alpha-ketoisovalerate and 2-keto-4-methylvalerate

alpha-ketoisovalerate has been researched along with 2-keto-4-methylvalerate in 97 studies

Research

Studies (97)

Timeframe	Studies, this research(%)	All Research%
pre-1990	49 (50.52)	18.7374
1990's	19 (19.59)	18.2507
2000's	18 (18.56)	29.6817
2010's	10 (10.31)	24.3611
2020's	1 (1.03)	2.80

Authors

Authors	Studies
Bröer, A; Bröer, S; Deitmer, JW; Hamprecht, B; Rahman, B; Schneider, HP	1
Bröer, A; Bröer, S; Deitmer, JW; Halestrap, AP; Schneider, HP; Stegen, C	1
Halestrap, AP; Manning Fox, JE; Meredith, D	1
Grieben, K; Kramer, P; Langenbeck, U; Matthaei, D; Mench-Hoinowski, A; Schauder, P; Scheler, F	1
Cox, RP; Dancis, J; Sullivan, SG	1
Sterniczuk, A; Wałajtys-Rode, EI; Wojtczak, AB	1
Brosnan, JT; Brosnan, ME; Letto, J	1
Shiota, T; Swain, LM; Walser, M	1
Beck, K; Schadewaldt, P; Wendel, U	1
Kind, KL; Owens, JA; Robinson, JS; Smeaton, TC	1
Lenzen, S; Panten, U; Schmidt, W	1
Goodwin, GW; Harris, RA; Paxton, R; Powell, SM	1
Chuang, DT	1
Baker, DH; Funk, MA; Lowry, KR	1
Blinder, L; Frick, GP; Goodman, HM	1
Beck, K; Radeck, W; Staib, W	1
Herbertz, L; Langer, K; Schauder, P	1
Herbertz, L; Langer, K; Schauder, P; Zavelberg, D	1
Bieber, LL; DiLisa, F; Lilly, K; Lysiak, W; Toth, PP	1
Kolsaker, P; Nesbakken, T; Ormerod, J	1
Manning, CD; Matschinsky, FM; Meglasson, MD; Najafi, H	1
Hutson, SM	1
Goodwin, GW; Han, AC; Harris, RA; Paxton, R	1
Alexander, V; Swain, LM; Walser, M	1
Broyer, M; Dodu, C; Kamoun, PP; Kleinknecht, C; Laouari, D; Rocchiccioli, F	1
Demigné, C; Fafournoux, P; Rémésy, C	1
Bode, JC	1
Hutson, SM; Rannels, SL	1
Schauder, P	1
Henning, HV; Langenbeck, U; Matthaei, D; Schauder, P; Schröder, K	1
Chantler, C; Dalton, RN	2
Block, KP; Harper, AE; Miller, RH	1
Schepens, JT; Veerkamp, JH; Veldhuizen, JA; Wagenmakers, AJ	1
Veerkamp, JH; Wagenmakers, AJ	2
Goldstein, F; Norton, PM; Sansaricq, C; Snyderman, SE	1
Schepens, JT; Veerkamp, JH; Wagenmakers, AJ	1
Harper, AE; Miller, RH	1
Hashizume, I; Hayashi, T; Takagi, N; Tatsumi, M; Tokunaga, T; Tsuchiya, H	1
Frost, SC; Wells, MA	1
Corkey, BE; Martin-Requero, A; Walajtys-Rode, E; Williams, RJ; Williamson, JR	1
Bässler, KH; Pietrek, A	1
Sano, K; Shin, M; Umezawa, C; Yamada, O	1
Cremer, JE	1
Henning, HV; Langenbeck, U; Matthaei, D; Schauder, P; Scheler, F	1
Baker, DH; Boebel, KP	1
Harper, AE; Hutson, SM	1
Brand, K	1
McCully, V; Roberts, CM; Sokatch, JR	1
Brand, K; Hauschildt, S; Lüthje, J	1
Olson, MS; Patel, TB; Waymack, PP	1
Bier, DM; Karl, IE; Schwarz, HP	1
Cordewener, JH; van Hinsbergh, VW; Veerkamp, JH	1
Ckless, K; Schlottfeldt, JL; Wajner, M; Wannmacher, CM	1
Massad, G; Mobley, HL; Zhao, H	1
Encke, J; Fuchs, M; Gerlach, J; Neuhaus, P; Nündel, M; Riedel, E; Smith, M; Unger, J	1
Dawes, IW; Dickinson, JR; Sinclair, DA	1
Deferrari, G; Fiorini, F; Garibotto, G; Paoletti, E; Robaudo, C; Russo, R; Tizianello, A	1
Hoffer, LJ; Mamer, OA; Reimer, ML; Robitaille, L; Taveroff, A	1
Matsuo, Y; Walser, M; Yagi, M	1
Adelmeyer, F; Schadewaldt, P	1
Beer, W; Kingsley, R; Rabsch, W; Reissbrodt, R; Roberts, M; Williams, PH	1
Hamadeh, MJ; Hoffer, LJ; Mamer, OA; Robitaille, L; Taveroff, A	1
Biavati, B; Mattarelli, P	1
Hammen, HW; Ott, AC; Schadewaldt, P; Wendel, U	1
Claiborne, A; Snoep, JL; van Der Merwe, MJ; van Der Weijden, CC; Ward, DE; Westerhoff, HV	1
Farage, M; Reis, M; Wolosker, H	1
Dickel, C; Grimmsmann, T; Herrmann, C; Rustenbeck, I	1
Dutra-Filho, CS; Santos, CE; Souza, DO; Tasca, CI; Tavares, RG; Wajner, M	1
Coitinho, AS; de Bastiani, J; de Mello, CF; Fighera, MR; Lima, TT; Wajner, M	1
de Freitas Miranda, R; de Lima Pelaez, P; Funchal, C; Oliveira Loureiro, S; Pessoa-Pureur, R; Vivian, L; Wajner, M	1
Blanchard, JS; Sugantino, M; Yu, M; Zheng, R	1
Hu, P; Jiang, J; Li, X; Yang, H; Zheng, F	1
CAPURSO, L; LUZIETTI, L; PICCARDO, MG	1
Dutra-Filho, CS; Ribeiro, CA; Rosa, RB; Schuck, PF; Sgaravatti, AM; Wajner, M; Wannmacher, CM; Wyse, AT	1
Brinco, F; de Boer, MA; de Castro Vasques, V; Diligenti, F; Mallmann, F; Mello, CF; Wajner, M	1
Beck, HC; Hansen, AM; Lauritsen, FR	1
De Almeida, LM; Funchal, C; Gottfried, C; Pessoa-Pureur, R; Wajner, M	1
Matsuo, M; Murakami, T; Shimizu, A; Shimomura, Y	1
Braun, CA; Bridi, R; Dutra-Filho, CS; Lissi, EG; Wajner, M; Wannmacher, CM; Zorzi, GK	1
Babraj, JA; Crameri, RM; Døssing, S; Flyvbjerg, A; Hansen, M; Kjaer, M; Langberg, H; Miller, BF; Olesen, JL; Rennie, MJ; Smith, K; Welling, RJ	1
Dos Santos, AQ; Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Wajner, M; Zamoner, A	1
Eggeling, L; Kennerknecht, N; Marienhagen, J; Sahm, H	1
Funchal, C; Gottfried, C; Jacques-Silva, MC; Pessoa-Pureur, R; Santos, AQ; Schuck, PF; Wajner, M	1
Bürger, C; de Souza Wyse, AT; Dutra-Filho, CS; Wajner, A; Wajner, M; Wannmacher, CM	1
Duvekot, JJ; Minderman, G; Schierbeek, H; Schoonderwaldt, EM; Steegers, EA; van den Akker, CH; van Goudoever, JB; Vermes, A	1
Ghaly, H; Hamada, A; Panten, U; Rustenbeck, I; Schumacher, K; Willenborg, M	1
Bückle-Vallant, V; Eikmanns, BJ; Krause, FS; Messerschmidt, S	1
Huang, X; Huang, Z; Jin, C; Pan, Z; Wang, L; Zhong, Y	1
Chen, X; Guo, Y; He, M; Liang, C; Xiao, S; Xu, J; Yang, L; Yuan, Z; Zhang, Y	1
Fukuwatari, T; Nakata, C; Shibata, K	1
Chen, J; Du, G; Li, J; Liu, L; Shin, HD; Song, Y	1
Akiyama, M; Fukai, K; Harada, S; Hirayama, A; Iida, M; Kurihara, A; Kuwabara, K; Nishiwaki, Y; Oguma, Y; Okamura, T; Soga, T; Sugimoto, M; Sugiyama, D; Suzuki, A; Suzuki, C; Takebayashi, T; Takeuchi, A; Tomita, M	1
Grayson, I; Hall, C	1
Du, G; Liu, L; Nshimiyimana, P	1
Chiang, YR; Gicana, RG; Huang, CC; Huang, E; Wang, PH; Yan, JS; Yeh, FI	1

Reviews

4 review(s) available for alpha-ketoisovalerate and 2-keto-4-methylvalerate

Article	Year
Branched-chain amino acid metabolism. Annual review of nutrition, 1984, Volume: 4 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Chemical Phenomena; Chemistry, Physical; Cytosol; Dietary Proteins; Enzyme Activation; Hemiterpenes; Hormones; Humans; Isoenzymes; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Liver; Mitochondria; Multienzyme Complexes; Nitrogen; Oxidation-Reduction; Substrate Specificity; Tissue Distribution; Transaminases; Valine	1984
Nutrients for the brain: problems in supply. Early human development, 1981, Volume: 5, Issue:2 Topics: 3-Hydroxybutyric Acid; Age Factors; Animals; Biological Transport; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Energy Metabolism; Fetus; Hemiterpenes; Humans; Hydroxybutyrates; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Keto Acids; Ketone Bodies; Lactates; Rabbits; Rats	1981
Biotechnological production of alpha-keto acids: Current status and perspectives. Bioresource technology, 2016, Volume: 219 Topics: Biotechnology; Corynebacterium glutamicum; Gluconates; Hemiterpenes; Keto Acids; Ketoglutaric Acids; Metabolic Engineering; Pyruvic Acid; Saccharomyces cerevisiae	2016
Engineering of L-amino acid deaminases for the production of α-keto acids from L-amino acids. Bioengineered, 2019, Volume: 10, Issue:1 Topics: Amidohydrolases; Amino Acids; Ammonia-Lyases; Bacillus subtilis; Biocatalysis; Directed Molecular Evolution; Escherichia coli; Hemiterpenes; Humans; Industrial Microbiology; Keto Acids; Ketoglutaric Acids; Methionine; Protein Engineering; Proteus; Pyruvic Acid	2019

Trials

1 trial(s) available for alpha-ketoisovalerate and 2-keto-4-methylvalerate

Article	Year
Metabolism of orally administered branched-chain alpha-keto acids. Kidney international. Supplement, 1983, Volume: 15 Topics: Administration, Oral; Adult; Amino Acids, Branched-Chain; Amino Acids, Essential; Blood Glucose; Calcium; Cysteine; Female; Hemiterpenes; Humans; Insulin; Keto Acids; Male; Random Allocation; Time Factors; Tyrosine	1983

Other Studies

92 other study(ies) available for alpha-ketoisovalerate and 2-keto-4-methylvalerate

Article	Year
Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. The Biochemical journal, 1998, Jul-01, Volume: 333 ( Pt 1) Topics: Animals; Biological Transport; Carrier Proteins; Cytosol; Female; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Membrane Potentials; Microelectrodes; Monocarboxylic Acid Transporters; Oocytes; Patch-Clamp Techniques; Xenopus laevis	1998
Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. The Biochemical journal, 1999, Aug-01, Volume: 341 ( Pt 3) Topics: Animals; Base Sequence; Carrier Proteins; Cloning, Molecular; DNA Primers; Female; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Oocytes; Rats; Substrate Specificity; Xenopus laevis	1999
Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. The Journal of physiology, 2000, Dec-01, Volume: 529 Pt 2 Topics: Animals; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Muscle, Skeletal; Oocytes; Protein Isoforms; Substrate Specificity; Xenopus	2000
Plasma keto-analogues in uraemic patients. Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1979, Volume: 16 Topics: Amino Acids; Creatinine; Hemiterpenes; Humans; Keto Acids; Kidney Failure, Chronic; Renal Dialysis; Urea; Uremia	1979
Transient and long-term differential modulations of branched-chain alpha-keto acid decarboxylase activity in hypophysectomized rats. Biochimica et biophysica acta, 1978, Mar-01, Volume: 539, Issue:2 Topics: Animals; Caproates; Carboxy-Lyases; Hemiterpenes; Hypophysectomy; Keto Acids; Ketoglutaric Acids; Mitochondria, Liver; Pentanoic Acids; Rats	1978
Decarboxylation of branched-chain alpha-ketoacids in hepatocytes from alloxan-diabetic rats. The effect of insulin. Cell biochemistry and function, 1991, Volume: 9, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Decarboxylation; Diabetes Mellitus, Experimental; Hemiterpenes; Insulin; Keto Acids; Ketone Oxidoreductases; Ketones; Liver; Male; Multienzyme Complexes; Rats; Rats, Inbred Strains; Starvation	1991
Oxidation of 2-oxoisocaproate and 2-oxoisovalerate by the perfused rat heart. Interactions with fatty acid oxidation. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, Volume: 68, Issue:1 Topics: Animals; Caproates; Carbon Dioxide; Fatty Acids; Hemiterpenes; Keto Acids; Male; Myocardium; Oleic Acids; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains; Valerates	1990
Utilization for protein synthesis of leucine and valine compared with their keto analogues. The American journal of clinical nutrition, 1990, Volume: 51, Issue:3 Topics: Animals; Brain; Dose-Response Relationship, Drug; Hemiterpenes; Intracellular Membranes; Keto Acids; Leucine; Liver; Male; Myocardium; Nutritional Requirements; Oxidation-Reduction; Protein Biosynthesis; Rats; Rats, Inbred Strains; Salivary Glands; Valine	1990
Analysis of maple syrup urine disease in cell culture: use of substrates. Clinica chimica acta; international journal of clinical chemistry, 1989, Sep-15, Volume: 184, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Cells, Cultured; Fibroblasts; Hemiterpenes; Humans; Isoleucine; Keto Acids; Ketone Oxidoreductases; Leucine; Maple Syrup Urine Disease; Multienzyme Complexes; Substrate Specificity; Valine	1989
The placenta releases branched-chain keto acids into the umbilical and uterine circulations in the pregnant sheep. Journal of developmental physiology, 1989, Volume: 12, Issue:2 Topics: Animals; Blood Circulation; Female; Fetal Blood; Fetus; Hemiterpenes; Keto Acids; Maternal-Fetal Exchange; Placenta; Pregnancy; Sheep; Uterus	1989
Transamination of neutral amino acids and 2-keto acids in pancreatic B-cell mitochondria. The Journal of biological chemistry, 1985, Oct-15, Volume: 260, Issue:23 Topics: Animals; Caproates; Cytoplasm; Glutamates; Glutamic Acid; Glutamine; Hemiterpenes; Islets of Langerhans; Keto Acids; Kinetics; Leucine; Mice; Mice, Obese; Mitochondria; Transaminases; Valine	1985
Regulation of the branched-chain 2-oxo acid dehydrogenase complex in hepatocytes isolated from rats fed on a low-protein diet. The Biochemical journal, 1986, Mar-01, Volume: 234, Issue:2 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Bucladesine; Caproates; Dichloroacetic Acid; Dietary Proteins; Hemiterpenes; Hydrocarbons, Chlorinated; In Vitro Techniques; Keto Acids; Ketone Oxidoreductases; Liver; Male; Multienzyme Complexes; Rats; Rats, Inbred Strains	1986
Assays for E1 and E2 components of the branched-chain keto acid dehydrogenase complex. Methods in enzymology, 1988, Volume: 166 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Caproates; Carbon Radioisotopes; Cattle; Chromatography, Ion Exchange; Hemiterpenes; Indicators and Reagents; Keto Acids; Ketone Oxidoreductases; Kinetics; Liver; Multienzyme Complexes; Radioisotope Dilution Technique; Substrate Specificity; Valerates	1988
Utilization of the L- and DL-isomers of alpha-keto-beta-methylvaleric acid by rats and comparative efficacy of the keto analogs of branched-chain amino acids provided as ornithine, lysine and histidine salts. The Journal of nutrition, 1987, Volume: 117, Issue:9 Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Eating; Hemiterpenes; Histidine; Isoleucine; Keto Acids; Leucine; Lysine; Male; Ornithine; Rats; Rats, Inbred Strains; Salts; Stereoisomerism; Valine	1987
Transamination and oxidation of leucine and valine in rat adipose tissue. The Journal of biological chemistry, 1988, Mar-05, Volume: 263, Issue:7 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adipose Tissue; Animals; Carbon Dioxide; Enzyme Activation; Glucose; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Leucine; Male; Multienzyme Complexes; Oxidation-Reduction; Rats; Transaminases; Valine	1988
Simple method for rapid quantification of branched-chain 2-oxo acids in physiological fluids as quinoxalinol derivatives by high-performance liquid chromatography. Journal of chromatography, 1988, Nov-18, Volume: 432 Topics: Amino Acids, Branched-Chain; Chromatography, High Pressure Liquid; Diet; Hemiterpenes; Humans; Keto Acids; Maple Syrup Urine Disease; Quinoxalines	1988
[Plasma level of branched-chain amino and keto acids in healthy subjects after an intravenous dose of MCT/LCT or LCT]. Beitrage zu Infusionstherapie und klinische Ernahrung, 1988, Volume: 20 Topics: Adult; Amino Acids, Branched-Chain; Caproates; Fasting; Fat Emulsions, Intravenous; Female; Hemiterpenes; Humans; Infusions, Intravenous; Insulin; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Random Allocation; Triglycerides; Valerates; Valine	1988
Sex-specific differences in plasma branched-chain keto acid levels in obesity. The American journal of clinical nutrition, 1987, Volume: 46, Issue:1 Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine	1987
Quantitation of the effect of L-carnitine on the levels of acid-soluble short-chain acyl-CoA and CoASH in rat heart and liver mitochondria. The Journal of biological chemistry, 1988, Jan-25, Volume: 263, Issue:3 Topics: Acyl Coenzyme A; Animals; Caprylates; Carnitine; Coenzyme A; Hemiterpenes; Keto Acids; Male; Mitochondria, Heart; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1988
Mechanism of biosynthesis of 2-oxo-3-methylvalerate in Chlorobium vibrioforme. Journal of bacteriology, 1988, Volume: 170, Issue:7 Topics: Acetyl Coenzyme A; Bacteria; Chemical Phenomena; Chemistry; Hemiterpenes; Keto Acids; Magnetic Resonance Spectroscopy	1988
Fuel-stimulated insulin secretion by clonal hamster beta-cell line HIT T-15. Diabetes, 1987, Volume: 36, Issue:4 Topics: 3-O-Methylglucose; Animals; Cell Line; Cricetinae; Dihydroxyacetone; Energy Metabolism; Glucose; Glutamine; Hemiterpenes; Insulin; Insulin Secretion; Islets of Langerhans; Keto Acids; Lactates; Lactic Acid; Methylglucosides	1987
pH regulation of mitochondrial branch chain alpha-keto acid transport and oxidation in rat heart mitochondria. The Journal of biological chemistry, 1987, Jul-15, Volume: 262, Issue:20 Topics: Animals; Biological Transport; Caproates; Hemiterpenes; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Male; Mitochondria, Heart; Rats; Rats, Inbred Strains; Valerates; Valinomycin	1987
Activation of branched-chain alpha-ketoacid dehydrogenase in isolated hepatocytes by branched-chain alpha-ketoacids. Archives of biochemistry and biophysics, 1987, Volume: 258, Issue:1 Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Caproates; Enzyme Activation; Hemiterpenes; Hydrocarbons, Chlorinated; Hydroxybutyrates; Keto Acids; Ketone Oxidoreductases; Liver; Multienzyme Complexes; Rats; Sodium Fluoride	1987
Measurement of branched-chain ketoacids in plasma by high-performance liquid chromatography. Analytical biochemistry, 1987, Aug-01, Volume: 164, Issue:2 Topics: Animals; Chromatography, High Pressure Liquid; Female; Hemiterpenes; Humans; Keto Acids; Male; Rats; Rats, Inbred Strains; Reference Values	1987
Efficiency of substitution of 2-ketoisocaproic acid and 2-ketoisovaleric acid in the diet of normal and uremic growing rats. The American journal of clinical nutrition, 1986, Volume: 44, Issue:6 Topics: Animals; Diet; Growth; Hemiterpenes; Keto Acids; Leucine; Male; Nitrogen; Nutritive Value; Rats; Rats, Inbred Strains; Urea; Uremia; Valine	1986
Respective contribution of plasma branched-chain amino acids and 2-keto acids to the hepatic metabolism of the carbon moiety of branched-chain amino acids in fed rats. The Journal of nutrition, 1986, Volume: 116, Issue:11 Topics: Amino Acids, Branched-Chain; Animals; Caseins; Dietary Proteins; Hemiterpenes; Hepatic Veins; Keto Acids; Liver; Male; Portal Vein; Rats; Rats, Inbred Strains	1986
[Branched-chain amino acids and their ketoanalogs: therapeutic uses in patients with chronic liver or kidney failure]. Der Internist, 1985, Volume: 26, Issue:7 Topics: Administration, Oral; Amino Acids; Amino Acids, Branched-Chain; Amino Acids, Essential; Blood-Brain Barrier; Dietary Proteins; Hemiterpenes; Hepatic Encephalopathy; Humans; Keto Acids; Kidney Failure, Chronic; Liver Cirrhosis; Renal Dialysis	1985
Characterization of a mitochondrial transport system for branched chain alpha-keto acids. The Journal of biological chemistry, 1985, Nov-15, Volume: 260, Issue:26 Topics: Animals; Biological Transport; Carboxylic Acids; Carrier Proteins; Coumaric Acids; Hemiterpenes; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Male; Mitochondria, Heart; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains	1985
Pharmacokinetic and metabolic interrelationships among branched-chain keto and amino acids in humans. The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:6 Topics: Adult; Amino Acids, Branched-Chain; Drug Interactions; Female; Half-Life; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kinetics; Leucine; Male; Reference Values; Time Factors; Valine	1985
Influence of insulin on blood levels of branched chain keto and amino acids in man. Metabolism: clinical and experimental, 1983, Volume: 32, Issue:4 Topics: Adult; Amino Acids, Branched-Chain; Blood Glucose; Female; Hemiterpenes; Hormones; Humans; Insulin; Isoleucine; Keto Acids; Leucine; Male; Valine	1983
The activity state of the branched-chain 2-oxo acid dehydrogenase complex in rat tissues. The Biochemical journal, 1984, May-15, Volume: 220, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Diphosphate; Animals; Carbon Dioxide; Hemiterpenes; In Vitro Techniques; Keto Acids; Ketone Oxidoreductases; Magnesium; Male; Methods; Multienzyme Complexes; Muscles; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution	1984
Interaction of octanoate with branched-chain 2-oxo acid oxidation in rat and human muscle in vitro. The International journal of biochemistry, 1984, Volume: 16, Issue:9 Topics: Acyl Coenzyme A; Amino Acids, Branched-Chain; Animals; Caprylates; Food Deprivation; Hemiterpenes; Humans; Keto Acids; Male; Muscles; Oxidation-Reduction; Rats	1984
The relationship between the branched chain amino acids and their alpha-ketoacids in maple syrup urine disease. Pediatric research, 1984, Volume: 18, Issue:9 Topics: Amino Acids, Branched-Chain; Caproates; Child; Child, Preschool; Female; Hemiterpenes; Humans; Infant; Infant, Newborn; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Valerates; Valine	1984
Effect of starvation and exercise on actual and total activity of the branched-chain 2-oxo acid dehydrogenase complex in rat tissues. The Biochemical journal, 1984, Nov-01, Volume: 223, Issue:3 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Citrate (si)-Synthase; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Leucine; Male; Multienzyme Complexes; Muscles; Organ Size; Physical Exertion; Rats; Rats, Inbred Strains; Starvation; Tissue Distribution	1984
Metabolism of valine and 3-methyl-2-oxobutanoate by the isolated perfused rat kidney. The Biochemical journal, 1984, Nov-15, Volume: 224, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Hemiterpenes; In Vitro Techniques; Isoleucine; Keto Acids; Ketone Oxidoreductases; Kidney; Leucine; Male; Multienzyme Complexes; Oxidation-Reduction; Perfusion; Rats; Valine	1984
High-performance liquid chromatography of alpha-keto acids in human saliva. Archives of oral biology, 1983, Volume: 28, Issue:11 Topics: Adult; Chromatography, High Pressure Liquid; Hemiterpenes; Humans; Keto Acids; Ketoglutaric Acids; Pyruvates; Pyruvic Acid; Saliva	1983
The relationship between branched-chain amino acids and alpha-keto acids in blood in uremia. Kidney international. Supplement, 1983, Volume: 16 Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Female; Glutamates; Hemiterpenes; Humans; Intracellular Fluid; Keto Acids; Male; Pyruvates; Renal Dialysis; Uremia	1983
Metabolism of branched-chain keto acids in neonatal rat liver perfusions. Archives of biochemistry and biophysics, 1983, Oct-15, Volume: 226, Issue:2 Topics: Animals; Animals, Newborn; Decanoic Acids; Hemiterpenes; Keto Acids; Kinetics; Leucine; Liver; Oxidation-Reduction; Perfusion; Rats; Rats, Inbred Strains; Valine	1983
The effect of starvation on branched-chain 2-oxo acid oxidation in rat muscle. The Biochemical journal, 1984, Apr-01, Volume: 219, Issue:1 Topics: Amino Acids, Branched-Chain; Aminooxyacetic Acid; Animals; Hemiterpenes; Keto Acids; Leucine; Male; Muscle Proteins; Muscles; Myocardium; Oxidation-Reduction; Rats; Rats, Inbred Strains; Starvation	1984
Regulation of the branched chain alpha-ketoacid pathway in liver. The Journal of biological chemistry, 1982, Aug-25, Volume: 257, Issue:16 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetoacetates; Acetyl Coenzyme A; Acyl Coenzyme A; Animals; Carbon Dioxide; Citric Acid Cycle; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Liver; Male; Multienzyme Complexes; Oleic Acid; Oleic Acids; Propionates; Rats; Rats, Inbred Strains	1982
Enzymatic and pharmacokinetic studies on the metabolism of branched chain alpha-keto acids in the rat. Zeitschrift fur Ernahrungswissenschaft, 1983, Volume: 22, Issue:1 Topics: Animals; Brain; Cell-Free System; Hemiterpenes; Keto Acids; Kidney; Kinetics; Male; Mitochondria; Mitochondria, Liver; Mitochondria, Muscle; Oxidoreductases; Rats; Rats, Inbred Strains; Transaminases	1983
Effect of dietary excess leucine on the levels of branched chain alpha-keto acids and ketone bodies in blood and the liver of rats. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1983, Volume: 53, Issue:2 Topics: Animals; Body Weight; Diet; Hemiterpenes; Keto Acids; Ketone Bodies; Leucine; Liver; Male; NAD; Rats; Rats, Inbred Strains	1983
Blood levels of branched-chain alpha-keto acids in uremia: effect of an oral glucose tolerance test. Klinische Wochenschrift, 1981, Aug-03, Volume: 59, Issue:15 Topics: Adult; Blood Glucose; C-Peptide; Female; Glucose Tolerance Test; Hemiterpenes; Humans; Insulin; Keto Acids; Kidney Failure, Chronic; Male; Middle Aged; Uremia	1981
Comparative utilization of the alpha-keto and D- and L-alpha-hydroxy analogs of leucine, isoleucine and valine by chicks and rats. The Journal of nutrition, 1982, Volume: 112, Issue:10 Topics: Animals; Caproates; Chickens; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Pentanoic Acids; Rats; Species Specificity; Structure-Activity Relationship; Valerates; Valine	1982
Blood and tissue branched-chain amino and alpha-keto acid concentrations: effect of diet, starvation, and disease. The American journal of clinical nutrition, 1981, Volume: 34, Issue:2 Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Experimental; Diet; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Rats; Starvation; Valine	1981
Metabolism of 2-oxoacid analogues of leucine, valine and phenylalanine by heart muscle, brain and kidney of the rat. Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1 Topics: Aminooxyacetic Acid; Animals; Brain; Hemiterpenes; Keto Acids; Kidney; Myocardium; Phenylpyruvic Acids; Rats; Rats, Inbred Strains	1981
Purification of a branched-chain keto acid dehydrogenase from Pseudomonas putida. Journal of bacteriology, 1981, Volume: 148, Issue:2 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Caproates; Coenzyme A; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Multienzyme Complexes; NAD; Pentanoic Acids; Pseudomonas; Substrate Specificity; Valine	1981
Influence of dietary nitrogen intake on mammalian branched chain alpha-keto acid dehydrogenase activity. The Journal of nutrition, 1981, Volume: 111, Issue:12 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids; Animals; Caseins; Dietary Proteins; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Liver; Male; Multienzyme Complexes; Nitrogen; Rats; Rats, Inbred Strains	1981
The effect of the monocarboxylate translocator inhibitor, alpha-cyanocinnamate, on the oxidation of branched chain alpha-keto acids in rat liver. Archives of biochemistry and biophysics, 1980, Volume: 201, Issue:2 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Biological Transport; Carrier Proteins; Cinnamates; Hemiterpenes; Intracellular Membranes; Keto Acids; Ketone Oxidoreductases; Male; Mitochondria, Liver; Monocarboxylic Acid Transporters; Multienzyme Complexes; Nitriles; Rats	1980
The alpha-keto acids of branched-chain amino acids: simplified derivatization for physiological samples and complete separation as quinoxalinols by packed column gas chromatography. Analytical biochemistry, 1980, Nov-01, Volume: 108, Issue:2 Topics: Amino Acids, Branched-Chain; Animals; Chromatography, Gas; Hemiterpenes; Keto Acids; Muscles; Pyruvates; Quinoxalines; Rats	1980
Degradation of branched-chain amino acids and 2-oxo acids in human and rat muscle. Biochemical medicine, 1980, Volume: 24, Issue:2 Topics: Amino Acids, Branched-Chain; Animals; Carnitine; Hemiterpenes; Humans; Keto Acids; Leucine; Liver; Male; Mitochondria, Muscle; Muscles; Oxidation-Reduction; Rats; Valine	1980
Immunosuppressive effects of organic acids accumulating in patients with maple syrup urine disease. Journal of inherited metabolic disease, 1995, Volume: 18, Issue:2 Topics: Caproates; Cells, Cultured; Hemiterpenes; Humans; Keto Acids; Lymphocyte Activation; Maple Syrup Urine Disease; Mitogens; Pentanoic Acids; Phytohemagglutinins; Valerates	1995
Proteus mirabilis amino acid deaminase: cloning, nucleotide sequence, and characterization of aad. Journal of bacteriology, 1995, Volume: 177, Issue:20 Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Base Sequence; Biological Transport; Cloning, Molecular; Deamination; Ferric Compounds; Gene Dosage; Hemiterpenes; Humans; Keto Acids; Molecular Sequence Data; Mutagenesis, Insertional; Proteus Infections; Proteus mirabilis; Recombinant Proteins; Restriction Mapping; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Siderophores; Species Specificity	1995
Alpha-keto acid metabolism by hepatocytes cultured in a hybrid liver support bioreactor. The International journal of artificial organs, 1994, Volume: 17, Issue:10 Topics: Animals; Artificial Organs; Cells, Cultured; Cytochrome P-450 Enzyme System; Hemiterpenes; Keto Acids; Ketoglutaric Acids; Liver; Liver Function Tests; Perfusion; Potassium; Protein Biosynthesis; Pyruvates; Pyruvic Acid; Swine	1994
Purification and characterization of the branched chain alpha-ketoacid dehydrogenase complex from Saccharomyces cerevisiae. Biochemistry and molecular biology international, 1993, Volume: 31, Issue:5 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Kinetics; Molecular Weight; Multienzyme Complexes; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Substrate Specificity	1993
Peripheral metabolism of branched-chain keto acids in patients with chronic renal failure. Mineral and electrolyte metabolism, 1993, Volume: 19, Issue:1 Topics: Adult; Amino Acids, Branched-Chain; Bicarbonates; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Kidney Failure, Chronic; Leucine; Male; Middle Aged; Valine	1993
Alpha-keto and alpha-hydroxy branched-chain acid interrelationships in normal humans. The Journal of nutrition, 1993, Volume: 123, Issue:9 Topics: Adult; Amino Acids, Branched-Chain; Dietary Proteins; Evaluation Studies as Topic; Fasting; Female; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Mass Spectrometry; Oxidation-Reduction; Protein Binding; Time Factors; Valerates; Valine	1993
Arteriovenous differences and tissue concentrations of branched-chain ketoacids. The Journal of laboratory and clinical medicine, 1993, Volume: 121, Issue:6 Topics: Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Dogs; Hemiterpenes; Keto Acids; Kidney; Liver; Male; Muscles; Myocardium; Rats; Rats, Sprague-Dawley	1993
Coupled enzymatic assay for estimation of branched-chain L-amino acid aminotransferase activity with 2-Oxo acid substrates. Analytical biochemistry, 1996, Jun-15, Volume: 238, Issue:1 Topics: Animals; Cattle; Cell-Free System; Cells, Cultured; Endothelium, Vascular; Hemiterpenes; Isoenzymes; Keto Acids; Linear Models; Mitochondria, Heart; Rats; Substrate Specificity; Temperature; Transaminases	1996
Iron-regulated excretion of alpha-keto acids by Salmonella typhimurium. Journal of bacteriology, 1997, Volume: 179, Issue:14 Topics: 2,2'-Dipyridyl; Bacterial Proteins; Biological Transport; Conalbumin; Culture Media; Enterobactin; Hemiterpenes; Iron; Keto Acids; Ketoglutaric Acids; Membrane Proteins; Pyruvic Acid; Salmonella typhimurium	1997
Effects of leucine on whole body leucine, valine, and threonine metabolism in humans. The American journal of physiology, 1997, Volume: 272, Issue:6 Pt 1 Topics: Adult; Amino Acids; Biotransformation; Carbon Isotopes; Deuterium; Female; Hemiterpenes; Humans; Keto Acids; Kinetics; Leucine; Male; Radioisotope Dilution Technique; Threonine; Time Factors; Valine	1997
L-leucine auxotrophy in Bifidobacterium globosum. The new microbiologica, 1999, Volume: 22, Issue:1 Topics: 3-Isopropylmalate Dehydrogenase; Alcohol Oxidoreductases; Bifidobacterium; Culture Media; Hemiterpenes; Keto Acids; Leucine; Plasmids	1999
Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease. Journal of inherited metabolic disease, 1999, Volume: 22, Issue:6 Topics: Adolescent; Adult; Amino Acids, Branched-Chain; Child; Child, Preschool; Hemiterpenes; Humans; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Metabolic Clearance Rate; Middle Aged; Valine	1999
Branched-chain alpha-keto acid catabolism via the gene products of the bkd operon in Enterococcus faecalis: a new, secreted metabolite serving as a temporary redox sink. Journal of bacteriology, 2000, Volume: 182, Issue:11 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adenosine Triphosphate; Aerobiosis; Amino Acid Sequence; Anaerobiosis; Base Sequence; Enterococcus faecalis; Genes, Bacterial; Hemiterpenes; Keto Acids; Ketone Oxidoreductases; Models, Biological; Molecular Sequence Data; Multienzyme Complexes; Multigene Family; Operon; Oxidation-Reduction; Promoter Regions, Genetic; Pyruvates; Response Elements; Transcription, Genetic	2000
Chloride-dependent inhibition of vesicular glutamate uptake by alpha-keto acids accumulated in maple syrup urine disease. Biochimica et biophysica acta, 2000, Jul-03, Volume: 1475, Issue:2 Topics: Amino Acid Transport System X-AG; Animals; ATP-Binding Cassette Transporters; Biological Transport; Brain; Cell Membrane; Chlorides; Electrochemistry; Glutamic Acid; Hemiterpenes; Hydrogen-Ion Concentration; In Vitro Techniques; Keto Acids; Maple Syrup Urine Disease; Membrane Potentials; Rats; Synaptic Vesicles	2000
Mitochondria present in excised patches from pancreatic B-cells may form microcompartments with ATP-dependent potassium channels. Bioscience reports, 1999, Volume: 19, Issue:2 Topics: Adenosine Triphosphate; Aldehydes; Animals; Antimycin A; Ascorbic Acid; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Compartmentation; Cell Membrane; Enzyme Inhibitors; Fluorescent Dyes; Hemiterpenes; Islets of Langerhans; Keto Acids; Mice; Mitochondria; Oligomycins; Potassium Channels; Rhodamines; Rotenone; Sodium Azide; Succinic Acid; Tetramethylphenylenediamine; Tolbutamide	1999
Inhibition of glutamate uptake into synaptic vesicles of rat brain by the metabolites accumulating in maple syrup urine disease. Journal of the neurological sciences, 2000, Dec-01, Volume: 181, Issue:1-2 Topics: Animals; Brain; Glutamic Acid; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Male; Maple Syrup Urine Disease; Neurons; Rats; Rats, Wistar; Synaptic Vesicles; Synaptosomes; Valine	2000
Pharmacological evidence that alpha-ketoisovaleric acid induces convulsions through GABAergic and glutamatergic mechanisms in rats. Brain research, 2001, Mar-09, Volume: 894, Issue:1 Topics: Animals; Corpus Striatum; Excitatory Amino Acid Antagonists; GABA Agonists; Hemiterpenes; Keto Acids; Male; Maple Syrup Urine Disease; Rats; Rats, Wistar; Receptors, GABA; Receptors, N-Methyl-D-Aspartate; Seizures	2001
Effect of the branched-chain alpha-ketoacids accumulating in maple syrup urine disease on the high molecular weight neurofilament subunit (NF-H) in rat cerebral cortex. Metabolic brain disease, 2002, Volume: 17, Issue:2 Topics: Animals; Animals, Newborn; Cerebral Cortex; Cytoskeleton; Dose-Response Relationship, Drug; Hemiterpenes; Immunohistochemistry; Keto Acids; Maple Syrup Urine Disease; Nerve Degeneration; Neurofilament Proteins; Neurons; Rats; Rats, Wistar; Subcellular Fractions	2002
Mycobacterium tuberculosis ketopantoate hydroxymethyltransferase: tetrahydrofolate-independent hydroxymethyltransferase and enolization reactions with alpha-keto acids. Biochemistry, 2003, Jan-14, Volume: 42, Issue:1 Topics: Amino Acids; Bacterial Proteins; Catalysis; Deuterium; Enzyme Activation; Hemiterpenes; Hydrogen-Ion Concentration; Hydroxymethyl and Formyl Transferases; Keto Acids; Metals; Molecular Conformation; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Pantothenic Acid; Protons; Pyruvic Acid; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tetrahydrofolates	2003
[Plasma branched-chain ketoacids metabolism in patients with chronic renal failure after oral administration of ketosteril]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1999, Volume: 21, Issue:6 Topics: Administration, Oral; Adult; Amino Acids, Essential; Female; Hemiterpenes; Humans; Keto Acids; Kidney Failure, Chronic; Male; Middle Aged	1999
[VARIOUS ASPECTS OF KETOACIDURIA AND KETOACIDEMIA IN DIABETICS: URINARY EXCRETION AND HEMATIC LEVELS OF ALPHA-KETOISOCAPROIC ACID, ALPHA-KETOISOVALERIC ACID, PYRUVIC ACID AND ALPHA-KETOGLUTARIC ACID]. Il Policlinico. Sezione medica, 1963, Volume: 70 Topics: Biomedical Research; Blood Chemical Analysis; Diabetes Mellitus; Hemiterpenes; Humans; Keto Acids; Ketoglutaric Acids; Ketosis; Maple Syrup Urine Disease; Pyruvates; Pyruvic Acid; Urine	1963
Inhibition of brain energy metabolism by the alpha-keto acids accumulating in maple syrup urine disease. Biochimica et biophysica acta, 2003, Nov-20, Volume: 1639, Issue:3 Topics: Animals; Biological Transport; Brain; Carbon Dioxide; Disease Models, Animal; Energy Metabolism; Glucose; Hemiterpenes; Humans; Keto Acids; Lactates; Maple Syrup Urine Disease; Rats; Rats, Wistar; Succinate Cytochrome c Oxidoreductase	2003
Intrahippocampal administration of the alpha-keto acids accumulating in maple syrup urine disease provokes learning deficits in rats. Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:1 Topics: Animals; Avoidance Learning; Behavior, Animal; Hemiterpenes; Hippocampus; Injections, Intraventricular; Keto Acids; Male; Maple Syrup Urine Disease; Rats; Rats, Wistar; Reaction Time	2004
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. Journal of applied microbiology, 2004, Volume: 96, Issue:5 Topics: Cell Membrane; Chromatography; Culture Media; Fatty Acids; Flavoring Agents; Food Microbiology; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Meat Products; Oxidation-Reduction; Pentanoic Acids; Pyruvic Acid; Staphylococcus; Valine	2004
Evidence that the branched-chain alpha-keto acids accumulating in maple syrup urine disease induce morphological alterations and death in cultured astrocytes from rat cerebral cortex. Glia, 2004, Nov-15, Volume: 48, Issue:3 Topics: Actins; Animals; Animals, Newborn; Astrocytes; Brain; Cell Death; Cell Shape; Cells, Cultured; Cerebral Cortex; Creatine; Creatine Kinase; Cytoskeleton; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Hemiterpenes; Keto Acids; Lysophospholipids; Maple Syrup Urine Disease; Rats; Rats, Wistar; rhoA GTP-Binding Protein	2004
Dissociation of branched-chain alpha-keto acid dehydrogenase kinase (BDK) from branched-chain alpha-keto acid dehydrogenase complex (BCKDC) by BDK inhibitors. Journal of nutritional science and vitaminology, 2005, Volume: 51, Issue:1 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Caproates; Diet, Protein-Restricted; Hemiterpenes; Hydrocarbons, Chlorinated; Immunosorbent Techniques; Keto Acids; Liver; Protein Kinase Inhibitors; Protein Kinases; Rats	2005
alpha-keto acids accumulating in maple syrup urine disease stimulate lipid peroxidation and reduce antioxidant defences in cerebral cortex from young rats. Metabolic brain disease, 2005, Volume: 20, Issue:2 Topics: Animals; Antioxidants; Catalase; Cerebral Cortex; Disease Models, Animal; Free Radicals; Glutathione Peroxidase; Hemiterpenes; Keto Acids; Lipid Peroxidation; Male; Maple Syrup Urine Disease; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2005
Coordinated collagen and muscle protein synthesis in human patella tendon and quadriceps muscle after exercise. The Journal of physiology, 2005, Sep-15, Volume: 567, Issue:Pt 3 Topics: Adult; Carbon Radioisotopes; Collagen; Exercise; Hemiterpenes; Humans; Keto Acids; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Nitrogen Radioisotopes; Patella; Proline; Sarcoplasmic Reticulum; Tendons; Thigh; Valine	2005
Branched-chain alpha-keto acids accumulating in maple syrup urine disease induce reorganization of phosphorylated GFAP in C6-glioma cells. Metabolic brain disease, 2005, Volume: 20, Issue:3 Topics: Animals; Cell Line, Tumor; Cytoskeleton; Glial Fibrillary Acidic Protein; Glioma; Hemiterpenes; Keto Acids; Maple Syrup Urine Disease; Phosphorylation; Rats	2005
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum. Journal of bacteriology, 2005, Volume: 187, Issue:22 Topics: Alanine; Aspartic Acid; Bacterial Proteins; Butyrates; Carbon-Sulfur Lyases; Corynebacterium glutamicum; Gene Deletion; Glutamic Acid; Hemiterpenes; Keto Acids; Phenylpyruvic Acids; Pyruvic Acid; Substrate Specificity; Transaminases	2005
Creatine and antioxidant treatment prevent the inhibition of creatine kinase activity and the morphological alterations of C6 glioma cells induced by the branched-chain alpha-keto acids accumulating in maple syrup urine disease. Cellular and molecular neurobiology, 2006, Volume: 26, Issue:1 Topics: Animals; Antioxidants; Cell Line, Tumor; Cell Shape; Creatine; Creatine Kinase; Glioma; Hemiterpenes; Humans; Keto Acids; Maple Syrup Urine Disease; Rats	2006
Synaptic plasma membrane Na(+), K (+)-ATPase activity is significantly reduced by the alpha-keto acids accumulating in maple syrup urine disease in rat cerebral cortex. Metabolic brain disease, 2007, Volume: 22, Issue:1 Topics: Alanine; Animals; Cell Membrane; Cerebral Cortex; Enzyme Activation; Hemiterpenes; Keto Acids; Maple Syrup Urine Disease; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synapses	2007
Amino acid metabolism in the human fetus at term: leucine, valine, and methionine kinetics. Pediatric research, 2011, Volume: 70, Issue:6 Topics: Blood Flow Velocity; Carbon Isotopes; Female; Fetal Blood; Fetus; Hemiterpenes; Humans; Keto Acids; Kinetics; Leucine; Mass Spectrometry; Maternal-Fetal Exchange; Methionine; Nitrogen Isotopes; Pregnancy; Statistics, Nonparametric; Valine	2011
Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation. Metabolism: clinical and experimental, 2013, Volume: 62, Issue:10 Topics: Acetoacetates; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Citric Acid; Female; Flavin-Adenine Dinucleotide; Fluorescence; Glipizide; Glucose; Hemiterpenes; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Keto Acids; Mice; Mitochondria; NADP; Pyruvic Acid; Sulfonylurea Compounds	2013
Metabolic engineering of Corynebacterium glutamicum for 2-ketoisocaproate production. Applied microbiology and biotechnology, 2014, Volume: 98, Issue:1 Topics: Acetates; Corynebacterium glutamicum; Gene Deletion; Gene Expression; Glucose; Hemiterpenes; Keto Acids; Metabolic Engineering; Metabolic Networks and Pathways	2014
[Simultaneous determination of five active components of compound α-ketoacid tablet in human urine by ion-pair reversed-phase high performance liquid chromatography]. Se pu = Chinese journal of chromatography, 2015, Volume: 33, Issue:2 Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Hemiterpenes; Keto Acids; Limit of Detection; Methionine; Tablets	2015
Production of C4 and C5 branched-chain alcohols by engineered Escherichia. coli. Journal of industrial microbiology & biotechnology, 2015, Volume: 42, Issue:11 Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Alcohol Dehydrogenase; Alcohols; Butanols; Decarboxylation; Escherichia coli; Fermentation; Glucose; Hemiterpenes; Keto Acids; Lactococcus lactis; Metabolic Engineering; Pentanols; Temperature; Zymomonas	2015
High-performance liquid chromatographic method for profiling 2-oxo acids in urine and its application in evaluating vitamin status in rats. Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:2 Topics: Adipates; Animals; Biomarkers; Chromatography, High Pressure Liquid; Hemiterpenes; Keto Acids; Ketoglutaric Acids; Male; Oxaloacetic Acid; Pantothenic Acid; Phenylenediamines; Pyruvic Acid; Rats; Rats, Wistar; Spectrometry, Fluorescence; Thiamine; Thiamine Deficiency; Vitamin B 6; Vitamin B 6 Deficiency	2016
Metabolic Profiling of Total Physical Activity and Sedentary Behavior in Community-Dwelling Men. PloS one, 2016, Volume: 11, Issue:10 Topics: Adult; Aged; Amino Acids; Biomarkers; Electrophoresis, Capillary; Hemiterpenes; Humans; Keto Acids; Male; Mass Spectrometry; Metabolomics; Middle Aged; Motor Activity; Sedentary Behavior; Self Report; Surveys and Questionnaires	2016
Genotoxicity and sub-chronic toxicity of MYOLUTION Regulatory toxicology and pharmacology : RTP, 2017, Volume: 90 Topics: Animals; Cells, Cultured; Female; Food Ingredients; Healthy Volunteers; Hemiterpenes; Humans; Keto Acids; Lymphocytes; Male; Micronucleus Tests; No-Observed-Adverse-Effect Level; Rats, Wistar	2017
Valorization of soybean pulp for sustainable α-ketoisocaproate production using engineered Bacillus subtilis whole-cell biocatalyst. Chemosphere, 2023, Volume: 322 Topics: Animals; Bacillus subtilis; Carboxy-Lyases; Enoyl-CoA Hydratase; Glycine max; Leucine; Mammals	2023