alpha-lapachone has been researched along with lapachol in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Müller, K; Sellmer, A; Wiegrebe, W | 1 |
| Campillo, M; Díaz-Peñate, RG; Estévez-Braun, A; García-Castellano, JM; Pardo, L; Pérez-Sacau, E; Ravelo, AG | 1 |
| Armstrong, V; Ciudad, K; Ferreira, J; Kemmerling, U; Maya, JD; Morello, A; Orellana, M; Salas, C; Tapia, RA | 1 |
| Andrade, CK; da Silva Júnior, EN; de Assis Lopes, F; de Castro, SL; de Simone, CA; de Souza, MC; Fernandes, MC; Ferreira, VF; Menna-Barreto, RF; Pinto, AV; Pinto, Mdo C | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Padrón, JM; Ríos-Luci, C | 1 |
| Bonifazi, EL; Burton, G; León, LG; Misico, RI; Montero, JC; Padrón, JM; Pandiella, A; Ríos-Luci, C | 1 |
| Caira, MR; da Silva Júnior, EN; Davies-Coleman, MT; de la Mare, JA; Edkins, AL; Hendricks, DT; Osoniyi, O; Pinto, AV; Shunmoogam-Gounden, N; Sunassee, SN; Veale, CG | 1 |
| Camara, CA; da Silva, EN; de Melo, IM; de Oliveira, RN; Diogo, EB; do Monte-Neto, RL; Ferreira, VF; Frézard, F; Guimarães, TT; Lanza, JS; Melo, MN; Pinto, Mdo C; Valença, WO | 1 |
| Clamor, C; Löcken, H; Müller, K | 1 |
| Calil, FA; Castilho, MS; Chiappetta, ERC; David, JS; Emery, FS; Fumagalli, F; Leite, FHA; Mello, RB; Nonato, MC | 1 |
| Ihara, M; Iida, A; Nagai, S; Sagara, M; Saito, K; Tahara, T; Watanabe, A; Yamano, Y; Yamashita, M; Yutani, M | 1 |
| Beteck, RM; Legoabe, LJ; Patel, OPS | 1 |
| Bacelar, TS; Buarque, CD; Castro, CP; Costa, PR; da Silva, AJ; Fernandes, RF; Maia, RC; Netto, CD; Rumjanek, VM; Salustiano, EJ | 1 |
| Green, IR; Hussain, H | 1 |
2 review(s) available for alpha-lapachone and lapachol
| Article | Year |
|---|---|
Antimalarial application of quinones: A recent update.
Topics: Antimalarials; Dose-Response Relationship, Drug; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinones; Structure-Activity Relationship | 2021 |
Lapachol and lapachone analogs: a journey of two decades of patent research(1997-2016).
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Design; Humans; Naphthoquinones; Neoplasms; Patents as Topic; Tabebuia | 2017 |
12 other study(ies) available for alpha-lapachone and lapachol
| Article | Year |
|---|---|
Potential antipsoriatic agents: lapacho compounds as potent inhibitors of HaCaT cell growth.
Topics: Administration, Topical; Anthralin; Anti-Inflammatory Agents; Cell Division; Cell Line; Humans; Keratinocytes; Keratolytic Agents; L-Lactate Dehydrogenase; Naphthoquinones; Psoriasis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1999 |
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line.
Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Furans; HL-60 Cells; Humans; Models, Molecular; Naphthoquinones; Phenanthrenes; Pyrans; Structure-Activity Relationship | 2007 |
Trypanosoma cruzi: activities of lapachol and alpha- and beta-lapachone derivatives against epimastigote and trypomastigote forms.
Topics: Animals; Molecular Structure; Naphthoquinones; Oxidation-Reduction; Stereoisomerism; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones.
Topics: Animals; Antiprotozoal Agents; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Naphthoquinones; Parasitic Sensitivity Tests; Stereoisomerism; Trypanosoma cruzi | 2008 |
Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Lipids; Magnetic Resonance Spectroscopy; Naphthoquinones; Prenylation; Structure-Activity Relationship | 2010 |
β-Lapachone analogs with enhanced antiproliferative activity.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases; Humans; Naphthoquinones; Reactive Oxygen Species; Topoisomerase Inhibitors | 2012 |
Cytotoxicity of lapachol, β-lapachone and related synthetic 1,4-naphthoquinones against oesophageal cancer cells.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Esophageal Neoplasms; Humans; Mice; Models, Molecular; Molecular Structure; Naphthoquinones; NIH 3T3 Cells; Structure-Activity Relationship | 2013 |
Potent naphthoquinones against antimony-sensitive and -resistant Leishmania parasites: synthesis of novel α- and nor-α-lapachone-based 1,2,3-triazoles by copper-catalyzed azide-alkyne cycloaddition.
Topics: Alkynes; Animals; Antimony; Antiprotozoal Agents; Azides; Catalysis; Cell Survival; Cells, Cultured; Copper; Cycloaddition Reaction; Drug Resistance; Leishmania; Leishmania infantum; Macrophages, Peritoneal; Mice; Naphthoquinones; Parasitic Sensitivity Tests; Species Specificity; Triazoles | 2013 |
Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.
Topics: Antineoplastic Agents; Apoptosis; Benzofurans; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Phosphorylation; Reactive Oxygen Species; STAT3 Transcription Factor | 2018 |
Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase.
Topics: Animals; Anthelmintics; Dihydroorotate Dehydrogenase; Drug Design; Humans; Ligands; Oxidoreductases Acting on CH-CH Group Donors; Quinones; Schistosoma mansoni; Schistosomiasis mansoni; Structure-Activity Relationship | 2019 |
STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae.
Topics: Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Molecular Structure; Naphthoquinones; STAT3 Transcription Factor; Structure-Activity Relationship; Tabebuia | 2020 |
Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells.
Topics: Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Leukemia; Leukocytes, Mononuclear; Mitomycin; Naphthoquinones | 2010 |