alpha-ketobutyric acid has been researched along with pyruvic acid in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (28.57) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 10 (28.57) | 29.6817 |
| 2010's | 8 (22.86) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Halestrap, AP; Manning Fox, JE; Meredith, D | 1 |
| Coincon, M; Seah, SY; Sygusch, J; Wang, W | 1 |
| Barak, Z; Chipman, DM; Damri, B; Gollop, N | 1 |
| Barak, Z; Chipman, DM; Gollop, N | 2 |
| Brass, EP | 1 |
| Amos, H; Gomes, MI; Kim, WJ; Lively, MK | 1 |
| Amos, H; Groelke, J | 1 |
| Gabriel, M; Guerin, MC; Larcher, D; Marchand, J; Torreilles, J | 1 |
| Blanco, A; Burgos, C; Coronel, C; Gerez de Burgos, NM; Rovai, LE | 1 |
| Hübner, G; Khailova, LS; Neef, H; Schellenberger, A; Severin, SE | 1 |
| Hirota, K; Ikeda, M; Ohmori, S; Tanaka, Y | 1 |
| Schloss, JV; Tse, MT | 1 |
| Baskin, SI; Porter, DW | 1 |
| Andrews, SA; Huck, PM; Peldszus, S | 1 |
| Desagher, S; Glowinski, J; Prémont, J | 1 |
| Fotheringham, IG; Grinter, N; Pantaleone, DP; Senkpeil, RF; Taylor, PP | 1 |
| Chang, YY; Cronan, JE | 1 |
| Fukuda, E; Wakagi, T | 1 |
| COOKE, KB; ELLIOTT, BA; PLUMMER, DT; WILKINSON, JH | 1 |
| Antony, L; Carey, PR; Hall, PR; Pusztai-Carey, M; Yee, VC; Zheng, R | 1 |
| Eggeling, L; Kennerknecht, N; Marienhagen, J; Sahm, H | 1 |
| Drevland, RM; Graham, DE; Waheed, A | 1 |
| Coppi, MV; Lovley, DR; Orloff, A; Risso, C; Van Dien, SJ | 1 |
| Palmer, DR; Phenix, CP | 1 |
| Atsumi, S; Liao, JC | 1 |
| Bathe, B; Blombach, B; Eikmanns, BJ; Hans, S | 1 |
| Chua, JH; Deng, LW; Huang, S; Moore, PK; Sivaraman, J; Tan, CH; Yew, WS | 1 |
| Chen, N; Wang, J; Wen, B; Xie, X; Xu, Q; Zhang, C | 1 |
| Bok, RA; Kurhanewicz, J; Ohliger, MA; Vigneron, DB; von Morze, C; Zhu, Z | 1 |
| Bush, LN; Freinkman, E; Gui, DY; Hosios, AM; Sullivan, LB; Vander Heiden, MG | 1 |
| Li, Y; Liu, Y; Wang, X | 1 |
| Jiang, JF; Lei, F; Lu, X; Wang, XP; Xing, DM; Yan, XJ; Yu, X; Yuan, ZY | 1 |
| Glaser, RW; Hunt, JF; Jouhten, P; Maaheimo, H; Montelione, GT; Swapna, GVT; Szyperski, T; Xu, Y; Yu, XW; Zhang, M | 1 |
| Bezsudnova, EY; Boyko, KM; Popov, VO; Stekhanova, TN | 1 |
1 review(s) available for alpha-ketobutyric acid and pyruvic acid
| Article | Year |
|---|---|
Acetohydroxyacid synthases: evolution, structure, and function.
Topics: Acetolactate Synthase; Butyrates; Coenzymes; Evolution, Molecular; Hydroxybutyrates; Lactates; Protein Conformation; Pyruvic Acid; Thiamine Pyrophosphate | 2016 |
34 other study(ies) available for alpha-ketobutyric acid and pyruvic acid
| Article | Year |
|---|---|
Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle.
Topics: Animals; Biological Transport, Active; Carrier Proteins; Cells, Cultured; Fluoresceins; Fluorescent Dyes; Humans; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; Muscle, Skeletal; Oocytes; Protein Isoforms; Substrate Specificity; Xenopus | 2000 |
Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity.
Topics: Acetoacetates; Aldehyde-Lyases; Animals; Crystallography, X-Ray; Humans; Multienzyme Complexes; Protein Structure, Quaternary; Pyruvic Acid; Rabbits | 2012 |
Physiological implications of the substrate specificities of acetohydroxy acid synthases from varied organisms.
Topics: Acetolactate Synthase; Butyrates; Hydrogen-Ion Concentration; Oxo-Acid-Lyases; Pyruvates; Pyruvic Acid; Substrate Specificity | 1990 |
Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria.
Topics: Acetolactate Synthase; Butyrates; Escherichia coli; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoenzymes; Isoleucine; Kinetics; Lactates; Oxo-Acid-Lyases; Pyruvates; Pyruvic Acid; Salmonella typhimurium; Valine | 1987 |
A method for simultaneous determination of the two possible products of acetohydroxy acid synthase.
Topics: Acetolactate Synthase; Butyrates; Chromatography, Gas; Decarboxylation; Hydroxybutyrates; Kinetics; Lactates; Oxo-Acid-Lyases; Pyruvates; Pyruvic Acid | 1987 |
Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes.
Topics: Acyl Coenzyme A; Animals; Butyrates; Gluconeogenesis; Glucose; Keto Acids; Liver; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Pyruvates; Pyruvic Acid; Rats | 1986 |
Heat-shock treatment lethal for mammalian cells deprived of glucose and glutamine: protection by alpha-keto acids.
Topics: Animals; Blood; Butyrates; Cell Line; Cell Survival; Cricetinae; Fibroblasts; Glucose; Glutamine; Heat-Shock Proteins; Hot Temperature; Keto Acids; Ketoglutaric Acids; Oxaloacetates; Pyruvates; Pyruvic Acid | 1985 |
Transaminase inhibitors block glycolysis and G1 to S phase progression in chick embryo fibroblasts: reversal by alpha-keto acids.
Topics: Acetates; Aminooxyacetic Acid; Animals; Butyrates; Chick Embryo; Cycloserine; DNA Replication; Glycolysis; Insulin; Interphase; Keto Acids; Oxaloacetates; Pyruvates; Pyruvic Acid; Transaminases | 1984 |
The structure of the abortive nicotinamide adenine dinucleotide-pyruvate-lactate dehydrogenase complex as determined by circular dichroism.
Topics: Animals; Butyrates; Chromatography, Thin Layer; Circular Dichroism; L-Lactate Dehydrogenase; Multienzyme Complexes; NAD; Pyruvates; Pyruvic Acid; Swine | 1983 |
Properties of alpha-hydroxyacid dehydrogenase isozymes from Trypanosoma cruzi.
Topics: Alcohol Oxidoreductases; Animals; Butyrates; Hydroxy Acids; Isoenzymes; Keto Acids; Kinetics; L-Lactate Dehydrogenase; Lactate Dehydrogenases; Molecular Weight; Pyruvates; Pyruvic Acid; Substrate Specificity; Trypanosoma cruzi | 1981 |
Effect of pyruvate and its analogs on the thiamine pyrophosphate binding in the active center of muscle pyruvate dehydrogenase.
Topics: 2,6-Dichloroindophenol; Animals; Butyrates; Chemical Phenomena; Chemistry; Columbidae; Muscles; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Thiamine Pyrophosphate | 1982 |
A sensitive determination of alpha-keto acids by gas-liquid chromatography and its application to the assay of L-glutamate dehydrogenase and aminotransferases.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Butyrates; Chromatography, Gas; Glutamate Dehydrogenase; Humans; Hydrazines; Keto Acids; Ketoglutaric Acids; Oxaloacetates; Pyruvates; Pyruvic Acid; Time Factors | 1981 |
The oxygenase reaction of acetolactate synthase.
Topics: Acetolactate Synthase; Binding, Competitive; Butyrates; Calcium; Cations; Enzyme Activation; Kinetics; Magnesium; Manganese; Metals; Oxygen; Oxygenases; Pyruvates; Pyruvic Acid | 1993 |
The effect of three alpha-keto acids on 3-mercaptopyruvate sulfurtransferase activity.
Topics: Antidotes; Binding, Competitive; Butyrates; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Ketoglutaric Acids; Kinetics; Oxidation-Reduction; Pyruvic Acid; Reference Standards; Spectrophotometry, Ultraviolet; Sulfurtransferases | 1996 |
Determination of short-chain aliphatic, oxo- and hydroxy-acids in drinking water at low microgram per liter concentrations.
Topics: 3-Hydroxybutyric Acid; Acetic Acid; Butyrates; Butyric Acid; Carboxylic Acids; Chromatography, Ion Exchange; Drinking; Formates; Glycolates; Hydroxybutyrates; Pyruvic Acid; Water | 1996 |
Pyruvate protects neurons against hydrogen peroxide-induced toxicity.
Topics: Animals; Butyrates; Cells, Cultured; Corpus Striatum; Energy Metabolism; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ketoglutaric Acids; Lactic Acid; Mice; Neurons; Neuroprotective Agents; Oxaloacetates; Oxidation-Reduction; Oxidative Stress; Pyruvic Acid; Vitamin K | 1997 |
Engineering of a novel biochemical pathway for the biosynthesis of L-2-aminobutyric acid in Escherichia coli K12.
Topics: Acetolactate Synthase; Aminobutyrates; Aspartic Acid; Butyrates; Cloning, Molecular; Escherichia coli; Genetic Engineering; Pyruvic Acid; Recombinant Proteins; Threonine; Threonine Dehydratase; Transaminases | 1999 |
Conversion of Escherichia coli pyruvate oxidase to an 'alpha-ketobutyrate oxidase'.
Topics: Amino Acid Substitution; Butyrates; Enzyme Activation; Escherichia coli; Flavin-Adenine Dinucleotide; Ketone Oxidoreductases; Kinetics; Mutation; Pyruvate Oxidase; Pyruvic Acid; Substrate Specificity; Valine | 2000 |
Substrate recognition by 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus sp. strain 7.
Topics: Amino Acid Sequence; Binding Sites; Butyrates; Escherichia coli; Ketoglutaric Acids; Ketone Oxidoreductases; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Plasmids; Pyruvic Acid; Sequence Alignment; Substrate Specificity; Sulfolobus | 2002 |
Organ specificity and lactate-dehydrogenase activity. 1. The relative activities with pyruvate and 2-oxobutyrate of electrophoretically separated fractions.
Topics: Butyrates; Humans; L-Lactate Dehydrogenase; Lactates; Liver; Muscles; Myocardium; Organ Specificity; Pyruvates; Pyruvic Acid | 1963 |
Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Butyrates; Carboxyl and Carbamoyl Transferases; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Oxaloacetic Acid; Propionibacterium; Protein Binding; Protein Conformation; Protein Subunits; Pyruvate Carboxylase; Pyruvic Acid; Sequence Homology, Amino Acid | 2004 |
Functional analysis of all aminotransferase proteins inferred from the genome sequence of Corynebacterium glutamicum.
Topics: Alanine; Aspartic Acid; Bacterial Proteins; Butyrates; Carbon-Sulfur Lyases; Corynebacterium glutamicum; Gene Deletion; Glutamic Acid; Hemiterpenes; Keto Acids; Phenylpyruvic Acids; Pyruvic Acid; Substrate Specificity; Transaminases | 2005 |
Enzymology and evolution of the pyruvate pathway to 2-oxobutyrate in Methanocaldococcus jannaschii.
Topics: 3-Isopropylmalate Dehydrogenase; Aconitate Hydratase; Amino Acid Sequence; Archaeal Proteins; Butyrates; Escherichia coli; Evolution, Molecular; Hydro-Lyases; Isomerases; Malates; Maleates; Metabolic Networks and Pathways; Methanococcales; Molecular Sequence Data; Phylogeny; Protein Subunits; Pyruvic Acid; Recombinant Proteins; Sequence Alignment | 2007 |
Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens.
Topics: Acetyl Coenzyme A; Bacterial Proteins; Biosynthetic Pathways; Butyrates; Carbon Isotopes; Geobacter; Isoleucine; Malates; Pyruvic Acid; Threonine; Threonine Dehydratase | 2008 |
Isothermal titration microcalorimetry reveals the cooperative and noncompetitive nature of inhibition of Sinorhizobium meliloti L5-30 dihydrodipicolinate synthase by (S)-lysine.
Topics: Butyrates; Calorimetry; Hydro-Lyases; Lysine; Protein Binding; Pyruvic Acid; Sinorhizobium meliloti; Thermodynamics | 2008 |
Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli.
Topics: 1-Butanol; 1-Propanol; Acetyltransferases; Acyltransferases; Amino Acid Substitution; Biosynthetic Pathways; Butyrates; Enzyme Inhibitors; Escherichia coli; Glucose; Isoleucine; Methanococcus; Mutagenesis; Mutation, Missense; Polymerase Chain Reaction; Pyruvic Acid; Temperature | 2008 |
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum.
Topics: Acetolactate Synthase; Bacterial Proteins; Butyrates; Corynebacterium glutamicum; Enzyme Inhibitors; Gene Expression Profiling; Isoleucine; Kinetics; Leucine; Lysine; Pyruvic Acid; Sequence Deletion; Valine | 2009 |
Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production.
Topics: Amino Acid Substitution; Ammonia; Butyrates; Cystathionine; Cystathionine gamma-Lyase; Cysteine; Humans; Hydrogen Sulfide; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Pyridoxal Phosphate; Pyruvic Acid | 2010 |
Enhancing (L)-isoleucine production by thrABC overexpression combined with alaT deletion in Corynebacterium glutamicum.
Topics: Alanine Transaminase; Butyrates; Corynebacterium glutamicum; Escherichia coli Proteins; Fermentation; Gene Deletion; Gene Expression; Genetic Engineering; Intracellular Space; Isoleucine; Pyruvic Acid | 2013 |
Hyperpolarized [(13)C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH isoforms.
Topics: Animals; Butyrates; Carbon Isotopes; Cattle; Kidney; Kinetics; L-Lactate Dehydrogenase; Liver; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Muscles; Myocardium; Oxidation-Reduction; Protein Isoforms; Pyruvic Acid; Rabbits | 2016 |
Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells.
Topics: Adenosine Triphosphate; Aspartic Acid; Butyrates; Cell Line, Tumor; Cell Proliferation; Cell Respiration; Electrons; Humans; Mitochondria; Nucleotides; Pyruvic Acid | 2015 |
Mitochondria play an important role in the cell proliferation suppressing activity of berberine.
Topics: Berberine; Butyrates; Cell Line, Tumor; Cell Proliferation; Citric Acid Cycle; DNA, Mitochondrial; Dose-Response Relationship, Drug; Gene Dosage; Humans; Mitochondria; NAD; Pyruvic Acid | 2017 |
Topics: Aerobiosis; Batch Cell Culture Techniques; Butyrates; Carbon Isotopes; Citric Acid Cycle; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Magnetic Resonance Spectroscopy; Metabolome; Mitochondria; Pentose Phosphate Pathway; Pichia; Pyruvic Acid; Saccharomyces cerevisiae; Valine | 2017 |
Effect of Ketosubstrate on the Product Yield in the Transamination Reaction Catalyzed by Transaminase from Thermoproteus uzoniensis.
Topics: Archaeal Proteins; Butyrates; Catalysis; Hydrogen-Ion Concentration; Kinetics; Leucine; Pyruvic Acid; Substrate Specificity; Temperature; Thermoproteus; Transaminases | 2020 |