Page last updated: 2024-09-03

alpha-fluoromethylhistamine and histamine

alpha-fluoromethylhistamine has been researched along with histamine in 11 studies

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

*Histamine: An amine derived by enzymatic decarboxylation of HISTIDINE. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter. [MeSH]

Compound Research Comparison

Studies
(alpha-fluoromethylhistamine)
Trials
(alpha-fluoromethylhistamine)
Recent Studies (post-2010)
(alpha-fluoromethylhistamine)
Studies
(histamine)
Trials
(histamine)
Recent Studies (post-2010) (histamine)
120037,7181,3723,457

Protein Interaction Comparison

ProteinTaxonomyalpha-fluoromethylhistamine (IC50)histamine (IC50)
Histamine H1 receptorRattus norvegicus (Norway rat)0.1585
Histamine H1 receptorHomo sapiens (human)0.1585

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's7 (63.64)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adachi, N; Itoh, Y; Oishi, R; Saeki, K1
Bugajski, J; Turoń, M; Tytoń, J2
Bogdanovic, RP; Brandes, LJ; Davie, JR; LaBella, FS; Paraskevas, F; Sukhu, B1
Fujimoto, K; Fukagawa, K; Ookuma, K; Sakata, T; Wada, H; Yamatodani, A; Yoshimatsu, H1
Araki, Y; Fukuda, T; Itoh, Y; Nishibori, M; Oishi, R; Saeki, K1
Geiger, JD; Westerberg, VS1
Kang, M; Kurokawa, M; Oohara, A; Sakata, T; Yoshimatsu, H1
Mobarakeh, JI; Morimoto, T; Watanabe, T; Yamamoto, Y; Yamatodani, A; Yanai, K1
Håkanson, R; Lindström, E; Norlén, P1
Atanda, AM; Kazuhiko, Y; Kazuki, H; Masato, M; Yasuko, S1

Other Studies

11 other study(ies) available for alpha-fluoromethylhistamine and histamine

ArticleYear
Direct evidence for increased continuous histamine release in the striatum of conscious freely moving rats produced by middle cerebral artery occlusion.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:3

    Topics: Animals; Brain Chemistry; Brain Ischemia; Cerebral Infarction; Corpus Striatum; Disease Models, Animal; Histamine; Histamine Release; Male; Potassium Chloride; Rats; Rats, Inbred Strains

1992
The influence of alpha-fluoromethylhistidine and histamine receptor antagonists on the beta-endorphin-induced corticosterone response.
    Life sciences, 1991, Volume: 48, Issue:12

    Topics: Animals; beta-Endorphin; Brain; Corticosterone; Histamine; Histamine Antagonists; Injections, Intraventricular; Male; Naltrexone; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, Histamine

1991
The antiproliferative potency of histamine antagonists correlates with inhibition of binding of [3H]-histamine to novel intracellular receptors (HIC) in microsomal and nuclear fractions of rat liver.
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Animals; Binding Sites; Binding, Competitive; Cell Division; Cell Nucleus; DNA; Estrogen Antagonists; Histamine; Histamine Antagonists; Liver; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenyl Ethers; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Inbred Strains; Receptors, Histamine H1

1991
The significance of brain histamine and its receptors in opioid stimulation of the pituitary-adrenocortical activity.
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Adrenal Cortex; Animals; beta-Endorphin; Brain; Cimetidine; Corticosterone; Endorphins; Enkephalin, Leucine-2-Alanine; Histamine; Histidine Decarboxylase; Male; Morphine; p-Methoxy-N-methylphenethylamine; Pituitary Gland; Pyrilamine; Rats; Rats, Inbred Strains; Receptors, Histamine

1991
Hypothalamic neuronal histamine modulates ad libitum feeding by rats.
    Brain research, 1990, Dec-24, Volume: 537, Issue:1-2

    Topics: Animals; Brain Chemistry; Drinking Behavior; Feeding Behavior; Histamine; Histidine Decarboxylase; Hypothalamus; Injections, Intraventricular; Male; Neurons; Piperidines; Rats; Rats, Inbred Strains

1990
Histamine turnover in the brain of morphine-dependent mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:1

    Topics: Animals; Brain; Folic Acid Antagonists; Histamine; Histidine; Male; Methylhistamines; Mice; Mice, Inbred Strains; Morphine Dependence; Naloxone; Pargyline; Pyrimethamine; Substance Withdrawal Syndrome

1988
Inhibitors of histidine decarboxylase decrease basal gastric acid secretion in the rat.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:3

    Topics: Animals; Carboxy-Lyases; Gastric Acid; Histamine; Histidine Decarboxylase; Male; Methylhistidines; Rats; Rats, Inbred Strains; Stomach Ulcer

1987
Aminoglucose-induced feeding suppression is regulated by hypothalamic neuronal histamine in rats.
    Brain research, 1993, Dec-24, Volume: 631, Issue:2

    Topics: Acetylglucosamine; Animals; Appetite Depressants; Blood Glucose; Chlorpheniramine; Eating; Glucosamine; Histamine; Histamine H1 Antagonists; Histidine Decarboxylase; Hypothalamus; Injections, Intraventricular; Male; Neurons; Rats; Rats, Wistar

1993
Involvement of the histaminergic system in leptin-induced suppression of food intake.
    Physiology & behavior, 1999, Volume: 67, Issue:5

    Topics: Animals; Appetite Depressants; Eating; Enzyme Inhibitors; Feces; Histamine; Histidine Decarboxylase; Leptin; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, Histamine H1; Receptors, Leptin

1999
Histamine depletion does not affect pancreastatin secretion from isolated rat stomach ECL cells.
    European journal of pharmacology, 2000, Jan-03, Volume: 387, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cells, Cultured; Chromogranin A; Dose-Response Relationship, Drug; Gastric Mucosa; Histamine; Macrolides; Pancreatic Hormones; Rats; Reserpine

2000
Alpha-fluoromethylhistidine, a histamine synthesis inhibitor, inhibits orexin-induced wakefulness in rats.
    Behavioural brain research, 2010, Feb-11, Volume: 207, Issue:1

    Topics: Analysis of Variance; Animals; Arousal; Behavior, Animal; Electrodes, Implanted; Electroencephalography; Electromyography; Histamine; Histidine Decarboxylase; Intracellular Signaling Peptides and Proteins; Male; Neuropeptides; Orexins; Rats; Rats, Sprague-Dawley; Sleep; Wakefulness

2010