Compounds > alpha-methyl-4-carboxyphenylglycine

alpha-methyl-4-carboxyphenylglycine and 4-carboxy-3-hydroxyphenylglycine

alpha-methyl-4-carboxyphenylglycine has been researched along with 4-carboxy-3-hydroxyphenylglycine in 17 studies

Research

Studies (17)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (76.47)	18.2507
2000's	4 (23.53)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Costantino, G; Jakobsen, P; Kanstrup, A; Lombardi, G; Luneia, R; Marinozzi, M; Moroni, F; Natalini, B; Pellicciari, R; Thomsen, C	1
Bräuner-Osborne, H; Egebjerg, J; Krogsgaard-Larsen, P; Madsen, U; Nielsen, EO	1
Costantino, G; Pellicciari, R	1
Cavanni, P; Eistetter, H; Ferraguti, F; Ratti, E; Salvagno, C; Trist, DG	1
Batchelor, AM; Garthwaite, J; Madge, DJ	1
Eaton, SA; Salt, TE	1
Cavanni, P; Ferraguti, F; Mugnaini, M; Pinnola, V; Trist, D; Van Amsterdam, FT	1
Burnett, JP; Kingston, AE; Lodge, D; Mayne, NG	1
Dalby, NO; Thomsen, C	1
Orlando, LR; Penney, JB; Standaert, DG; Young, AB	1
Coderre, TJ; Fisher, K	1
Amos, BJ; Chesler, M	1
Keele, NB; Neugebauer, V; Shinnick-Gallagher, P	1
Adam, G; Cartmell, J; Chaboz, S; Henningsen, R; Kemp, JA; Klingelschmidt, A; Metzler, V; Monsma, F; Mutel, V; Schaffhauser, H; Wichmann, J	1
Adam, G; Bleuel, Z; Chaboz, S; Ellis, GJ; Faull, RL; Malherbe, P; Messer, J; Metzler, V; Mutel, V; Nilly, A; Richards, JG; Roughley, BS; Schlaeger, EJ	1
Bischoff, F; Janssen, C; Langlois, X; Lavreysen, H; Lesage, AS; Leysen, JE	1
Johnson, MP; Kingston, AE; Schkeryantz, JM	1

Reviews

2 review(s) available for alpha-methyl-4-carboxyphenylglycine and 4-carboxy-3-hydroxyphenylglycine

Article	Year
Ligands for glutamate receptors: design and therapeutic prospects. Journal of medicinal chemistry, 2000, Jul-13, Volume: 43, Issue:14 Topics: Animals; Drug Design; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Humans; Ligands; N-Methylaspartate; Receptors, AMPA; Receptors, Glutamate; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Synapses	2000
Prospects for metabotropic glutamate 1 receptor antagonists in the treatment of neuropathic pain. Journal of medicinal chemistry, 2007, May-31, Volume: 50, Issue:11 Topics: Analgesics; Animals; Humans; Pain; Peripheral Nervous System Diseases; Receptors, Metabotropic Glutamate	2007

Other Studies

15 other study(ies) available for alpha-methyl-4-carboxyphenylglycine and 4-carboxy-3-hydroxyphenylglycine

Article	Year
1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors. Journal of medicinal chemistry, 1995, Sep-15, Volume: 38, Issue:19 Topics: Animals; Cell Line; Cyclic AMP; Excitatory Amino Acid Antagonists; Glutamic Acid; Indans; Molecular Conformation; Molecular Structure; Phosphatidylinositols; Receptors, Metabotropic Glutamate; Type C Phospholipases	1995
Homology modeling of metabotropic glutamate receptors. (mGluRs) structural motifs affecting binding modes and pharmacological profile of mGluR1 agonists and competitive antagonists. Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20 Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Computer Simulation; Electrochemistry; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Conformation; Protein Structure, Secondary; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Sequence Homology	1996
Competitive antagonism by phenylglycine derivatives at type I metabotropic glutamate receptors. Molecular and cellular neurosciences, 1994, Volume: 5, Issue:3 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Aminobutyrates; Animals; Benzoates; Binding, Competitive; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cycloleucine; Cytidine Diphosphate Diglycerides; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Ibotenic Acid; Kainic Acid; Neurons; Neurotoxins; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Quisqualic Acid; Receptors, Metabotropic Glutamate; Recombinant Fusion Proteins; Signal Transduction	1994
Synaptic activation of metabotropic glutamate receptors in the parallel fibre-Purkinje cell pathway in rat cerebellar slices. Neuroscience, 1994, Volume: 63, Issue:4 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzoates; Cerebellum; Electric Stimulation; Glycine; In Vitro Techniques; Nerve Fibers; Neural Pathways; Purkinje Cells; Rats; Receptors, Metabotropic Glutamate; Synapses	1994
The function of metabotropic excitatory amino acid receptors in synaptic transmission in the thalamus: studies with novel phenylglycine antagonists. Neurochemistry international, 1994, Volume: 24, Issue:5 Topics: Action Potentials; Air; Animals; Benzoates; Cycloleucine; Glycine; Hot Temperature; Iontophoresis; Neurons; Nociceptors; Rats; Receptors, Metabotropic Glutamate; Synaptic Transmission; Thalamus	1994
Pharmacological analysis of carboxyphenylglycines at metabotropic glutamate receptors. European journal of pharmacology, 1994, Sep-15, Volume: 269, Issue:1 Topics: Adenylyl Cyclases; Animals; Benzoates; CHO Cells; Colforsin; Computer Simulation; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Glycine; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Kainic Acid; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Stereoisomerism	1994
Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes. Neuropharmacology, 1995, Volume: 34, Issue:8 Topics: Animals; Benzoates; Calcium; Cells, Cultured; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrolysis; Phosphatidylinositols; Quisqualic Acid; Rats; Receptors, Metabotropic Glutamate; Signal Transduction	1995
Modulation of seizure activity in mice by metabotropic glutamate receptor ligands. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:2 Topics: Animals; Anticonvulsants; Benzoates; Glycine; Male; Mice; Mice, Inbred DBA; Receptors, Metabotropic Glutamate; Seizures	1996
Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neuroscience letters, 1995, Dec-29, Volume: 202, Issue:1-2 Topics: Animals; Benzoates; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Male; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxins; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate	1995
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception. Pain, 1996, Volume: 68, Issue:2-3 Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Formaldehyde; Glycine; Male; Pain; Rats; Receptors, Metabotropic Glutamate; Resorcinols	1996
Characterization of an intracellular alkaline shift in rat astrocytes triggered by metabotropic glutamate receptors. Journal of neurophysiology, 1998, Volume: 79, Issue:2 Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloro-7-nitrobenzofurazan; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Animals; Animals, Newborn; Anti-Bacterial Agents; Astrocytes; Benzoates; Caffeine; Calcium; Cells, Cultured; Chlorides; Cycloleucine; Dicyclohexylcarbodiimide; Enzyme Inhibitors; Glycine; HEPES; Hydrogen-Ion Concentration; Indans; Intracellular Fluid; Ion Transport; Ionomycin; Ionophores; Macrolides; Nigericin; Rats; Receptors, Metabotropic Glutamate; Sodium	1998
Differential effects of metabotropic glutamate receptor antagonists on bursting activity in the amygdala. Journal of neurophysiology, 1999, Volume: 81, Issue:5 Topics: Amygdala; Animals; Benzoates; Cycloleucine; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Kindling, Neurologic; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Resorcinols; Synapses	1999
Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes. British journal of pharmacology, 1998, Volume: 123, Issue:3 Topics: Animals; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclopropanes; Glycine; Guanosine 5'-O-(3-Thiotriphosphate); Protein Binding; Rats; Receptors, Metabotropic Glutamate; Recombinant Proteins; Sulfur Radioisotopes; Transfection; Tritium	1998
Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections. Journal of neurochemistry, 2000, Volume: 75, Issue:6 Topics: Animals; Binding, Competitive; Brain; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Humans; Imidazoles; Indans; Intracellular Fluid; Kainic Acid; Male; Organ Specificity; Quinazolines; Quisqualic Acid; Rats; Rats, Inbred Strains; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Recombinant Proteins; Spinal Cord; Transfection	2000
[3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists. Molecular pharmacology, 2003, Volume: 63, Issue:5 Topics: Adamantane; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Brain; Cell Line; Cell Membrane; CHO Cells; Chromones; Cricetinae; Humans; Naphthalenes; Pyrans; Quinolines; Quinoxalines; Quisqualic Acid; Radioligand Assay; Rats; Receptors, Metabotropic Glutamate; Transfection; Tritium	2003