alpha-ketobutyric acid and isoleucine

alpha-ketobutyric acid has been researched along with isoleucine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19904 (18.18)18.7374
1990's4 (18.18)18.2507
2000's9 (40.91)29.6817
2010's4 (18.18)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
LaRossa, RA; Smulski, DR; Van Dyk, TK1
Barak, Z; Chipman, DM; Gollop, N1
Chibata, I; Crout, DH; Gregorio, MV; Kisumi, M; Komatsubara, S; Müller, US1
Burns, RO; Primerano, DA1
Eggeling, L; Möckel, B; Sahm, H1
Herring, PA; Jackson, JH; McKnight, BL1
Basso, AL; Caruso, C; De Felice, M; Ferrara, L; Ricca, E1
Eschenlauer, AC; Somers, DA; Srienc, F; Stoup, SK1
Flatt, PR; McClenaghan, NH1
Downs, DM; Schmitz, G1
Binder, S; Schuster, J1
Heinzle, E; Krömer, JO; Schröder, H; Wittmann, C1
Baldwin, IT; Giri, A; Kang, JH; Wang, L1
Kodera, T; Matrosov, NG; Novikova, AE; Ogawa, J; Rushkevich, NY; Samsonova, NN; Shimizu, S; Smirnov, SV; Yamanaka, H1
Coppi, MV; Lovley, DR; Orloff, A; Risso, C; Van Dien, SJ1
Atsumi, S; Liao, JC1
Bathe, B; Blombach, B; Eikmanns, BJ; Hans, S1
Chen, N; Wang, J; Wen, B; Xie, X; Xu, Q; Zhang, C1
Hemmi, H; Iimori, J; Ito, T; Moriyama, A; Takayama, S; Yamauchi, A; Yoshimura, T1
Brigham, CJ; Lu, J; Plassmeier, JK; Sinskey, AJ1
Glaser, RW; Hunt, JF; Jouhten, P; Maaheimo, H; Montelione, GT; Swapna, GVT; Szyperski, T; Xu, Y; Yu, XW; Zhang, M1
Bar-Even, A; Bernhardsgrütter, I; Burgener, S; Cotton, CA; De Maria, A; Dempfle, M; Dronsella, B; Erb, TJ; Erban, A; He, H; Kopka, J; Lindner, SN; Paczia, N; Schulz, L; Toman, S1

Other Studies

22 other study(ies) available for alpha-ketobutyric acid and isoleucine

ArticleYear
Toxic accumulation of alpha-ketobutyrate caused by inhibition of the branched-chain amino acid biosynthetic enzyme acetolactate synthase in Salmonella typhimurium.
    Journal of bacteriology, 1987, Volume: 169, Issue:4

    Topics: Acetolactate Synthase; Butyrates; DNA Transposable Elements; Isoleucine; Kinetics; Mutation; Oxo-Acid-Lyases; Salmonella typhimurium; Sulfonylurea Compounds; Valine

1987
Physiological implications of the specificity of acetohydroxy acid synthase isozymes of enteric bacteria.
    Journal of bacteriology, 1987, Volume: 169, Issue:8

    Topics: Acetolactate Synthase; Butyrates; Escherichia coli; Hydrogen-Ion Concentration; Hydroxybutyrates; Isoenzymes; Isoleucine; Kinetics; Lactates; Oxo-Acid-Lyases; Pyruvates; Pyruvic Acid; Salmonella typhimurium; Valine

1987
Stereochemistry of the conversions of L-threonine and D-threonine into 2-oxobutanoate by the L-threonine and D-threonine dehydratases of Serratia marcescens.
    European journal of biochemistry, 1980, Volume: 106, Issue:1

    Topics: Aminobutyrates; Butyrates; Deuterium; Isoleucine; Isotope Labeling; Serratia marcescens; Stereoisomerism; Threonine; Threonine Dehydratase

1980
Metabolic basis for the isoleucine, pantothenate or methionine requirement of ilvG strains of Salmonella typhimurium.
    Journal of bacteriology, 1982, Volume: 150, Issue:3

    Topics: Acetolactate Synthase; Aminobutyrates; Butyrates; Isoleucine; Methionine; Mutation; Pantothenic Acid; Salicylates; Salmonella typhimurium; Threonine Dehydratase; Transaminases

1982
Threonine dehydratases of Corynebacterium glutamicum with altered allosteric control: their generation and biochemical and structural analysis.
    Molecular microbiology, 1994, Volume: 13, Issue:5

    Topics: Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Butyrates; Corynebacterium; DNA-Directed DNA Polymerase; Isoleucine; Kinetics; Molecular Sequence Data; Mutagenesis; Protein Conformation; Protein Structure, Secondary; Pyridoxal Phosphate; Reproducibility of Results; Selection, Genetic; Sequence Alignment; Taq Polymerase; Threonine Dehydratase

1994
Channeling behavior and activity models for Escherichia coli K-12 acetohydroxy acid synthases at physiological substrate levels.
    Biochemical and biophysical research communications, 1995, Feb-06, Volume: 207, Issue:1

    Topics: Acetolactate Synthase; Amino Acids; Butyrates; Computer Simulation; Escherichia coli; Isoenzymes; Isoleucine; Kinetics; Pyruvates; Valine

1995
Acetohydroxy acid synthase and threonine deaminase activities, and the biosynthesis of isoleucine-leucine-valine in Streptococcus bovis.
    Research in microbiology, 1993, Volume: 144, Issue:7

    Topics: Acetolactate Synthase; Butyrates; Isoleucine; Leucine; Streptococcus bovis; Threonine Dehydratase; Valine

1993
Production of heteropolymeric polyhydroxyalkanoate in Escherichia coli from a single carbon source.
    International journal of biological macromolecules, 1996, Volume: 19, Issue:2

    Topics: Acyl Coenzyme A; Alcaligenes; Butyrates; Carbon; Cell Division; Culture Media; Escherichia coli; Glucose; Hydroxybutyrates; Isoleucine; Pentanoic Acids; Plasmids; Polyesters; Pyruvate Dehydrogenase Complex; Substrate Specificity; Threonine; Threonine Dehydratase; Transformation, Bacterial; Valine

1996
Metabolic and K(ATP) channel-independent actions of keto acid initiators of insulin secretion.
    Pancreas, 2000, Volume: 20, Issue:1

    Topics: Animals; Arginine; Butyrates; Calcium; Calcium Channel Blockers; Calcium Channels; Coumaric Acids; Diazoxide; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion Channel Gating; Ion Transport; Islets of Langerhans; Isoleucine; Keto Acids; Leucine; Membrane Potentials; Membrane Proteins; Mitochondria; Pancreatic Neoplasms; Phenylpyruvic Acids; Potassium Channels; Secretory Rate; Sodium Azide; Sodium Cyanide; Tumor Cells, Cultured; Valine; Verapamil

2000
Reduced transaminase B (IlvE) activity caused by the lack of yjgF is dependent on the status of threonine deaminase (IlvA) in Salmonella enterica serovar Typhimurium.
    Journal of bacteriology, 2004, Volume: 186, Issue:3

    Topics: Bacterial Proteins; Butyrates; Isoleucine; Operon; Salmonella typhimurium; Sulfonylurea Compounds; Threonine Dehydratase; Transaminases

2004
The mitochondrial branched-chain aminotransferase (AtBCAT-1) is capable to initiate degradation of leucine, isoleucine and valine in almost all tissues in Arabidopsis thaliana.
    Plant molecular biology, 2005, Volume: 57, Issue:2

    Topics: Amino Acids, Branched-Chain; Aminobutyrates; Arabidopsis; Arabidopsis Proteins; Butyrates; Deamination; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Glucuronidase; Hemiterpenes; Isoleucine; Keto Acids; Kinetics; Leucine; Methionine; Mitochondrial Proteins; Plants, Genetically Modified; Promoter Regions, Genetic; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Seedlings; Substrate Specificity; Transaminases; Transcription, Genetic; Valine

2005
Accumulation of homolanthionine and activation of a novel pathway for isoleucine biosynthesis in Corynebacterium glutamicum McbR deletion strains.
    Journal of bacteriology, 2006, Volume: 188, Issue:2

    Topics: Bacterial Proteins; Butyrates; Corynebacterium glutamicum; Gene Deletion; Homocystine; Isoleucine; Methionine; Repressor Proteins

2006
Silencing threonine deaminase and JAR4 in Nicotiana attenuata impairs jasmonic acid-isoleucine-mediated defenses against Manduca sexta.
    The Plant cell, 2006, Volume: 18, Issue:11

    Topics: Animals; Butyrates; Cyclopentanes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gene Silencing; Immunity, Innate; Isoleucine; Manduca; Molecular Sequence Data; Nicotiana; Nicotine; Oxylipins; Plant Diseases; Plant Leaves; Plant Viruses; RNA, Messenger; Signal Transduction; Suppression, Genetic; Threonine; Threonine Dehydratase; Trypsin Inhibitors

2006
A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity.
    FEMS microbiology letters, 2007, Volume: 273, Issue:1

    Topics: Acetaldehyde; Arthrobacter; Bacterial Proteins; Base Sequence; Butyrates; DNA, Bacterial; Fructose-Bisphosphate Aldolase; Glutamic Acid; Isoleucine; Molecular Sequence Data; Sequence Analysis, DNA; Transaminases

2007
Elucidation of an alternate isoleucine biosynthesis pathway in Geobacter sulfurreducens.
    Journal of bacteriology, 2008, Volume: 190, Issue:7

    Topics: Acetyl Coenzyme A; Bacterial Proteins; Biosynthetic Pathways; Butyrates; Carbon Isotopes; Geobacter; Isoleucine; Malates; Pyruvic Acid; Threonine; Threonine Dehydratase

2008
Directed evolution of Methanococcus jannaschii citramalate synthase for biosynthesis of 1-propanol and 1-butanol by Escherichia coli.
    Applied and environmental microbiology, 2008, Volume: 74, Issue:24

    Topics: 1-Butanol; 1-Propanol; Acetyltransferases; Acyltransferases; Amino Acid Substitution; Biosynthetic Pathways; Butyrates; Enzyme Inhibitors; Escherichia coli; Glucose; Isoleucine; Methanococcus; Mutagenesis; Mutation, Missense; Polymerase Chain Reaction; Pyruvic Acid; Temperature

2008
Acetohydroxyacid synthase, a novel target for improvement of L-lysine production by Corynebacterium glutamicum.
    Applied and environmental microbiology, 2009, Volume: 75, Issue:2

    Topics: Acetolactate Synthase; Bacterial Proteins; Butyrates; Corynebacterium glutamicum; Enzyme Inhibitors; Gene Expression Profiling; Isoleucine; Kinetics; Leucine; Lysine; Pyruvic Acid; Sequence Deletion; Valine

2009
Enhancing (L)-isoleucine production by thrABC overexpression combined with alaT deletion in Corynebacterium glutamicum.
    Applied biochemistry and biotechnology, 2013, Volume: 171, Issue:1

    Topics: Alanine Transaminase; Butyrates; Corynebacterium glutamicum; Escherichia coli Proteins; Fermentation; Gene Deletion; Gene Expression; Genetic Engineering; Intracellular Space; Isoleucine; Pyruvic Acid

2013
Conserved pyridoxal protein that regulates Ile and Val metabolism.
    Journal of bacteriology, 2013, Volume: 195, Issue:24

    Topics: Bacillus subtilis; Butyrates; Carrier Proteins; Coenzyme A; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Genetic Complementation Test; Isoleucine; Protein Binding; Pyridoxal Phosphate; Saccharomyces cerevisiae; Valine

2013
Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16.
    Applied microbiology and biotechnology, 2015, Volume: 99, Issue:2

    Topics: Acetolactate Synthase; Bacterial Proteins; Biosynthetic Pathways; Butyrates; Culture Media; Cupriavidus necator; DNA, Bacterial; Hemiterpenes; Hydro-Lyases; Isoleucine; Keto Acids; Ketol-Acid Reductoisomerase; Leucine; Mutagenesis, Site-Directed; Valine

2015
    The FEBS journal, 2017, Volume: 284, Issue:18

    Topics: Aerobiosis; Batch Cell Culture Techniques; Butyrates; Carbon Isotopes; Citric Acid Cycle; Glucose; Hemiterpenes; Isoleucine; Keto Acids; Leucine; Magnetic Resonance Spectroscopy; Metabolome; Mitochondria; Pentose Phosphate Pathway; Pichia; Pyruvic Acid; Saccharomyces cerevisiae; Valine

2017
Underground isoleucine biosynthesis pathways in
    eLife, 2020, 08-24, Volume: 9

    Topics: Butyrates; Carbon-Oxygen Lyases; Escherichia coli; Gene Deletion; Homoserine; Isoleucine; Metabolic Networks and Pathways

2020