alpha-hydroxymetoprolol has been researched along with dextromethorphan in 3 studies
| Studies (alpha-hydroxymetoprolol) | Trials (alpha-hydroxymetoprolol) | Recent Studies (post-2010) (alpha-hydroxymetoprolol) | Studies (dextromethorphan) | Trials (dextromethorphan) | Recent Studies (post-2010) (dextromethorphan) |
|---|---|---|---|---|---|
| 59 | 6 | 12 | 2,020 | 342 | 593 |
| Protein | Taxonomy | alpha-hydroxymetoprolol (IC50) | dextromethorphan (IC50) |
|---|---|---|---|
| Sodium channel protein type 1 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Sodium channel protein type 2 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Sodium channel protein type 3 subunit alpha | Rattus norvegicus (Norway rat) | 1.3 | |
| Cytochrome P450 2D26 | Rattus norvegicus (Norway rat) | 5.6 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 2.1768 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0027 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.1236 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Eddington, NE; Leslie, J; Mistry, B | 1 |
| Arseneault, M; Hamelin, BA; Labbé, L; Pilote, S; Robitaille, NM; Sirois, C; Turgeon, J | 1 |
| Claw, KG; Dalton, R; Dunham, MJ; Fade, M; Fowler, DM; Gaedigk, A; Lee, SB; McDonald, MG; Nickerson, DA; Phillips, BR; Prasad, B; Rettie, AE; Schuetz, E; Shen, DD; Thornton, TA; Thummel, KE; Wong, LH; Woodahl, EL | 1 |
3 other study(ies) available for alpha-hydroxymetoprolol and dextromethorphan
| Article | Year |
|---|---|
A sensitive assay of metoprolol and its major metabolite alpha-hydroxy metoprolol in human plasma and determination of dextromethorphan and its metabolite dextrorphan in urine with high performance liquid chromatography and fluorometric detection.
Topics: Adrenergic beta-Antagonists; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Dextrorphan; Humans; Indicators and Reagents; Metoprolol; Neuroprotective Agents; Quality Control; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence | 1998 |
Effect of gender, sex hormones, time variables and physiological urinary pH on apparent CYP2D6 activity as assessed by metabolic ratios of marker substrates.
Topics: Administration, Oral; Adult; Analysis of Variance; Biomarkers; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Enzyme Activation; Female; Gonadal Steroid Hormones; Humans; Hydrogen-Ion Concentration; Male; Menstrual Cycle; Metoprolol; Sex Characteristics; Sex Factors; Substrate Specificity; Time Factors; Urine | 2000 |
Interrogation of CYP2D6 Structural Variant Alleles Improves the Correlation Between CYP2D6 Genotype and CYP2D6-Mediated Metabolic Activity.
Topics: Alleles; Computational Biology; Cytochrome P-450 CYP2D6; Dextromethorphan; Dextrorphan; Genetic Association Studies; Genetic Loci; Haplotypes; High-Throughput Nucleotide Sequencing; Humans; Metoprolol; Microsomes, Liver; Pharmacogenomic Testing; Polymorphism, Genetic; Practice Guidelines as Topic | 2020 |