in cerebellar Purkinje neurons from juvenile rats.
Topics: Animals; Animals, Newborn; Benzoates; Cerebellum; Ethanol; Excitatory Amino Acid Antagonists; Glycine; Male; Patch-Clamp Techniques; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission | 2014 |
Role of group I metabotropic glutamate receptors, mGluR1/mGluR5, in connexin43 phosphorylation and inhibition of gap junctional intercellular communication in H9c2 cardiomyoblast cells.
Topics: Animals; Benzoates; Cell Communication; Connexin 43; Gap Junctions; Glycine; Heart Ventricles; MAP Kinase Kinase 1; Methoxyhydroxyphenylglycol; Myoblasts; Myocytes, Cardiac; Phosphorylation; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Sympathetic Nervous System | 2015 |
Acute food deprivation enhances fear extinction but inhibits long-term depression in the lateral amygdala via ghrelin signaling.
Topics: Acoustic Stimulation; Amygdala; Animals; Benzoates; Corticosterone; Excitatory Amino Acid Antagonists; Exploratory Behavior; Extinction, Psychological; Fear; Food Deprivation; Ghrelin; Glycine; In Vitro Techniques; Long-Term Synaptic Depression; Male; Maze Learning; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Signal Transduction | 2016 |
Ionizing Radiation Induces Altered Neuronal Differentiation by mGluR1 through PI3K-STAT3 Signaling in C17.2 Mouse Neural Stem-Like Cells.
Topics: Animals; Benzoates; Biomarkers; Cell Differentiation; Cell Line; Female; Gene Expression Profiling; Gene Expression Regulation; Glycine; Immunohistochemistry; Mice, Inbred C57BL; Nerve Growth Factors; Neural Stem Cells; Neurites; Neurons; Phosphatidylinositol 3-Kinases; Radiation, Ionizing; Real-Time Polymerase Chain Reaction; Receptors, GABA; Receptors, Metabotropic Glutamate; Signal Transduction; STAT3 Transcription Factor; Synaptophysin; Synaptotagmins; Tumor Suppressor Protein p53 | 2016 |
Selective inhibition of metabotropic glutamate type 1 alpha receptor (mGluR1α) reduces cell proliferation and migration following status epilepticus in early development.
Topics: Age Factors; Animals; Animals, Newborn; Benzoates; Brain; Cell Cycle; Cell Movement; Cell Proliferation; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Glycine; Kainic Acid; Lateral Ventricles; Male; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Rhodamines; Status Epilepticus; Time Factors | 2016 |
A slow excitatory postsynaptic current mediated by a novel metabotropic glutamate receptor in CA1 pyramidal neurons.
Topics: Animals; Benzoates; CA1 Region, Hippocampal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Glycine; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Vesicular Glutamate Transport Protein 1 | 2017 |
Ambient Glutamate Promotes Paroxysmal Hyperactivity in Cortical Pyramidal Neurons at Amyloid Plaques via Presynaptic mGluR1 Receptors.
Topics: Animals; Benzoates; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Glycine; Mice, Inbred C57BL; Neurons; Plaque, Amyloid; Pyramidal Cells; Receptors, Metabotropic Glutamate; Receptors, Presynaptic; Synaptic Transmission | 2017 |
mGlu1 tonically regulates levels of calcium-permeable AMPA receptors in cultured nucleus accumbens neurons through retinoic acid signaling and protein translation.
Topics: Animals; Benzoates; Calcium; Cells, Cultured; Excitatory Amino Acid Antagonists; Female; Glycine; Methoxyhydroxyphenylglycol; Mice; Mice, 129 Strain; Mice, Transgenic; Neurons; Nucleus Accumbens; Pregnancy; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Metabotropic Glutamate; Signal Transduction; Tretinoin | 2019 |